• Asian Pacific Journal of Cancer Prevention
• /
• 제16권7호
• /
• pp.2619-2627
• /
• 2015

There are several studies that relate oxidative damage as possible mechanism for many cancers. Many studies have also shown that anti-oxidants like selenium and vitamin E decrease the risk for prostate cancer. The main objective of the Selenium and Vitamin E Cancer Prevention Trial (SELECT) study was to look for the benefits of selenium and vitamin E supplementation on prostate cancer. The study had a large sample size, stringent experimental conditions, very long duration, standardized laboratories for biochemical analyses and other factors that contribute to high external validity. The SELECT study failed to show any significant risk reduction for prostate cancers ascribable to selenium and vitamin E supplementations. Because of these conflicting results, many researchers argue about the methods used, supplementations administered (selenium and vitamin E) and indicators used for assessing levels of supplementations. We reviewed many epidemiological studies, clinical trials, and pre-clinical studies. With corroborative evidences we justify that SELECT study has a sound methodology and rationale. In lieu of the contrary results of the select study, researchers should focus on the probable mechanisms for these contrary findings and continue their search for newer and effective agents for prevention of prostate cancer.

• Journal of Preventive Medicine and Public Health
• /
• 제44권4호
• /
• pp.176-184
• /
• 2011

Objectives: Understanding recent trends in cigarette smoking among adolescents is important in order to develop strategies to prevent cigarette smoking. The aim of this study was to compare recent trends in cigarette smoking for adolescents living in rural areas, small towns and metropolitan cities in Korea. Methods: The raw data from the Korea Youth Risk Behavior Web-based Survey (KYRBWS) from 2005 to 2009 were used. Data were analyzed by using the method of complex survey data analysis considering complex sampling design. Logistic regression models were used to evaluate significant linear time trends in cigarette smoking. The indicators of cigarette use behaviors were 'current smoking rate', 'frequent smoking rate', 'heavy smoking rate' and 'smoking experience rate before 13 years of age'. All analyses were conducted according to gender. Results: Statistically significant increasing trends in current smoking rate and frequent smoking rate were observed and borderline significant increasing trends in heavy smoking rate were shown among rural boys. Among metropolitan city boys, statistically significant increasing trends were also seen for frequent smoking. Statistically significant decreasing trends in current smoking rate were observed among small town and metropolitan city girls. Smoking experience rate before 13 years of age for rural girls decreased significantly. Conclusions: Cigarette smoking prevalence among adolescents in the rural areas has increased in the last five years especially among boys. Our findings suggest that anti-tobacco program for adolescents should be conducted primarily for those in rural areas.

• 보건교육건강증진학회지
• /
• 제27권1호
• /
• pp.81-89
• /
• 2010

Objectives: To investigate the relationship between experience of hunger in childhood or adolescence and diabetes mellitus in old age. Methods: Stratified national samples of 421 men and 554 women aged 60-89 in South Korea were analyzed. Diabetes diagnosed by a doctor was used as the dependent variable. Experience of hunger in childhood was assessed with the question, "In your childhood, have you ever gone hungry with skipping a meal?" and "In your childhood, have you ever eaten porridge or some bran cake as main dish instead of rice because of lack of food?" Odds ratios (ORs) and 95% confidence interval (CI) were calculated by multiple logistic regressions. Results: ORs of diabetes by experience of hunger in childhood were 1.64(95% CI 0.95-2.83) for men and 1.58(95% CI 1.01-2.47) for women. Significant association of experience of hunger in childhood with prevalence of diabetes persisted in men after adjustment for adulthood and old age socioeconomic position indicators and other risk factors(OR 1.88(95% CI 1.04-3.41)). The effect of experience of hunger in 10-19 years was more prominent than that in less than 10 years in both gender. Conclusion: Experience of hunger in childhood or adolescence may increase the risk of diabetes in Korean elders.

• 한국전자거래학회지
• /
• 제22권4호
• /
• pp.117-128
• /
• 2017

비트코인의 국내 활용 증가와 함께 비트코인을 둘러싼 다양한 문제들이 발생하고 있다. 이에 따라 제도적 차원에서 비트코인을 어떻게 다루어야 하는지가 지속적으로 논의되고 있으며 비트코인의 자산 성격을 분류하는 것은 이러한 논의에 중요한 기준점이 될 것이다. 본 연구는 비트코인의 자산성격에 관한 선행연구들을 기초로 하여 기능적 측면에서 비트코인의 자산성격을 분류하였다. 회귀분석을 통해 금과 미소비자물가지수(CPI), 미달러화가치(DXY), 주가지수(S&P500) 등과의 상관관계를 분석하고, 비트코인과 동일지표들 간의 상관관계를 분석하여, 금과 비트코인이 지표들과의 관계에서 유사하게 반응하는지 검증하였다. 분석 결과 비트코인은 금과 유사한 방향성으로 보이며 인플레이션과 통화가치에 대해 위험회피기능과 수익률측면에서 투자가치를 지닌 투자자산기능을 확인할 수 있었다. 이러한 기능성과 더불어 투자자산기능의 주된 요인인 가격변동성을 고려하면, 비트코인은 화폐로 분류하기 보다는 고위험 금융투자자산으로 분류하여 제도권에 편입하는 것이 관리적 측면에서 효율적일 것이다.

