• 대한임상독성학회지
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• 제1권1호
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• pp.21-26
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• 2003

Methamphetamine (MA) is a major drug of abuse in Korea. Currently preliminary evidence suggests that MA dependence may cause long-term neural damage in human. Repeated exposure to psychostimulants such as methamphetamine results in behavioral sensitization, a paradigm thought to be relevant to drug craving and addiction in human. Sensitization alters neural circuitry involved in normal processes of incentrive, motivation, and reward. However the precise mechanism of this behavioral sensitization has not yet been fully elucidated. Repeated use of high dose MA causes neurotoxicity which is characterized by a long-lasting depletion of striatal dopamine (DA) and tyrosin hydroxylase activity of DA, DA-transporter binding sites in the striatum. The loss of DA transporters correlates with memory problems and lack of motor coordination. DA fuels motivation and pleasure, but it' s also crucial for learning and movement. This selective review provides a summary of studies that assess the neurobiological mechanisms of MA.

• 동의생리병리학회지
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• 제27권2호
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• pp.261-267
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• 2013

The purpose of this study was to examine the psychometric structure of Sasang typology with four personality measures and examine the construct validity of Sasang Personality Questionnaire (SPQ). We measured biopsychological traits of 104 university students using SPQ, Temperament and Character Inventory (TCI), NEO-Personality Inventory (NEO-PI) and Myers-Briggs Type Indicator (MBTI). The construct validity of SPQ was analyzed with TCI, NEO-PI and MBTI using Pearson's correlation. The temperament features of each Sasang groups were compared with Analysis of Variance and Profile Analysis. The SPQ showed significant correlation with TCI Novelty-Seeking (r=.398), TCI Harm-Avoidance (r=-.333), TCI Reward-Dependence (r=.465), TCI Self-Directedness (r=0.340), NEO-PI Extraversion (r=0.489) and MBTI Extraversion-Introversion (r=-0.509). The SPQ, TCI and NEO-PI revealed significant differences between Sasang constitutional groups. We examined the temperament construct of the Sasang typology and the validity of SPQ with well established western biopsychosocial instruments. This study would contribute to the objective studies on the biopsychosocial mechanism of Sasang medicine.

• 한국학교보건학회지
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• 제23권2호
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• pp.181-191
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• 2010

Purpose: The purpose of this study is to analyze the drinking status and to identify the impacts of depression, temperament, characteristic on drinking status in the vocational high school students. Methods: By using stratified sampling, 416 vocational high school students in Gangwon Do were selected and surveyed through self -administered questionnaires. Data were analyzed by SPSS 12.0 using $x^2$-test, t-test, ANOVA, Pearson correlation coefficient and multiple regression. Results: 88% of students had experienced of drinking. Depression was observed 59.1% of students from light to severe depression score. There was a positive correlation among drinking, the school records, novelty seeking, reward dependence and persistence. Also, there was a negative correlation among drinking, economic status, harm avoidance. The significant predictors of drinking were school records, depression, novelty seeking and persistence. Conclusion: These results suggest that vocational high school students who have the factors identified in this study are regarded as having the potential to drink. The results of this study can provide the information for the development of the health promotion program.

• 한국농촌간호학회지
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• 제2권1호
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• pp.14-23
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• 2007

Purpose: The purpose of this study was to analyze the smoking behaviors and to identify the impact of depression, temperament, and characteristics of smoking experience on rural adolescents. Method: A survey using a self-administered questionnaire was done of 310 rural high school students. Using SPSS 12.0, Pearson correlation coefficients and multiple regression were used to analyze the data. Results: The smoking rate of rural high school students was higher than that of the national rate for this age group. Serious depression was observed in the rural high school students. There was a positive correlation among smoking experience, school records, novelty seeking and a negative correlation between smoking and cooperativeness. The significant predictors of smoking experience were type of school, satisfaction with school, school records, novelty seeking, reward dependence and cooperativeness. These factors accounted for 38.9% of variances in the smoking experience of rural adolescents. Conclusion: These results suggest that adolescents who exhibit factors identified in this study are regarded as having the potential to smoke, and this result proposes the basis for program development for the prevention of smoking and smoking cessation.

• 사상체질의학회지
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• 제27권4호
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• pp.396-403
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• 2015

Objectives The purpose of this study was to analyze the characteristics of each Soyang constitutional Exterior and Interior disease's favorable-unfavorable pattern using the Temperament and Character Inventory(TCI) in a Korean adult clinical sample.Methods A total of 32 subjects(age 20-49) completed the Korean version of the TCI. A Sasang Constitutional Medicine specialist determined each subject's Sasang constitutional type based on the Questionnaire for Sasang Constitution Diagnosis(QSCC∥) and comprehensive constitutional assessment. The participants consisting of 15 favorable pattern, 17 unfavorable pattern.Results Among the four temperament dimensions, the favorable pattern showed significantly higher scores than the unfavorable pattern in Novelty Seeking(NS) and Reward Dependence(RD). Among the three character dimensions, the unfavorable pattern showed significantly higher score than the favorable pattern subjects in Self-Directedness(SD).Conclusions Differences in temperament and character were discovered across the Soyang Constitutional disease's Exterior and Interior disease's favorable-unfavorable pattern.

