• Title/Summary/Keyword: Risk assessment Model

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Affecting Factors of Insulin Resistance in Obese Children and Adolescents (소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인)

  • Kim, Duk Hee;Eun, Ho Seon;Choi, In Kyung;Kim, Ho Seung;Cha, Bong Soo;Kim, Dong Kee
    • Clinical and Experimental Pediatrics
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    • v.48 no.10
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    • pp.1076-1081
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    • 2005
  • Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods : Of the 9,837 school children from 5 to 16 tears old, 92 obese children and 187 adolescent, underwent a two-hour oral glucose tolerance test and plasma glucose, insulin, lipid profiles, leptin and high sensitive C-reactive protein(hs-CRP) were measure. Results : Plasma insulin levels of female were higher compared to those of males during oral glucose tolerance test(P<0.05). Four(4.3%) in obese children and twenty five(13.3%) in obese adolescents met the criteria of IGT. Female, leptin, adiponectin and triglyceride concentrations were strongly correlated with homeostatic model assessment insulin-resistance(HOMA-IR) by multiple linear regression analysis(P<0.05). Conclusion : Obese adolescents might have higher insulin concentrations compared to obese children and obese girls higher insulin concentrations than obese boys. Obese boys and children with impaired glucose tolerance have higher insulin concentrations than those with normal glucose tolerance. HOMA-IR was significantly correlated with female, plasma leptin, adiponectin and triglyceride concentrations.

Comparison of Hospital Standardized Mortality Ratio Using National Hospital Discharge Injury Data (퇴원손상심층조사 자료를 이용한 의료기관 중증도 보정 사망비 비교)

  • Park, Jong-Ho;Kim, Yoo-Mi;Kim, Sung-Soo;Kim, Won-Joong;Kang, Sung-Hong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.4
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    • pp.1739-1750
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    • 2012
  • This study was to develop the assessment of medical service outcome using administration data through compared with hospital standardized mortality ratios(HSMR) in various hospitals. This study analyzed 63,664 cases of Hospital Discharge Injury Data of 2007 and 2008, provided by Korea Centers for Disease Control and Prevention. We used data mining technique and compared decision tree and logistic regression for developing risk-adjustment model of in-hospital mortality. Our Analysis shows that gender, length of stay, Elixhauser comorbidity index, hospitalization path, and primary diagnosis are main variables which influence mortality ratio. By comparing hospital standardized mortality ratios(HSMR) with standardized variables, we found concrete differences (55.6-201.6) of hospital standardized mortality ratios(HSMR) among hospitals. This proves that there are quality-gaps of medical service among hospitals. This study outcome should be utilized more to achieve the improvement of the quality of medical service.

A Study on Residual Strength Assessment of Damaged Oil Tanker by Smith Method (Smith법에 의한 손상 유조선의 잔류강도 평가 연구)

  • Ahn, Hyung-Joon;Baek, Deok-Pyo;Lee, Tak-Kee
    • Journal of Navigation and Port Research
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    • v.35 no.10
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    • pp.823-827
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    • 2011
  • The present Common Structural Rules for double hull oil tanker is not included the residual strength, which is one of the functional requirements in design part of Goal-based new ship construction standards (GBS). The GBS will be enforced after July 1, 2016. The requirement related residual strength has the goal to build safe ship even if she has the specified damages due to marine accidents including collision and grounding. In order to assess the residual strength based on risk for structural damages according to GBS, tons of nonlinear FE analysis work taking into account various types of damage will be needed. The Smith's method, a kind of simplified method for the strength analysis is very useful for this purpose. In this paper, the residual strength assessments based on ultimate strength using Smith's method were carried out. The objected ship is VLCC with stranding damage in bottom structures. Also, the results were compared with that of nonlinear FE analysis using three cargo hold model.

Inhalation Toxicity of Particulate Matters Doped with Arsenic Induced Genotoxicity and Altered Akt Signaling Pathway in Lungs of Mice

  • Park, Jin-Hong;Kwon, Jung-Taek;Minai-Teherani, Arassh;Hwang, Soon-Kyung;Chang, Seung-Hee;Lim, Hwang-Tae;Cho, Hyun-Seon;Cho, Myung-Haing
    • Toxicological Research
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    • v.26 no.4
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    • pp.261-266
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    • 2010
  • In the workplace, the arsenic is used in the semiconductor production and the manufacturing of pigments, glass, pesticides and fungicides. Therefore, workers may be exposed to airborne arsenic during its use in manufacturing. The purpose of this study was to evaluate the potential toxicity of particulate matters (PMs) doped with arsenic (PMs-Arsenic) using a rodent model and to compare the genotoxicity in various concentrations and to examine the role of PMs-Arsenic in the induction of signaling pathway in the lung. Mice were exposed to PMs $124.4{\pm}24.5\;{\mu}g/m^3$ (low concentration), $220.2{\pm}34.5\;{\mu}g/m^3$ (middle concentration), $426.4{\pm}40.3\;{\mu}g/m^3$ (high concentration) doped with arsenic $1.4\;{\mu}g/m^3$ (Low concentration), $2.5\;{\mu}g/m^3$ (middle concentration), $5.7\;{\mu}g/m^3$ (high concentration) for 4 wks (6 h/d, 5 d/wk), respectively in the whole-body inhalation exposure chambers. To determine the level of genotoxicity, Chromosomal aberration (CA) assay in splenic lymphocytes and Supravital micronucleus (SMN) assay were performed. Then, signal pathway in the lung was analyzed. In the genotoxicity experiments, the increases of aberrant cells were concentration-dependent. Also, PMs-arsenic caused peripheral blood micronucleus frequency at high concentration. The inhalation of PMs-Arsenic increased an expression of phosphorylated Akt (p-Akt: protein kinase B) and phpsphorylated mammalian target of rapamycin (p-mTOR) at high concentration group. Taken together, inhaled PMs-Arsenic caused genotoxicity and altered Akt signaling pathway in the lung. Therefore, the inhalation of PMs-Arsenic needs for a careful risk assessment in the workplace.

