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The Shelf-life of Agricultural Organic Materials Containing Cinnamon or Derris Extract: Thermal Stability of Cinnamyl Derivatives and Rotenoids (계피 또는 데리스 추출물을 주원료로 하는 유기농업자재의 약효 성분 안정성)

  • Choi, Geun-Hyoung;Jin, Cho-Long;Park, Byung-Jun;Lim, Sung-Jin;Rho, Jin-Ho;Moon, Byung-Cheol;Kong, Seung-Heon;Kim, Jin Hyo
    • The Korean Journal of Pesticide Science
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    • v.20 no.3
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    • pp.197-202
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    • 2016
  • The stabilities of bioactive compounds in cinnamon or derris extract were investigated in commercial agricultural organic materials (biopesticide) during storage on different temperature conditions ($0^{\circ}C$, $23^{\circ}C$, $35^{\circ}C$, $45^{\circ}C$, and $54^{\circ}C$). The selected bioactive compounds were cinnamaldehyde, and cinnamyl alchol in cinnamon extract and deguelin, and rotenone in derris extract. Half-lives of the total cinnamyl derivatives in biopesticide (A, B, C, and D) ranged from 15.1 to 46.2 days on the different temperature and cinnamaldehyde was more stable than cinnamyl alcohol in the biopesticide. The half-lives of total rotenoid ranged from 1.7 to 173 days on the different temperature in the tested biopesticide (E, F, and G) containing derris extract. The stabilities of deguelin, and rotenon in the biopesticide showed similar values in the same condition.

A Study on Introduction and Activation Plan of P2P Car Sharing -For the Apartment Complex in Seoul- (P2P 카셰어링 도입 및 활성화 방안 연구 -서울시 아파트 단지를 대상으로-)

  • Jang, Jun-Seok;Rho, Jeong-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.47-60
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    • 2017
  • Car sharing, which is considered as a good example of innovation in the transportation sector, is a type of use in which a plurality of people share a single vehicle for a short period of time. It is divided into various types, NFP (Not For Profit) operated by a non-profit organization, B2C (Business to Customer), which is operated by a company, and Peer to Peer (P2P), which is directly connected to an individual. Among them, P2P car sharing is a method of sharing personal vehicles owned by individuals. It has the merit of reducing traffic congestion and providing for efficient traffic demand management by reducing the purchase rate of additional vehicles and minimizing the number of idle ones. This study examines the introduction of P2P car sharing in order to develop a traffic demand management policy and facilitate the transition to a sustainable transportation system. The spatial extent of the study consisted of apartment complexes in Seoul. In apartment complexes, it is possible to minimize the level of expenditure, such as operating expenses, by utilizing the APT management office and there is no difficulty in securing the necessary parking space. Therefore, apartment complexes were selected as the spatial range.

Gene Expression Profile of the Responder vs. the Non-Responder to the Acupuncture Mediated Analgesic Effects (침자극에 대한 반응과 비반응군 흰쥐의 특이 유전자 발현 연구)

  • Sur Young Chan;Rho Sam Woong;Lee Gi Seog;Ko Eun Jung;Hong Moo Chang;Shin Min Kyu;Min Byung il;Bae Hyun Su
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.3
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    • pp.633-642
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    • 2003
  • A pain is the symptom which defends against noxious stimulus about a human body, it is known that if the periphery of perceptive nerve were stimulated by a physical or chemical factors, the stimulation is induced by transmission to pain center in the cerebral cortex according to pain conduction tract. The treatment of pain is to decrease a stimulus that causes a pain or block off a nerve transmitting a stimulus or puts on a way to calm down pain center, but It is for adjustment of a pain to be the most representative in acupuncture among various ways to cure a pain in Oriental medicine. However, the analgesic effect of an individual response to acupuncture stimulation shows marked individual variations, so these days genetic a few approach is attempted. On this the author determined that the responding group was appointed those whose tail flick latency (TFL) responding time delayed the minimum of 30 % comparing with basal reaction time. For those whose TFL time had shorter than 30 % was grouped as a non-responding group. And then the hypothalamus of each group was dissected and RNA was further purified. After synthesizing cDNA using oligo dT primer, products were finally applied to the PCR. The results were as follows; The ratio of responding group to non-responding group was 6:4. Ach T (acetylcholinesterase T subunit), BF-I (Brain factor-I), DBH (Dopamine β-hydroxylase) and PNM (Phosphotidylethanolamine N-Methyltransferase) were revealed significantly in the responding group. Cathepsin B and Tau were revealed significantly in the non-responding group. The PCR results show that Ach T, BF-I, DBH and PNM are expressed abundantly in the responding group, where as cathepsin B and tau are abundant in the non-responding group. These results suggest that the analgesic effect on acupuncture stimulation is related to regulation of neurotransmitter as well as neurodegeration of cerebrum.

