• Toxicological Research
• /
• 제17권
• /
• pp.219-225
• /
• 2001

The basic structure for assessment of potential health risks from environmental chemicals is widely agreed upon, but many of the details of risk assessment procedures differ among practitioners. Government regulatory agencies typically have guidelines or standard procedures for their risk assessments, established to ensure consistency and comparability, to set standards for adequacy, and to embody underlying tenets. In setting and updating such guidelines, each agency takes into account not only the prevailing thinking about appropriate procedures, but also its own goals and responsibilities and the precedents it has set for itself in past analyses. This results in variations in methods, and consequently in characterization of risks, among regulatory assessments, even when they are based on the same data. As a result, adopting existing assessments from a variety of regulatory bodies needs to be done with caution. This paper examines some of the variants in risk assessment approaches among American federal regulatory agencies and relates them to the variations in regulatory responsibilities of those groups. Comparisons to international practices are also drawn. The impact on development of world-wide risk standards is discussed.

• 한국항해항만학회지
• /
• 제33권1호
• /
• pp.9-19
• /
• 2009

본 논문에서는 상선의 운항 사고에 관한 양적 위기평가에 관한 실험적인 접근방법들을 기술했다. 이 연구의 목적은 국제해사기구의 공식 안전성 평가(FSA)를 기반으로 운항 사고에 크게 기여하는 요소들을 분석하고, 양적 위기평가기법에 기반을 둔 운항 사고의 확률적인 위기수준을 평가한 후, 선박 안전을 저해할 수 있는 운항 사고 위기를 예측하는 것이다. 확률지수(PI)와 심각성지수(SI) 구성된 위기지수(RI)에 대한 운항 사고의 확률적인 위기수준은 베이지안 이론을 적용한 베이지안 네트워크를 기반으로 본 연구에서 제안한 운항사고 위기 모델을 이용해서 예측했다. 그리고 355건의 핵심 손상 사고기록으로 구성된 시나리오 그룹을 이용하여 제안한 모델의 적용 가능성을 평가하였다. 평가결과, 예측한 PI의 정답률 $r_{Acc}$은 82.8%로 나타났고, $S_p{\gg}1.0$과 $S_p{\ll}1.0$에 포함되는 PI 변수들의 민감도 초과비율은 10% 이내로 나타났으며, 예측한 SI의 평균 오차 $\bar{d_{SI}}$는 0.0195로 나타났고, 예측한 RI의 정답률은 91.8%로 나타났다. 이러한 결과는 제안한 모델과 방법이 실제 해상운송 현장에 적용 가능함을 나타낸다.

• Earthquakes and Structures
• /
• 제18권3호
• /
• pp.367-377
• /
• 2020

Incremental dynamic analysis (IDA) widely uses for the collapse risk assessment procedures of buildings. In this study, an IDA-based collapse risk assessment methodology is proposed, which employs a novel approach for detecting the near-collapse (NC) limit state. The proposed approach uses the modal pushover analysis results to calculate the maximum inter-story drift ratio of the structure. This value, which is used as the upper-bound limit in the IDA process, depends on the structural characteristics and global seismic responses of the structure. In this paper, steel midrise intermediate moment resisting frames (IMRFs) have selected as case studies, and their collapse risk parameters are evaluated by the suggested methodology. The composite action of a concrete floor slab and steel beams, and the interaction between the infill walls and the frames could change the collapse mechanism of the structure. In this study, the influences of the metal deck floor and autoclaved aerated concrete (AAC) masonry infill walls with uniform distribution are investigated on the seismic collapse risk of the IMRFs using the proposed methodology. The results demonstrate that the suggested modified IDA method can accurately discover the near-collapse limit state. Also, this method leads to much fewer steps and lower calculation costs rather than the current IDA method. Moreover, the results show that the concrete slab and the AAC infill walls can change the collapse parameters of the structure and should be considered in the analytical modeling and the collapse assessment process of the steel mid-rise intermediate moment resisting frames.

