• Title/Summary/Keyword: Risk Processes

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Validation of Gamma Knife Perfexion Dose Profile Distribution by a Modified Variable Ellipsoid Modeling Technique

  • Hur, Beong Ik;Jin, Seong Jin;Kim, Gyeong Rip;Kwak, Jong Hyeok;Kim, Young Ha;Lee, Sang Weon;Sung, Soon Ki
    • Journal of Korean Neurosurgical Society
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    • v.64 no.1
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    • pp.13-22
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    • 2021
  • Objective : High precision and accuracy are expected in gamma knife radiosurgery treatment. Because of the requirement of clinically applying complex radiation and dose gradients together with a rapid radiation decline, a dedicated quality assurance program is required to maintain the radiation dosimetry and geometric accuracy and to reduce all associated risk factors. This study investigates the validity of Leksell Gamma plan (LGP)10.1.1 system of 5th generation Gamma Knife Perfexion as modified variable ellipsoid modeling technique (VEMT) method. Methods : To verify LGP10.1.1 system, we compare the treatment plan program system of the Gamma Knife Perfexion, that is, the LGP, with the calculated value of the proposed modified VEMT program. To verify a modified VEMT method, we compare the distributions of the dose of Gamma Knife Perfexion measured by Gafchromic EBT3 and EBT-XD films. For verification, the center of an 80 mm radius solid water phantom is placed in the center of all sectors positioned at 16 mm, 4 mm and 8 mm; that is, the dose distribution is similar to the method used in the x, y, and z directions by the VEMT. The dose distribution in the axial direction is compared and analyzed based on Full-Width-of-Half-Maximum (FWHM) evaluation. Results : The dose profile distribution was evaluated by FWHM, and it showed an average difference of 0.104 mm for the LGP value and 0.130 mm for the EBT-XD film. Conclusion : The modified VEMT yielded consistent results in the two processes. The use of the modified VEMT as a verification tool can enable the system to stably test and operate the Gamma Knife Perfexion treatment planning system.

Recent Research Trend in Microneedle Fabrication Using 3D Printing (3D 프린팅을 이용한 마이크로니들 제작의 최신 연구 동향)

  • Choo, Sangmin;Jung, Jae Hwan
    • Applied Chemistry for Engineering
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    • v.32 no.4
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    • pp.379-384
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    • 2021
  • A microneedle is a tool that used for drug delivery and diagnosis. Unlike general injections, the microneedle is short in length, enabling effective drug delivery while minimizing pain and risk of infection. Conventionally, microneedles have been manufactured precisely at a nanometer level based on microelectro mechanical systems (MEMS) technology, requiring expensive equipments & maintenance and complicated processes. To address the issues, 3D printing research has been conducted to fabricate microneedles simply, economically, and rapidly. Since 3D printing facilitates to manufacture prototypes and apply feedbacks, it is advantageous for the development and commercialization of microneedle for pharmaceuticals and cosmetics. Therefore, this review will introduce stereolithography (SLA), two-photon polymerization (2PP), dynamic light processing (DLP), continuous liquid interface production (CLIP), and fused deposition modeling (FDM) 3D printing technologies and also highlight research trends for microneedle production using them. Furthermore, the limitation of the current microneedle technology and the direction to be solved in the future will be discussed.

Proposal for Service Model for Internet Identity Management (인터넷 ID관리를 위한 서비스 모델 제안)

  • Song, Jung-Hwan;Kang, Yeon-Jung;Jang, Hwan-Seok
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.18 no.4
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    • pp.143-152
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    • 2008
  • The incredible progress of information and communication technology has allowed various information and communication services to emerge in the Web environment. Such a service is initiated when the user provides his/her personal information to the service provider and is then given an identifier and authentication data. A series of the processes is inconvenient as it requires authentication by the service provider each time that the user requests the service. Furthermore, as the user subscribes to more services, the volume of ID and authentication information increases. This compels the users to use an ID that is easy to remember or to register the same ID over and over, increasing the risk of ID hacking. It is clear that such threats will become more serious as our lives become more dependent upon the Internet and as the Internet service environment advances. With the introduction of different services, the need to efficiently manage ID has been raised. In this paper, a Internet Identity Management Service that enables the control of the flow of the user’s personal information, which is used and stored for the Internet service, is proposed from the user's perspective.

Smelting of Platinum Group Metals and Recycling of Spent Catalyst (백금족 금속의 제련과 폐촉매의 리사이클링)

  • Son, Injoon;Sohn, Ho-Sang
    • Resources Recycling
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    • v.30 no.3
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    • pp.18-29
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    • 2021
  • Platinum group metals (PGMs) are used in a wide range of application fields such as catalysts, electronic devices, electrodes, electrical devices, fuel cells and high temperature materials due to their excellent electrical and thermal conductivity as well as chemical resistivity. Platinum group elements are generally associated with nickel-copper sulfides in magmatic rocks. Depending on the relative concentrations of the PGMs, they are produced either as the primary products or as by-products of the nickel and copper. However, PGMs natural resource deposits are strictly limited in countries such as South Africa and Russia. The annual supply of PGMs is only under 500 t. Considering the limited supply of PGMs, there will be a noticeable increase in the supply risk associated with PGMs in the near future. Therefore, it is extremely important to recover PGMs from secondary resources such as spent catalysts. This paper reviews on overview of PGMs extraction and recycling processes.