• 한국학교보건학회지
• /
• 제28권2호
• /
• pp.79-88
• /
• 2015

The purpose of the study was to investigate mental health and mental health-related factors of adolescents with allergic diseases. Methods: The subjects were 72,060 middle and high school students, the data of whom were extracted from the 2014 Korean Youth' Risk Behavior Web-based Survey. Allergic diseases included asthma, allergic rhinitis and eczema. Mental health was measured by indicators such as perceived stress, depression, and suicidal ideation. To compare the mental health of adolescents who have allergic diseases with that of those who don't, the study used ${\chi}^2-test$ and calculated odds ratio (OR) and 95% confidence interval (CI). In addition, the study used ${\chi}^2-test$and multiple logistic regression, calculating OR and 95% CI, to analyze the association between mental health and allergic diseases and other variables. Results: Of 72,060 adolescents who participated in the study, 51.6% had allergic diseases(asthma 9.2%, allergic rhinitis 32.2%, eczema 23.9%). And 37.1% reported perceived stress, 26.6% depression, and 13.1% suicidal ideation. The adolescents with allergic diseases, compared to the adolescents without allergic diseases, were 1.26 times, 1.28 times, and 1.29 times more likely to experience perceived stress, depression, and suicidal ideation, respectively. The mental health-related factors of adolescents with allergic diseases were school type, sex, socioeconomic status, and academic performance. Conclusion: The adolescents with allergic diseases had poorer mental health than the adolescents without the diseases. Further studies should be done to verify this. And based on the study's findings, school-based intervention programs for mental health of adolescents with allergic diseases need to be developed.

• 문화기술의 융합
• /
• 제6권4호
• /
• pp.253-258
• /
• 2020

우울증은 전 세계적으로 유병율이 증가하고 있으며, 고혈압과 같은 여러 질병들뿐만 아니라 사망률과도 연관성이 높은 질병이다. 본 연구의 목적은 한국인 성인 중 단순노무종사자 직업군에서 우울증과 연관성이 있는 임상학적 위험지표를 발굴하는 것이다. 이러한 연구를 위한 데이터로는 질병관리본부 국민건강영양조사 7기 (2016-2018) 데이터가 사용되었다. 우울증과 인구학적 정보와의 연관성에서는 나이, 성별, 스트레스 인지정도, 스트레스 인지율 지표들이 우울증과 매우 높은 통계적 연관성이 나타났고, 교육과 결혼유무도 우울증과 연관성이 있는 것으로 나타났다. 복부둘레 및 체질량지수와 같은 비만 지표들은 우울증과 연관성이 없는 것으로 나타났다. 혈액정보 중 hemoglobin과 hematocrit은 우울증과 연관성이 매우 높은 것으로 나타났으며, 성별과 나이로 보정한 분석에서도 통계적 유의성이 유지되었다. 본 연구결과는 향후 단순노무종사자 직업군의 우울증 예방 및 치료를 위한 정보로 활용가능할 것이다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제22권4호
• /
• pp.294-301
• /
• 2011

Objectives : This study investigated factors related to suicide in high school students and focused on perceived academic performance. Methods : We surveyed 293 grade 10 high-school students in Jeju and Gyeonggi provinces and gave them self-assessment questionnaires. To evaluate the suicide risk, the questionnaire included questions about suicidal thoughts, plans, threats, deliberate self-injury, and suicide attempts from the Scale for Suicide Ideation (SSI). Also, it included the Beck Depression Inventory (BDI), Beck Hopelessness Scale (BHS), Locus of Control Scale (LOC), Rosenberg's Self Esteem Scale (RSE) and Perceived Academic Performance (PAP) to identify factors related to suicide in high school students. Results : Depression, hopelessness, and low self-esteem were related with suicidal thoughts, plans, attempts, and severe suicidal ideation (SSI score${geq}$16). In the multivariate analysis, a low level of PAP (OR=3.796, 95%CI 1.280-11.257) was significantly associated with severe suicidal ideation (SSI score${geq}$16). Deliberate self-injury was most prevalent in failing the PAP group and also having a high level of PAP (OR=6.161, 95%CI 1.474-25.760). Conclusion : The authors found that the suicide risk of high school students is related to depression, hopelessness, low self-esteem and a low level of PAP. These results provide significant indicators in planning an adolescent suicide prevention program.