Development of UAV Flight Control Software using Model-Based Development(MBD) Technology (모델기반 개발기술을 적용한 무인항공기 비행제어 소프트웨어 개발)

  • Moon, Jung-Ho;Shin, Sung-Sik;Choi, Seung-Kie;Cho, Shin-Je;Rho, Eun-Jung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.38 no.12
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    • pp.1217-1222
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    • 2010
  • This paper describes the Model-Based Development(MBD) process behind the flight control software of a close-range unmanned aerial vehicle(KUS-9). An integrated development environment was created using a commercial tool(MATLAB $Simulink^{(R)}$), which was utilized to design models for linear/nonlinear simulation, flight control law, operational logic and HILS(Hardware In the Loop Simulation) system. Software requirements were validated through flight simulations and peer reviews during the design process, whereas the models were verified through the application of a DO-178B verification tool. The integrity of automatically generated C code was verified by using a separate S/W testing tool. The finished software product was embedded on two different types of hardware and real-time operating system(uC/OS-II, VxWorks) to perform HILS and flight tests. The key findings of this study are that MBD Technology enables the development of a reusable and an extensible software product and auto-code generation technology allows the production of a highly reliable flight control software under a compressed time schedule.

Effect of Sodium Hydroxide plus Hydrogen Peroxide Treated Mustard (Brassica campestris) Straw Based Diets on Rumen Degradation Kinetics (In sacco), Fermentation Pattern and Nutrient Utilization in Sheep

  • Mishra, A.S.;Misra, A.K.;Tripathi, M.K.;Santra, A.;Prasad, R.;Jakhmola, R.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.3
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    • pp.355-365
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    • 2004
  • Two experiments were conducted to determine the effect of alkaline hydrogen peroxide (AHP) treatment (1% NaOH+1.5% $H_2O_2$; 1 AHPMS, 2% NaOH+1.5% $H_2O_2$; 2AHPMS) on rate and extent of degradation of mustard straw (MS) in sacco in sheep, and its in vivo digestion and ruminal fermentation characteristics when fed to sheep with concentrate (200 g per sheep daily). The treatment of straw with 1 and 2% AHP increased its sodium content by 148 and 296% to that of untreated straw (UMS). There was significant decrease in NDF and hemicellulose contents of AHP treated straw and increase in cellulose and lignin contents. Phenolic acids like ferrulic, $\rho$-coumaric and o-coumaric significantly (p<0.001) reduced by AHP treatment of mustard straw. In first experiment the in sacco degradation of DM, OM and NDF was significantly (p<0.01) greater for 2 AHPMS than for UMS at all incubation periods. The disappearance of nutrient from 1 AHPMS and 2 AHPMS treated straws continue to increase up to 96 h whereas in UMS the peak disappearance was found at 48 h. By using the equation {(y=a+b) ($1-e^{-ct}$)} the degradation rates (c) for DM, OM, and NDF were significantly higher for UMS than AHP treated straws. Level of alkali (1 and 2%) had significant effect on degradation characteristics (a, b, c and $P_{0.05}$) of DM and NDF fraction of MS. However, the effect was not pronounced on OM fraction of MS. In feeding experiment, the intake of nutrients for DM, OM, cell wall constituents and energy was higher on 2 AHPMS, whereas no effect on the digestibility of these nutrients was observed. The apparent nitrogen retention was higher (p<0.05) both in 1 and 2 AHPMS groups. Water intake by animals was significantly increased due to AHP treated mustard straw feeding. Rumen liquor pH was higher in 2 AHPMS fed animals. The $NH_3-N$ of rumen liquor was not affected by feeding of AHP treated MS based diets. Total VFA concentration was significantly (p<0.01) higher in UMS fed group. The fractional out flow rate of DM was higher (p<0.05) in animals fed on 2 AHPMS diets compared to UMS and lAHPMS fed groups. The population of large holotrichs was higher (p<0.05) on AHP treated MS fed diets compared to UMS. The study indicated that treatment of mustard straw with AHP changed its chemical composition towards a better feed. The nutritive value of 2% AHP treated mustard straw was better in terms of dry matter intake and apparent nitrogen retention. The higher in sacco DM, OM and NDF disappearance however, was not confirmed by in vivo data in this study.

