Background: Consumers and patients in the last two decades have increasingly turned to various internet search engines including Google for information. Google Trends records searches done using the Google search engine. Google Trends is free and provides data on search terms and related queries. One recent study found a large public interest in "dental anesthesia". In this paper, we further explore this interest in "dental anesthesia" and assess if any patterns emerge. Methods: In this study, Google Trends and the search term "dental pain" was used to record the consumer's interest over a five-year period. Additionally, using the search term "Dental anesthesia," a top ten related query list was generated. Queries are grouped into two sections, a "top" category and a "rising" category. We then added additional search term such as: wisdom tooth anesthesia, wisdom tooth general anesthesia, dental anesthetics, local anesthetic, dental numbing, anesthesia dentist, and dental pain. From the related queries generated from each search term, repeated themes were grouped together and ranked according to the total sum of their relative search frequency (RSF) values. Results: Over the five-year time period, Google Trends data show that there was a 1.5% increase in the search term "dental pain". Results of the related queries for dental anesthesia show that there seems to be a large public interest in how long local anesthetics last (Total RSF = 231) - even more so than potential side effects or toxicities (Total RSF = 83). Conclusion: Based on these results it is recommended that clinicians clearly advice their patients on how long local anesthetics last to better manage patient expectations.
The rising demand for carotenoids can be met by microbial biosynthesis as a promising alternative to chemical synthesis and plant extraction. Several species of lactic acid bacteria (LAB) specifically produce C30 carotenoids and offer the added probiotic benefit of improved gut health and protection against chronic conditions. In this study, the recently characterized Lactiplantibacillus plantarum subsp. plantarum KCCP11226T produced the rare C30 carotenoid, 4,4'-diaponeurosporene, and its yield was optimized for industrial production. The one-factor-at-a-time (OFAT) method was used to screen carbon and nitrogen sources, while the abiotic stresses of temperature, pH, and salinity, were evaluated for their effects on 4,4'-diaponeurosporene production. Lactose and beef extract were ideal for optimal carotenoid production at 25℃ incubation in pH 7.0 medium with no salt. The main factors influencing 4,4'-diaponeurosporene yields, namely lactose level, beef extract concentration and initial pH, were enhanced using the Box-Behnken design under response surface methodology (RSM). Compared to commercial MRS medium, there was a 3.3-fold increase in carotenoid production in the optimized conditions of 15% lactose, 8.3% beef extract and initial pH of 6.9, producing a 4,4'-diaponeurosporene concentration of 0.033 A470/ml. To substantiate upscaling for industrial application, the optimal aeration rate in a 5 L fermentor was 0.3 vvm. This resulted in a further 3.8-fold increase in 4,4'-diaponeurosporene production, with a concentration of 0.042 A470/ml, compared to the flask-scale cultivation in commercial MRS medium. The present work confirms the optimization and scale-up feasibility of enhanced 4,4'-diaponeurosporene production by L. plantarum subsp. plantarum KCCP11226T.
The Journal of the Convergence on Culture Technology
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v.7
no.2
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pp.351-357
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2021
At the time when interest in the use of big data is rising in the face of the technological paradigm shift of the 4th industrial revolution, interest in the use of patented big data is increasing, especially as the proportion of intangible assets of companies increases. In addition to quantitative information, patent data contains various information such as unstructured text such as title, abstract, claim, citation and citation relations, drawings, and technology classification. It is judged that the use of treatment is important. Therefore, in this study, in order to systematically operate the innovative patent strategy framework and to secure a competitive advantage by strengthening the fundamental technological competitiveness of the company, we propose a method of using patent big data centering on the case of Company A, and verify its validity. I would like to suggest some implications. Through this, it is intended to raise awareness of the use of patent big data, and to suggest ways to use patent big data in connection with the company's company-wide strategy, business strategy, and functional strategy.
The rising prices of landfills and the lack of cement production are motivating researchers to be more interested in using wastes to produce concrete mixtures materials. The use of waste materials such as eggshell and matakoline waste not only reduces landfill costs and space, but also reduces the cost of cement production for the concrete mixture. However, recycling waste materials has become critical in order to effectively manage environmental sustainability. The purpose of this paper is to investigate the appropriate properties of self-compacting concrete (SCC) by incorporating waste materials such as crushed ceramics as coarse aggregate and nano egg shell (NES) and nanoclay (NC) as cement replacements. Fresh properties of SCC, such as segregation, flow time and diameter, V-funnel, H2/H1 ratio, and fresh unit weight of concrete mixtures, as well as hardened properties, such as 7, 14, and 28 days compressive strength and 28 and 90 days flexural strength, were measured for this purpose. The presence of NC in the SCC mixture enhanced the compressive strength of the concrete when 5% of NES was added or in the case without the addition of NES compared to the control mixture. The flexural strength enhanced with the incorporation of NC in the SCC increased the flexural strength of the concrete compared to the control mixture, but the incorporation of 5% of NES decreased the flexural strength compared to the mixtures with NC. These results prove the possibility of using crushed ceramics as the coarse aggregate, and NES and NC as substitutes for 5, 7, and 10% of the cement in SCC, because the properties of such SCC in hardened and fresh states are satisfactory.
