• Korean Journal of Animal Reproduction
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• v.24 no.1
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• pp.35-40
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• 2000

This experiment was conducted to investigate how restricted-lactation and regulation of weaning-time influence the levels of insulin-like growth factor-I (IGF-I) in primiparous rats during the suckling period. All the rats were raised in the individual cage from a few days before parturition through the whole suckling period. The restrictedlactation (RL) and weaned (W) groups were subdivided into 5 subgroups as RL0, RL5, RL10, RL15 and RL20 as well as W0, W5, Wl0, W15, and W20 according to the day of onset of suckling only 4 pups in restriction lactation and of suckling no pups in weaned group, respectively, in contrast to suckling 8 pups per litter in normal lactation (NL) group. The results obtained were summarized as follows: 1. The serum IGF- I concentration of NL rats was 750.59$\pm$3.52ng/$m\ell$ on Day 0, which was not changed until Day 15, and then it was increased through the subsequent suckling period to 1690.20$\pm$4.42ng/$m\ell$ on Day 25. 2. The IGF-I concentrations of early restricted lactation (RL0, RL5) were 1395.90$\pm$3.45ng/$m\ell$ and 1351$\pm$3.23ng/$m\ell$ on Day 10, respeotively. It was significantly higher (P＜0.05) than NL group (745.96$\pm$2.24ng/$m\ell$), and then was not different between group from day 15 of lactation. 3. The IGF- I concentration of W-group in the early lactation was higher (P＜0.05) than NL group during the first week of lactation. But it was decreased to the similar concentration as NL group on Day 10. These data show that lactation stimulus may regulate the IGF-I concentration.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.14 no.2
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• pp.175-183
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• 2002

Flow Condensation heat transfer coefficients (HTCs) of Rl2, R22, R32, Rl23, Rl25, R134a, R142b were measured experimentally on a horizontal plain tube. The experi- mental apparatus was composed of three main parts; a refrigerant loop, a water loop and a water-glycol loop. The test section in a refrigerant loop was made of a copper tube of 8.8 mm inner diameter and 1000 mm length respectively. The refrigerant was cooled by passing cold water through an annulus surrounding the test section. All tests were performed at a filed refrigerant saturation temperature of 4$0^{\circ}C$ with mass fluxes of 100, 200, 300 kg/$m^2$s. The experimental result showed that flow condensation HTCs increase as the quality, mass flux, and latent heat of condensation increase. At the same mass flux, the HTCs of R32 and R142b were higher than those of R22 by 35~45% and 7~14% respectively while HTCs of R134a and Rl23 were similar to those of R22. On the other hand, HTCs of Rl25 and Rl2 were lower than those of R22 by 28 ~30% and 15 ~25% respectively Finally, a new correlation for flow condensation HTCs was developed by modifying Dobson and Chato's correlation with the latent heat of condensation considered. The correlaton showed an average deviation of 13.1% for all pure fluids data indicating an excellent agreement.

• Korean Journal of Animal Reproduction
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• v.23 no.2
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• pp.95-103
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• 1999

This experiment was conducted to investigate how the lactation regulation such as restricted-lactation and early weaning during the suckling period influences on ovarian functions and change in serum levels of progesterone in primiparous rats. All the rats were raised in the individual cage from a few days before parturition through the suckling period. The normal lactation(NL) groups were controled 8 pups. The restricted-lactation(RL) and weaned(W) groups were subdivided into 5 subgroups as RL0, RL5, RL10, RL15 and RL20 as well as W0, W5, W10, W15, and W20 according to the day of onset of suckling. The number of pups were regulated from 8 to 4 on experimental strating day in RL gropus, and also perfectly weaned on the each on-set day in W groups. The results obtained were summarized as follows: 1. During the whole suckling period of 25 days the pups in RL group grew significantly(P＜005) faster than those in normal-lactation(NL) group. The pups in earlier RL group grew significantly(P＜0.05) faster than those in later RL rats, and there was no found any significant difference in body weight of pups between RL20 and NL group. The gestation period and litter size were found to be 21.53$\pm$0.04 days and 13.75$\pm$0.07, respectively. 2. The estrous cycle was not expressed in the NL group through the whole suckling period. An irregular estrous cycle was found around day 20 in RL0 group, and the regular estrous cycles were exhibited continuously from day 10 in the day 0 weaned rats. 3. In the rats of NL group the serum progesterone concentration increased from 33.16$\pm$2.64ng/$m\ell$ on day 0 to 122.5$\pm$53.68 ng/$m\ell$ on day 10, and then decreased slightly to 97.30$\pm$3.21 ng/$m\ell$ on day 20, but then decreased abruptly. However, the serum level of progesterone decreased greatly(P＜0.05) in 5 to 10 days following suckling restriction in the rats from which suckling began to be under restriction on day 0 or day 15. In the early weaning group the significant ( (P＜0.05) decrease in progesterone concentration was found similarly in 48 hours following weaning in all the rats weaned on day 0 through day 20. It was suggested that lactation stimulation is a very pivotal on the function of ovary.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.27 no.8
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• pp.1033-1041
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• 2003

Two-phase flow pattern data during horizontal in-tube flow boiling are presented for pure and mixed refrigerants of R134a and Rl23, The flow pattern is observed through tubular sight glasses located at inlet and outlet of the test section, which is made of a stainless steel tube, 2m long with 10mm I.D., 1.5mm wall thickness. The obtained results are compared with the available various correlations for flow pattern. The flow pattern map of Hashizume was in good agreement with the present data except the region of low mass velocity. Weisman flow pattern map was also known to satisfactorily predict data for refrigerants in the region of annular flow. In this study, the flow pattern are simply classified into two groups; stratified(including intermittent, stratified and stratified-wavy) flow and annular flow. The transition quality from stratified to annular flow was obtained by modifying the liquid Froude number.

