• 한국방사선학회논문지
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• 제13권4호
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• pp.539-546
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• 2019

간조직 생검은 침습적이며, 합병증의 위험을 동반함에도 불구하고 간섬유화의 정도를 예측하는 표준 진단법으로 적용된다. 이러한 단점을 보완하기 위해 본 연구에서는 만성 C형간염 환자 200명을 대상으로 Fibroscan(R)을 이용하여 간섬유화 등급을 나누고, ROC 곡선을 측정하여 혈청학적검사로 계산되는 FIB-4, APRI, AAR의 유용성과 실질적인 Cut-off value를 알아보고자 하였다. 그 결과 간섬유화 평가를 위해 AAR을 적용하는 것보다는 APRI, FIB-4를 이용하는 것이 적절할 것으로 생각되며, 경한 섬유화 등급을 예측하기 위해서는 APRI, 간경변군인 F4등급에는 FIB-4를 사용하는 것이 유용하다고 판단된다. 혈청학적 간섬유화 표지자의 간편하고 반복 측정이 가능하다는 장점을 이용해 간 섬유화의 경과 관찰 기간을 줄일 수 있으므로 나아가 간경변과 간암의 유병률을 감소시킬 수 있을 것으로 사료된다.

• 한국토양비료학회지
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• 제44권6호
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• pp.1004-1009
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• 2011

Soil erosion in North Korea has been continued to accelerate by deterioration of topographical conditions. However, few studies have been conducted to predict the amount of soil loss in North Korea due to limited data so far. Rainfall erosivity is an important factor to predict the amount of long-term annual soil loss by USLE (universal soil loss equation). The purpose of this study is to investigate rainfall erosivity, which presented the potential risk of soil erosion by water, in North Korea. Annual rainfall erosivities for 27 stations in North Korea for 1983~2010 were calculated using regression models based on modified Institute of Agricultural Sciences (IAS) index in this study. The result showed that annual average rainfall erosivity in North Korea ranged from 2,249 to 7,526 and averaged value was $4,947MJmm\;ha^{-1}\;hr^{-1}\;yr^{-1}$, which corresponded to about 70% of annual average rainfall erosivity in South Korea. The finding was that the potential risk of soil erosion in North Korea has been accelerated by the increase of rainfall erosivity since the late 1990s.

• Journal of the Korean Data and Information Science Society
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• 제25권6호
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• pp.1333-1343
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• 2014

본 연구는 일변량 금융지수의 변동성 모형에서 GARCH(1,1) 모형이 여러 복잡한 GARCH 확장 모형에 비교해서 결코 뒤쳐지지 않는다는 Hansen과 Lunde (2005) 연구를 다변량 변동성으로 확장한다. 또한 모형의 비교 방법으로 예측값에 기반한 평균제곱예측오차 (MSPE) 뿐 만 아니라 리스크 관리 측면에서 최대 손실 금액을 나타내는 VaR 및 사후 검정인 실패율을 동시에 고려하였다. 모의실험 결과 다변량 변동성의 경우에서도 GARCH 모형이 예측력은 크게 다르지는 않았으나 리스크 관리 측면에서는 좀 더 신중한 판단을 요구함을 보인다. 또한 최근 10년동안의 KOSPI, NASDAQ 및 HANG SENG의 주가 지수 실증 자료를 통하여 리스크 관리 측면에서의 다변량 GARCH 모형 선택에 대해서 논의한다.

• Tuberculosis and Respiratory Diseases
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• 제67권5호
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• pp.430-435
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• 2009

