• Title/Summary/Keyword: Resting pressure

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Effects of Intermittent Hydrostatic Pressure on the Cell Adhesive force on the substrate (간헐적 정수압이 세포의 부착에 미치는 영향성 평가)

  • Kim Young-Jick;Lee Myung-Kon;Park Su-A;Shin Ho-Joon;Kim In-Ae;Lee Yong-Jae;Shin Ji-Won;Shin Jung-Woog
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.69-72
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    • 2005
  • In this study, effects of IHPs with various resting times to cell adhesion were investigated through the measurements of cell adhesive force, number and area of focal contacts (stained vinculin spots), and projected cell area, perimeter and circularity. In addition correlation tests and curve estimations using the experimental results were performed fur the finding an essential factor for increment of cell adhesive force. Tn the results, immediately after mechanical stimuli (150 minutes after seeding) and one hour later (210 minutes after seeding), the average adhesive force of experimental group 5 (resting time: 15min) compared with that of control group at same culture time was increased significantly (p<0.05). Average projected area and perimeter of cells at Group 5 were increased significantly (p<0.05), while average circularity of cells at Group 5 incubated fur 210 minutes was decreased significantly (p<0.05). In the digital image analysis of focal contacts containing vinculins, area and numbers of focal contacts per cell at Group 5 were higher than those of the other groups. This study indicated that IHP with appropriate resting time could contribute in improving cell adhesive force, cell spreading, development of cytoskeleton and formation of focal contacts. And cell adhesive force was correlated to the morphological aspects of cell and development of focal contacts. Particularly, area of focal contacts was closely related to cell adhesive force.

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Mechanical analysis of functionally graded spherical panel resting on elastic foundation under external pressure

  • Cao, Yan;Qian, Xueming;Fan, Qingming;Ebrahimi, Farbod
    • Structural Engineering and Mechanics
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    • v.74 no.2
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    • pp.297-311
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    • 2020
  • The main purpose of this study is to analyze the effects of external pressure on the vibration and buckling of functionally graded (FG) spherical panels resting of elastic medium. The material characteristics of the FG sphere continuously vary through the thickness direction based on the power-law rule. In accordance with first-order shear deformation shell theory and by the use of Ritz formulation the governing equations are presented. In this regard, the beam functions are applied in two-dimensions for different sets of boundary supports. The Winkler and Pasternak models of elastic foundations are also taken into account. In order to show the validity and applicability of the presented formulation, various comparison studies are given. Furthermore, a diverse range of numerical results is reported to check the impacts of geometrical and material parameters along with external pressure on the vibration and buckling analysis of FG spherical panels.

Effect of Lifestyle Modification Program on Blood Pressure Improvement in Patients with Hypertension (고혈압 환자에서 생활습관 개선 프로그램의 혈압개선효과)

  • Lee, Sang-Uk;Oh, Chang-Mo;Oh, In-Hwan;Yoon, Tai-Young;Choi, Joong-Myung
    • Korean Journal of Health Education and Promotion
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    • v.27 no.4
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    • pp.105-112
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    • 2010
  • Objectives: The purpose of this study was to know different effect with uncontrolled hypertension patients after providing health promotion program which consisted with medicine, exercise, nutrition. Methods: The subjects of this study was comprised by uncontrolled hypertension patients in spite of medication and didn't care the pressure by medication. The health promotion program was progressed by group exercise three times a week, nutrition education once a week and medical consultation once a month for 12 weeks. Subjects were measured for body composition(weight, fat mass, % body fat and body mass index), hemo-dynamics(systolic blood pressure(SBP), diastolic blood pressure(DBP), and resting heart rate), and physical fitness (cardiopulmonary endurance, muscular strength, muscular endurance, balance, and flexibility). Results: Groups showed significant improvement in every measure except resting heart rate. SBP is decreased both taking drug group about 18.4mmHg and without taking drug group about 19.4mmHg.(p<0.001) DBP is decreased both taking drug group about 8.7mmHg and without taking drug group about 9.0 mmHg.(p<0.001) Conclusion: There are no statistical significant differences of SBP and DBP decreasing effects by medication, Since effects of decreasing pressure are not different by medication, I think the health promotion program is effective to uncontrolled hypertension patients to decrease pressure.

