• Title/Summary/Keyword: Resveratrol-alginate nano-complex (RANCP)

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Cognitive Improvement Effect of Resplex Alpha A in the Scopolamine-induced Mouse Model

  • Bong-geun Jang;Youngsun Kwon;Sunyoung Park;Gunwoo Lee;Hyeyeon Kang;Jeom-Yong Kim
    • CELLMED
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    • v.13 no.14
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    • pp.14.1-14.9
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    • 2023
  • Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).