• International Journal of Oral Biology
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• 제30권2호
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• pp.71-76
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• 2005

The mesencephalic trigeminal nucleus (Mes V) contains cell bodies of primary afferent sensory neurons that relay proprioceptive information from the periodontium and masticatory muscles and function as typical sensory neurons or potentially as integrative interneurons. In the present study, we studied these two potential functions using combined experimental approaches of retrograde labeling and whole cell patch clamp recording. Mes V neurons that presumably originate from periodontal nerve fibers in subsets of Mes V nucleus were identified by retrograde labeling with a fluorescent dye, DiI, which was applied onto inferior alveolar nerve. These cells were elliptical perikarya shaped cells about $40{\mu}m$ in diameter. In these neurons, we measured high voltage-activated calcium channel (HVACC) currents. $GABA_B$ agonist, baclofen, inhibited calcium currents, and the HVACC currents inhibition by baclofen was voltage-dependent, exhibited prepulse facilitation, indicating that it was mediated by $G_i/_G_o$ protein. Taken together, our results demonstrate that Mes V neurons not only have cell bodies originating from periodontium, but also receive synaptic inputs including GABAergic neurons suggesting that Mes V neurons function as both primary sensory neurons and integrative interneurons.

• Journal of Trauma and Injury
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• 제24권2호
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• pp.136-142
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• 2011

Purpose: Blunt pancreatic injury has a high mortality rate, especially if adequate management is delayed. Although many guidelines exist for diagnosis and treatment, there is no consensus to date. Therefore, we analyzed the role of endoscopic retrograde cholangiopancreatography (ERCP) as a diagnostic and therapeutic tool for the treatment of traumatic pancreatic injury. Methods: We retrospectively reviewed the electronic medical records (EMR) database at Asan Medical Center (Seoul, South Korea) to identify all patients diagnosed with trauma to the pancreas between June 2003 and December 2010. Clinical and operative findings, CT (computed tomography) images, and ERCP findings were assessed. Results: A total of 40 patients were evaluated in this study. Of these, 14 patients underwent diagnostic ERCP, and 26 did not. Of the 14 patients who underwent diagnostic ERCP, 5 were found to have normal pancreatic ducts, thereby preventing a needless laparotomy in these patients. Of the patients diagnosed with ductal injury, four were treated with endoscopic intervention, and four underwent an exploratory laparotomy. The remaining patient was treated with radiologic intervention (percutaneous drainage) to manage pancreatic pseudocyst formation. Conclusion: Our findings suggest that ERCP is a beneficial diagnostic and therapeutic modality for the treatment of traumatic pancreatic injury.

• 구강회복응용과학지
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• 제30권3호
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• pp.259-264
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• 2014

역행성 임플란트 근단병소 주위염은 임상증상을 동반한 근단부의 방사선 투과성 병소로 정의되며 임플란트 식립부위 또는 인접한 치아의 잔존하고 있는 감염에서 유래한 세균감염, 골 삭제시의 열 발생 등의 다양한 원인에 의해 야기될 수 있고, 다양한 치료방법으로 임플란트를 제거하지 않고 유지할 수 있는 증례들이 보고되고 있다. 본 증례에서는 근관 치료 실패로 발치한 상악 우측 제2소구치 부위에 식립한 임플란트에서 발생한 역행성 임플란트 근단병소 주위염을 표면의 detoxification과 차폐막과 골이식재를 동반한 골유도재생술로 해결하여 기능을 회복하였으며, 7년간 장기적으로 안정적으로 유지되고 있는 증례에 대해 보고하고자 한다.

• 천문학회보
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• 제42권2호
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• pp.51.1-51.1
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• 2017

We present the dependence of halo properties on two different Galactic potentials: the $St{\ddot{a}}ckel$ potential and the Milky Way-like potential known as "Galpy". Making use of the Sloan Digital Sky Survey Data Release 12 (SDSS DR12), we find that the shape of the metallicity distribution and rotation velocity distribution abruptly changes at 15 kpc of $Z_{max}$ (the maximum distance of stellar orbit above or below the Galactic plane) and 32 kpc of $r_{max}$ (the maximum distance of an orbit from the Galactic center) in the $St{\ddot{a}}ckel$, which indicates that the transition from the inner to outer halo occurs at those distances. When adopting the $St{\ddot{a}}ckel$ potential, stars with $Z_{max}$ > 15 kpc show a retrograde motion of $V_{\phi}=-60km\;s^{-1}$, while stars with $r_{max}$ > 32 kpc show $V_{\phi}=-150km\;s^{-1}$. If we impose $V_{\phi}$ < $-150km\;s^{-1}$ to the stars with $Z_{max}$> 15 kpc or $r_{max}$> 32, we obtain the peak of the metallicity distribution at [Fe/H] = -1.9 and -1.7 respectively. However, there is the transition of the metallicity distribution at $Z_{max}=25kpc$, whereas there is no noticeable retrograde motion in the Galpy. The reason for this is that stars with high retrograde motion in the $St{\ddot{a}}ckel$ potential are unbound and stars with low rotation velocity reach to larger region of $Z_{max}$ and $r_{max}$ due to shallower potential in the Galpy. These results prove that as the adopted Galactic potential can affect the interpretation of the halo properties, it is required to have a more realistic Galactic potential for the thorough understanding of the dichotomy of the Galactic halo.

