• 한국환경생태학회지
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• 제32권6호
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• pp.639-645
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• 2018

본 연구는 제2차 국립공원 구역조정 시기(2010년~2011년) 해제된 지역의 용도지역, 건축물 조성 등 실제 건축 행위, 토지이용환경, 개별공시지가 등 사회 환경적 요인의 변화를(2011년${\rightarrow}$2018년), 같은 기간 존치지역의 사회 환경 요인과 비교를 통해 구역조정 영향을 분석하고자 하였다. 그리하여 제2차 국립공원 구역조정의 문제점을 파악하고 제3차 구역조정시의 대안적 시사점을 모색하고자 하였다. 해제지역의 용도지역은 계획 생산 보전관리지역으로의 변화가 약 80.4%로 가장 높았고, 농림지역으로 변화가 15.6%였으며 4.0%는 자연환경보전지역으로 유지되어 변화가 없었다. 건축물 조성 규모 변화는 해제지역은 2011년 이후 약 $106m^2$의 평균 건축이 이루어 진 반면 존치지역은 $91m^2$의 평균 건축이 진행된 것으로 분석되었다. 토지이용환경의 변화 요소로써 자연지역에서 인공지역으로의 변화율은 해제지역이 1.9%였고 존치지역은 0.7%로써 해제지역의 변화율이 높았다. 개별공시지가는 해제지역의 증가량은 11,911원이었고 존치지역은 4,413원으로 두 지역 모두 상승하였으며, 두 지역 간 공시지가 차이는 약 2.5배에 달했다. 국립공원내 지역주민의 사유재산권에 대한 문제는 중요한 과제이나 제2차 국립공원 구역조정으로 상당수 해소 되었으므로 이후에는 공원용도지구계획과 공원시설계획에 대한 면밀한 분석으로 합리적 대안을 제시함으로써 공원 주민의 편익을 도모할 필요가 있다. 또한 공원관리청이 주민과 상생 협력하고 국립공원내 거주민으로서 자부심을 가질 수 있도록 지원 체계 마련이 필요할 것으로 판단된다.

• Journal of Periodontal and Implant Science
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• 제48권4호
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• pp.224-235
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• 2018

Purpose: The purpose of this study was to evaluate the effects of platelet-rich plasma (PRP) on periodontal healing of replanted root surfaces in dogs histologically and histomorphometrically. Methods: A total of 36 roots of mandibular incisors and premolars from 6 mongrel dogs were used. The roots were randomly divided into 3 groups: 1) a positive control group (n=12), in which the periodontal ligament (PDL) and cementum were retained and the roots were soaked in saline; 2) a negative control group (n=12), in which the PDL and cementum were removed and the roots were soaked in saline; and 3) an experimental group (n=12), in which the PDL and cementum were removed and the roots were soaked in PRP. After soaking the root surfaces, the extracted roots were replanted into the extraction sockets. The roots were covered using a coronally repositioned flap Results: Histologically, irregular-thickness PDL-like and cementum-like tissues were observed in the 4-week experimental group and the positive control group. PDL-like tissue and cementum-like tissue with a more uniform thickness were observed at 8 weeks. In the negative control group, PDL-like tissue and cementum-like tissue were rarely found, and root resorption and ankylosis were observed. In the cross-sectional histomorphometric analysis, the experimental group demonstrated a higher rate of formation of cementum-like tissue and a lower tooth ankylosis rate than the positive and negative control groups at 4 and 8 weeks. Although there was a significant difference in the tooth ankylosis rate and the formation of cementum-like tissue across the 3 groups (P<0.05), no statistical significance was observed between any pair of groups (P>0.017). Conclusions: Applying PRP to root surfaces during tooth replantation in dogs can reduce tooth ankylosis and increase PDL-like and cementum-like tissue formation.