Impact Assessment of Climate Change on Drought Risk (기후변화가 가뭄 위험성에 미치는 영향 평가)

  • Kim, Byung-Sik;Kwon, Hyun-Han;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • v.13 no.1
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    • pp.1-11
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    • 2011
  • A chronic drought stress has been imposed during non-rainy season(from winter to spring) since 1990s. We faced the most significant water crisis in 2001, and the drought was characterized by sultry weather and severe drought on a national scale. It has been widely acknowledged that the drought related damage is 2-3 times serious than floods. In the list of the world's largest natural disaster compiled by NOAA, 4 of the top 5 disasters are droughts. And according to the analysis from the NDMC report, the drought has the highest annual average damage among all the disasters. There was a very serious impact on the economic such as rising consumer price during the 2001 spring drought in Korea. There has been flood prevention measures implemented at national-level but for mitigation of droughts, there are only plans aimed at emergency (short-term) restoration rather than the comprehensive preventive measures. In addition, there is a lack of a clear set of indicators to express drought situation objectively, and therefore it is important and urgent to begin a systematic study. In this study, a nonstationary downscaling model using RCM based climate change scenario was first applied to simulate precipitation, and the simulated precipitation data was used to derive Standardized Precipitation Index (SPI). The SPI under climate change was used to evaluate the spatio-temporal variability of drought through principal component analysis at three different time scales which are 2015, 2045 and 2075. It was found that spatio-temporal variability is likely to modulate with climate change.

Priority assessment and estimation of annual power generation for potential development site of hydroelectric dam in North Korea (북한지역 수력발전댐 개발가능지점에 대한 연간가능발생전력량 분석 및 개발 우선순위 평가)

  • Kwon, Minsung;Kim, Tae-Woong;Ahn, Jaehyun
    • Journal of Korea Water Resources Association
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    • v.51 no.10
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    • pp.929-939
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    • 2018
  • In North Korea, hydropower which occupies about 63% of power generation is a major electric power source, and North Korea has many advantages in the geographical for developing hydroelectric power. In this study, Information on the basin and dam capacity for 33 potential development site of hydroelectric dam was analyzed using DEM, and potential annual power generation was estimated by applying results of long-term runoff simulation with MWSWAT model for recent 30-year. The potential annual power generation at 33 dam was estimated to be about 28% of the current hydroelectric power in North Korea. In addition, a priority of dam development in each province was assessed by estimating the scale of an industry and prospecting the population change in the future. And a priority for dam development within the province was estimated based on the dam capacity and the potential annual power generation. The priority of each province was ranked in order of Pyeongannamdo, Hamgyungnamdo, Hamgyungbukdo, Hwanghaebukdo, Pyeonganbukdo, Jagangdo, Ryanggangdo, Hwanghaenamdo, and Gangwondo. The results of this study can be used as an initial review data for advancing to hydropower development project in North Korea.

The Impact Assessment of Climate Change on Design Flood in Mihochen basin based on the Representative Concentration Pathway Climate Change Scenario (RCP 기후변화시나리오를 이용한 기후변화가 미호천 유역의 설계홍수량에 미치는 영향평가)

  • Kim, Byung Sik;Ha, Sung Ryong
    • Journal of Wetlands Research
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    • v.15 no.1
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    • pp.105-114
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    • 2013
  • Recently, Due to Climate change, extreme rainfall occurs frequently. In many preceding studies, Because of extreme hydrological events changes, it is expected that peak flood Magnitude and frequency of drainage infrastructures changes. However, at present, probability rainfall in the drainage facilities design is assumed to Stationary which are not effected from climate change and long-term fluctuation. In the future, flood control safety standard should be reconsidered about the valid viewpoint. In this paper, in order to assess impact of climate change on drainage system, Future climate change information has been extracted from RCP 8.5 Climate Change Scenario for IPCC AR5, then estimated the design rainfall for various durations at return periods. Finally, the design flood estimated through the HEC-HMS Model which is being widely used in the practices, estimated the effect of climate change on the Design Flood of Mihochen basin. The results suggested that the Design Flood increase by climate change. Due to this, the Flood risk of Mihochen basin can be identified to increase comparing the present status.

