• Herbal Formula Science
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• v.25 no.2
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• pp.179-191
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• 2017

Objectives : Increased oxidative stress by reactive oxygen species (ROS) has been suggested as a major cause of muscle fatigue. Although several studies have demonstrated the various biological properties of Sophora flavescens Aiton, Glycyrrhiza uralensis Fischer and Dictamnus dasycarpus Turcz, but the antioxidative potentials have not been clearly demonstrated. The present study was designed to investigate the protective effects of their water and ethanol extract mixtures (medicinal herbal mixtures, MHMIXs) on hydrogen peroxide ($H_2O_2$)-induced cell damage and apoptosis in C2C12 myoblasts. Methods : Cytotoxicity was assessed by an MTT assay. Quantitative evaluation of apoptosis induction and ROS production was evaluated by flow cytometry analysis. Expression levels of apoptosis regulatory and DNA-damage proteins were detected by Western blotting. Result : The inhibition of $H_2O_2$-induced cell proliferation was effectively blocked in extracts of 3: 1: 1 (EMHMIXs-1) or 2: 2: 1 (EMHMIXs-2) of S. flavescens, G. uralensis and D. dasycarpus Turcz, ethanol extracts from various complex extracts in C2C12 myoblasts. EMHMIXs-1 and EMHMIXs-2 also effectively attenuated $H_2O_2$-induced C2C12 cell apoptosis, which was associated with the restoration of the upregulation of Bad and death receptor 4, and downregulation of XIAP and cIAP-1 induced by $H_2O_2$. In addition, these herbal mixtures significantly blocked the $H_2O_2$-induced ROS generation and phosphorylation of $p-{\gamma}H2A.X$, which suggests that they can prevent $H_2O_2$-induced cellular DNA damage. Conclusions : The results suggest that EMHMIXs-1 and EMHMIXs-2 could block the DAN damage and apoptosis of C2C12 myoblasts by oxidative stress through blocking ROS generation.

• Food Science and Preservation
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• v.13 no.2
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• pp.180-185
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• 2006

Prunus mume has been used as a Korean medicine. It is effective in treating diarrhea and an abdominal pain. This experiment was carried out to optimize extraction conditions of prunus mume flower tea and to analyze volatile compounds. Three kinds of samples treated with fresh, freeze dry, and shade dry, were used, and prunus mum flower tea was manufactured by the mixed ratio of green tea and prunus mume flower. The result was valued by the Hunter's value, flavor and taste. The optimum conditions of extraction time and temperature were 3 min and $80^{\circ}C$ respectively. Sensory evaluation shows that optimum ratio was adaptive 90% green tea with 10% prunus mume flower. The major volatile compound in prunus mume flower was benzaldehyde.

• Korean Security Journal
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• no.14
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• pp.449-464
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• 2007

The Guard might focus on a king's personal safety in the wake of the system of the Silla and Taebong dynasties until the establishment of the Goryeo Dynasty's unique political system. The purpose of this research is to examine gob characteristics and organizational effectiveness of security guard on martial arts of security service guard. The subjects of this study are private guard as working security companies of Seoul and Kyongi area and 250 persons. It was a method of questionnaire for this study and used a questionnaire developed by Hackman and Oldham(1976) for gob characteristics and used a questionnaire developed by Tymon(1988) for organizational effectiveness that translated and modified from Kim, Ilsoon and measured by 5 point likert. It used to analyze the data for one-way ANOVA and multiple regression analysis. There are conclusions of this study. First, there was a partially difference on god characteristics and organizational effectiveness of population statistical character. Depending on sex, 'female' group was high, depending on the age, '46 year-old+ group' was high, depending on the educational level, 'bachelor group' was high, depending on the income, '400manwon+ group' was high. Second, it becomes positive result to the period, the frequency and the intensity of security martial arts practice. Third, it happened that gob characteristics is increase and organizational effectiveness is also positive way.