• Reproductive and Developmental Biology
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• 제34권3호
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• pp.143-151
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• 2010

Pluripotency of human embryonic stem cell (hESC) is one of the most valuable ability of hESCs for applying cell therapy field, but also showing side effect, for example teratoma formation. When transplant multipotent stem cell, such as mesnchymal stem cell (MSC) which retains similar differentiation ability, they do not form teratoma in vivo, but there exist limitation of cellular source supply. Accordingly, differentiation of hESC into MSC will be promising cellular source with strong points of both hESC and MSC line. In this study, we described the derivation of MSC like cell population from feeder free cultured hESC (hESC-MSC) using direct differentiation system. Cells population, hESC-MSC and bone marrow derived MSC (BM-MSC) retained similar characteristics in vitro, such as morphology, MSC specific marker expression and differentiation capacity. At the point of differentiation of both cell populations, differentiation rate was slower in hESC-MSC than BM-MSC. As these reason, to verify differentially expressed molecular condition of both cell population which bring out different differentiation rate, we compare the molecular condition of hESC-MSC and BM-MSC using 2-D proteomic analysis tool. In the proteomic analysis, we identified 49 differentially expressed proteins in hESC-MSC and BM-MSC, and they involved in different biological process such as positive regulation of molecular function, biological process, cellular metabolic process, nitrogen compound metabolic process, macromolecule metabolic process, metabolic process, molecular function, and positive regulation of molecular function and regulation of ubiquitin protein ligase activity during mitotic cell cycle, cellular response to stress, and RNA localization. As the related function of differentially expressed proteins, we sought to these proteins were key regulators which contribute to their differentiation rate, developmental process and cell proliferation. Our results suggest that the expressions of these proteins between the hESC-MSC and BM-MSC, could give to us further evidence for hESC differentiation into the mesenchymal stem cell is associated with a differentiation factor. As the initial step to understand fundamental difference of hESC-MSC and BM-MSC, we sought to investigate different protein expression profile. And the grafting of hESC differentiation into MSC and their comparative proteomic analysis will be positively contribute to cell therapy without cellular source limitation, also with exact background of their molecular condition.

• 콘크리트학회논문집
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• 제27권1호
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• pp.85-92
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• 2015

콘크리트 내 염소이온은 콘크리트 내부로 침투하여 철근부식을 일으키는 주요 요인이다. 그런데 내재된 염소이온의 일부는 시멘트의 수화물과 반응하여 물리 또는 화학적 흡착을 유발하여 침투속도는 느려진다. 이때 시멘트의 수화물이 염소이온의 고정화에 영향을 미치는 요인이므로, 본 논문은 독립적인 시멘트 수화물에서 염소의 흡착에 대하여 초점을 두어 연구하였다. 본 연구의 목적은 시멘트 수화물이 염소이온을 흡착하는 시간의존적 거동을 고찰하여 염소이온 고정화의 메커니즘을 구명하는 것이다. 시멘트 수화물 중 AFt 상과 CH 상은 염소이온을 흡착하지 못하였으나 C-S-H 상과 AFm 상은 염소 흡착능력을 갖고 있는 것으로 나타났다. 특히, AFm 상은 40일 동안 느린 속도로 화학적 흡착 거동을 보인 반면, C-S-H 상은 순간적 물리흡착, 물리화학적 흡착, 그리고 화학적 흡착의 3단계로 구분되어 순차적인 흡착거동을 보였다. 반응 실험결과를 토대로, C-S-H 상과 AFm 상의 흡착 거동 해석기법이 제안되었다. 본 연구는 염소이온의 도입원에 따른 흡착 메커니즘을 이해를 토대로, 염소이온의 도입원에 따른 염소이온의 침투속도를 산정하는데 활용될 수 있을 것으로 기대된다.

• 가정과삶의질연구
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• 제1권2호
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• pp.43-57
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• 1983

The purpose of the study, was to investigate Housewives behavior on how to buy refrigerators and how to use them. Besides, their knowledge and keeping ability of electricity and refrigerator is estimated according to regional differences, their ages, their educational courses, and their income. In the report, W e can see if it is related to the years of married life, numbers of the family, having jobs or not, and numbers of marketing a week. The subjects were 675 mothers of the students in the selected schools, at Seoul, Cheongjoo, and Kwesan gun. They answered to the questionnaire devised for the study. their answers were analyzed in percent to grasp their general trend of electricity and electric Appliance. Chi-square test and F-test are chosen to grasp the Cor-relationships between the related variables. The results are as follows: 1) The average rate of possesing the refrigerators is 84.06%. It shows us that the housewives in Seoul possess the more refrigerators than those in other areas. At ages, form 30 to 40 aged women gave the most refrigerators than any other ages women. It reveals us the high income and high educational housewives have high rate of possessing refrigerators. 2) They answered that they purchased the refrigerators by necessity. we can see their motivation of purchasing them is very reasonable. However, we can see that they do not manage the refrigerators well, because the rate of using them during four seasons is only 12.34%, An age of 20year old housewives mostly purchased the refrigerators at the time of marriage. The women who bought them after marriage answered that they mostly took a consultation with their husbands when they bought the refrigerators. They regarded the trade marks of the manufactures and size of the refrigerators, as they bought them. And most of them bought the refrigerators for cash. 3)At homes in Seoul, the kinds of retained foods in the refrigerator are more than those of the house in the city and in the agricultural town. The high income and high educational housewives tend to retain the more kinds of foods. But there are no significant differences between the essential variables such as the numbers of the family, the housewives having jobs or not, and the numbers of marketing. 4)Generally their knowledge on electricity and the refrigerator is very low. However, it shows the statistically significant differences. the housewives in Seoul have more information about refrigerator than the housewives in agricultural town. At ages , the women less than 29 years old have more information about the refrigerator, and the woman who had university education and high income tend to know much about the refrigerator. 5) The keeping ability of the refrigerator is very good, and there are no significant differences among variables. And also it shows that there is no correlationship between their knowledge and their keeping ability.

