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Role of the Vestibular and Medullary Reticular Neuclei for the Motor Evoked Potentials in Rats (흰쥐의 운동유발전위에 대한 전정신경핵과 연수망상핵의 역할)

  • Lee, Moon-Young;Lee, Sung-Ho;Kim, Jae-Hyo;Park, Byung-Rim;Kim, Min-Sun
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.6
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    • pp.603-611
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    • 1997
  • The motor evoked potentials (MEPs) have been advocated as a method of monitoring the integrity of spinal efferent pathways in various injury models of the central nervous system. However, there were many disputes about origin sites of MEPs generated by transcranial electrical stimulation. The purpose of present study was to investigate the effect of major extrapyramidal motor nuclei such as lateral vestibular nucleus (VN) and medullary reticular nucleus (mRTN) on any components of the MEPs in adult Sprague-Dalwey rats. MEPs were evoked by electrical stimulation of the right sensorimotor cortex through a stainless steel screw with 0.5mm in diameter, and recorded epidurally at T9 - T10 spinal cord levels by using a pair of teflon-coated stainless steel wire electrodes with 1mm exposed tip. In order to inject lidocaine and make a lesion, insulated long dental needle with noninsulated tips were placed stareotoxically in VN and mRTN. Lidocaine of $2{\sim}3\;{\mu}l$ was injected into either VN or mRTN. The normal MEPs were composed of typical four reproducible waves; P1, P2, P3, P4. The first wave (P1) was shown at a mean latency of 1.2 ms, corresponding to a conduction velocity of 67.5 m/sec. The latencies of MEPs were shortened and the amplitudes were increased as stimulus intensity was increased. The amplitudes of P1 and P2 were more decreased among 4 waves of MEPs after lidocaine microinjection into mRTN. Especially, the amplitude of P1 was decreased by 50% after lidocaine microinjection into bilateral mRTN. On the other hand, lidocaine microinjection into VN reduced the amplitudes of P3 and P4 than other MEP waves. However, the latencies of MEPs were not changed by lidocaine microinjection into either VN or mRTN. These results suggest that the vestibular and reticular nuclei contribute to partially different role in generation of MEPs elicited by transcranial electrical stimulation.

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Application of HACCP System on Establishing Hygienic Standards in Pizza Specialty Restaurant - Focused on Salad Items - (HACCP제도를 활용한 피자 전문 패스트푸드 업체의 자체 위생관리기준 설정 - 샐러드를 중심으로 -)

  • Lee Bog-Hieu;Kim In-Ho;Huh Kyoung-Sook;Cho Kyong-Dong
    • Journal of the Korean Home Economics Association
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    • v.41 no.10 s.188
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    • pp.101-116
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    • 2003
  • The study was conducted to establish hygienic standards of salad items for pizza restaurant located in Seoul by applying HACCP system during the summer of 2000. The study measured temperature, time, pH, Aw and microbial assessments. The hygienic conditions of the kitchen and workers were on the average(1.21, 1.0 out of 3 pts.), but some improvement should be made: separate use of trash can and leftover disposal, separate use of knives and cutting boards, habits for hand washing and wearing hygienic gloves. For salad production, all procedures were peformed under food safety danger zone ($5{\~}60^{\circ}C$). The ingredients were mostly above pH 5.0 and high in Aw($0.94{\~}0.99$). Microbial assessments for salad production revealed that TPC($1.8{\times}10^3{\~}1.0{\times}10^{10}CFU/g$) and coliforms($1.5{\times}10{\~}5.2{\times}10^5 CFU/g$) exceeded the standards by Solberg et al.(TPC: $10^6CFU/g$, coliforms: $10^3CFU/g$). S. aureus was not detected but Salmonella was found in three food items(egg, macaroni and macaroni salad). Moreover, the workers' hands contained 3.1 104 CFU/g of TPC and 4.2 102 CFU/g of S. aureus requiring further remedy since it exceeded the safety standards suggested by Harrigan and McCance (500 CFU/g of TPC per $100cm^2$ and 10 CFU/g of coliforms per $100cm^2$). According to the critical control point(CCP) decision tree analysis, vegetable receiving, vegetable holding, mixing, display on coleslaw, macaroni draining, display on macaroni salad, egg peeling & cutting, apple cutting, and display on salad bar were determined as CCPs. From the findings it would be suggested that purchase of Quality materials, short holding and display time, storing food at right temperature, using sanitary cooking utensils, and improvement of workers' food handing practices are needed to ensure the safe salad production in this specific pizza restaurant.