• Journal of the Korea Society for Simulation
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• v.24 no.4
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• pp.1-9
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• 2015

As the use of software is more wider in the safety-critical nuclear fields, so study to improve safety and quality of the software has been actively carried out for more than the past decade. In the nuclear power plant, nuclear man-machine interface systems (MMIS) performs the function of the brain and neural networks of human and consists of fully digitalized equipments. Therefore, errors in the software for nuclear MMIS may occur an abnormal operation of nuclear power plant, can result in economic loss due to the consequential trip of the nuclear power plant. Verification and validation (V&V) is a software-engineering discipline that helps to build quality into software, and the nuclear industry has been defined by laws and regulations to implement and adhere to a through verification and validation activities along the software lifecycle. V&V is a collection of analysis and testing activities across the full lifecycle and complements the efforts of other quality-engineering functions. This study propose a methodology based on V&V activities and related tool-chain to improve quality for software in the nuclear power plant. The optimized methodology consists of a document evaluation, requirement traceability, source code review, and software testing. The proposed methodology has been applied and approved to the real MMIS project for Shin-Hanul units 1&2.

• Journal of the Korea Society of Computer and Information
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• v.20 no.2
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• pp.99-112
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• 2015

Datum point for displaying location and altitude of point has being advantage usefully in various measurement parts. However, datum point has been increasing loss cases owing to weather changes and stratum changes and neglecting meaninglessly. In this paper, we design and implement a multi electronic measurement system monitoring software with functions such as include maximize utilization of existing measurement datum system as well as collected various environment data and detection stratum changes of surround area. Proposed software is implemented to support that reusability and extensibility of software using object oriented modeling method. Our software supports a GUI for electronic measurement datum point administrator as well as for web user and mobile user. Our system can support a graph GUI for various data analysis and reposition in realtime to database that measured location information and various sensing information to prevent loss of electronic measurement datum point and to detected stratum changes. In addition, we include a QR code and RFID recognition function. Finally, we suggest performance evaluation result to confirm stratum changes detection and GPS location error rate.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.5
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• pp.858-864
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• 2001

This study was performed to investigate the effect of sodium lactate (SL, 60%) and a mixed fat replacer (FR) on the product quality and shelf-life effect of low-fat bologna sausage (LFBS) in a model system during refrigerated storage. Low-fat and regular-fat bologna sausages had pH values ranged from 6.15 to 6.30 and water activity values ranged from 0.95 to 0.96. LFBS had a moisture content of 74~76%, <2% fat and 14~15% protein, whereas regular-fat bologna had 60% moisture, 22% fat and approximately 12% protein in the final products. Expressible moisture (%) increased (p<0.05) in all bolognas, resulting in the soft texture, as the storage time (weeks) increased. LFBS manufactured with SL and a FR had lower (p<0.05) the cooking loss (%) and had higher (p<0.05) texture profile analysis (TPA) values than the regular-fat counterpart. As the sodium lactate level increased up to 5% in the formulation of LFBS, vacuum purge and TPA hardness values also increased (p<0.05), but thiobarbituric acid (TBA) values decreased (p<0.05). Total plate counts of LFBS were reduced (p<0.05) when the addition level of 60% SL solution was more than 3.3%. This result indicated that the increased level of SL (>3.3%) in the combination of a FR in the formulation of LFBS improved the product quality and did inhibit the total microbial growth of LFBS during storage, as compared to the control.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.55 no.2
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• pp.121-128
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• 2019

Various artificial reefs provide the fish habitat and nursery, and contribute the improvement of fisheries productivity. The evaluation methods of fishery resources in the artificial reefs have been done by fishing, scuba diving, underwater camera, and scientific echo sounder/sonar. There are a number of studies using echosounders on the quantitative and qualitative evaluations of artificial reefs in various seas around the world. This study focused on the spatial distribution of fishes around artificial reefs and the influential area of reefs off Bukchon, Jeju Island. Not only acoustic data but also various properties of artificial reefs were used in the geographic information system to extract relevant results. As a result, the major material of reefs on this study site was concrete and the number of reefs with that material was the most. The volume of reefs consisted of steel only and steel with riprap was considerably large compared to other reefs. The average NASC in the vertical distribution of fishes in artificial reefs was $31.6m^2/nm^2$ in April, and that was $61.3m^2/nm^2$ in June. The distance between the fish school and their nearest reef in June morning had a wide range from 750 to 3250 m. On the basis of the influence ray of artificial reefs, it had a tendancy of NASC to decrease with distance from the reef in the June morning. It is a preliminary study to present the geospatial analysis example to understand a better way of comprehensive artificial reef environments.

