• Title/Summary/Keyword: Reversal method

Search Result 246, Processing Time 0.032 seconds

Multidrug resistance reversal in mouse lymphoma cells by indian tea leaves, indian coffee seeds and chicory

  • Rao, Bhattiproulu Kesava;Motohashi, Noboru;Kawase, Masami;Spengler, Gabriella;Molnar, Joseph
    • Advances in Traditional Medicine
    • /
    • v.3 no.2
    • /
    • pp.100-105
    • /
    • 2003
  • Systematic analysis of caffeine from the commercial samples of Indian tea leaves was performed by a routine method and the content of caffeine was found to be 19.0-37.4 mg/100 g leaves. The caffeine contents from coffee seeds and chicory from Indian origin were analyzed and found to be 0.6540-1.4920 g/100 g seeds. Caffeine contents of roasted Indian chicory roots were lower than either those of Indian tea leaves or Indian coffee seeds. The multidrug resistance (MDR) reversing effects were tested on a mouse leukemia cell line of L-5178 cells by methanol extracts [M1-M15] of Indian tea leaves and coffee seeds, comparing to a control of $({\pm})-verapamil$. The effects were measured by fluorescence ratio between treated and untreated group cells. Among fifteen methanol extracts, a Gemini tea [M6] (fluorescence activity ratio 5.26) had the most potent effect for L-5178 cells. The extract M6 was 0.63-fold of $({\pm})-verapamil$. We suggest that one of mechanisms of reversal by M6 might have strong affinity to dopamine $D_1$ and D_2$ receptors. Further studies with many more tumor and normal cell lines are necessary to confirm the MDR reversal specificity of coffee methanol extracts.

How to make spatially focused sound shape: wavenumber spectrum matching (공간 상에 원하는 음장형상을 만드는 방법)

  • Park, Jin-Young;Kim, Yang-Hann
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2007.11a
    • /
    • pp.1014-1017
    • /
    • 2007
  • Sound focusing technologies has been studied for various purposes from early 1990s. As a result, these technologies make us possible to apply in many uses. For example, we can treat tumors using focused ultrasonic waves without surgical knife and communicate in the ocean using time reversal array. Also applications for personal audio system become issues. Recently, as technologies are developing, in some applications, needs for regional focusing become increasing because previously suggested focusing methods, such as phase conjugation, time reversal and inverse filtering, were all about a point focusing. Therefore, studies on regional focusing method are essentially needed. Regional focusing method was firstly mentioned by Choi and Kim in 2002: acoustic contrast control. However, in regional focusing, physical interpretations between control variables and results are still not easy because of its complexity. In this regard, we tried to understand the relations between control variables and results in wavenumber domain and suggested a solution method for regional focusing: wavenumber spectrum matching. We also showed how to make spatially focused sound shape using the suggested method from the simplest case: line focusing.

  • PDF

Electrical properties of the PLZT thin film capacitors by the sol-gel method (Sol-gel법을 이용한 PLZT박막 커패시터의 전기적 특성)

  • 박준열;정장호;이성갑;이영희
    • Electrical & Electronic Materials
    • /
    • v.9 no.7
    • /
    • pp.668-673
    • /
    • 1996
  • In this paper, (P $b_{1-x}$ L $a_{x}$)(Z $r_{0.52}$ $Ti_{0.48}$) $O_{3}$ (X=0-13[at%]) thin film were prepared by the Sol-Gel method, Multiple PLZT thin films were spin-coated on the Pt/Ti/ $SiO_{2}$Si substrate. The electrical properties of the films were investigated for varying the annealing temperature. In the PLZT(11/52/48) specimens, the dielectric ocnstant of 1236 and the polarization reversal time of 460[nm] were obtained and the breakdown of the film did not occur up to 1*10$^{10}$ cycles at the voltage of 7[V] by the bipolar acceleration. The remanent polarization and coercive field decreased with increasing the content of La in the range of 0-13[at%] and thin film of the PLZT(11/52/48) showed the value of 2.56[.mu.C/c $m^{2}$] and 21.1[kV/cm], respectively.ly.y.