The Effect of a Weighted Vest in Behavioral Problem for the Sensory Modulation Disorder (감각조절장애 아동의 문제행동에 무게감 있는 조끼 착용이 미치는 영향)

  • Han, Mi-Yea;Kim, Ji-Youn;Chang, Ki-Yeon;Park, Mi-Jin
    • The Journal of Korean Academy of Sensory Integration
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    • v.8 no.1
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    • pp.1-13
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    • 2010
  • Purpose : The purpose of the study is to find out the effect of wearing a weighted vest for sensory modulation disorder children. Methods : The participant of the study was an elementary school student, male, aged 7. The ABA single case study was used to design the study which was performed for 14 sessions. During the mediation period(B), the participant received the study cognitive education wearing weighted vest weighing 1.3kg. Results : Abnormal behaviors such as suddenly standing up from the chair, shaking body front and back, and left and right, sucking his thumb and putting the back of his hand to his mouth showed tendency to decrease gradually. Discussion : The participant's abnormal behaviors decreased as the sessions went by, which means the sensory integration therapy can improve the behavior of the child suffering the sensory modulation disorder. The design of the study had certain limitation to explain the influence a weighted vest to sustain the effect of the sensory integration therapy. New study design is needed for the extended studies to prove the lasting effect of a weighted vest for the sensory integration therapy and to suggest protocols incorporating wearing know-hows, proper wearing time, and the weight of a weighted vest.

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Effect of Mulberry Extract Complex on Degenerative Arthritis In Vivo Models (In Vivo 실험모델에서 오디추출복합물의 퇴행성관절염 개선 효능 연구)

  • Li, Hua;Yun, Sat-Byul;Shin, So Hee;Jeong, Jong-Moon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.5
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    • pp.634-641
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    • 2016
  • The objective of this research was to investigate the in vivo effects of treatment with mulberry extract complex (MEC) on cartilage degeneration and pain severity in an experimental model of rat degenerative arthritis. Monosodium iodoacetate ($2mg/50{\mu}L$) was injected into right knee joints of rats, followed by administration of MEC for 8 weeks at 400 mg/kg or 800 mg/kg of body weight. The experimental data show that treatment with MEC inhibited degradation of glycosaminoglycan and collagen in cartilage. On the other hand, concentrations of cartilage oligomeric matrix protein, C-terminal telopeptide-2, matrix metalloproteinase (MMP)-2, MMP-9, and MMP-13 in serum decreased in comparison with the control. The MEC at all dose levels could inhibit formation of xylene-induced ear edema. In this study, MEC demonstrated significant anti-arthritis activity, which is required for improvement of degenerative arthritis. Based on these results, MEC may be employed for the development of new health foods to ease symptoms of degenerative arthritis.

New Method of Computing the Stokes Drift Including Shear Effect in the Cross-Sectional Flow Field (유수단면 흐름장에서 Shear 효과를 갖는 Stokes Drift의 계산법)

  • Kim, Jong-Hwa;Park, Byong-Su
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.33 no.1
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    • pp.9-26
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    • 1997
  • Stokes drift(SD) and Lagrangian discharge(LD) are important factors for analysis of flushing time, tidal exchange, solute transport and pollutant dispersion. The factors should be calculated using the approached method to flow phenomena. The aim of this paper re-examines the previous procedures for computing the SD and LD, and is to propose the new method approached to stratified flow field in the cross-section of coastal region, e.g. Masan Bay. The intensity of velocity near the bottom boundary layer(BBL) depends on the sea-bed irregularity in the coastal estuaries. So we calculated the depth mean velocity(DMV) considering that of BBL omitted in Kjerfve's calculation method. It revealed that BBL effect resulting in application of the bay acts largely on DMV in half more among 1l stations. The new expression of SD and LD per unit width in the cross-section using the developed DMV and proposed decomposition procedure of current were derived as follow : $$Q=u_0+\frac{1}{2}H_1{U_1cos(\varphi_h-\varphi_u)+U_3cos(\varphi_h-\varphi{ud})} LD ED SD$(Q_{skim}+Q_{sk2}) The third term, $Q_{sk2}$, on the right-hand of the equation is showed newly and arise from vertical oscillatory shear. According to the results applied in 3 cross-sections including 11 stations of the bay, the volume difference between proposed and previous SD was founded to be almost 2 times more at some stations. But their mean transport volumes over all stations are 18% less than the previous SD. Among two terms of SD, the flux of second term, $Q_{skim}$, is larger than third term, $Q_{sk2}$, in the main channel of cross-section, so that $Q_{skim}$ has a strong dependence on the tidal pumping, whereas third term is larger than second in the marginal channel. It means that $Q_{sk2}$ has trapping or shear effect more than tidal pumping phenomena. Maximum range of the fluctuation in LD is 40% as compared with the previous equations, but mean range of it is showed 11% at all stations, namely, small change. It mean that two components of SD interact as compensating flow. Therefore, the computation of SD and LD depend on decomposition procedure of velocity component in obtaining the volume transport of temporal and spacial flow through channels. The calculation of SD and LD proposed here can separate the shear effect from the previous SD component, so can be applied to non-uniform flow condition of cross-section, namely, baroclinic flow field.