• Journal of Environmental Impact Assessment
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• v.31 no.3
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• pp.129-140
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• 2022

Environmental impact assessment on development projects is a process in which various stakeholders derive consultations by reflecting project characteristics and regional environmental status, and implementation of consultations is a prerequisite for securing sustainability of the local environment. The business plan can be changed to respond to changes in social and environmental conditions. And the business plan for which the environmental impact assessment consultation has been completed, it can be changed as a systematically prepared procedure (called Consultations on Amendment). As a result of investigating and analyzing the current status and major changes in the development project, Consultations on Amendment in industrial complexes were the most common, and the environmental impact is increasing accordingly. As the results of the analysis of operational status and the case studies, the main causes of Consultations on Amendment in industrial complex can be summarized into three categories: (1) formal demand forecasting for tenant industries, (2) excessive omission and simplification of administrative procedures under the Special Act, and (3) the use of an expedient change consultation system to facilitate environmental impact assessment consultation and shorten the period. This study proposes the following three measures to prevent the deterioration of the environmental impact assessment function due to frequent consultations on industrial complex changes; (1) Ensuring residents' participation procedures for Consultations on Amendment that changes important matters, (2) Reasonable revision of the "Simplification of Industrial Complex Procedures Act" to enhance the feasibility of industrial complex development plans and locations, (3) Development of evaluation criteria and methods for verification of real demand for objective demand management for industrial complexes, and (4) Preparation of a review guideline for Consultations on Amendment.

• Korean Journal of Heritage: History & Science
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• v.56 no.1
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• pp.100-116
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• 2023

The Sinamsa Temple was built in the late Goryeo Dynasty and a gilt-bronze seated Buddha is enshrined in Geungnakjeon hall in the precinct. Various damages occurred in the gilt layer of the Buddha, such as peeling of the gilt layer and deteriorating gloss. In the study, the conservation conditions of the inside and outside on the statue were accurately investigated, and the making technique was interpreted through the material characteristics and non-destructive diagnosis of the statue. As a result, it is estimated that gold-gilding layer is pure gold, coloration pigment of black is carbon, green is malachite, atacamite and verdigris, red is red lead and cinnabar, respectively. In the deterioration evaluation, peeling, cracking, break out and exfoliation of the gilt layer are confirmed as damages, but the conservation condition is relatively wholesome. However, the gloss of the gilt layer is calculated to be wider in the poorer part than the maintenance part. The ultrasonic velocity of the statue was calculated to be 1,230 to 3,987 (mean 2,608) m/s and showed a relatively wide range. In infrared thermography, peeling was not confirmed, and no special bonding marks were found. In endoscope, some biological damage and corrosion were observed on the surface of the internal metal, and sealed artifacts were identified. Manufacturing technique based on the study, it is considered that the gilt-bronze seated Buddha was cast at once, and the mold was inverted to inject molten metal.

• Journal of the Korea Convergence Society
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• v.8 no.1
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• pp.131-138
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• 2017

The purpose of research and bamboo for failure, Damyang-county, Jeollanam-do at 2015 Damyang bamboo the world fairs held according to the attachment to local factors impact of regional development and hosting support. To identify the impact on the property held. Fair after setting up a hypothesis to carry out research in the visitors through after sample surveys and survey and Empirical Analysis. Show areas are improving in the future, due to host tourists want to come up with the purpose of research to become a popular tourist attraction again. Attachment or environmental factors and social factors showed that, and affect the region. The host of social factors turned out to be the biggest influence, and economic factors, environmental factors shown to affect, and to a venue in order.Attachment is a factor appears to be affecting the region was the venue. The property is shown to environmental factors is not statistically significant, and host local affection, support appears to be factors affecting the holding. As a result, Fair, held regional attachment to the Influence Factors of regional development support, and according to the next fair in the Region and through the impact on the property held.Evaluation strategy could contribute to explore the festival.