A Study on Nutritional Management for Improvement of Exercise Capacity and Physical Fitness -For Dietary Feeding Condition- (운동 수행 능력 및 체력증진을 위한 효율적 영양관리에 관한 연구 -식이급식 조건에 대하여-)

  • 오승호;김유섭;강정채
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.2
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    • pp.94-102
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    • 1991
  • This study was directed to further clarify the effect of resting time or dietary condition for the improvement of exercise capacity and physical fitness, and the changes of some body consitiuents and physiological functions which are related to the exercise metabolism. Sixteen male students(8 athletes and 8 nonathletes)were participated during 3 weeks(Aug. 20-Sep.9, 1989). Each subject performed two treadmill running trials at an absolute intensity (1 mintute in 3.4mph/15% slope and 2 minutes in 5.5mph/20% slope). In the resting time trials, general diet was fed before 1, 2, 4 and 12 hours of the treadmill exercise loaded. in the dietary condition trials, high carbohydrate(HC), high fat(HF) and high protein(HP) diet were fed before 2 hours of the treadmill exercise loaded. Control trial was that of resting time before treadmill exercise loaded after 12 hours of general diet feeding. Measurement were made to study the change of blood glucose, palmitate, lactate, blood pressure and heart rate. The results obtained are summarized as follows: Mean daily metabolizable period. In resting time trial, the blood glucose concentration of athlete and nonathlete from 2 hours group was similar to control group. The blood palmitate concentration of athlete was increased in 1 and 2 hours group but those of nonathlete was not only increased in 1 and2 hours group but was more increased in 12 hours group, compared with both control group. The blood lactate concentration was increased in all experimental group, compared with both control group and those of nonathlete was much higher than athlets. The elevation rate of blood pressure in pre-and after-exercise of athlete was lower than those of nonathlete. In dietary composition trial, the blood glucose concentration of athlete and nonathlete in HC group was higher than other diet groups. The blood lactate concentration of athlete and nonathlete in HC group was lower than other diet groups. There was no remarkable change of the blood palmitate concentration and heart rate in each dietary composition trial, but those of nonathlete was low in HC and high in HP group. In above results, it was suggested that the effective condition of resting time and dietary composition for the improvement of exercise capacity of nonathlete may be 2 hours and HC diet, respectively. But it was showed that the exercise capacity of athlete may not be affected by experimental condition of resting time, except 1 hour after feeding or of dietary composition because of well adaptation in new exercise condition.

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Effects of Personalized Complex Aerobic Training Programs using Wearable Device on Cardiovascular and Respiratory Functions of Female Elderly

  • Song, Jun-Young;Park, Sam-Ho;Kim, Byeong-Soo;Ha, Tae-Won;Son, Jin-Kyu;Lee, Myung-Mo
    • Physical Therapy Rehabilitation Science
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    • v.10 no.4
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    • pp.421-429
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    • 2021
  • Objective: The purpose of this study was to examine the effect of personalized complex aerobic training programs using wearable device on cardiovascular and respiratory functions in community based female elderly. Design: One group pre-post intervention study. Methods: Twenty-one older female participants lived in 'D' city were included. The personalized complex aerobic training program using wearable devices was applied to all participants for 4 weeks, 3 times a week, 30 minutes for per session. The participants' blood pressure, heart rate, oxygen saturation, respiration rate, submaximal exercise stress test, pulmonary function test and respiratory muscle strength test were evaluated before and after the complex training program. Results: After intervention, resting diastolic blood pressure, resting systolic blood pressure and the systolic blood pressure after submaximal exercise stress test were significantly decreased over time (p<0.05), and the submaximal exercise stress test duration were significantly increased over time (p<0.05). The maximal inspiratory pressure (MIP) was significantly increased compare to before the intervention (p<0.05). Conclusions: This study showed that personalized complex training program using wearable device can provide personalized exercise intensity according to cardiopulmonary function that give feedback, and these interventions have a significant effect on improving the cardiovascular and respiratory system functions of the female elderly in the community dwelling.