• Restorative Dentistry and Endodontics
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• 제19권2호
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• pp.499-512
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• 1994

The purpose of this study was to evaluate the microleakage electrochemically using different retrograde filling materials, different root resection angle, and different cavity preparation instruments. 104 extracted single-rooted teeth were selected for this study. 100 teeth were used as experimental groups and four was used as controls. Anatomical crowns were resected, root canals were prepared, and the apical 2 mm of roots were removed. The experimental roots were randomly divided into five equal groups. Experimental groups : Group 1. no bevel, cavity preparation with ultrasonic instruments, amalgam filling Group 2. no bevel, cavity preparation with ultrasonic instruments, SuperEBA cement filling Group 3. no bevel, cavity preparation with ultrasonic instruments, desiccated ZOE filling Group 4. $45^{\circ}$ bevel, cavity preparation with ultrasonic instruments, amalgam filling Group 5. no bevel, cavity preparation with conventional bur, amalgam filling Microleakage was measured once a day for 30 days using electrochemical method and were analyzed statistically. The results were as follows : 1. The group with Super EBA cement filling showed the least marginal leakage from second to fourth day(p<0.05), there was no significant difference between the group with amalgam filling during eighth to eighteenth day(p>0.05), but after the nineteenth day here was a higher marginal leakage than the group with amalgam filling(p<0.05). 2. The group with desiccated ZOE filling demostrated that the highest marginal leakage, started on the eighth day(p<0.05). 3. The group using ultrasonic instrument showed lower marginal leakage than the group using bur until the nineteenth day(p<0.05), but there was no significant differnce with the group using bur after twentythird day(p>0.05). 4. The group without bevel showed lower marginal leakage than the group with bevel (p<0.05). 5. Whether bevel or nor had much more effect on marginal leakage than with cavity perparation instrument when the cavity was retrogrdefilled with amalgam(stepwise regression).

• Restorative Dentistry and Endodontics
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• 제43권2호
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• pp.23.1-23.9
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• 2018

Objectives: This study evaluated the effect of ultrasonic agitation of mineral trioxide aggregate (MTA), calcium silicate-based cement (CSC), and Sealer 26 (S26) on adaptation at the cement/dentin interface and push-out bond strength. Materials and Methods: Sixty maxillary canines were divided into 6 groups (n = 10): MTA, S26, and CSC, with or without ultrasonic activation (US). After obturation, the apical portions of the teeth were sectioned, and retrograde cavities were prepared and filled with cement by hand condensation. In the US groups, the cement was activated for 60 seconds: 30 seconds in the mesio-distal direction and 30 seconds in the buccal-lingual direction, using a mini Irrisonic insert coupled with the ultrasound transducer. After the materials set, 1.5-mm thick sections were obtained from the apexes. The presence of gaps and the bond between cement and dentin were analyzed using low-vacuum scanning electron microscopy. Push-out bond strength was measured using a universal testing machine. Results: Ultrasonic agitation increased the interfacial adaptation of the cements. The S26 US group showed a higher adaptation value than MTA (p < 0.05). US improved the push-out bond strength for all the cements (p < 0.05). Conclusions: The US of retrograde filling cements enhanced the bond to the dentin wall of the root-end filling materials tested.