• Child Health Nursing Research
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• 제18권4호
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• pp.207-213
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• 2012

Purpose: This study was done to examine levels of temperament, parent-child attachment and depression of adolescents and verify its effects. Methods: Surveys were conducted with 500 students from two middle schools, one located in Seoul and one in Gyeonggi Province. Adolescent temperament was measured using the Junior Temperament and Character Inventory, parent-child attachment using the Revised Inventory of Parent and Peer Attachment and depression using the Children's Depression Inventory. Cluster, t-test, correlation and logistic regression were used for data analysis. Results: Characteristics of temperament were classified into 2 groups. The 'Adaptation vulnerable group' showed high Harm Avoidance and the 'Adaptation protective group' showed high Reward Dependence, and Patience. The 'Adaptation vulnerable group' showed lower attachment and higher depression than the 'Adaptation protective group'. Novelty Seeking and Harm Avoidance correlated positively with depression and negatively with attachment. Students with higher levels of attachment reported lower levels of depression. The logistic regression analysis showed that the 'Adaptation vulnerable group' was 2.16 times more likely to be affected by depression than 'Adaptation protective group'. Conclusion: Results of this study can be used to develop depression intervention programs for adolescent psychological health and provide encouragement in the development of parent-child attachment.

• 지역사회간호학회지
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• 제18권3호
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• pp.441-451
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• 2007

Purpose: The purpose of this study is to analyze the smoking behaviors and to identify the impacts of depression, temperament, and characteristic on smoking experience in the female adolescents. Methods: This study surveyed 691 highschool girls in the Gangwon area using self -administered questionnaires. Data were analyzed by SPSS 12.0. using Pearson correlation coefficient and multiple regression. Results: The smoking rate of the highschool girls was lower than that of the national average. Depression was observed to be seriously in the highschool girls. There were a positive correlations among smoking experience, the school records and novelty seeking and a negative correlation between smoking and cooperativeness. The significant predictors of smoking experience were the type of school, the satisfaction with school the school records, novelty seeking, reward dependence and cooperativeness. Conclusion: These results suggest that femalel adolescents who have the factors identified in this study are considered to have the potential for smoking. These results provide the basis for developing smoking prevention and cessation programs.

• 동의신경정신과학회지
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• 제22권3호
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• pp.55-64
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• 2011

Objectives : The purpose of this study was to compare the profiles of Junior Temperament and Character Inventory (JTCI) and Sasang constitution in middle school students. Methods : In this study, healthy 89 students(13 to 15 years old) except for 3 Taeyangin were analyzed; 37 Soyangin, 30 Taeeumin, 22 Soeumin. The Sasang Constitutional types were determined by the results of TS-QSCD(Two Step Questionnaire for Sasang Constitution Diagnosis) and the seven dimensions JTCI 12-18(The Junior Temperament and Character Inventory) were compared among the different Sasang types using analysis of variance(ANOVA). Results : In the temperament dimensions, Soyangin showed significantly higher score than Taeeumin and Soeumin in Novelty Seeking(NS). Soeumin showed significantly higher score than Soyangin in Harm Avoidance(HA). Soyangin showed significantly higher score than the others in RD(Reward Dependence) (Soyangin>Soeumin>Taeeumin). In the character dimensions, Soyangin showed significantly higher score than Soeumin in SD(Self-Directness). There were no significant differences in P(Persistence), and C(cooperativeness) and ST(self-transcendence). Conclusions : These results demonstrate that there are some differences of the temperaments and characters among Sasang types and could help adolescents to understand and develope themselves.

• International Journal of Internet, Broadcasting and Communication
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• 제13권1호
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• pp.219-228
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• 2021

The aim of this study was to investigate the learning styles with personalities of medical students which may affect the efficiency of teaching-learning system of clinical education to determine the association with the clinical performance examination achievement of the students. The learning styles and personality traits of 147 students of medical college were investigated. The obtained data were analyzed by statistical analysis including independent t-test and correlation analysis. The results of the analyses are as follows: there was significant difference in the participation model in the different genders; of the personality traits, there was significant difference in self-transcendence in the different genders, whereas there was significant difference in the persistence for past failure experiences; and there was significant association between the 6 sub-learning models(Independent vs. Dependent, Collaborative vs. Competitive, and Participant vs. Avoidant learning styles) and the personality traits(Novelty Seeking, Harm Avoidance, Reward Dependence, Persistence, Self-directedness, Cooperativeness and Self-transcendence). In addition, the participant type of students had higher scholastic achievements in clinical performance, and the students who scored high in self-transcendence and persistence also had higher clinical performance. In conclusion, the student's learning style and personalities affected the clinical scholastic performance. We believe that considering this current study, it would be possible to improve the quality of clinical education of medical teaching as well as helping medical students to choose career paths that are suitable for their personalities.

• 생물정신의학
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• 제19권4호
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• pp.199-204
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• 2012

Objectives In the previous studies, it has been suggested that temperament and character may affect specialty choice in medical students. The aim of this study is to investigate the effects of temperament and character on specialty interests in medical students. Methods A total 132 third-year medical students initially participated in this study. Among these participants, 128 students had filled out both demographic and Temperament and Character Inventory (TCI) questionnaires. Socio-demographic data, specialty interests and Cloninger's TCI scores were obtained. The specialty interests were categorized into surgical, medical and other departments. Results Among 128 students, 88 (68.7%), 29 (22.7%) and 22 (8.6%) students chose medical, surgical and other departments, respectively. Students choosing surgery departments showed lower Harm Avoidance scores (F = 4.39, df = 1, p = 0.04) and higher Self-Directedness scores (F = 4.30, df = 1, p = 0.04) than those who chose medical departments. There was no significant differences in Novelty Seeking, Reward dependence, Persistence, Cooperativeness, Self-Transcendence scores between groups. Conclusions To the best of our knowledge, this is the first study that has demonstrated the relationship between TCI scores and specialty interests of medical students in Korea. The current study suggests that temperament and character influence specialty interests in medical students. These findings could have implications for medical education research and career counseling.