Changes in Water and Electrolyte Distribution and Blood Glucose Concentration following Irreversible Hemorrhagic Shock (비가역성 실혈성 쇽에서 본 가토심근, 혈장의 전해질 및 혈당량 변화)

  • Kim, Ki-Whan;Nam, Kee-Yong
    • The Korean Journal of Physiology
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    • v.2 no.1
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    • pp.47-52
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    • 1968
  • Twenty white rabbits anesthetized with nembutal (30 mg/kg) were employed in this experiment. Five of them served as controls; the remaining rabbits as experimental group were subjected to irreversible hemorrhagic shock. Shock was induced by bleeding the animals until mean blood pressure decreased to a level of 50-40 mmHg. This level of pressure was maintained for 3-4 hours, after which the drawn blood was reinfused. The reinfusion of blood caused the elevation of arterial pressure almost the control level for some minutes, after which a gradual and progressive decline of blood pressure became evident. This decline was thought to be the result from irreversible hemorrhagic shock. When mean blood pressure declined to less than 50 mmHg, chest was opened and samples of arterial blood and left ventricular muscle were taken. Left ventricular muscle and blood plasma were analyzed for potassium, sodium, chloride and water content. Blood glucose concentration was determined by Somogyi-Nelson's method. Extracellular and intracellular myocardial water and electrolyte content were calculated on the basis that electrolytes are distributed between plasma water and interstitial water according to Gibbs-Donnan equilibrium. In this calculation extracellular water was substituted for Na space. The findings obtained were as follows: 1. The concentration of blood glucose was 87mg% in the controls and it rose to 222 mg% in shock (P<0.01). 2. Plasma potassium elevated significantly from 3.3 mEq/l in controls to 8.0 mEq/l in shock (P<0.01), while small decreases in sodium (151-146 mEq/l) and chloride (102-96 mEq/l) were observed (P<0.3, P<0.1), 3. The changes of blood water content (83.1-84.3%) and cardiac water content (77.5-78.3 gm/100gm WT) were observed. 4. In control animals myocardial potassium levels which averaged 30.2 mEq/100 gmDT rose significantly to 40.3 mEq/100 gmDT in shock (P<0.01), while moderate decreases in sodium(16.3-14.3 mEq/100 gmDT) were observed in shock. 5. The calculated transmembrane resting potential of left ventricular muscle of control animals averaged 95 mV, while rabbits in shock averaged 77 mV. (P <0.01). The findings of this experiment do not correspond with the conclusions that myocardial depression seems to be the cause of irreversible hemorrhagic shock, because the excitability of heart muscle is elevated. From the point of view that the lowered transmembrane resting potential, the cause of death in terminal stage of irreversible hemorrhagic shock may be ventricular fibrillation. It can't be said, however, that the lowered transmembrane resting potential is responsible for the transition from reversible to irreversible hemorrhagic shock. The marked increase in blood glucose suggested that glycogenolysis in the liver is favorably active in shock.

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An Analysis of the Farm Silo Supported by Ground (지반과 구조물 사이의 상호작용을 고려한 농업용 사이로의 해석에 관한 연구(IV) -제 4 보 관행설계법과의 비교)

  • 조진구;조현영
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.30 no.2
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    • pp.44-54
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    • 1988
  • This study was carried out to investigate the applicability of the conventional design method for ground supported circular cylindrical shell structures. For this purpose, the ensiled farm silo was adopted as a model structures. Herein, the conventional design method was based on the assumption that such structures are clamped at the bottom edges or the ground pressure is independent of the deflection at the surface. In the present paper, the applicability of above assumption was checked out by comparison with an exact method considering soil-structure interaction. Some results of numerical calculation show us ; When the ground is very hard, for example Winkler's constant k is larger than 100 kg / cm$^2$ / cm, or the bottom plate of structures has a infinitely stiffness, for example the bottom plate thickness is larger than 100 cm, the sectional forces, obtained from the conventional method at any wall of structures resting on an elastic foundation, can used for design purpose. Therefore, if the above condition is satisfied then the conventional assumptions can be justified for the design purpose. In this case, the assumption that such structures are fixed at the lower edges was more realistic than the assumption that the reaction pressure acting on structures is uniformly disributed since the accuracy of results of the analysis by the former assumption was higher than that obtained from the latter assumption. But the sectional forces in the bottom plate resting on ground directly could not be evaluate correctly by the conventional method.