Background: Thus far, research studies on community-acquired pneumonia (CAP) have focused on its clinical severity. Recently, it has been determined that procalcitonin (PCT) level is correlated with severity of CAP. A retrospective study conducted at our hospital used risk predictability and PCT to determine whether or no PCT is useful in assessing the severity of CAP. Methods: This study covered 92 CAP cases that were admitted to the respiratory department at Changwon Fatima Hospital between July 1, 2008 and June 30, 2009. All enrolled subjects were measured for infection markers and risk predictability. Results: Based on hospital admission data, enrolled subjects had Pneumonia Severity Index (PSI) scores serving as risk predictors showed that both PCT and white blood cell (WBC) were statistically significant as infection markers (p=0.001, 0.037). Thus, this study used ROC curves in PSI for data analysis. As a result, it was determined that the area under curve (AUC) of PCT and WBC was 0.694 and 0.593 respectively, indicating that PCT has a higher test value for WBC, when PCT was higher than 0.745 ng/mL. In addition, it was found that PCT levels higher than 0.745 ng/mL had higher PSI scores than the group with PCT lower than 0.745 ng/mL (p=0.032). Conclusion: In order to predict risk of pneumonia cases admitted due to symptoms of CAP, it is important to consider PCT as well as PSI, and follow-up monitoring of PCT cases.

• 한국생활환경학회지
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• 제19권4호
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• pp.479-488
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• 2012

This study investigated the influence of the indoor CO₂concentration level on sleep quality by polysomnography(PSG). One healthy female subject was selected among several subjects based on RI(Risk Indicator) value and BMI(Body Mass Index) value to evaluate judging the risk level of obstructive sleep apnea hypopnea. To get the impact of the indoor carbon dioxide concentration to sleep quality, both CO₂concentration levels were set up using ventilating form with 700~800 ppm and 2000~3000 ppm. Other environments were controlled in the comfortable sleep scope by previous researches. To measure the sleep quality, measurements have carried on polysomnography(PSG). In conclusion, it have shown that high carbon dioxide concentration leads arousal effect about central nervous system and to sustaining dreams and excited condition by bring about REM sleep split phenomenon.

• 응용통계연구
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• 제21권4호
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• pp.571-580
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• 2008

로지스틱회귀분석은 고객관계관리나 신용위험관리 등의 분야에서 많이 사용되는 기법인데, 이러한 분야에서의 로지스틱회귀모형에는 연관성이 높은 설명변수들이 다수 포함되어 다중공선성의 문제를 유발하는 경우가 있다. 다중공선성이 존재하는 상황에서 최우추정량은 심각한 결함을 갖는다는 사실은 잘 알려졌다. 이 문제를 해결하기 위하여 로지스틱주성분회귀를 연구하되, 분석상의 주요 과정인 주성분 선정을 위한 방법을 새롭게 제안하였다. 추정량의 분산을 최소가 되게 하는 상태지수 값을 측정하고, 이 값에 영향을 미치는 주요 요인들을 컨조인트분석에 의해 파악하여 주성분 선정기준을 결정하는 모형을 구축하였다. 제안된 방법은 다중공선성 문제를 적절히 해결하면서도 모형의 적합성을 향상시킨다는 사실이 모의실험을 통하여 확인되었다.

• 한국토양비료학회지
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• 제44권1호
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• pp.38-47
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• 2011

This study focused on health risk assessment via multi-routes of As exposure to establish a target cleanup level (TCL) in abandoned mines. Soil, ground water, and rice samples were collected near ten abandoned mines in November 2009. The As contaminations measured in all samples were used for determining the probabilistic health risk by Monte-Carlo simulation techniques. The human exposure to As compound was attributed to ground water ingestion. Cancer risk probability (R) via ground water and rice intake exceeded the acceptable risk range of $10^{-6}{\sim}10^{-4}$ in all selected mines. In particular, the MB mine showed the higher R value than other mines. The non-carcinogenic effects, estimated by comparing the average As exposure with corresponding reference dose were determined by hazard quotient (HQ) values, which were less than 1.0 via ground water and rice intake in SD, NS, and MB mines. This implied that the non-carcinogenic toxic effects, due to this exposure pathway had a greater possibility to occur than those in other mines. Besides, hazard index (HI) values, representing overall toxic effects by summed the HQ values were also greater than 1.0 in SD, NS, JA, and IA mines. This revealed that non-carcinogenic toxic effects were generally occurred. The As contaminants in all selected mines exceeded the TCL values for target cancer risk ($10^{-6}$) through ground water ingestion and rice intake. However, the As level in soil was greater than TCL value for target cancer risk via inadvertent soil ingestion pathway, except for KK mine. In TCL values for target hazard quotient (THQ), the As contaminants in soil did not exceed such TCL value. On the contrary, the As levels in ground water and polished rice in SD, NS, IA, and MB mines were also beyond the TCL values via ground water and rice intake. This study concluded that the health risks through ground water and rice intake were greater than those though soil inadvertent ingestion and dermal contact. In addition, it suggests that the abandoned mines to exceed the risk-based TCL values are carefully necessary to monitor for soil remediation.

