• Title/Summary/Keyword: RhoA

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A central limit theorem for sojourn time of strongly dependent 2-dimensional gaussian process

  • Jeon, Tae-Il
    • Journal of the Korean Mathematical Society
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    • v.32 no.4
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    • pp.725-737
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    • 1995
  • Let $X_t = (X_t^(1), X_t^(2))', t \geqslant 0$, be a real stationary 2-dimensional Gaussian process with $EX_t^(1) = EX_t^(2) = 0$ and $$ EX_0 X'_t = (_{\rho(t) r(t)}^{r(t) \rho(t)}), $$ where $r(t) \sim $\mid$t$\mid$^-\alpha, 0 < \alpha < 1/2, \rho(t) = o(r(t)) as t \to \infty, r(0) = 1, and \rho(0) = \rho (0 \leqslant \rho < 1)$. For $t > 0, u > 0, and \upsilon > 0, let L_t (u, \upsilon)$ be the time spent by $X_s, 0 \leqslant s \leqslant t$, above the level $(u, \upsilon)$.

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HYPERSURFACES WITH PRESCRIBED MEAN CURVATURE IN MEASURE METRIC SPACE

  • Zhengmao Chen
    • Bulletin of the Korean Mathematical Society
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    • v.60 no.4
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    • pp.1085-1100
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    • 2023
  • For any given function f, we focus on the so-called prescribed mean curvature problem for the measure e-f(|x|2)dx provided thate-f(|x|2) ∈ L1(ℝn+1). More precisely, we prove that there exists a smooth hypersurface M whose metric is ds2 = dρ2 + ρ2d𝜉2 and whose mean curvature function is ${\frac{1}{n}}(\frac{u^p}{{\rho}^{\beta}})e^{f({\rho}^2)}{\psi}(\xi)$ for any given real constants p, β and functions f and ψ where u and ρ are the support function and radial function of M, respectively. Equivalently, we get the existence of a smooth solution to the following quasilinear equation on the unit sphere 𝕊n, $${\sum_{i,j}}({{\delta}_{ij}-{\frac{{\rho}_i{\rho}_j}{{\rho}^2+|{\nabla}{\rho}|^2}})(-{\rho}ji+{\frac{2}{{\rho}}}{\rho}j{\rho}i+{\rho}{\delta}_{ji})={\psi}{\frac{{\rho}^{2p+2-n-{\beta}}e^{f({\rho}^2)}}{({\rho}^2+|{\nabla}{\rho}|^2)^{\frac{p}{2}}}}$$ under some conditions. Our proof is based on the powerful method of continuity. In particular, if we take $f(t)={\frac{t}{2}}$, this may be prescribed mean curvature problem in Gauss measure space and it can be seen as an embedded result in Gauss measure space which will be needed in our forthcoming papers on the differential geometric analysis in Gauss measure space, such as Gauss-Bonnet-Chern theorem and its application on positive mass theorem and the Steiner-Weyl type formula, the Plateau problem and so on.

Mechanistic Significances of the Reactivity-Selectivity Principle

  • Lee, Ik Jun;Lee, Bon Su;Go, Han Jung;Jang, Byeong Du
    • Bulletin of the Korean Chemical Society
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    • v.16 no.3
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    • pp.277-281
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    • 1995
  • The relationship between the signs of ${\rho}i(0)$, ${\rho}j(0)$ and ${\rho}ij$ and validity of the reactivity-selectivity principle (RSP) has been derived: RSP is valid when W = ${\rho}i(0){\cdot}{\rho}j(0)/{\rho}ij$ is negative. The analysis of 100 reaction series indicated that for normal SN2 reactions involving variations of substituents in the nucleophile (X) and in the substrate (Y) RSP is valid only for a dissociative type for which ${\rho}Y(0)$ is negative, whereas for the acyl transfer reactions with rate-limiting breakdown of the tetrahedral intermediate RSP is valid in general for all substituent changes, X, Y and/or Z (substituent on the leaving group). The trends in the validity of RSP for certain types of reaction can be useful in supplementing the mechanistic criteria based on the signs of ${\rho}i(0)$, ${\rho}j(0)$ and ${\rho}ij$.

Cauchy problem for the Euler equations of a nonhomogeneous ideal incompressible fluid

  • Itoh, Shigeharu
    • Journal of the Korean Mathematical Society
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    • v.31 no.3
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    • pp.367-373
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    • 1994
  • Let us consider the Cauchy problem $$ {\rho_t + \upsilon \cdot \nabla\rho = 0 {\rho[\upsilon_t + (\upsilon \cdot \nabla)\upsilon] + \nabla p + \rho f {div \upsilon = 0 (1.1) {\rho$\mid$_t = 0 = \rho_0(x) {\upsilon$\mid$_t = 0 = \upsilon_0(x) $$ in $Q_T = R^3 \times [0,T]$, where $f(x,t), \rho_0(x) and \upsilon_0(x)$ are given, while the density $\rho(x,t)$, the velocity vector $\upsilon(x,t) = (\upsilon^1(x,t),\upsilon^2(x,t),\upsilon^3(x,t))$ and the pressure p(x,t) are unknowns. The equations $(1.1)_1 - (1.1)_3$ describe the motion of a nonhomogeneous ideal incompressible fluid.