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The Pathology of Infection in the Department of Radiology (영상의학과 검사실의 감염 실태)

  • Shin, Seong-Gyu;Lee, Hyo-Yeong
    • Journal of radiological science and technology
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    • v.35 no.3
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    • pp.211-218
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    • 2012
  • This study was performed to understand the bacteriologic contamination level of radiological equipments which have frequent contacts with patients in the Department of Radiology of an university hospital in Busan area. Before sterilizing in-patient of the radiology rooms, MRSA, VRE, acinetobacter baumannii, candida albicans, and enterococcus sp. were detected. After sterilization, all the bacteria were not found. As examine times become longer, more bacteria were detected and after 7 hours, bacillus sp.(GPR), CNS, acinetobacter baumannii, and Enterococcus sp. were detected. After examining infected patients, bacillus sp.(GPR), VRE, enterococcus sp. CNS, and micrococcus sp. were detected and on the hands of radiological technologists, CNS, enterococcus sp. escherichia coli, and enterobacter sp. were detected. Similar species of bacteria were detected from each radiology room, but pseudomonas aeruginosa was detected on the handles of portable radiological equipments and the chair in the waiting room. Therefore, it is the most important to regularly sterilize radiological equipments and devices which have frequent contacts with patients and to sterilize them right after the use of infected patients in order to prevent the spread of infection. Also, thorough hand washing, education on infection and management for the characteristics of Department of Radiology should be performed for the systematic prevention of infection.

Clinical Comparison of Complications Between Esophagogastrostomy and Jejunal Free Transfer After Resection of Thoracic Esophageal Cancer (흉부식도암 절제술 후 식도-위 문합술군과 유리공장이식술군간의 조기 합병증 비교)

  • 신호승;이재진;홍기우
    • Journal of Chest Surgery
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    • v.34 no.11
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    • pp.843-847
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    • 2001
  • Background: Replacement of the esophagus remains a challenge for surgeons involved in esophageal disease. From 1996 to 1999, a total of 27 patients with esophageal cancer underwent free jejunal transfer(12cases) or esophagogastrostomy(15cases). To determine the results such as leakage of anastomosis site, stenosis, reflux esophagitis and operation time, respiratory complications, etc. we reviewed the 4 years experiences. Material and method: Palliative bypass surgery or esophageal prosthesis and cancers of the pharyngoesophageal or esophagogastric junction were excluded in this study. Resection was usually peformed through right thoracotomy and anastomosis was made with EEA staplers in esophagogas-trstomy. In cases of jejunal free transfer, 6cases of proximal esophagojejunostomy were stapled anastomosed and remaining 6 cases and all distal site were hand-sewn anastomosed. All reconstruction was done through posteromediastinal route. Result: There were two mortalities from thoracic esophagogastrostomy and one from jeunal free transfer. Major and minor complications(anastomosis site leakage: 3 cases, graft failure: 2cases etc) occurred in 27 cases. In 15 thoracic esophagogastrostomy cases, 11 patients had mild to moderate reflux esophagitis and 5 patients incurred stricture of the anastomosis. Operation time was about 550$\pm$280 minutes in jejunal free transfer, and about 300$\pm$ 160 minutes in esophagogastromy patients. Conclusion: Post operative reflux esophagitis and dysphagia were more frequent in Ivor-Lewis operation group than jejunal free transfer group; however, respiratory complications and operation time were significantly longer in jejunal (roe transfer group(p<0.05). To minimize the incidence of postoperative reflux esophagitis and dysphagia, patient evaluation focused on jejunal free transfer surgery is better than esophagogastrostomy followed by adequate post operative care.

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A Study on Stroke Extraction for Handwritten Korean Character Recognition (필기체 한글 문자 인식을 위한 획 추출에 관한 연구)