  • PDF

Determination of Impact Source Location Using a Single Transducer and Time Reversal Technique (단일센서와 시간역전법을 이용한 판에서의 충격위치 결정에 관한 연구)

  • Jeong, Hyun-Jo;Cho, Sung-Jong
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.32 no.1
    • /
    • pp.47-55
    • /
    • 2012
  • A structural health monitoring technique for locating impact position in a plate structure is presented in this paper. The method employs a single sensor and spatial focusing of time reversal (TR) acoustics. We first examine the TR focusing effect at the impact position and its surroundings through simulation and experiment. The imaging results of impact points show that the impact source location can be accurately estimated in any position of the plate. Compared to existing techniques for locating impact or acoustic emission source, the proposed method has the benefits of using a single sensor and not requiring material properties and geometry of structures. Furthermore, it does not depend on a particular mode of dispersive Lamb waves that is frequently used in other ultrasonic testings of plate-like structures.

Development of High Voltage and High Energy Density Capacitor for Pulsed Power Application (펄스파워용 고전압 고에너지밀도 커패시터 개발)

  • 이병윤;정진교;이우영;박경엽;이수휘;김영광
    • The Transactions of the Korean Institute of Electrical Engineers B
    • /
    • v.52 no.5
    • /
    • pp.203-210
    • /
    • 2003
  • This paper describes high voltage and high energy density capacitor developed for pulsed power applications. The rated voltage of the developed capacitor is DC 22 [kV], the capacitance is 206 [$\mu$F] and the energy density is about 0.7 [kJ/kg]. Polypropylene film and kraft paper were used as the dielectrics. The ratio of the thickness of each dielectric material which consists of the composite dielectric structure, stacking factor and the termination method were determined by the charging and discharging tests on model capacitors. In terms of energy density, the developed capacitor has higher energy density compared with the products of foreign leading companies. In addition, it has been proved that the life expectancy can be more over 2000 shots through the charging and discharging test. The voltage reversal factor was 20%. This capacitor can be used as numerous discharge applications such as military, medical, industrial fields.

The rapid thermal annealing effects and its application to electron devices of Sol-Gel derived ferroelectric PZT thin films (졸-겔법으로 형성한 강유전체 PZT박막의 고온 단시간 열처리효과 및 전자 디바이스에의 응용)

  • 김광호
    • Electrical & Electronic Materials
    • /
    • v.7 no.2
    • /
    • pp.152-156
    • /
    • 1994
  • The rapid thermal annealing effects of Sol-Gel derived ferroelectric PZT thin films were investigated. It was found that rapid thermal annealing(RTA) of spin coated thin films on silicon typically >$800^{\circ}C$ for about 1 min. was changed to the perovskite phase. Rapid thermally annealed films recorded maximum remanent polarization of about 5 .mu.C/cm$^{2}$, coercive field of around 30kV/cm. The switching time for polarization reversal was about 220ns. The films of RTA process showed smooth surface, and high breakdown voltages of over 1 MV/cm and resistivity of $1{\times}{10^12}$ .ohm.cm at 1 MV/cm. It was verified that the polarization reversal of the PZT film was varied partially with applying the multiple short pulse.

  • PDF

Trading Using Trend Reversal Pattern Recognition in the Korea Stock Market (추세 반전형 패턴 인식을 이용한 주식 거래)

  • Kwon, Soonchang
    • Korean Management Science Review
    • /
    • v.30 no.1
    • /
    • pp.43-58
    • /
    • 2013
  • Although analysis of charts, which used in stock trading by distinguishing standardized patterns in the movements of stock prices, is simple and easy to use, there can be problems stemming from specific patterns being distinguished as a result of the subjective perspectives of analysts. In accordance with such problems, through the method of template pattern matching, 4 trend reversal patterns were designed and the fitness of the patterns were quantitatively measured. In cases when a stock is purchased when the template pattern fitness value is within a certain range and held for at least 20-days, the average return ratio was analyzed to be higher-with the difference being statistically significant-than the average return ratio attained from trading a stock according to the same method per the Efficient Market Hypothesis. From the results of stock trades of 2 domestic corporations to which the values of the 4 patterns had been applied based on the 4 strategies, it was possible to ascertain differences in the strategy- and pattern-dependent return ratios. Through this study, along with presenting the exceptions for the Efficient Market Hypothesis in stock trading, the fitness level of quantitative chart patterns was measured and the theoretical basis for application of such fitness level was proposed.