Purpose - The purpose of this study is to examine how Korea's macroeconomic factors, such as GDP, CPI, Export, Import, Unemployment rate and USD/KRW exchange rate, are affected by the oil price shocks. Design/methodology/approach - This study used monthly and quarterly time-series data of each variable for the period 1983 to 2022, consisting of two sub-periods, to employ Granger causality test and GARCH method in order to identify the role of the oil price movement in macroeconomic factors in Korea. Findings - Korea's currency rate to the US dollar is negatively correlated with the price change of crude oil while the GDP change is positively correlated with the price change of crude oil with strong relationship between Export and Import in particular. The exchange rate and GDP growth are believed to be not correlated with the oil price change for the pre-GFC period. According to the Granger causality test, the price change in crude oil has a causal impact on CPI, Export and Import while other factors are relatively slightly affected. Transmission effect from the oil price to Export is found and there also exists volatility spillover from oil price to economic variables under examination. Comparing two sub-periods, CPI and Export volatility responds negatively to shocks in the oil price for the pre-GFC period while volatility of CPI and Unemployment reacts positively to the oil price shocks for the post-GFC period. Research implications or Originality - The findings of this study could be helpful for both domestic and international investors to build their portfolio for the risk management since rising WTI price can be interpreted as a result of global economic growth and ensuing increase in the worldwide demand of the crude oil. Consequently, the national output is expected to increase and the currency is also expected to be strong in the long run.
Journal of The Korean Society of Integrative Medicine
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v.11
no.1
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pp.43-51
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2023
Purpose : This study suggests that the unique chakra arrangement of Tibetan singing bowls resembles the mantra of chakra lotus in the tantric tradition and the structure of chakra ascent, The two aim at the liberation of consciousness and confirm that they have a body, mind, and conscious healing mechanism. Methods : First, the structural characteristics of Tibetan singing bowls arrangement and chakra lotus mantra arrangement were investigated through the consideration of previous studies. Next, the healing mechanism of Tibetan singing bowls, which has been learned in Nepal, was examined through previous studies and literature to clarify that the rise of chakra in the two systems has a balance of body, mind, and consciousness and aims at liberation of consciousness. Results : The arrangement of Tibetan chakras is similar to the mantra of chakra lotus. Both have a structure in which the auxiliary sound of the previous chakra is interlocked with the structure of being the main sound of the next chakra to raise the chakra. At this time, the rise of the chakra is the liberation of consciousness by the ultimate purpose. Conclusion : Tibetan chakra are structurally similar to chakra lotus mantras and chakra ascents, as they have a theoretical background to tantric traditions. Chakra is the quality of inner consciousness that is conveyed to the outside and expressed in its own actions. Therefore, chakras should be well coordinated to lead our lives healthily. In this point, the chakra arrangement of Tibetan singing bowls is a system that exposes the inner balance to the outside and heals us more directly. Therefore, Tibetan singing bowls therapy has an integrated medical value in restoring our mind and body balance. Because chakras are dimensions of consciousness, the study of chakras is abstract or lacking, so more systematic and scientific study of chakras is needed.
The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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v.8
no.3
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pp.131-150
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1979
Recently only a few correlations between various factors due to the different grades of surface roughness for the nucleate pool boiling have been proposed. The main purpose of this work is to test the validity of these types of correlations between related factors to nucleate pool boiling phenomena. The boiling experiments using distilled water were carried out at the heat flux ranging from $7.4\times10^4\;to\;2.4\times10^5kcal/m^2h$ on the sintered porous metal surface with the cavity diameter of 10, n, 40, 70, $100{\mu}$, respectively, at the atmospheric pressure, To determine the bubble sizes, number of nucleation sites, delay and growth time, frequency of bubble emission and rising velocities of bubbles, the high speed motion picture technique was employed. In the correlation $f{\propto}D_b^n$, where f denotes frequency of bubble emission and $D_b$ departure diameter, n, the power factor of $D_b$, have been found to be from -2 to -10/3. The correlation C in the correlation between heat flux q and density of nucleation sites $\frac{N}{A}$, $q=C(\frac{N}{A})^n$, was appeared to be more crucial than the power factor n. The correlation of the heat flux q to the temperature difference ${\Delta}T$ and the density of nucleation sites$\frac{N}{A}$, was proposed to be $$q-460{\Delta}T^{\frac{5}{4}}=K{\Delta}T{\frac{5}{3}}(\frac{N}{A})^{\frac{2}{3}}$$. The values of heat transfer coefficient obtained in this experiments for the porous sintered metal surface appeared to be very high in comparison with the formerly obtained results for the other surfaces.