• Preventive Nutrition and Food Science
• /
• 제8권1호
• /
• pp.70-74
• /
• 2003

This study investigated the relationship of Helicobacter pylori (H. pylori) infection to iron-deficiency anemia in high school girls. Four hundred and fourty-five subjects resided in Ulsan City in Korea were evaluated by questionnaire or blood analysis for serum indicators of iron status, daily nutrient intakes, symptoms of anemia, and H. pylori IgG antibody status. In H. pylori infected subjects, total energy intake of was 1534.14±350.81 kcal (73.0% of the Korean RDA), the iron intake of subjects was 11.38±3.90 mg (71.1% of Korean RDA) and calcium intake was 467.63±175.96 mg (58.3% of the Korean RDA). Carbohydrate (p < 0.05), vitamin A (p < 0.05), vitamin C (p < 0.01) intakes were significantly lower in infected subjects than in non-infected subjects. The prevalence of anemia (hemoglobin (Hb) < 12 g/dL.) in H. pylori infected subjects was 22.7% as compared to 14.7% in non-infected subjects. The mean serum ferritin of infected subjects (21.71±21.50 ng/mL) was significantly lower than in non-infected subjects (p < 0.05) (as was the mean Hb concentration (12.54±1.51 g/dL) and hematocrit (37.99±3.64%)). Total iron binding capacity (TIBC) of H. pylori infected subjects (449.09±78.23 ㎍/dL) was significantly higher than that of non-infected subjects (432.99＋76.15 ㎍/dL) (P < 0.05). The levels of iron, red blood cell (RBC) and transferrin saturation were similar in infected and non-infected subjects. Two symptoms of anemia, 'pale face (p < 0.01)' and 'decreased ability to concentrate (p < 0.005)', were significantly higher in H. pylori infected subjects than in non-infected subjects. High school girls are known to be more vulnerable to iron deficiency than other age groups, and this research demonstrates that infection with H. pylori increases their risk of iron-deficiency anemia.

• 보건행정학회지
• /
• 제28권1호
• /
• pp.15-22
• /
• 2018

Background: Health is affected by various local factors. This study aims to investigate the age-standardized mortality variation of Seoul as well as the characteristics of the factors related to the mortality variation. Methods: The Korea Community Health Survey data, Seoul Survey data, Seoul statistics, and e-regional indicators of the National Statistical Office were used. To investigate the basic boroughs standardized mortality variation in Seoul, external quotient, coefficient of variation (CV), and systematic component of variation (SCV) values were suggested; correlation analysis and multiple regression analysis were conducted to investigate the characteristics related to standardized mortality rate. Results: The highest and the lowest standardized mortality rate of Seoul by boroughs had as much as 1.4 times difference; a low level of variation was shown in CV by 8.2; and was shown in SCV by 79. As a result of the multiple regression analysis of the factors that affect standardized mortality variation, the higher the rate of householders with college or higher, the lower the standardized mortality rate, and the higher the high-risk drinking rate, the higher the standardized mortality rate. Of the two, the rate of householder with a degree equivalent or higher than college was shown to have the biggest impact, followed by high-risk drinking rate. Conclusion: We found a variation in age-standardized mortality rate of boroughs in Seoul. The results suggest that policy makers should take into account socioeconomic environmental characteristics of community in developing community-based health promotion rather than focusing on lifestyle changes of residents.

• 대한한방내과학회지
• /
• 제40권4호
• /
• pp.649-662
• /
• 2019

Objective: The purpose of this study was to investigate the effect of electroacupuncture on acute pancreatitis (AP). Method: The search engines that were used included PubMed, CNKI, OASIS, NDSL, the Korean Traditional Knowledge Portal, and J-STAGE. The search period was from the creation of the search engine to May 6, 2019; there were no language limitations. Extractions and selections from the literation were made by two authors. The study included randomized controlled trials with electroacupuncture for patients with acute pancreatitis. Cochrane's risk of bias (RoB) was used as the methodological quality assessment scale. Results: Nine studies were finally selected. It was observed that using electroacupuncture with general Western medicine treatment for AP was more effective than using only general Western medicine treatment. Although most of the studies showed a high risk of bias, there were significant differences among the indicators. Conclusion: The electroacupuncture treatment with Western medicine may be more effective in reducing symptoms of AP than Western medicine alone. However, due to the limitations of the research design, it was not enough to obtain reliable information. As a result, high quality research will be additionally required.