Validation of the Measure of Health Literacy for the Elderly (고령자의 건강정보이해능력(Health Literacy) 측정도구 타당화)

  • Chun, Heeran;Cho, Sung-il;Kim, Il-Ho
    • Korean Public Health Research
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    • v.44 no.4
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    • pp.99-109
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    • 2018
  • Objective : Health literacy (HL) is, defined as "the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions." Being old is one of the main risk factors with limited health literacy. This study aims to adapt Chew's health literacy scale into the Korean language and validate the scale for the use of the elderly. Methods : Data were drawn from the '2016 Seoul Survey on Elderly Health and Functional Assessment, which includes a total of 725 people aged 60 to 79. The sample was randomly divided into two groups for reliability and validity tests of the modified Chew's scale of 8 items. The Korean version of the questionnaire was developed by group translation, expert reviews, and forward-backward translation. Exploratory and confirmatory factor analyses were conducted to assess and validate the factor structure of the scale. Results : Results suggest the two-factor structure ("Understanding" and "Applying" of HL) with 8 items. Exploratory factor analyses of the first sample (n=400) revealed that the internal reliability of the scale was high (Cronbach's ${\alpha}=.904$). Principal axis factoring extracted two factors ("Understanding" and "Applying" of HL) and explained 78.3% of total variance (KMO=.872, Bartlett's ${\chi}^2=2431.3$, df=28, p<.001). Confirmatory factor analysis of the second sample (n=325) was performed and the two-factor model was supported (GFI=.960, CFI=.979, TLI=.969, RMSEA=0.075). Conclusions : This study provides evidence for adequate criterion and validity of the health literacy scale for the community dwelling elderly in Korea.

Development of Korean SPAR(Soil-Plant-Atmosphere-Research) System for Impact Assessment of Climate Changes and Environmental Stress (기후변화 및 환경스트레스 영향평가를 위한 한국형 SPAR(Soil-Plant-Atmosphere-Research) 시스템의 개발)

  • Sang, Wan-Gyu;Kim, Jun-Hwan;Shin, Pyong;Baek, Jae-Kyeong;Lee, Yun-Ho;Cho, Jung-Il;Seo, Myung-Chul
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.21 no.3
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    • pp.187-195
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    • 2019
  • The needs for precise diagnostics and farm management-decision aids have increased to reduce the risk of climate change and environmental stress. Crop simulation models have been widely used to search optimal solutions for effective cultural practices. However, limited knowledge on physiological responses to environmental variation would make it challenging to apply crop simulation models to a wide range of studies. Advanced research facilities would help investigation of plant response to the environment. In the present study, the sunlit controlled environment chambers, known as Korean SPAR (Soil-Plant-Atmosphere-Research) system, was developed by renovating existing SPAR system. The Korean SPAR system controls and monitors major environmental variables including atmospheric carbon dioxide concentration, temperature and soil moisture. Furthermore, plants are allowed to grow under natural sunlight. Key physiological and physical data such as canopy photosynthesis and respiration, canopy water and nutrient use over the whole growth period are also collected automatically. As a case study, it was shown that the Korean SPAR system would be useful for collection of data needed for understanding the growth and developmental processes of a crop, e.g., soybean. In addition, we have demonstrated that the canopy photosynthetic data of the Korean SPAR indicate the precise representation of physiological responses to environment variation. As a result, physical and physiological data obtained from the Korean SPAR are expected to be useful for development of an advanced crop simulation model minimizing errors and confounding factors that usually occur in field experiments.

A Study on the Flooding Risk Assessment of Energy Storage Facilities According to Climate Change (기후변화에 따른 에너지 저장시설 침수 위험성 평가에 관한 연구)

  • Ryu, Seong-Reul
    • Journal of the Society of Disaster Information
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    • v.18 no.1
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    • pp.10-18
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    • 2022
  • Purpose: For smooth performance of flood analysis due to heavy rain disasters at energy storage facilities in the Incheon area, field surveys, observational surveys, and pre-established reports and drawings were analyzed. Through the field survey, the characteristics of pipelines and rivers that have not been identified so far were investigated, and based on this, the input data of the SWMM model selected for inundation analysis was constructed. Method: In order to determine the critical duration through the probability flood analysis according to the calculation of the probability rainfall intensity by recurrence period and duration, it is necessary to calculate the probability rainfall intensity for an arbitrary duration by frequency, so the research results of the Ministry of Land, Transport and Maritime Affairs were utilized. Result: Based on this, the probability of rainfall by frequency and duration was extracted, the critical duration was determined through flood analysis, and the rainfall amount suggested in the disaster prevention performance target was applied to enable site safety review. Conclusion: The critical duration of the base was found to be a relatively short duration of 30 minutes due to the very gentle slope of the watershed. In general, if the critical duration is less than 30 minutes, even if flooding occurs, the scale of inundation is not large.