• Gut and Liver
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• 제12권6호
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• pp.704-713
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• 2018

Background/Aims: Gastric varices (GVs) are a major cause of upper gastrointestinal bleeding in patients with liver cirrhosis. The current treatments of choice are balloon-occluded retrograde transvenous obliteration (BRTO) and the placement of a transjugular intrahepatic portosystemic shunt (TIPS). We aimed to compare the efficacy and outcomes of these two methods for the management of GV bleeding. Methods: This retrospective study included consecutive patients who received BRTO (n=157) or TIPS (n=19) to control GV bleeding from January 2005 to December 2014 at a single tertiary hospital in Korea. The overall survival (OS), immediate bleeding control rate, rebleeding rate and complication rate were compared between patients in the BRTO and TIPS groups. Results: Patients in the BRTO group showed higher immediate bleeding control rates (p=0.059, odds ratio [OR]=4.72) and lower cumulative rebleeding rates (logrank p=0.060) than those in the TIPS group, although the difference failed to reach statistical significance. There were no significant differences in the rates of complications, including pleural effusion, aggravation of esophageal varices, portal hypertensive gastropathy, and portosystemic encephalopathy, although the rate of the progression of ascites was significantly higher in the BRTO group (p=0.02, OR=7.93). After adjusting for several confounding factors using a multivariate Cox analysis, the BRTO group had a significantly longer OS (adjusted hazard ratio [aHR]=0.44, p=0.01) and a longer rebleeding-free survival (aHR=0.34, p=0.001) than the TIPS group. Conclusions: BRTO provides better bleeding control, rebleeding-free survival, and OS than TIPS for patients with GV bleeding.

• Journal of Korean Neurosurgical Society
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• 제64권5호
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• pp.740-750
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• 2021

Objective : Retrograde suction decompression (RSD) is an adjuvant technique used for the microsurgical treatment of large and giant internal carotid artery (ICA) aneurysms. In this study, we analyzed the efficacy and safety of the RSD technique for the treatment of large and giant ICA aneurysms relative to other conventional microsurgical techniques. Methods : The aneurysms were classified into two groups depending on whether the RSD method was used (21 in the RSD group vs. 43 in the non-RSD group). Baseline characteristics, details of the surgical procedure, angiographic outcomes, clinical outcomes, and procedure-related complications of each group were reviewed retrospectively. Results : There was no significant difference in the rates of complete neck-clipping between the RSD (57.1%) and non-RSD (67.4%) groups. Similarly, there was no difference in the rates of good clinical outcomes (modified Rankin Scale score, 0-2) between the RSD (85.7%) and non-RSD (81.4%) groups. Considering the initial functional status, 19 of 21 (90.5%) patients in the RSD group and 35 of 43 (81.4%) patients in the non-RSD group showed an improvement or no change in functional status, which did not reach statistical significance. Conclusion : In this study, the microsurgical treatment of large and giant intracranial ICA aneurysms using the RSD technique obtained competitive angiographic and clinical outcomes without increasing the risk of procedure-related complications. The RSD technique might be a useful technical option for the microsurgical treatment of large and giant intracranial ICA aneurysms.

• 대한정형외과학회지
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• 제56권6호
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• pp.535-539
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• 2021

대퇴골 골절 이후 발생하는 혈관계 합병증은 드물지만 발생할 경우 심각한 문제를 초래할 수 있다. 근위 대퇴골 골절에서 직접적인 외상 혹은 근위대퇴골 골수 정 고정술 후 발생한 가성동맥류에 대해서는 몇 차례 증례보고가 있었다. 저자들은 85세 여환에서 원위대퇴골 골절에 대하여 역행성 골수 정 고정술 시행 후, 수술 후 9일째부터 혈색소 감소와, 종창, 통증이 발생했던 것에 대해 수술 후 일시적인 혈종 및 통증으로 오인하였다가, 수술 후 16일째가 되어서야 근위 교합 나사 주변부에서 외측 대퇴 회선 동맥의 하행분지에서 기원한 가성동맥류를 진단하였고, 경피적 혈관 색전술을 시행하여 치료 하였다. 시술 후 혈색소 상승 및 종창, 통증 감소 소견을 보이며 회복하였다.

• 대한정형외과학회지
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• 제56권2호
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• pp.183-189
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• 2021

슬관절 고정술은 슬관절이 손상되어 재건술을 시행할 수 없는 환자에서 안정적이고 통증이 없는 슬관절을 얻을 수 있는 마지막 선택사항 중 하나이다. 슬관절 고정술에는 외고정 장치, 압박 금속판을 이용한 내고정, 조립형 금속정 또는 이상와로부터 삽입하는 전향적 금속정을 이용한 내고정 등 다양한 방법들이 사용되어 왔다. 다른 선택사항으로 Neff 정, Wichita 정, 또는 Huckstep 정과 같은 짧은 금속정을 이용하기도 한다. 그러나 한국에서는 현재 사용 가능한 상용화된 짧은 금속정이 없다. 이에 저자들은 역행성 대퇴부 골수강 내 금속정을 이용한 슬관절 고정술을 보고하고자 한다.