• 한국전문물리치료학회지
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• 제31권2호
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• pp.91-103
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• 2024

Stroke is one of the most common disabilities experienced by the elderly in the community. However, stroke progresses to a chronic level, patients are discharged from medical institutions and eventually no longer receive therapeutic interventions at home. In this systematic review, we compared home-based rehabilitation (HBR) with comparison for patients with stroke. Literature published in Cumulative Index for Nursing and Allied Health Literature (CINAHL), Embase, Physiotherapy Evidence Database (PEDro), PubMed, and Google Scholar were reviewed. A total of 1,158 studies were initially retrieved. After reading the full texts, 11 articles were included in the systematic review. Quality assessment of the included studies was conducted using Risk of Bias (RoB) 2.0, and Egger's regression test was used to evaluate publication bias. Data analysis was performed using the R studio software (R Studio). According to the quality assessment using RoB 2.0, three studies were evaluated as low risk, two as of some concern, and three as high risk. The overall effect size was moderate (0.309). The value of the balance function was a small effect size (0.201), while the value of the gait function was a moderate effect size (0.353). The values were small and moderate effect (0.154, 0.411) for the chronic and subacute conditions, respectively. According to the Egger's regression test, no publication bias was observed. The findings of this study indicate that HBR resulted in the greatest improvement in gait function in patients with subacute stroke compared to those with chronic stroke. Therefore, the application of this intervention to patients with stroke in the community is recommended.

• 국제지역연구
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• 제12권2호
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• pp.3-26
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• 2008

본 논문은 호주 금융시장의 두 가지 시계열(ASX200 주가지수와 AUD/USD 환율)의 수익률 자료에 존재할 수 있는 장기기억 변동성 특성을 모형화하는 데 skewed Student-t 분포가 유용한지를 연구한다. 이러한 연구목적을 위하여 FIGARCH 및 FIAPARCH Value-at-Risk (VaR) 모형을 교란항에 대한 정규분포, Student-t 분포 및 치우친 Student-t 분포 가정하에서 평가한다. 실증분석 결과 skewed Student-t 분포 모형이 정규분포 모형이나 Student-t 분포 모형보다 호주 금융시장의 VaR을 더 정확하게 추정한다는 발견하였다. 따라서 자산 수익률 분포의 왜도 및 첨도를 고려하는 것은 호주 주식시장과 외환시장의 장기기억 변동성 모형을 검토할 때 적절한 모형선택 기준을 제공한다는 것을 알 수 있다.

• Earthquakes and Structures
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• 제11권4호
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• pp.629-648
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• 2016

This paper deals with 111 buildings built between 1962 and 1987, from various parts of the city of Osijek, for which, through the collection of documentation, a database is created. The aim of this paper is to provide the first steps in assessing seismic risk in Osijek applying method based on vulnerability index. This index uses collected information of parameters of the building: the structural system, the construction year, plan, the height, i.e., the number of stories, the type of foundation, the structural and non-structural elements, the type and the quality of main construction material, the position in the block and built-up area. According to this method defining five damage states, the action is expressed in terms of the macroseismic intensity and the seismic quality of the buildings by means of a vulnerability index. The value of the vulnerability index can be changed depending on the structural systems, quality of construction, etc., by introducing behavior and regional modifiers based on expert judgments. Since there is no available data of damaged buildings under earthquake loading in our country, we will propose behavior modifiers based on values suggested by earlier works and on judgment based on available project documentation of the considered buildings. Depending on the proposed modifiers, the seismic vulnerability of existing buildings in the city of Osijek will be assessed. The resulting vulnerability of the considered residential buildings provides necessary insight for emergency planning and for identification of critical objects vulnerable to seismic loading.