• Journal of Korean Association for Spatial Structures
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• v.23 no.2
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• pp.29-36
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• 2023

Reinforcement learning (RL) is widely applied to various engineering fields. Especially, RL has shown successful performance for control problems, such as vehicles, robotics, and active structural control system. However, little research on application of RL to optimal structural design has conducted to date. In this study, the possibility of application of RL to structural design of reinforced concrete (RC) beam was investigated. The example of RC beam structural design problem introduced in previous study was used for comparative study. Deep q-network (DQN) is a famous RL algorithm presenting good performance in the discrete action space and thus it was used in this study. The action of DQN agent is required to represent design variables of RC beam. However, the number of design variables of RC beam is too many to represent by the action of conventional DQN. To solve this problem, multi-agent DQN was used in this study. For more effective reinforcement learning process, DDQN (Double Q-Learning) that is an advanced version of a conventional DQN was employed. The multi-agent of DDQN was trained for optimal structural design of RC beam to satisfy American Concrete Institute (318) without any hand-labeled dataset. Five agents of DDQN provides actions for beam with, beam depth, main rebar size, number of main rebar, and shear stirrup size, respectively. Five agents of DDQN were trained for 10,000 episodes and the performance of the multi-agent of DDQN was evaluated with 100 test design cases. This study shows that the multi-agent DDQN algorithm can provide successfully structural design results of RC beam.

• Journal of Environmental Impact Assessment
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• v.23 no.5
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• pp.337-352
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• 2014

The main purposes of this study are to find the causality among residents' loyalty to an environmental festival and its influential factors and, based upon the findings, to explore environmental festivals' developmental vision with special reference to Hampyung Butterfly Festival. Under these aims, this study applies structural equation modeling(SEM). The structural model for SEM analysis is composed of four independent variables which consist of residents' attachment(RA) to their region where its own environmental festival is provided, residents' participational intention(RP) to the festival, the economic effects(EE) of the festival, and the communication(CM) between the residents and the festival providers, one intermediate variable, residents' satisfaction(RS) from the festival, and one final dependent variable, residents' loyalty(RL) to the festival. The causality among these variables is hypothesized as follows; Among the independent variables, RP, EE, and CM have effects only on RS and RA has an effect on both RS and RL. And RS has an effect on RL. The facts found from the SEM are summed up as follows; First, (1) RP and CM turn out to have statistically significant effects on RS, (2) RA is confirmed to have a statistically very significant effect on both RS and RL, and (3) RS is also proved to show a statistically very significant effect on RL. Second, the total effects on RL of independent variables are stronger in the order of RA, CM, and RP. Third, EE seems to have no effect on RS, consequently no effect on RL, either. The reason why EE has no effect looks like to be due to environmental festivals' peculiar features. These findings offer the following suggestions for the future of environmental festivals in the part of festival providers. Firstly, to be successful in the festival, they have to provoke RL above all. Second, to do so, they need to encourage RA, CM, and RP in the mentioned order in the long run. Third, but for a short period, they had better concentrate upon promoting RS.

• Sleep Medicine and Psychophysiology
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• v.22 no.1
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• pp.20-24
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• 2015

Objectives: Restless legs syndrome (RLS) is a common sleep disorder in adults with diabetes. This study investigated the frequency of RLS and clinical correlations in children and adolescents with type 1 diabetes. Methods: This study included 55 consecutive patients (21 males, age $12.6{\pm}3.4years$) with type I diabetes that were regularly treated at the Department of Pediatric Endocrinology. RLS was diagnosed by intensive interviews which also included the Epworth Sleepiness Scale (ESS) and International RLS Rating Scale (IRLSRS). Patients also received neurological examinations and laboratory tests for diabetes, iron metabolism and renal function. Results: Thirteen patients (23.6%, 6 males) were compatible for the diagnostic criteria of RLS. None of the RLS patients showed abnormal findings in neurological evaluations and 7 patients had familial history of RLS. Demographic and laboratory findings were not different between the patients with or without RLS. The RLS group showed significantly increased ESS and IRLSRS scores. Conclusion: RLS was prevalent in children and adolescents with type 1 diabetes. The association between RLS and diabetes-related laboratory findings requires further investigation.

• Proceedings of the Korean Society of Crop Science Conference
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• 1999.05a
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• pp.22-23
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• 1999

• Journal of Pharmaceutical Investigation
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• v.23 no.2
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• pp.103-110
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• 1993

Microcapsules(Mc) of cephalexin (CEPH), using Eudragit RS, RL, L, S and polyethylene glycol 1540, were evaluated biopharmaceutically. The area under the curve of CEPH-Eudragit RS/RL Mc administered orally once was larger than that of cephalexin powder twice every 6 hrs. Controlledrelease effectiveness and the absorption rate effectiveness, two important parameters of Vallner's method, of CEPH-Eudragit RS/RL Mc indicate that these Mc can be good sustained-release preparations. And a simple pharmacokinetic model is introduced which allows the gastric emptying and intestinal-transit rates of a drug itself and a solid-state drug contained in Mc. Decreasing $K_r$, without change in $K_a$, showed that the rate-limiting step of absorption moved from absorption step to releasestep.

• Proceedings of the Korean Society of Crop Science Conference
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• 2018.04a
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• pp.23-23
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• 2018