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Pressure-settlement behavior of square and rectangular skirted footings resting on sand

  • Khatri, Vishwas Nandkishor;Debbarma, S.P.;Dutta, Rakesh Kumar;Mohanty, Bijayananda
    • Geomechanics and Engineering
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    • v.12 no.4
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    • pp.689-705
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    • 2017
  • The present study deals with the Pressure-settlement behavior of square and rectangular skirted footing resting on sand and subjected to a vertical load through a laboratory experimental study. A series of load tests were conducted in the model test tank to evaluate the improvement in pressure-settlement behavior and bearing capacity of square and rectangular model footings with and without structural skirt. The footing of width 5 cm and 6 cm and length/width ratio of 1 and 2 was used. The relative density of sand was maintained at 30%, 50%, 70%, and 87% respectively. The depth of skirt was varied from 0.25 B to 1.0 B. All the tests were carried out using a strain controlled loading frame of 50 kN capacity. The strain rate for all test was kept 0.24 mm/min. The results of present study reveal that, the use of structural skirt improves the bearing capacity of footing significantly. The improvement in bearing capacity was observed almost linearly proportional to the depth of skirt. The improvement in bearing capacity of skirted footings over footing without skirt was observed in the range of 33.3% to 68.5%, 68.9% to 127% and 146.7% to 262% for a skirt depth of 0.25 B, 0.50 B and 1.0 B respectively. The skirted footings were found more effective for sand at relative density of 30% and 50% than at relative density of 70% and 87%. The bearing capacity was found to increase linearly with footing width for footings with and without skirts. This observation was found to be consistent for footings with different skirt depths and for relative density of sand i.e., 30%, 50%, 70%, and 87%. The obtained results from the study for footing with and without skirts were comparable with available solutions from literature.

Development of Tight-fitting Upper Clothing for Measuring ECG -A Focus on Weft Reduction Rate and Subjective Assessment- (심전도 측정을 위한 밀착 의복 연구 -패턴 축소 및 주관적 평가를 중심으로-)

  • Jeong, Yeonhee;Yang, YoungMo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.11
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    • pp.1174-1185
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    • 2012
  • This study develops tight-fitting upper clothing to measure electrocardiography (ECG) data. Taking into consideration the elasticity of the clothing, we made 4 experimental clothes by applying to each a weft reduction rate of 40%, 50%, 60%, and 70%. The 4 experimental clothes were used to measure resting ECG, exercise ECG, and post-exercise ECG for 4 men in their 20s. We compared clothing pressures using sensors on the human body and on a dressform. Subjective wear sensations of the 4 experimental clothes were evaluated using a subjective 7-point scale (with 7 being most excellent). We measured clothing pressures by using the air type pressure (AMI 3037-2) for upper and lower chest sensors in the developed tight-fitting upper clothing. The lower chest sensor showed that the clothing pressure on a human body and dressform changed consistently as the weft reduction rate decreased. The upper chest sensor showed inconsistent changes in clothing pressure as the weft reduction rate decreased. The wearing-test result for preliminary subjects showed that the lower chest sensor was more stable than the upper chest sensor; therefore, we inserted the sensor at the lower chest position before performing ECG. Except for Subject 4, the resting ECGs were stably measured for 3 subjects (Subject 1, Subject 2, and Subject 3) in all the developed clothes (A clothing, B clothing, C clothing, and D clothing). However, D clothing showed stable ECG values after exercise. The results of the experiment showed that we could measure ECG without difficulty using clothes with a weft reduction rate of 40% when the movement was not intense; however, tight-fitting upper clothing with a weft reduction rate of 70% was necessary to measure exercise ECG and post-exercise ECG values.

Analytical solutions for geosynthetic tube resting on rigid foundation

  • Guo, Wei;Chu, Jian;Yan, Shuwang;Nie, Wen
    • Geomechanics and Engineering
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    • v.6 no.1
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    • pp.65-77
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    • 2014
  • Geosynthetic tubes inflated with water, clay slurry or sand have been widely used for large dike construction in land reclamation projects. In this paper, analytical solutions for geosynthetic tube resting on rigid foundation is presented by adopting an approach similar to that presented by Leshchinsky et al. (1996). The proposed method allows a quick preliminary design to be made for using a closed-form solution. To simplify the analysis, relationships between geometrical parameters and pumping pressure are established using numerical method. The analytical solutions were compared with several existing solutions and good agreements were achieved.