• 산업진흥연구
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• 제8권4호
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• pp.29-36
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• 2023

본 연구는 산업재해를 예방하기 위하여 제조업 현장에서 위험성평가 시 위험 가중요인이 반영될 수 있도록 방법론을 제시하고 실제 제조업 사업장에 적용하여 실증하였다. 제조업에서 최근 10년간(2012~2021) 발생한 사고 242,906건 전체에 대하여 사례를 통계적으로 분석한 결과 6개월 미만의 신규 작업자, 외국인 작업자, 55세 이상의 고령 작업자 및 손과 팔이 위험구역에 노출되는 작업, 9시에서 12시 전까지 실시되는 비일상 작업은 유의성 있게 사고발생률이 높게 나타났다. 또한 표적집단면접(FGI)을 통하여 위험성 결정 단계에서 사고의 가능성 추정에 가중 값으로 적용하도록 하였다. 본 연구결과를 통하여 위험성평가 시 위험 가중요인을 정량적으로 반영할 수 있고 파악된 위험의 크기를 보다 근접하게 평가함으로써 사고를 예방하는데 그 의의가 있다.

• 한국환경보건학회지
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• 제39권1호
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• pp.32-42
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• 2013

Objectives: Cryptosporidium, a protozoan parasite, has been recognized as a frequent cause of waterborne disease due to its extremely strong resistance against chlorine disinfection. Although there has as yet been no report of a Cryptosporidium outbreak through drinking water in Korea, it is important to estimate the health risk of Cryptosporidium in water supply systems because of the various infection cases in human and domestic animals and frequent detection reports on their oocysts in water environments. Methods: This study evaluated the annual infection risk of Cryptosporidium in tap water using the quantitative microbial risk assessment technique. Exposure assessment was performed upon the results of a national survey on Cryptosporidium on the water sources of 97 large-scale water purification plants in Korea, water treatment efficacy, and daily unboiled tap water consumption. The estimates of the US Environmental Protection Agency on the mean likelihood of infection from ingesting one oocyst were applied for effect assessment. Results: Using probabilistic methods, mean annual infection risk of Cryptosporidiosis by the intake of tap water was estimated to fall within the range of $2.3{\times}10^{-4}$ to $1.0{\times}10^{-3}$ (median $5.7{\times}10^{-4}$). The risk in using river sources was predicted to be four times higher than with lake sources. With 0.5-log higher removal efficacy, the risk was estimated to be $1.8{\times}10^{-4}$, and could then be lowered by one-third. Conclusions: These estimations can be compared with acceptable risk and then used to determine the adequacy and priority of various drinking water quality strategies such as the establishment of new treatment technology.

• Toxicological Research
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• 제21권2호
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• pp.87-98
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• 2005

Human exposure to nano-sized particles (NSP) has increased over the last century with anthropogenic sources, and the rapid development of nanotechnology becomes an another source of such exposure. Information regarding the safety of nanotechnology and its product, nanoparticles, is urgently needed when assuming exposure through inhalation, oral intake, and penetration across skin is ever increasing as growing nanotechnology rapidly. The recent advancement of biokinetic studies with NSP and newer epidemiologic and toxicologic studies with ultrafine particles can be the basis for the nanotoxicology. Some concepts of nanotoxicology can be known from the results of these results. Specific small size of NSP, when inhaled, facilitates deposition by difusional mechanism in all regions of the respiratory tract and uptake into cells, ranscytosis across epithelial and endothelial cells into the blood and lymph circulation to reach target sites. Translocation along axons and dendrites of neuron makes an access to CNS and ganglia. These biokinetics are dependent on NSP surface chemistry. Risk assessments of NSP include appropriate and relevant doses/concentration selections, the increase effects in the organism and the benefits of possible desirable effects. An interdisciplinary team approach is desirable for nanotoxicology research and an appropriate risk assessment.