• Journal of Yeungnam Medical Science
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• 제2권1호
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• pp.81-85
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• 1985

저자들은 하부 요관결석에서 경뇨도적배석술의 유용성을 알아보고자 1983년 9월부터 1985년 8월까지 만 2 년동안 영남대학병원 비뇨기과에 입원한 하부 요관결석 환자중 결석의 크기가 1.0cm 이하이며 방광경 조작의 적응이 되는 37명에서 Dormia stone dislodger를 이용한 경뇨도적 배석술을 시행하여 다음과 같은 결과를 얻었다. 1. 37명의 환자중 16명에서 결석이 조작 즉시 배출되었고, 5명에서는 유치한 catheter 제거시 동시에 배출되었으며, 4명에서는 조작후 l 주이내에 자연배출되어 68%의 성공률을 얻었다. 2. 결석의 크기에 따른 성공률은 결석의 장경이 0.4cm 이하인 경우 77%, 0.4~0.6cm인 경우 58%, 0.6cm 이상에서 33%로서 결석의 크기가 작을수록 성공율이 높았다. 3. 합병증으로는 배석기의 파손으로 요관 절석술을 시행한 1례, 요관협착으로 중등도의 수신증이 병발한 1례, 지속적인 혈뇨가 생긴 1례로서 8.1%의 합병증률을 보였다. 이상의 결과로 1.0cm 이하의 하부 요관결석에서 경뇨도적 요관배석술을 시행하여 비교적 높은 성공률과 낮은 합병증률을 보였다. 이에 저자들은 하부 요관결석 환자에서, 특히 결석의 크기가 작고 반복적인 동통이 동반된 경우에는 일차적으로 경뇨도적 요관배석술을 시행해 보는 것이 바람직하다 하겠다.

• 대한환경공학회지
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• 제34권3호
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• pp.195-203
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• 2012

재질별 생물활성탄(BAC) 및 안트라사이트 biofilter에서 EBCT 및 수온변화에 따른 인공사향물질(SMCs) 3종의 생물분해 특성을 조사한 결과 다음과 같은 결론을 얻을 수 있었다. 생물활성탄(BAC) 공정에서 인공사향물질 3종의 제거는 EBCT와 수온에 따라 큰 영향을 받으며, EBCT와 수온이 증가할수록 제거능이 증가하였다. 물질에 따른 제거능은 MK가 가장 높았고 다음으로 HHCB, AHTN 순이었다. 또한, 활성탄 재질에 따른 생물활성탄(BAC) 및 안트라사이트 biofilter에서의 인공사향물질 3종의 제거는 석탄계 재질의 BAC에서 생물분해능이 가장 높았고, 다음으로 목탄계, 야자계, 안트라사이트 순으로 조사되었다. 인공사향물질 3종에 대한 생물분해 속도상수($K_{biodeg}$)와 반감기($t_{1/2}$)는 수온이 $5{\sim}25^{\circ}C$일 때 0.0082~0.4452 $min^{-1}$와 1.56~84.51 min이었으며, 수온이 $15^{\circ}C$와 $25^{\circ}C$로 증가시켰을 때 $5^{\circ}C$에서의 반감기보다 3.1~9.3배 감소되었다.

