• Journal of Haehwa Medicine
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• v.9 no.1
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• pp.215-223
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• 2000

To understand immunopharmacologic effects on Cervi Pantotrichum Cornu, Morindae Officinalis Radix, Cistanches Herba, Curculginis Rhizoma, Epimedii Herba, Eucommiae Cortex, we investigated chinese experimental documents, and we could reach conclusions as follows : 1. The effects on cell-mediated immune system were as follows. 1) The effects on macrophage (1) The herbal medicines promoting to increase the number of WBC in the peripheral blood were Morindae Officinalis Radix, Epimedii Herba and that promoting to reinforce the phagocytic functions of neutrophil was Curculginis Rhizoma. (2) The herbal medicines promoting the phagocytic functions of mononuclear, macrophage were Cervi Pantotrichum Cornu, Cistanches Herba, Eucommiae Cortex. 2) The herbal medicines stimulating the activities of T lymphocytes were Cervi Pantotrichum Cornu, Curculginis Rhizoma, Epimedii Herba, Eucommiae Cortex. 2. The effects on humoral immune system were as follows. 1) The herbal medicines increasing the activity of complement receptor were Cervi Pantotrichum Cornu, Curculginis Rhizoma. 2) The herbal medicines reinforcing immunity of spleen cells were Cervi Pantotrichum Cornu, Cistanches Herba, Epimedii Herba. 3) The herbal medicines promoting proliferation of spleen cells that produce antibody after having been immunized by SRBC were Cervi Pantotrichum Cornu, Cistanches Herba, Epimedii Herba. 3. The herbal medicines, reinforcing immunity on delayed type hypersensitivity were Cervi Pantotrichum Cornu, Cistanches Herba, Eucommiae Cortex. As you know in the many bibliological documents, the studies on the effects of Drugs for Tonifying Yang were started along right lines. Recently the studies on those were accomplished more rapidly and applied many immune diseases. We thought that Drugs for Tonifying Yang could be important immunopotentiators. Therefore we can apply those herbal medicines not only to immune diseases but also inflammatory diseases, senile infirmity and all sorts of tumor.

• The Journal of KAIRB
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• v.1 no.2
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• pp.30-42
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• 2019

In pharmaceutical clinical trials as human material research, the collection, use, storage and provision of human materials must be in accordance with the criteria stipulated in 「Bioethics and Safety Act」, except in the case that some criteria about it is in the law related to clinical trials such as 「Pharmaceutical Affairs Act」 and 「Enforcement Rule on Safety of Drugs, etc.」 so these take precedence over. Under 「Bioethics and Safety Act」, the core aspect of the legal standard for obtaining informed consent is the use of statutory form . The use of statutory form ensure that both those who obtain informed consent and those who give it can know the contents contained this form as well as recognize its importance. Thus, the person who has the right to informed consent can sign the statutory form after correct understanding of the contents. In reality, however, some researchers and IRB members determine that only the main informed consent form is to be used because most of contents on statutory from are included in the main informed consent form. Some other researchers and IRB members judge that the use of statutory form is not needed if human materials may only be used for laboratory testing and the rest will not be stored and provided for future use. Most of these determination and judgement is based on the interpretation of the Korea National Institute for Bioethics Policy(hereafter, KoNIBP) on IRB Information Portal Site. But, it is questionable whether the KoNIBP's interpretation is legally valid and the KoNIBP is the legal entity having authority to interpret existing statute. In some cased not only using the main informed consent form including enough information about the collection, use, storage and provision of human materials but also collecting necessary minimum human materials, and discarding the rest, unusing the statutory form may not cause the problem to respect and protect the research participant's rights. Therefore, the provision stipulating the criteria about the use of statutory form as the legal standard of obtaining informed consent that applies all human material research without exception should review to revise. At least, straighten out the confusion surrounding whether or not the statutory form is to be used, before the revision of related provision, considering the logical opinions of some researchers and IRB Members, the Ministry of Health and Welfare as the legal entity having authority to interpret existing statute should represent its opinion about permission of the acceptable exceptions.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.4
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• pp.200-204
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• 2006

