• Cross-Cultural Studies
• /
• v.22
• /
• pp.51-72
• /
• 2011

The economic decline coincided with the crooked political path of Spanish monarchy that has been on an almost permanent state of war. The Spanish empire was divided and consequently, general impoverishment spread throughout the whole country quickly. Nevertheless Spanish culture reached the climax, especially in the field of painting. Spanish paintings of 17th century are basically religious based on concept of Baroque, whose theme is usually the immaculate conception or mysterious figures of saints. Velaquez, Mrillo, and Ribera are the main painters who represented the trend of this time. Despite having fame as religious court painters, they painted subjects from low society such as beggars in rags, dwarves, jesters, or the poor child. They reflected an optimistic expression and an awe for human being in their paintings greatly. In this paper, we are dealing with three main representative painters of Baroque era whose theme was a picaresque character. This character was one of the axes that coexisted with royals and nobles in 17th century of Spain. The art works that are dealt in this paper serve as materials for historial values and through them we can observe the atmosphere of decline that dominated Spain of the time.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.21 no.6
• /
• pp.527-545
• /
• 2021

The aim of this systematic review was to determine the success rate of nitrous oxide-oxygen procedural sedation (NOIS) in dentistry. A systematic digital search was conducted for publications or reports of randomized controlled trials evaluating the clinical performance of NOIS. Abstracts of research papers were screened for suitability, and full-text articles were obtained for those who met the inclusion and exclusion criteria accordingly. The quality of the studies was assessed using the revised Cochrane risk-of-bias tool (RoB 2). A total of 19 articles (eight randomized clinical trials with parallel intervention groups and 11 crossover trials), published between May 1988 and August 2019, were finally selected for this review. The studies followed 1293 patients reporting NOIS success rates, with a cumulative mean value of 94.9% (95% CI: 88.8-98.9%). Thirteen trials were conducted on pediatric populations (1098 patients), and the remaining six were conducted on adults (195 patients), with cumulative efficacy rates of 91.9% (95% CI: 82.5-98.1%) and 99.9% (95% CI: 97.7-100.0%), respectively. The difference was statistically significant (P = 0.002). Completion of treatment and Section IV of the Houpt scale were the most used efficacy criteria. Within the limitations of this systematic review, the present study provides important information on the efficacy rate of NOIS. However, further well-designed and well-documented clinical trials are required and there is a need to develop guidelines for standardization of criteria and definition of success in procedural sedation. Currently, completion of treatment is the most used parameter in clinical practice, though many others also do exist at the same time. To maximize NOIS efficacy, clinicians should strictly consider appropriate indications for the procedure.