Role of n-3 long-chain polyunsaturated fatty acids in human nutrition and health: review of recent studies and recommendations

  • Dael, Peter Van
    • Nutrition Research and Practice
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    • v.15 no.2
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    • pp.137-159
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    • 2021
  • Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to as n-3 LCPUFA. They have been extensively studied for their effects in human nutrition and health. This paper provides an overview on metabolism, sources, dietary intake, and status of n-3 LCPUFA. A summary of the dietary recommendations for n-3 LCPUFAs for different age groups as well as specific physiological conditions is provided. Evidence for n-3 LCPUFA in cardiovascular diseases, including new studies, is reviewed. Expert recommendations generally support a beneficial effect of n-3 LCPUFA on cardiovascular health and recommend a daily intake of 500 mg as DHA and EPA, or 1-2 servings of fish per week. The role of n-3 LCPUFA on brain health, in particular neurodegenerative disorders and depression, is reviewed. The evidence for beneficial effects of n-3 LCPUFA on neurodegenerative disorders is non-conclusive despite mechanistic support and observational data. Hence, no definite n-3 LCPUFA expert recommendations are made. Data for the beneficial effect of n-3 LCPUFA on depression are generally compelling. Expert recommendations have been established: 200-300 mg/day for depression; up to 1-2 g/day for major depressive disorder. Recent studies support a beneficial role of n-3 LCPUFAs in reducing the risk for premature birth, with a daily intake of 600-800 mg of DHA during pregnancy. Finally, international experts recently reviewed the scientific evidence on DHA and arachidonic acid (ARA) in infant nutrition and concluded that the totality of data support that infant and follow-on formulas should provide both DHA and ARA at levels similar to those in breast milk. In conclusion, the available scientific data support that dietary recommendations for n-3 LCPUFA should be established for the general population and for subjects with specific physiological conditions.

Academic Procrastination As A Challenge For Students' Mental Health In The Context Of Distance Learning And The Virtual World During The Covid-19 Pandemic

  • Stoliarchuk, Olesia;Khrypko, Svitlana;Olga, Dobrodum;Ishchuk, Olena;Kokhanova, Olena;Sorokina, Olena;Salata, Karina
    • International Journal of Computer Science & Network Security
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    • v.22 no.3
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    • pp.276-284
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    • 2022
  • The research aims to study the dynamics of academic procrastination and its impact on the mental health of students during the transition to distance learning during the COVID-19 pandemic. At the beginning of the COVID-19 pandemic, it was identified a declining tendency of overall rates of academic procrastination and at the same time increase in the number of carriers of mid and high levels of academic procrastination. The decline in the general rates of academic procrastination at the beginning of 2021 testifies to the adaptation processes experienced by students to the conditions of distance learning. It was documented that students' academic procrastination is accompanied by a steady negative emotional tension. During the transition to distance learning, the intensity of students' learning activity has increased, which altogether causes stress as one of the main reasons for the academic procrastination among future psychologists. The study identified a risk of academic procrastination manifestation among students for their mental health, which provides a basis for developing and testing a program to prevent the phenomenon of academic procrastination among degree-seeking students.

A Case Study on Product Production Process Optimization using Big Data Analysis: Focusing on the Quality Management of LCD Production (빅데이터 분석 적용을 통한 공정 최적화 사례연구: LCD 공정 품질분석을 중심으로)

  • Park, Jong Tae;Lee, Sang Kon
    • Journal of Information Technology Services
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    • v.21 no.2
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    • pp.97-107
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    • 2022
  • Recently, interest in smart factories is increasing. Investments to improve intelligence/automation are also being made continuously in manufacturing plants. Facility automation based on sensor data collection is now essential. In addition, we are operating our factories based on data generated in all areas of production, including production management, facility operation, and quality management, and an integrated standard information system. When producing LCD polarizer products, it is most important to link trace information between data generated by individual production processes. All systems involved in production must ensure that there is no data loss and data integrity is ensured. The large-capacity data collected from individual systems is composed of key values linked to each other. A real-time quality analysis processing system based on connected integrated system data is required. In this study, large-capacity data collection, storage, integration and loss prevention methods were presented for optimization of LCD polarizer production. The identification Risk model of inspection products can be added, and the applicable product model is designed to be continuously expanded. A quality inspection and analysis system that maximizes the yield rate was designed by using the final inspection image of the product using big data technology. In the case of products that are predefined as analysable products, it is designed to be verified with the big data knn analysis model, and individual analysis results are continuously applied to the actual production site to operate in a virtuous cycle structure. Production Optimization was performed by applying it to the currently produced LCD polarizer production line.