Purpose: Determination of pulmonary to systemic blood flow ratio (QP/QS) is important for the management of patients with left-to-right shunt. This study was performed to assess the agreement of Qp/Qs ratio using the radionuclide method and oxymetry, to investigate the factors influencing the agreement, and to know how interchangeable the results of each technique. Materials and Methods: We compared the Qp/Qs measured by single-pass radionuclide angiocardiography and oxymetry during catheterization in 207 patients who underwent both studies. In radionuclide method, Qp/Qs was calculated from the pulmonary time-activity curves using a gamma variate fit. The correlation and Bland-Altman analysis were performed according to the levels of shunt and associated lesions. Results: The mean Qp/Qs was $1.83{\pm}0.50$ by radionuclide, and $1.74{\pm}0.51$ by oxymetry. The overall correlation coefficient was 0.86(p<0.001), and Bland-Altman range of agreement encompassing 4SD was 1.05. For atrial septal defect, ventricular septal defect, patent ductus arteriosus, tricuspid and mitral insufficiency, the correlation coefficient was 0.78, 0.90, 0.84, 0.63 and 0.44, and Bland-Altman range was 1.51, 0.74, 0.96, 1.57, and 1.50, respectively. Conclusion: There is good agreement but wide variance between the Qp/Qs ratios by radionuclide method and oxymetry. Associated atrioventricular valvar insufficiency decreases the correlation coefficient and widens the variance. Wide overall variance suggests that Qp/Qs measurements by two techniques should not be used interchangeably.

• Journal of Korean society of Dental Hygiene
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• v.16 no.4
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• pp.507-516
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• 2016

Objectives: The purpose of the study is to investigate the awareness and practice of dental unit waterline management in dental hygienist. Methods: A self-reported questionnaire was completed by 377 dental hygienists in Seoul and Gyeonggido from March 2 to April 30, 2015. The data were collected by direct visit and informed consent was received after explanation of the study. The questionnaire consisted of general characteristics of the subjects, awareness of dental waterline, practice of dental waterline, and implementation of dental waterline disinfection. Data were analyzed using SPSS 12.0 program. Results: There was a significant correlation between the dental unit waterline disinfection and the appropriateness of the water used for dental treatment(p<0.01, p<0.001). The handpiece was the most commonly used device before treatment and the majority of the subjects answered that they didn't take water out of ultrasonic scaler and air-water syringe on a daily basis. Conclusions: The majority of the dental hygienists did not know the right understanding and proper practice of dental unit waterline management. To reduce the dental device contamination, the continuing education of waterline management should be done for the dental hygienists.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.4
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• pp.105-112
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• 2017

PURPOSE: The purpose of this research was to know the effect of visual feedback self exercise (VFSE) on postural control in stroke patients. METHODS: 26 CVA patients were participated. The experimental group (EG) 12 (46.2%) and the control group (CG) 14 (53.8%), 17 males and 9 females. The subjects preformed VFSE on training instrument 10 minutes for 20 times in 2-3 weeks. The test was done 3 times. RESULTS: There were no statistically significant differences of the general characteristics of subjects between EG and CG by sex, affected site, muscle tone, sensory deficit, unilateral neglects, and vestibular dysfunction. The postural control effects of VFSE, in the EG showed that there were statistically significant differences among the tests during VFSE. However in the CG there were no statistically significant differences among the tests during VFSE. Also there was statistically significant difference between EG and CG after VFSE (p<.05). On the right hemiplegic EG showed that there was statistically significant difference between premid test and pre-post test after VFSE. But, the left hemiplegic EG showed that there was no statistically significant difference between before and after VFSE with all of tests. CONCLUSION: CVA patients had significant different of body weight ratio between hemiplegic side and the other side. This research suggested that CVA patients need self exercise with visual feedback for the improvement postural control ability. Therefore Physical therapist should not only prescribe hand-on exercise but also need to teach them self sensory feedback exercise to help them improve their postural control.

• Journal of Internet Computing and Services
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• v.3 no.4
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• pp.95-102
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• 2002

A continuous development of new hardware and operating systems brings the importance of portable programming, which can be imported into multi-platform environment. Also, the recent development of computer communication technology brings us many choices of accessing into the other platforms, which also becomes a burden for the programmers who should consider developing software fitting into diverse platforms The present GNU system tools creates a part of the source code automatically, and suggests a direction towards a new platform. but the source code must be prepared by the programmer at the source level. In this paper, we describe design and implementation of on interactive tool for developing multi-platform software, The tool is designed to help a programmer to build a portable program for multi-platform, even though the programmer does not know very well about various UNIX platforms, And, the tool uses existing GNU system tools, such as autoconf, autoheader, automake and etc, and is able to insert a portable code into a right position by interacting with a programmer.

• Korean Journal of Adult Nursing
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• v.19 no.4
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• pp.556-566
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• 2007

Purpose: This study attempted to analyze problems of informed consent in the clinical setting and appraise ethical aspects inherent in such issues in order to boost awareness of informed consent and its implementation among healthcare professionals. Methods: Study methods included identifying ethical meanings of informed consent in the clinical setting based on the principal ethics, and exploring the process of informed consent utilizing communicative ethics and feminine care ethics Results: The ethical basis of informed consent encompasses not only respect for autonomy but also prohibiting malice, practicing beneficience, and establishing justice. These principles, however, are limited in illustrating the ethical aspects of communicative ethics and care ethics that are entailed in informed consent within clinical settings. The ethical meaning of informed consent involves a communicative and caring process between healthcare professionals, patients, and family built on mutual respect. Conclusion: Healthcare professionals must fully understand the ethical meanings of informed consent and in turn respect and protect the clients' right to know and making decisions. Nurses especially, must take on the role of mediator and advocate throughout the process of obtaining informed consent, and practice ethical caring by facilitating communication grounded in mutual understanding among the physician, patient, and family members.