• 한국초지조사료학회지
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• 제38권4호
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• pp.325-330
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• 2018

본 연구는 퇴비단 내에서 소리쟁이 종자와 피 종자의 발아력 억제효과를 분석하기 위하여 염소 분 퇴비, 젖소 분 퇴비 그리고 한우 분 퇴비를 대상으로 하여 실험을 수행하였다. 소리쟁이 종자와 피 종자를 거즈에 싸서 퇴비단 내에 묻어놓고 1.5일, 3일, 10일, 20일 경과 후 종자를 회수한 뒤 발아력을 측정하였다. 실험 결과 소리쟁이 종자와 피 종자의 발아율은 가축 분의 종류와 퇴비화 방법에 관계없이 퇴비단의 온도와 직접적인 상관관계를 가지는 것으로 나타났다. 온도가 $60{\sim}70^{\circ}C$인 조건의 퇴비단에서 1.5일 동안 머무른 소리쟁이 종자와 피 종자는 발아력을 완전히 상실하였다. 반면에 퇴비단 최고 온도가 $51^{\circ}C$ 이하인 퇴비단에서는 소리쟁이 종자와 피 종자가 퇴비단 내에서 20일간 머무른 후에도 10 % 정도의 발아력을 유지하였다. 이상의 결과를 종합해보면, 소리쟁이 종자와 피 종자의 발아율을 억제하기 위해서는 가축 분 퇴비화단계에서 최소 $55^{\circ}C$ 이상의 온도를 3일 이상 유지하는 것이 좋다. 또한 퇴비단 온도가 $60{\sim}70^{\circ}C$ 정도 상승한다면 약 1.5일 정도 체류하는 것으로도 소리쟁이 종자와 피 종자의 발아력을 억제할 수 있을 것이다. 퇴비화 방법을 기준으로 보면, 호기적 퇴비화 방법이 퇴비단의 온도상승기간이 더 짧았다. 따라서 호기적 퇴비화방법을 적용하는 것이 소리쟁이 종자와 피 종자의 발아력을 억제하는데 더 효율적일 것이다.

• Archives of Reconstructive Microsurgery
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• 제21권2호
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• pp.143-148
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• 2012

Purpose: This report presents the authors' experience of twelve patients with sural artery flap for soft tissue defects around the knee joint. Materials and Methods: The patients' age ranged from 25 to 80 years; seven of the patients were male and five were female. The cause of soft-tissue defects involved wide excision for malignant soft tissue tumor, tumor prosthesis related infection, infection after total knee arthroplasty and chronic osteomyelitis. Postoperative range of motion was checked. The sensibility of flap was evaluated by Semmes-Weinstein monofilaments and two-point discrimination. Results: All flaps survived and provided satisfactory coverage of the defect. There was no complication except one delayed skin graft incorporation at donor site. Seven knee joints which had been stiff previously gained average 58 degrees of ROM postoperatively. All flaps retained sensibility and showed no significant increase in sensory thresholds comparing with contralateral side. Conclusion: Sural artery flap not only shows high survival rate and broad coverage ability, but also offers improvement in range of motion and preservation of sensation. We speculate that sural artery flap is valuable for the reconstruction of the soft tissue defects around knee joint.

• Korean Journal of Acupuncture
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• 제25권2호
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• pp.179-197
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• 2008

Objectives and Methods : The purpose of this study was to observe the effects of acupuncture and electro-acupuncture (EA) at PC6 on intestinal motility in rats. We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat, and carried out acupuncture with needle retained (NR), low frequency (2 Hz) EA and high frequency (100 Hz) EA at PC6 before or after the administration of carbachol or loperamide. The charcoal travel rate was measured to evaluate the intestinal motility. Results : 1. NR showed no significant influences on intestinal motility of rat in normal state. While, 2 Hz EA and 100 Hz EA at PC6 significantly increased the intestinal motility of rat in normal state. 2. All of the pre-treatment and post-treatment of NR, 2 Hz EA and 100 Hz EA at PC6 showed no significant effects on intestinal motility of rat which was over-activated with carbachol. 3. Both pre-treatment and post-treatment of NR significantly increased intestinal motility in rat which was suppressed with loperamide. 4. Pre-treatment of 2 Hz EA and post-treatment of 100 Hz EA significantly increased intestinal motility in rat which was suppressed with loperamide. Conclusions : These results suggest that acupuncture (NR) and EA on PC6 have preventive and therapeutic effect on suppressed intestinal motility, and NR may be more effective than EA in that condition.