CT Radiologic Findings in Patients with Tuberculous Destroyed Lung and Correlation with Lung Function (결핵성 파괴폐의 흉부 전산화단층촬영 소견 및 폐기능과의 상관관계)

  • Chae, Jin-Nyeong;Jung, Chi-Young;Shim, Sang-Woo;Rho, Byung-Hak;Jeon, Young-June
    • Tuberculosis and Respiratory Diseases
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    • v.71 no.3
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    • pp.202-209
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    • 2011
  • Background: A tuberculous destroyed lung is sequelae of pulmonary tuberculosis and causes various respiratory symptoms and pulmonary dysfunction. The patients with a tuberculous destroyed lung account for a significant portion of those with chronic lung disease in Korea. However, few reports can be found in the literature. We investigated the computed tomography (CT) findings in a tuberculous destroyed lung and the correlation with lung function. Methods: A retrospective analysis was carried out for 44 patients who were diagnosed with a tuberculous destroyed lung at the Keimyung University Dongsan Hospital between January 2004 and December 2009. Results: A chest CT scan showed various thoracic sequelae of tuberculosis. In lung parenchymal lesions, there were cicatrization atelectasis in 37 cases (84.1%) and emphysema in 13 cases. Bronchiectasis (n=39, 88.6%) was most commonly found in airway lesions. The mean number of destroyed bronchopulmonary segments was 7.7 (range, 4~14). The most common injured segment was the apicoposterior segment of the left upper lobe (n=36, 81.8%). In the pulmonary function test, obstructive ventilatory defects were observed in 31 cases (70.5%), followed by a mixed (n=7) and restrictive ventilatory defect (n=5). The number of destroyed bronchopulmonary segments showed a significant negative correlation with forced vital capacity (FVC), % predicted (r=-0.379, p=0.001) and forced expiratory volume in one second ($FEV_1$), % predicted (r=-0.349, p=0.020). After adjustment for age and smoking status (pack-years), the number of destroyed segments also showed a significant negative correlation with FVC, % predicted (B=-0.070, p=0.014) and $FEV_1$, % predicted (B=-0.050, p=0.022). Conclusion: Tuberculous destroyed lungs commonly showed obstructive ventilatory defects, possibly due to bronchiectasis and emphysema. There was negative correlation between the extent of destruction and lung function.

Synthesis, Crystal Structure and Theoretical Calculation of a Novel Nickel(II) Complex with Dibromotyrosine and 1,10-Phenanthroline

  • Huang, Guimei;Zhang, Xia;Fan, Yuhua;Bi, Caifeng;Yan, Xingchen;Zhang, Zhongyu;Zhang, Nan
    • Bulletin of the Korean Chemical Society
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    • v.34 no.10
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    • pp.2889-2894
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    • 2013
  • A new complex [$Ni(phen)(C_9H_8Br_2NO_3)_2{\cdot}2CH_3OH{\cdot}2H_2O$] [phen: 1,10-phenanthroline $C_9H_8Br_2NO_3$: 3,5-dibromo-L-tyrosine] was synthesized and characterized by IR, elemental analysis and single crystal X-ray diffraction. X-ray crystallography shows that Ni(II) ion is six-coordinated. The Ni(II) ion coordinates with four nitrogen atoms and two oxygen atoms from three ligands, forming a mononuclear Ni(II) complex. The crystal crystallizes in the Orthorhombic system, space group $P2_12_12$ with a = 12.9546 ${\AA}$, b = 14.9822 ${\AA}$, c = 9.9705 ${\AA}$, V = 1935.2 ${\AA}$, Z = 1, F(000) = 1008, S = 0.969, ${\rho}_{calcd}=1.742g{\cdot}cm^{-3}$, ${\mu}=4.688mm^{-1}$, $R_1$ = 0.0529 and $wR_2$ = 0.0738 for 3424 observed reflections (I > $2{\sigma}(I)$). Theoretical study of the title complex was carried out by density functional theory (DFT) method and the B3LYP method employing the $6-3l+G^*$ basis set. The energy gap between HOMO and LUMO indicates that this complex is prone to interact with DNA. CCDC: 908041.