Effects of pain neuroscience education on kinesiophobia in patients with chronic pain: a systematic review and meta-analysis

  • Kim, Hyunjoong;Lee, Seungwon
    • Physical Therapy Rehabilitation Science
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    • v.9 no.4
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    • pp.309-317
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    • 2020
  • Objective: One of the treatment strategies for controlling chronic pain and preventing disability is patient education. Pain neuroscience education (PNE) has been proven to be effective in explaining the biological and physiological processes associated with pain experiences to patients. The purpose of this review is to investigate the effectiveness of PNE for kinesiophobia such as avoidance response in patients with chronic pain. Design: A systematic review and meta-analysis. Methods: MEDLINE, EMBASE, CINAHL, PEDro, and the Cochrane Central Register of controlled trials databases were searched through November 2020 and included a randomized controlled trials evaluating kinesiophobia in musculoskeletal patients with chronic pain. In 8 randomized controlled trial studies, 'Cochrane's risk of bias (RoB) tool was used for qualitative analysis, and results of post-intervention were analyzed through RevMan 5.4 for quantitative analysis. Results: For this review, 8 randomized controlled trials of 369 patients with chronic pain were selected for PNE. A systematic review and meta-analysis also included 8 randomized controlled trials. The effect on kinesiophobia was more effective than the control group (-0.86; 95% confidence interval [CI], -1.22 to -0.51; heterogeneity [χ2=21.18, df=7, I2=67%]; overall effect [Z=4.80]). In addition, the effect on pain was more effective than the control group (-0.53; 95% CI, -1.05 to -0.01; heterogeneity [χ2=47.42, df=7, I2=85%]; overall effect [Z=2.01]). Conclusions: The results of this review suggest that PNE and combined PNE have a positive effect on the improvement of pain and kinesiophobia in patients with chronic pain.

Integrated Ship Cybersecurity Management as a Part of Maritime Safety and Security System

  • Melnyk, Oleksiy;Onyshchenko, Svitlana;Pavlova, Nataliia;Kravchenko, Oleksandra;Borovyk, Svitlana
    • International Journal of Computer Science & Network Security
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    • v.22 no.3
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    • pp.135-140
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    • 2022
  • Scientific and technological progress is also fundamental to the evolving merchant shipping industry, both in terms of the size and speed of modern ships and in the level of their technical capabilities. While the freight performance of ships is growing, the number of crew on board is steadily decreasing, as more work processes are being automated through the implementation of information technologies, including ship management systems. Although there have been repeated appeals from international maritime organizations to focus on building effective maritime security defenses against cyber attacks, the problems have remained unresolved. Owners of shipping companies do not disclose information about cyberattack attempts or incidents against them due to fear of commercial losses or consequences, such as loss of image, customer and insurance claims, and investigations by independent international organizations and government agencies. Issues of cybersecurity of control systems in the world today have gained importance, due to the fact that existing threats concern not only the security of technical means and devices, but also issues of environmental safety and safety of life at sea. The article examines the implementation of cyber risk management in the shipping industry, providing recommendations for the safe ship operation and its systems in order to improve vulnerability to external threats related to cyberattacks, and to ensure the safety and security of such a technical object as a seagoing ship.

CONSTRUCTION FINANCING AND INDUSTRY DEVELOPMENT

  • Yat-Hung, Chiang
    • International conference on construction engineering and project management
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    • 2009.05a
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    • pp.962-969
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    • 2009
  • The market of building construction has been competitive in Hong Kong, perhaps as anywhere else in the world. The barrier to entry is low because there are relatively low requirements on the three factors of production - technology, manpower and finance. The prevailing building technology is traditional and labour-intensive. There is also not much need of capital because clients' periodic payments have been the main source of project finance. Further, capitalizing on trade sub-contracting, contractors have been able to keep their direct labour-force small and to transfer much of their business risk to the sub-contractors. Based on interviews to solicit the perception of a sample of building contractors on the particular issues of construction finance, we present the findings in this paper and discuss the various implications. We believe that the current practice of construction financing is both the cause and effect of the competition within, and the competitiveness of, the building construction sector in Hong Kong. We conclude that the building construction sector is "locked or stuck" in this "equilibrium" of traditional technology, reliance on clients' finance and exploitation of sub-contracting. In this "equilibrium" state, there is hardly any motivation for contractors to engage themselves in product or process innovation. Consequently, any talk of industry reform or innovation could only remain just that. We believe that this problem is not unique in Hong Kong. The building construction sector in many other developed and developing economies is posed with similar if not the same problems and constraints. We conclude that there has to be some "external forces" to bring this "equilibrium" state to a higher level "equilibrium" one where higher value-added building construction services are supplied and demanded. This is a state where building contractors possessing innovative technology, better financial and manpower resources could thrive to build better buildings with innovative building methods and processes.

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