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Some properties of equivalent fuzzy norms

  • Rhie, Gil-Seob;Hwang, In-Ah
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.5 no.2
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    • pp.175-178
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    • 2005
  • In the present paper, we observe a relation between fuzzy norms and induced crisp norms on a linear space. We first prove that if $\rho_1,\;\rho_2$ are equivalent fuzzy norms on a linear space, then for every $\varepsilon\in(0.1)$, the induced crisp norms $P_\varepsilon^1,\;and\;P_\varepsilon^2$, respectively are equivalent. Since the converse does not hold, we prove it under some strict conditions. And consider the following theorem proved in [8]: Let $\rho$ be a lower semicontinuous fuzzy norm on a normed linear space X, and have the bounded support. Then $\rho$ is equivalent to the fuzzy norm $\chi_B$ where B is the closed unit ball of X. The lower semi-continuity of $\rho$ is an essential condition which guarantees the continuity of $P_\varepsilon$, where 0 < e < 1. As the last result, we prove that : if $\rho$ is a fuzzy norm on a finite dimensional vector space, then $\rho$ is equivalent to $\chi_B$ if and only if the support of $\rho$ is bounded.

Kinetic Mechanism of Nucleotide Binding to Escherichia coli Transcription Termination Factor Rho: Stopped-flow Kinetic Studies Using ATP and Fluorescent ATP Analogues

  • Kim, Dong-Eun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.1
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    • pp.23-34
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    • 2004
  • Escherichia coli transcription termination factor Rho catalyzes the unwinding of RNA/DNA duplex in reactions that are coupled to ATP binding and hydrolysis. Fluorescence stopped-flow methods using ATP and the fluorescent 2'(3')-O-( N-methylanthraniloyl) derivatives (mant-derivatives) of ATP and ADP were used to probe the kinetics of nucleotide binding to and dissociation from the Rho-RNA complex. Presteady state nucleotide binding kinetics provides evidence for the presence of negative cooperativity in nucleotide binding among the multiple nucleotide binding sites on Rho hexamer. The binding of the first nucleotide to the Rho-RNA complex occurs at a bimolecular rate of 3.6${\times}$10$\^$6/ M$\^$-1/ sec$\^$-1/ whereas the second nucleotide binds at a slower rate of 4.7${\times}$10$\^$5/ M$\^$-1/ sec$\^$-1/ at 18$^{\circ}C$, RNA complexed with Rho affects the kinetics of nucleotide interaction with the active sites through conformational changes to the Rho hexamer, allowing the incoming nucleotide to be more accessible to the sites. Adenine nucleotide binding and dissociation is more favorable when RNA is bound to Rho, whereas ATP binding and dissociation step in the absence of RNA occurs significantly slower, at a rate ∼70- and ∼40-fold slower than those observed with the Rho-RNA complex, respectively.

QUADRATIC ρ-FUNCTIONAL INEQUALITIES IN BANACH SPACES: A FIXED POINT APPROACH

  • PARK, CHOONKIL;SEO, JEONG PIL
    • Korean Journal of Mathematics
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    • v.23 no.2
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    • pp.231-248
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    • 2015
  • In this paper, we solve the following quadratic $\rho$-functional inequalities ${\parallel}f(\frac{x+y+z}{2})+f(\frac{x-y-z}{2})+f(\frac{y-x-z}{2})+f(\frac{z-x-y}{2})-f(x)-x(y)-f(z){\parallel}\;(0.1)\\{\leq}{\parallel}{\rho}(f(x+y+z+)+f(x-y-z)+f(y-x-z)+f(z-x-y)-4f(x)-4f(y)-f(z)){\parallel}$ where $\rho$ is a fixed complex number with ${\left|\rho\right|}<\frac{1}{8}$, and ${\parallel}f(x+y+z)+f(x-y-z)+f(y-x-z)+f(z-x-y)-4f(x)-4f(y)-4f(z){\parallel}\;(0.2)\\{\leq}{\parallel}{\rho}(f(\frac{x+y+z}{2})+f(\frac{x-y-z}{2})+f(\frac{y-x-z}{2})+f(\frac{z-x-y}{2})-f(x)-f(y)-f(z)){\parallel}$ where $\rho$ is a fixed complex number with ${\left|\rho\right|}$ < 4. Using the fixed point method, we prove the Hyers-Ulam stability of the quadratic $\rho$-functional inequalities (0.1) and (0.2) in complex Banach spaces.