• Journal of Korean Philosophical Society
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• v.144
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• pp.33-50
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• 2017

Confucianism acts as the representative of Chinese mainstream cultures. Its research on the relation between groups and individuals, and about norms of the system is not only complete but of a long history. And its abundant management thoughts are important assets for us to know traditional culture and construct the management study of local colors. Menzi and Xunzi both inherit Confucianism but evolve into two Confucian paths of different scenarios. Both of them are different despite sameness, and are the same despite differences. Both are artistic all right, but have their imitation. This article aims to use Mengzi thoughts and Xunzi thoughts as a study domain. The study includes five sections. The first section as an introduction presents problems. The second section uses extrinsic factors to research the birth ground of Menzi, Xunzi management thoughts. The third section examines its basic presumptions in terms of inner logic. The fifth section analyzes its logical structure, and in this section the previous sections are concluded, presenting the possible development and relative limitations of Mengzi, Xunzi management thoughts. It is expected that we can re-examine traditional Confucius thoughts from the angle of management, renewing Confucius thoughts constantly in different ages.

• Journal of Korean society of Dental Hygiene
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• v.8 no.1
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• pp.23-35
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• 2008

I got the following conclusion that analyzes the dental health recognition, attitude and the action of the students who major in health section executing questionnaire about dental health behaviors from March 3 through 26 with health-related university students in some area in order to arrange the fundamental data that manage their mouth health rationally by using the investigation and comparison by sex and department in dental health teaching. The results obtained were as follows : 1. A large number of students recognized dental health as an important problem, but they believed that the level of their knowledges on dental health was not so high and female students were more negative than male students with regards to their own dental health condition. 2. 49.8% of the students know about tap water fluoridation program control business and 60.7% agreed and boy's approval rate was higher than girl's. But 42.2% of the not-related buccal department's students have a reservation about tap water fluoridation program control business. 3. Average brushing number of the boy is 51.0% 2 times a day according to sex, A girl appeared highest by 48.3% 3 times a day and there was statistically significantly different according to (pE0.01). there wasn't statistically significantly different according to department. Also, the period of the brushing was the most right after a breakfast, in the order of before sleep and after dinner. 4. Whether they go to the dentist's or not, 90.8% of them say 'yes', the result showed statistically significant difference according to sex (pE0.01), but It didn't show statistically significant difference according to department. Also, the purpose for visiting the dentist's office lately was the most caries treatment. and there was statistically significantly different according to sex (pE0.01), but there was not statistically significantly different according to department. 5. Oral health education-related subject approval's rate when the education course open is 65.0% there was statistically significantly different according to department (pE0.01). Also when oral health education-related subject as the liberal arts open' the rate of taking a course application showed 50.2% high appear. there was statistically significantly different according to department(pE0.01).

• The Korean Journal of Physiology
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• v.17 no.2
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• pp.177-182
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• 1983

In order to clarify the effect of the unilateral pneumonectomy on the compensatory growth of the residual lung, liver and kidney, and serum electrophoresis pattern, right lung pneumonectomy was performed on rabbits under general anesthesia with pentobarbital sodium. On the fifth day after the surgery, the weight of the residual lung, liver and bilateral kidneys was measured and organ weight-body weight ratio was calculated. And in an attempt to know whether the cells in the liver and the kidney were proliferated by unilateral pneumonectomy, DNA content was determined. The quantity(g/100 ml) of serum protein was determined also and serum electrophoresis was performed on cellulose acetate membrane. The results obtained are summarized as following. The weight of the residual lung and lung weight-body weight ratio was significantly increased respectively. The weight of the liver and organ weight-body weight ratio were not changed but the DNA content of the liver and kidney tissue increased significantly, illustrating that unilateral pneumonectomy caused cellular hyperplasia in the liver and in the kidney as well as in the residual lung. The quantity(g/100 ml) of serum protein was significantly increased and in the analysis of the electrophoregram, there was significant difference between the normal and pneumonectomy group. Taken together, these results indicate that unilateral pneumonectomy caused the compensatory hyperplasia of the liver, the kidney and the residual lung as well as the change of electro-phoretic pattern. And it also suggests that a humoral factor, which proliferates the cells in the residual lung, the liver and the kidney, existed in the pneumonectomized rabbits.