Identification and Characterization of Entomopathogenic Fungi Isolated from Bemisia tabaci in Korea (담배가루이(Bemisia tabaci )에서 분리한 곤충병원성진균의 동정 및 병원성 검정)

  • Park, Hyun-Rho;Ryu, Young-Hyun;Yeon, Il-Kyen;Nam, Sung-Hee;Kim, Dong-Geun;Han, Myung-Sae
    • Korean journal of applied entomology
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    • v.53 no.1
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    • pp.27-34
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    • 2014
  • Entomopathogenic fungi were isolated from Bemisia tabaci in an Oriental melon field, and their growth characteristics, factors related to a natural outbreak, and infectivity against Bemisia tabaci, Tetranychus urticae, and Frankliniella intonsa were investigated. The isolates had erect conidiophores bearing whorls of 4-6 phialides with a swollen base where cylindrical conidia of $3.0-3.4{\mu}m$ were attached. The isolates were identified as Isaria fumosorosea on the basis of morphological characteristics and an ITS sequence with 99% similarity. I. fumosorosea IFs-08 grew well on Sabouraud dextrose agar+yeast extract medium(3.2 mm/day/$24^{\circ}C$); it grew better at $35^{\circ}C$ than at $15^{\circ}C$. The isolates of I. fumosorosea-IFs were highly infective and killed 93.9-96.7% B. tabaci, 84.9-92.0% T. urticae, and 81.5-84.4% F. intonsa in bioassay, whereas three isolates (Isaria tenuipes, Isaria farinosa, and Isaria fumosorosea) from KACC showed a low infectivity of 10-20%. To the best of our knowledge, this is the first report of I. fumosorosea isolated from B. tabaci in Korea.

Study on Operation Method of Wcological Learning Facility for Wetland (대구광역시 달성습지 생태학습관 운영방안 연구)

  • Kim, Kwon;Eum, Jeong-Hee;Rho, Paikho
    • Korean Journal of Environment and Ecology
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    • v.32 no.3
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    • pp.332-341
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    • 2018
  • This study aims to establish operating methods for value-oriented and competitive operation of Dalseong Wetland Ecological Learning Center in Daegu, Korea, which will open in 2018. For this purpose, we surveyed 77 Ecological learning facility managers nationwide using 22 questions on the subjects such as the operating method, volunteer, budget, and profit. The managers of 50 ecological learning facilities (Type A) responded, and we extracted the responses by the managers of 12 ecological learning facilities (Type B) that had the similar size as the Dalseong Wetland Ecological Learning Center and conducted an additional analysis. The results of the survey indicated that it was advisable for Daegu Metropolitan City to operate the Dalseong Wetland Ecological Learning Center and that the staff at least 3-5 managers were necessary while the number of volunteers to regularly work at the center was estimated to be 25-30. Excluding labor costs, the annual operating budget was estimated to be between 150 million won and 200 million won if Daegu Metropolitan City operates the facility directly. This study is meaningful in that it provides reference data to establish realistic and detailed management plan of the Dalseong Wetland Ecological Learning Center based on the opinions of the surveyed managers of ecological learning facilities in Korea.

The Immuno-Modulatory and Antitumor Effects of Crude Polysaccharides Extracted from Tremella fuciformis (흰목이(Tremella fuciformis)에서 추출한 조다당류의 면역 활성 및 항암 효과)

  • Oh, Yun-Hee;Kim, Sang-Beom;Lee, Gun-Woo;Kim, Hye-Young;Shim, Mi-Ja;Rho, Hyun-Su;Lee, Hyun-Sook;Lee, Min-Woong;Lee, U-Youn;Lee, Tae-Soo
    • The Korean Journal of Mycology
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    • v.34 no.2
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    • pp.105-111
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    • 2006
  • Tremella fuciformis, one of edible and medicinal mushroom belonging to Tremellaceae of Basidiomycota, has been known to have a curative effect on sarcoma 180 of mice and lowering high blood pressure of human beings. Neutral salt soluble [0.9% NaCl (Fr. NaCl)], hot water soluble (Fr. HW) and methanol soluble (Fr. MeOH) substances were extracted from Tremella fuciformis. In vitro cytotoxicity tests, Fr. HW and Fr. NaCl were not cytotoxic against cancer cell lines such as NIH3T3, Sarcoma 180, and HT-29 at the concentration of $2000{\mu}g/ml$, while Fr. MeOH was cytotoxic to NIH3T3 and Sarcoma 180. Intraperitoneal injection with Fr. NaCl showed antitumor effect with life prolongation of 53% in mice inoculated with Sarcoma 180. Fr. NaCl improved the immunopotentiation activity of B lymphocyte by increasing the alkaline phosphatase activity by $3.0{\sim}8.1$ folds, respectively. Intraperitoneal injection with Fr. NaCl increased the numbers of peritoneal exudated cells and circulating leukocytes by 7.4 folds and 1.6 folds, respectively, than in the control group. The antitumor effect of T. fuciformis against Sarcoma 180 of mice was likely due to immunopotentiation activity.