  • Choi, Young-Kyoo;Rhee, Sang-Burm
    • The KIPS Transactions:PartB
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    • v.9B no.3
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    • pp.375-382
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    • 2002
  • Handwritten character recognition is classified into on-line handwritten character recognition and off-line handwritten character recognition. On-line handwritten character recognition has made a remarkable outcome compared to off-line hacdwritten character recognition. This method can acquire the dynamic written information such as the writing order and the position of a stroke by means of pen-based electronic input device such as a tablet board. On the contrary, Any dynamic information can not be acquired in off-line handwritten character recognition since there are extreme overlapping between consonants and vowels, and heavily noisy images between strokes, which change the recognition performance with the result of the preprocessing. This paper proposes a method that effectively extracts the stroke including dynamic information of characters for off-line Korean handwritten character recognition. First of all, this method makes improvement and binarization of input handwritten character image as preprocessing procedure using watershed algorithm. The next procedure is extraction of skeleton by using the transformed Lu and Wang's thinning: algorithm, and segment pixel array is extracted by abstracting the feature point of the characters. Then, the vectorization is executed with a maximum permission error method. In the case that a few strokes are bound in a segment, a segment pixel array is divided with two or more segment vectors. In order to reconstruct the extracted segment vector with a complete stroke, the directional component of the vector is mortified by using right-hand writing coordinate system. With combination of segment vectors which are adjacent and can be combined, the reconstruction of complete stroke is made out which is suitable for character recognition. As experimentation, it is verified that the proposed method is suitable for handwritten Korean character recognition.

A Study on the Health Conditions of Male and Female Environmental Workers in Seoul (서울시 남$\cdot$여 환경미화원의 건강실태에 관한 고찰)

  • Kwon Young Eun;Suh Gil Hee;Kim Kyu-Sung;Choy Haeng-Gi;Jung Moon-Hee
    • Journal of Korean Public Health Nursing
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    • v.7 no.1
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    • pp.67-79
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    • 1993
  • This study was designed to identify the general health conditions and high risk factors of the male & female environmental workers. Thereby. the results of this study were to provide useful data as a contribution to knowledge for health protection and promotion. The data used for this study were environmental workers' physical examination cards; the male environmental workers were 52 persons. and the female environmental workers 52 persons. The data were analyzed by descriptive statistics, t-test, Pearson correlation, and distinction analysis, using the SPSS program. The results of this study can be summarized as follows; 1. Thers was a significant statistical difference between the two groups as to height. eyesight. serum GPT, hematocrit. The variables having little difference between two groups were weight. systolic blood pressure. total cholesterol. creatinine. 2. The rate of revealed in significant health examination was extra-health discrimination rate $28.8\%$, significant result of illness rate $12.5\%$. injury-inflicting rate $7\%$. second-time urine test $5.7\%$. antigen positive 3.8%. hearing impairment $2.8\%$, urine protein positive $1.9\%$. and urine sugar positive $1.9%$. 3. The workers diagnosed as extra-health discrimination were 30 persons or $28.8\%$. There was a difference between two groups on the prevalence. In the male environmental workers. ten times live problems and six times pulmonary tuberculosis and three times circulatory problems were revealed the higher than thoes of the female environmental workers. 4. In the male environmental workers, the relationship between age and systolic blood pressure revealed a significant correlation (r=0.22. p<0.05). In the female environmental workers. there was a negative correlation between age and weight (r= 0.25, p<0.05). the relationship between age and total cholesterol correlated positively (r=0.30, p<'0.05). 5. In the male environmental workers, there was a negative correlation between working career and creatinine(r=-0. 22, p<0.05) In the female environmental workers, there was a positive correlation between working career and total cholesterol (r= 0.58, p<0.01). 6. There were significant differences on working career and creatinine accdording to the male and female environmental workers who had any problems through x-ray inspection. 7. There were significant differences on height. eyesight. serum GPT according to the male and female environmental workers who were diagnosed as extra-health discrimination. 8. The female environmental workers who were diagnosed as 'care' were positively correlated with weight (r= 0.26. p<0.05)' and systolic blood pressure (r= 0.30. p<0. 05). on the other hand. the left and right eyesight correlated nagatively(r=-0.15. r=-0.33. p<0.01). 9. The most influential variables on the male and female environmental workers' health condition were working career, height. and weight. And these three variables could help determine the two groups at the level of 81. 8 percentage.

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Evaluation of PPG signals regarding to video attributes of smart-phone camera (스마트폰 카메라의 영상 속성에 따른 맥파 신호 평가)

  • Lee, Haena;Kim, Minhee;Whang, MinCheol;Kim, Dong Keun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.4
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    • pp.917-924
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    • 2015
  • In this study, we study that the video attributes captured by built-in camera in smart-phone can effect on the quality of PPG signal. The conditions of video attributes were composed of the bitrate, the resolution, the flash. As each condition, we measured a change in the red value of the video image and calculated a PPI(Pulse to Pulse Interval) for extracting the pulse wave signal. 20 subjects participated in the experiment and this experiment was carried out 18 tasks. The PPG signal was measured simultaneously for two minutes with the PPG sensor in the middle finger and Smart-phone in the forefinger of the right hand. By proceeding the correlation analysis, we obtained the highest correlation condition(83%, p=0.01), which the resolution was $640{\times}480$, bitrate was 5000kbps, flash was on. As a result, this study will be a useful guide for quality of signals in the pulse signal measurement system using built-in camera in smart-phone.