• 대한지역사회영양학회지
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• 제8권4호
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• pp.574-583
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• 2003

The purpose of this study was to investigate the anthropometry, biochemical parameters and electrolytes concentrations of the Total Parenteral Nutrition (TPN) patients according to their nutritional status at the time of admission. Thirty-three patients in the Intensive Care Unit at S University Hospital were the subjects of this study. Their nutritional status was classified as At-risk I (Mild PCM, n = 13), At - risk II (Moderate PCM, n = 9) and At-risk III (Marasmus + kwashiorkor + severe PCM, n = 11) . Anthropometeric, biochemical and dietary assessments were performed. The Patients intake of calories (75.02%) and protein (53.15%) was insufficient compare with Korean RDA requirements. The body weight and the Body Mass Index (BMI) in the At-risk III group were significantly lower than in the other groups. The percentage of body weight loss and change of body weight (kg) were significantly higher than in the other groups. The subjects were malnourished as indicated by nutritional related parameters such as serum total protein, albumin, total lymphocyte count (TLC), hemoglobin and hematocrit. Serum total protein, albumin and TLC levels were lower at the time of admission before TPN administration. But after TPN administration, they increased. The electrolyte concentrations did not show any differences following TPN administration. The nutritional status of the patients could be affect by the duration of TPN administration and the number of days of the patients hospitalization. The patients who require nutritional support need the continuous follow-up care and monitoring by a nutritional support team. (Korean J Community Nutrition 8(4) : 574-583, 2003)

• 대한조선학회논문집
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• 제55권2호
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• pp.93-102
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• 2018

Quantitative Risk Assessment (QRA) has been used in shipping and offshore industries for many years, supporting the decision-making process to guarantee safe running at different stages of design, fabrication and throughout service life. The assessments of a risk perspective are informed by the frequency of events (probability) and the associated consequences. As the number of offshore platforms increases, so does the length of subsea pipelines, thus there is a need to extend this approach and enable the subsea industry to place more emphasis on uncertainties. On-board operations can lead to objects being dropped on subsea pipelines, which can cause leaks and other pipeline damage. This study explains how to conduct hit frequency analyses of subsea pipelines, using historical data, and how to obtain a finite number of scenarios for the consequences analysis. An example study using probabilistic methods is used.

• Environmental Analysis Health and Toxicology
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• 제18권3호
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• pp.219-224
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• 2003

1,4-Dioxane is used as a solvent for lacquers, paints, varnish removers, dye baths and printing compositions. And it is also used for detergent preparations, cosmetics, deodorants and fumigants. A method is described for the determination of 1,4-dioxane in water samples by GC/MS. The extraction recoveries were studied for some solvents and solvent volume ratio were investigated using r-butyl methyl ether (MTBE). Optimum condition was obtained by the liquid-liquid extraction using the 10 mL of MTBE for 10 mL of water. Method detection limit of 1,4-dioxane in the 20 mL of water samples was 0.05 ng/mL. It could be determined in the range of 0.24∼240 ng/mL in treated water, and in the range of 0.69∼81.9 ng/mL in raw water, respectively. Risk assessments with 1,4-dioxane exposure by drinking water ingestion were carried out. Based on the results of analysis, chronic daily intake of 1,4-dioxane was 2.22${\times}$10$\^$-4/ mg/kg/day and excess cancer risk was calcu-lated to be 2.44${\times}$10$\^$-6/.