• 한국환경보건학회지
• /
• 제40권3호
• /
• pp.187-203
• /
• 2014

Objectives: As the demand to deal with pathogens in domestic research institutions has expanded and biological accidents have increased, the need for systematic biosafety management in infectious disease laboratories has grown. According to international standards, risk assessment (RA) is required for biosafety management. However, RA criteria have not been clearly established in Korea, so to this end I have attempted to determine RA criteria meeting international levels Methods: In order to provide RA criteria for application, I analyzed the RA criteria in use in the U.S., Europe and at international organizations. In order to ensure the public nature of the RA criteria, I constructed the research model through modified management consulting methodology reflecting the model of Radnor and O'Mahoney. Results: According to the results of the study, existing laboratory biosafety regulations were comparable to domestic laboratory safety laws. Existing laboratory biosafety standards that are designed around risk factors were found to be insufficient. An RA case to be carried out in infectious disease laboratories at the National Institute of Health of KCDC was identified. Conclusion: To establish a systematic risk management system meeting international standards, it was necessary first to harmonize the systems of national and international standards. In addition, in order to provide specific biosafety management on-site, I recognized a need for methodology and planning strategies to discover biosafety management so that it can be carried out as required through the RA of individual laboratories.

• 한국지하수토양환경학회지:지하수토양환경
• /
• 제10권5호
• /
• pp.1-10
• /
• 2005

본 연구에서는 토양오염지역의 위해성 평가에 관한 미국, 영국, 네덜란드, 독일, 덴마크의 정책을 비교 분석하였다. 이들 국기는 미국과 18개 유럽 국가들에 관한 유럽연합의 초기 분석 자료를 이용하여 선택하였다. 이로부터 도출한 시사점은 토양오염지역의 조사 및 관리를 위해 각 국가들은 위해성 평가를 이용하고 있으며, 토양질 기준을 정책수 단으로 위해성 평가와 병행하고 있는 것이다. 이러한 외국의 정책과 시사점을 고려할 때, 위해성 평가를 정책 수단으로 이용하고 있지 않은 우리나라에 대해 다음과 같은 정책 추진을 제언할 수 있다. 첫째, 국가적인 차원에서 이용 할 수 있는 합리적인 위해성 평가 방법의 마련이다. 둘째, 부지의 위해성 평가를 토양질의 기준과 연계시키는 것이다. 우리나라의 실정에 적합한 부지의 위해성 평가방법을 마련하기 위해서는 추가적인 자료의 분석을 통한 심층적인 연구가 필요하고, 사회 다양한 계층간의 논의 및 합의가 필요할 것이다. 토양오염으로 간주되는 토양질 기준을 초과하는 부지의 경우에 위해성 평가의 시행을 고려할 수 있을 것이다. 또한 위해성 평가는 오염물질의 자연함량이 일반적으로 다른 특정 지역, 예를 들면 광산지역 등에 대해 적용하는 것을 고려할 수 있을 것이다. 금번 연구의 결과는 토양 오염지역의 위해성 평가에 관해 우리가 시행해야 할 추가적인 연구 및 정책시뮬레이션의 실행 동기를 함께 제공하고 있는 것으로 우리나라의 토양오염지역을 조사, 복원, 해제에 따른 법, 제도 발전의 한 부문으로 사용될 수 있을 것이다.

• Environmental Analysis Health and Toxicology
• /
• 제17권4호
• /
• pp.347-355
• /
• 2002

As concerns on the effects of soil contamination on human health have grown, more efforts have been made to quantify the effects. One of such efforts is the development of risk assessment methodology. The fundamental objectives of this approach is to investigate the alternative options that reduce the risk of hazardous chemicals results from environmental pollution, which will eventually lead to an accomplishment of removement of identified toxicants in polluted environment. The U.S. EPA Risk Assessment guidance for the superfund (RAGS) provides a methods for assessing the health risk of contaminated soils and determining the preliminary remediation goals (PRGs). Using this approach, we assessed the health risk and preliminary remediation goals of petroleum contaminated site in Kyounggi province.

• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2006년도 추계학술대회
• /
• pp.34-45
• /
• 2006

Chemical toxicants are metabolically converted to numerous metabolites in the body. Toxicokinetic characteristics of metabolites could be therefore used as biomarker of exposure for human risk assessment. Biologically based dose response (BBDR) model was proposed for future direction of risk assessment. However, this area has not been developed well enough for human application. Benzo(a)pyrene (BP), for example, is a well-known environmental carcinogen and may produce more than 100 metabolites and BPDE-DNA adduct, a covalently bound form of DNA with benzo(a)pyrene diolepoxides (BPDES), has been applied to qualitatively or quantitaively estimate human exposure to BP. In addition, di(2-ethylhexyl) phthalate (DEHP), a widely used plasticize. in the polymer industry, is one of endocrine-disrupting chemicals (EDCs) and has been monitored in humans using urinary or serum concentrations of DEHP or its monomer MEHP for exposure and risk assessment. However, it is difficult to estimate the actual level of toxicants using these biomarkers in humans using. This presentation will discuss a methodology of exposure and risk assessment by application of metabolic profiling kinetics.

• 대한안전경영과학회지
• /
• 제14권3호
• /
• pp.151-158
• /
• 2012

The objective of this paper is to propose a method of how to perform risk assessment in the early stage of defense research and development for the acquisition of weapon systems. An advanced method for risk assessment and its associated objective functions are developed first based on the concept of systems engineering. The developed method is then applied to carry out the analysis of alternatives in the trade-off environments. As a case study, the multi-purpose training ship is considered, where it is performed using the notions of technology readiness levels, degrees of difficulty, and technology need values to facilitate design space visualization and decision maker interaction. It is noted that decision makers can benefit from our approach as an improved risk assessment method in the context of multi-criteria decision making.

• 대한인간공학회지
• /
• 제31권1호
• /
• pp.185-189
• /
• 2012

Objective: The aim of this paper is to introduces Hyundai Heavy Industry's ergonomic risk assessment tool, H-OWAS, which is considering work load and frequency compared to the OWAS. Background: As prevalence of work-related musculoskeletal disorders(WMSDs) in ship building industries has been much higher than that in other industries, most of the large scaled corporations have implemented their own prevention program since legislation on the prevention of WMSDs had introduced in 2003. Method: This paper introduces WMSDs prevention program, HEMP(HHI Ergonomics Management Program) which consists of risk assessment, improvement efforts of working environments, medical treatment and training/evaluation and describes how to operate the program. We also describe application of OWAS method considering work load and frequency for risk factor analysis(H-OWAS) and shows methodology for assessing the ergonomic risk factor. And comparison of the assessment results between OWAS and H-OWAS is carried out by statistical analysis. Result: There was statistically significant difference in the assessment results between OWAS and H-OWAS, and regression shows H-OWAS explains the borg's scale of perceived exertion more clearly than OWAS. Conclusion: H-OWAS has been proved more effective tool than OWAS to evaluate ergonomic risk factor under real working condition. Application: H-OWAS can be widely applied to the many other companies when implementing the ergonomics risk assessment.

• Coupled systems mechanics
• /
• 제11권6호
• /
• pp.505-524
• /
• 2022

Floods represent extreme hydrological phenomena that affect populations, environment, social, political, and ecological systems. After the catastrophic floods that have hit Europe and the World in recent decades, the flood problem has become more current. At the EU level, a legal framework has been put in place with the entry into force of Directive 2007/60/EC on Flood Risk Assessment and Management (Flood Directive). Two years after the entry into force of the Floods Directive, Bosnia and Herzegovina (B&H), has adopted a Regulation on the types and content of water protection plans, which takes key steps and activities under the Floods Directive. The "Methodology for developing flood hazard and risk maps" (Methodology) was developed for the territory of Bosnia and Herzegovina, following the methodology used in the majority of EU member states, but with certain modifications to the country's characteristics. Accordingly, activities for the preparation of the Preliminary Flood Risk Assessment for each river basin district were completed in 2015 for the territory of Bosnia and Herzegovina. Activities on the production of hazard maps and flood risk maps are in progress. The results of probable climate change impact model forecasts should be included in the preparation of the Flood Risk Management Plans, which is the subsequent phase of implementing the Flood Directive. By the foregoing, the paper will give an example of the development of the hydrodynamic model of the Zujevina River, as well as the development of hazard and risk maps. Hazard and risk maps have been prepared for medium probability floods of 1/100 as well as for high probability floods of 1/20. The results of LiDAR (Light Detection and Ranging) recording were used to create a digital terrain model (DMR). It was noticed that there are big differences between the flood maps obtained by recording LiDAR techniques in relation to the previous flood maps obtained using georeferenced topographic maps. Particular attention is given to explaining the Methodology applied in Bosnia and Herzegovina.