A Simple Algorithm for Factorial Experiments in $\rho^N$

  • Donwonn Kim
    • Communications for Statistical Applications and Methods
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    • v.5 no.2
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    • pp.353-359
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    • 1998
  • Factorial designs with two-level factors represent the smallest factorial experiments. The system of notation and confounding and fractional factorial schemes developed for the $2^N$system are found in standard textbooks of experimental designs. Just as in the $2^N$ system, the general confounding and fractional factorial schemes are possible in $3^N,5^N$, .... , and $\rho^N$ where $\rho$ is a prime number. Hence, we have the $\rho^N$ system. In this article, the author proposes a new algorithm for constructing fractional factorial plans in the $\rho^N$ system.

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Cullin 3/KCTD5 Promotes the Ubiqutination of Rho Guanine Nucleotide Dissociation Inhibitor 1 and Regulates Its Stability

  • Cho, Hee Jun;Ryu, Ki-Jun;Baek, Kyoung Eun;Lim, Jeewon;Kim, Taeyoung;Song, Chae Yeong;Yoo, Jiyun;Lee, Hee Gu
    • Journal of Microbiology and Biotechnology
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    • v.30 no.10
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    • pp.1488-1494
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    • 2020
  • Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays important roles in numerous cellular processes, including cell motility, adhesion, and proliferation, by regulating the activity of Rho GTPases. Its expression is altered in various human cancers and is associated with malignant progression. Here, we show that RhoGDI1 interacts with Cullin 3 (CUL3), a scaffold protein for E3 ubiquitin ligase complexes. Ectopic expression of CUL3 increases the ubiquitination of RhoGDI1. Furthermore, potassium channel tetramerization domain containing 5 (KCTD5) also binds to RhoGDI1 and increases its interaction with CUL3. Ectopic expression of KCTD5 increases the ubiquitination of RhoGDI1, whereas its knockdown by RNA interference has the opposite effect. Depletion of KCTD5 or expression of dominant-negative CUL3 (DN-CUL3) enhances the stability of RhoGDI1. Our findings reveal a previously unknown mechanism for controlling RhoGDI1 degradation that involves a CUL3/KCTD5 ubiquitin ligase complex.

TENSOR PRODUCTS OF C*-ALGEBRAS WITH FIBRES GENERALIZED NONCOMMUTATIVE TORI AND CUNTZ ALGEBRAS

  • Boo, Deok-Hoon;Park, Chun-Gil
    • Journal of the Chungcheong Mathematical Society
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    • v.13 no.1
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    • pp.139-144
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    • 2000
  • The generalized noncommutative torus $T_{\rho}^d$ of rank m was defined in [2]. Assume that for the completely irrational noncommutative subtorus $A_{\rho}$ of rank m of $T_{\rho}^d$ there is no integer q > 1 such that $tr(K_0(A_{\rho}))=\frac{1}{q}{\cdot}tr(K_0(A_{\rho^{\prime}}))$ for $A_{\rho^{\prime}}$ a completely irrational noncommutative torus of rank m. All $C^*$-algebras ${\Gamma}({\eta})$ of sections of locally trivial $C^*$-algebra bundles ${\eta}$ over $M=\prod_{i=1}^{e}S^{2k_i}{\times}\prod_{i=1}^{s}S^{2n_i+1}$, $\prod_{i=1}^{s}\mathbb{PR}_{2n_i}$, or $\prod_{i=1}^{s}L_{k_i}(n_i)$ with fibres $T_{\rho}^d{\otimes}M_c(\mathbb{C})$ were constructed in [6, 7, 8]. We prove that ${\Gamma}({\eta}){\otimes}M_{p^{\infty}}$ is isomorphic to $C(M){\otimes}A_{\rho}{\otimes}M_{cd}(\mathbb{C}){\otimes}M_{p^{\infty}}$ if and only if the set of prime factors of cd is a subset of the set of prime factors of p, that $\mathcal{O}_{2u}{\otimes}{\Gamma}({\eta})$ is isomorphic to $\mathcal{O}_{2u}{\otimes}C(M){\otimes}A_{\rho}{\otimes}M_{cd}(\mathbb{C})$ if and only if cd and 2u - 1 are relatively prime, and that $\mathcal{O}_{\infty}{\otimes}{\Gamma}({\eta})$ is not isomorphic to $\mathcal{O}_{\infty}{\otimes}C(M){\otimes}A_{\rho}{\otimes}M_{cd}(\mathbb{C})$ if cd > 1 when no non-trivial matrix algebra can be ${\Gamma}({\eta})$.

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