• 한국환경보건학회지
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• 제35권3호
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• pp.235-238
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• 2009

In Korea, talc that has been widely used for a lot of consumer products as well as industrial usage until recently was found to be contaminated with asbestos. It becomes a major social issue. Critical health risk about both talc and talc contaminated with asbestos was summarized through literature review. It has been confirmed that talc can pose ovarian cancer when talc powder is used in the genital area. International Agency for Research on Cancer (IARC) already concluded that the perineal use of cosmetic talc can cause possibly carcinogenic to humane(Group 2B), although there was study reporting the lack of a consistent an established correlation between perineal dusting frequency and ovarian tissue talc concentrations and the lack of a consistent dose-response relationship with ovarian cancer risk. The association between talc exposure and ovarian cancer is as strong as in recent studies. The epidemiological studies to date provided inadequate evidence for the carcinogenicity of either inhaled or ingested talc that does not contain asbestos or asbestosiform fibers. Future studies should focus on seeking evidence in talc-exposed populations, collecting reliable information on age at initial used of body powder, exposure assessments related to talc use and dose response relationship in order to identify possible risk of talc ingested or inhaled.

• 한국IT서비스학회지
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• 제7권1호
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• pp.117-130
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• 2008

Multi-attribute risk assessments provide a useful framework for systematic quantitative risk assessment that the security manager can use to prioritize security requirements and threats. In the first step, the security managers identify the four significant outcome attributes(lost revenue, lost productivity, lost customer, and recovery cost). Next. the security manager estimates the frequency and severity(three points estimates for outcome attribute values) for each threat and rank the outcome attributes according to AHP(Analytic Hierarchy Process). Finally, we generate the threat index by using muiti-attribute function and make sensitivity analysis with simulation package(Crystal Ball). In this paper, we show how multi-attribute risk analysis techniques from the field of security risk management can be used by security managers to prioritize their organization's threats and their security requirements, eventually they can derive threat index. This threat index can help security managers to decide whether their security investment is consistent with the expected risks. In addition, sensitivity analysis allows the security manager to explore the estimates to understand how they affect the selection.

• Nuclear Engineering and Technology
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• 제46권1호
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• pp.11-26
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• 2014

The analyses carried out within the Seismic Probabilistic Risk Assessments (SPRAs) of Nuclear Power Plants (NPPs) are affected by significant aleatory and epistemic uncertainties. These uncertainties have to be represented and quantified coherently with the data, information and knowledge available, to provide reasonable assurance that related decisions can be taken robustly and with confidence. The amount of data, information and knowledge available for seismic risk assessment is typically limited, so that the analysis must strongly rely on expert judgments. In this paper, a Dempster-Shafer Theory (DST) framework for handling uncertainties in NPP SPRAs is proposed and applied to an example case study. The main contributions of this paper are two: (i) applying the complete DST framework to SPRA models, showing how to build the Dempster-Shafer structures of the uncertainty parameters based on industry generic data, and (ii) embedding Bayesian updating based on plant specific data into the framework. The results of the application to a case study show that the approach is feasible and effective in (i) describing and jointly propagating aleatory and epistemic uncertainties in SPRA models and (ii) providing 'conservative' bounds on the safety quantities of interest (i.e. Core Damage Frequency, CDF) that reflect the (limited) state of knowledge of the experts about the system of interest.

• 국제초고층학회논문집
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• 제10권4호
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• pp.299-310
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• 2021

External fire spread has the potential to breach vertical compartmentation and violate the fire safety strategy of a building. The traditional design solution to this has been the use of non-combustible materials and spandrel panels but recent audits show that combustible materials are widespread and included in highly complex systems. Furthermore, most jurisdictions no longer require detailing of spandrel panels under many different circumstances. These buildings require rapid investigation using rational scientific methods to be able to adequately classify the fire risk. In this work, we use an extensive experimental campaign of material-scale data to explore the critical parameters driving upward flame spread. Two criteria are outlined using two different approaches. The first evaluates the time to ignition and the time to burnout to assess the ability for a fire to spread, and can be easily determined using traditional means. The second evaluates the preheated flame length as the critical parameter driving flame spread. A wide range of cladding materials are ranked according to these criteria to show their potential propensity to flame spread. From this, designers can use conservative approaches to perform fire risk assessments for buildings with combustible materials or can be used to aid decision-making. Precise estimates of flame spread rates within complex façade systems are not achievable with the current level of knowledge and will require a substantial amount of work to make progress.