This study examines and identified a series of strategies of Russia's political elites to maintain and strengthen their dominance by reviewing the case of revisions in the election laws of Russia in 2014. At that time, a mixed-member electoral system was newly introduced, and on the surface, it seemed that the new system was a step toward meeting the demands of the people for "enhanced democracy". However, in 2016 and 2021, the ruling party of Russia won the general elections by making the most of the factors that could distort the election results inherent in the mixed-member electoral system. Therefore, this study aimed to analyze whether the revision of election laws was a mere vehicle used by the ruling party, United Russia, to maintain its political power, or whether it was a leap forward to achieve democracy. The study result indicate that the revision of election laws in 2014 was part of the policy responses to the internal conflicts in the circle of Russia's political elites, which had been rising since 2008, as well as to the public resistance. In other words, it was confirmed that the revision of election laws was one of the measures taken to "minimize competition" and "reproduce political power on a stable basis".
S. Arivazhagan;K.A. Naseer;K.A. Mahmoud;N.K. Libeesh;K.V. Arun Kumar;K.ChV. Naga Kumar;M.I. Sayyed;Mohammed S. Alqahtani;E. El Shiekh;Mayeen Uddin Khandaker
Nuclear Engineering and Technology
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v.55
no.9
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pp.3268-3276
/
2023
The practice of identifying the potential zones for mineral exploration in a speedy and low-cost method includes the use of satellite imagery analysis as a part of remote sensing techniques. It is challenging to explore the iron mineralization of a region through conventional methods which are a time-consuming process. The current study utilizes the Hyperion satellite imagery for mapping the iron mineralization and associated geological features in the Irikkur region, Kannur, Kerala. Along with the remote sensing results, the field study and laboratory-based analysis were conducted to retrieve the ground truth point and geochemical proportion to verify the iron ore mineralization. The MC simulation showed for shielding properties indicate an increase in the linear attenuation coefficient with raising the Fe2O3+SiO2 concentrations in the investigated rocks where it is varied at 0.662 MeV in the range 0.190 cm-1 - 0.222 cm-1 with rising the Fe2O3+SiO2 content from 57.86 wt% to 71.15 wt%. The analysis also revealed that when the γ-ray energy increased from 0.221 MeV to 2.506 MeV, sample 1 had the largest linear attenuation coefficient, ranging from 9.33 cm1 to 0.12 cm-1. Charnockite rocks were found to have exceptional shielding qualities, making them an excellent natural choice for radiation shielding applications.
Minor mergers leave behind long lived, but extremely faint and extended tidal features including tails, streams, loops and plumes. These act as a fossil record for the host galaxy's past interactions, allowing us to infer recent accretion histories and place constraints on the properties and nature of a galaxy's dark matter halo. However, shallow imaging or small homogeneous samples of past surveys have resulted in weak observational constraints on the role of galaxy mergers and interactions in galaxy assembly. The Rubin Observatory, which is optimised to deliver fast, wide field-of-view imaging, will enable deep and unbiased observations over the 18,000 square degrees of the Legacy Survey of Space and Time (LSST), resulting in samples of potentially of millions of objects undergoing tidal interactions. Using realistic mock images produced with state-of-the-art cosmological simulations we perform a comprehensive theoretical investigation of the extended diffuse light around galaxies and galaxy groups down to low stellar mass densities. We consider the nature, frequency and visibility of tidal features and debris across a range of environments and stellar masses as well as their reliability as an indicator of galaxy accretion histories. We consider how observational biases such as projection effects, the point-spread-function and survey depth may effect the proper characterisation and measurement of tidal features, finding that LSST will be capable of recovering much of the flux found in the outskirts of L* galaxies at redshifts beyond local volume. In our simulated sample, tidal features are ubiquitous In L* galaxies and remain common even at significantly lower masses (M*>10^10 Msun). The fraction of stellar mass found in tidal features increases towards higher masses, rising to 5-10% for the most massive objects in our sample (M*~10^11.5 Msun). Such objects frequently exhibit many distinct tidal features often with complex morphologies, becoming increasingly numerous with increased depth. The interpretation and characterisation of such features can vary significantly with orientation and imaging depth. Our findings demonstrate the importance of accounting for the biases that arise from projection effects and surface-brightness limits and suggest that, even after the LSST is complete, much of the discovery space in low surface-brightness Universe will remain to be explored.
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