• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.2
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• pp.127-140
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• 2011

Objectives: Acupuncture has been shown to relieve pain and modulate biological function by stimulating the organ-specific meridians and enhances parasympathetic activity and suppresses sympathetic activity. The aim of this review is to summarize and understand the effects of acupuncture on autonomic nervous system. Methods: We reviewed a total of 29 studies published from 2000 to 2010 searched by PueMed and various domestic oriental medicine journals to obtain acupuncture studies related with ANS. Each article was classified by ANS measurement index and reviewed for study objectives, outcomes, acupuncture points, experimental and control interventions. Results: In the study of acupuncture about EEG, HRV, SCR, the experiment results are not the same by acupoints. Although same acupoint the results differ by subject's condition. But the study showed some clear tendency. In brief, in normal states acupuncture enhanced either vagal or sympathetic tone depending on the stimulated acupuncture point sites. On the other hand, most of studies demonstrated that acupuncture restored the autonomic dysfunctions in various kinds of tired or stressful states. Conclusions: We reviewed studies that contributed to an understanding of the effects and mechanisms of acupuncture on autonomic nervous system. Although the relationship between acupuncture and ANS response is still uncertain, acupuncture could be a excellent treatment method for modulating autonomic dysfunction.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.370-379
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• 2000

Autonomic responses were analyzed in 323 college students exposed to visual stimulation with Korean Affective Picture System (KAPS). Cardiac, vascular and electrodermal variables were recorded during 30 sec of viewing affective pictures. The same slides intended to elicit basic emotions (fear, anger, surprise, disgust, sadness, happiness) were presented to subjects in 2 trials with different experimental context. The first time slides were shown without any instructions (passive viewing), while during the second with instruction to exert efforts to magnify experienced emotion induced by pictures (active viewing). The aim of the study was to differentiate autonomic manifestations of emotions elicited by KAPS stimulation and to identify the role of instructed emotional engagement on physiological response profiles. The obtained results demonstrated reproducibility of responses in both trials with different contexts. Pairwise comparison of physiological responses in emotion conditions revealed the most pronounced differentiation for "ear-anger" and "fear-sadness" pairs (in electrodermal and HR variability parameters). "Fear-surprise" pair was also well differentiable. The typical response profile for all emotions included HR acceleration (except happiness and surprise), an increase of electrodermal activity, and a decrease of pulse volume. Higher cardiovascular and electrodermal reactivity to fear observed in this study, e.g., as compared to data with IAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS in producing certain emotions such as fear in Koreans.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.2B
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• pp.232-243
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• 2010

In this paper, various physiological signals of humans were measured and analyzed to inference their psychological state and biological information, and Bio-Signal Context aware system (BSC), which recognizes the current context of its users as well as the information of exterior environment and offers the service appropriate for them, was designed and implemented. The BSC extracts and analyzes the features from bio-signals, such as the measured electroencephalogram (EEG), electrocardiogram (ECG), and galvanic skin response (GSR), with its different sensors, has the input of the analyzed results, and discriminates four psychological states of rest, concentration, tension and melancholy. In addition to the results of the discriminated psychological states, the information of biological condition analyzed from the user's bio-signals, for example, heart rate variability (HRV), Galvanic skin response (GSR) and body temperature, and the information of external environment related to the user's are collected to offer the service fit for the user's present biological condition by inferring and recognizing the user's present situation.

• Earthquakes and Structures
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• v.11 no.6
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• pp.1027-1041
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• 2016

Different incident angles of ground motions have been considered to evaluate the relationship between floor rotation and torsional irregularity coefficient. The issues specifically addressed are (1) variability in torsional irregularity coefficient and floor rotations with varying incident angles of ground motion (2) contradictory relationship between floor rotation and torsional irregularity coefficient. To explore the stated issues, an evaluation based on relative variation in seismic response quantities of linear asymmetric structure under the influence of horizontal bi-directional excitation with varying seismic orientations has been carried out using response history analysis. Several typical earthquake records are applied to the structure to demonstrate the relative variations of floor rotation and torsional irregularity coefficient for different seismic orientations. It is demonstrated that (1) Torsional irregularity coefficient (TIC) increases as the story number decreases when the ground motion is considered along reference axes of the structure. For incident angles other than structure's reference axes, TIC either decreases as the story number decreases or there is no specific trend for TIC. Floor rotation increases in proportion to the story number when the ground motion is considered along reference axes of structure. For incident angles other than structure's reference axes, floor rotation either decreases as the story number increases or there is no specific trend for floor rotation and (2) TIC and floor rotation seems to be approximately inversely proportional to each other when the ground motion is considered along reference axes of the structure. For incident angles other than structure's reference axes, the relationship can even become directly proportional instead of inversely proportional.

• Ocean and Polar Research
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• v.34 no.3
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• pp.305-323
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• 2012

The ocean's response to the Pinatubo and 1259 volcanic eruptions was investigated using an ocean general circulation model equipped with an energy balance model. Volcanic eruptions release gases into the atmosphere which increases the aerosol optical depth and acts to reduce the incoming short-wave radiation. For example, there was a huge volcanic eruption (Pinatubo) in 1991 which reduced the global mean radiative forcing by about 3 W $m^{-2}$. Two numerical experiments were simulated. The first experiment features the Pinatubo eruption and the second experiment simulates the much larger volcanic eruption that occurred in 1259 when the radiative forcing was reduced by 7 times compared to the Pinatubo event. With the reduced radiative forcing due to the Pinatubo eruption at about 3 W $m^{-2}$ and 1259 eruption at about 21 W $m^{-2}$, the global mean sea surface temperature (SST) decreased to its lowest in the second year after each event by about $0.4^{\circ}C$ and $1.6^{\circ}C$, respectively. Sea surface salinity (SSS) increased substantially in the northern North Pacific, northern North Atlantic, and the Southern Ocean. The reduced SST together with SSS increased ocean convection, which yielded an increase in North Atlantic Deep Water, Antarctic Bottom Water, and North Pacific Intermediate Water production and their outflows. The increase in overturning circulation eventually increased the pole-ward ocean heat fluxes. In conclusion, huge volcanic eruptions perturb the ocean substantially and their hallmarks last for more than a decade, confirming the importance of volcanic eruptions in illustrating the decadal-climate variability recorded in the paleoclimate proxy data for the past million years.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.11a
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• pp.73-80
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• 2000

The paper is addressed to the topic of physiological response-specificity in disgust induced by visual stimulation. The purpose of this study was to evaluate reproducibility of physiological reactivity pattern during disgust elicited by the International Affective Pictures System (IAPS) in 2 experiments. Twenty-nine subjects participated in the first experiment with 3 visual stimulation sessions with disgust-eliciting slides (3 slides in each 1 min long session). In the second experiment disgust-eliciting slides from the IAPS were presented to 42 subjects in 2 sessions (one slide for 1 min). Spectral power of frontal EEG, skin conductance (SCL, SCR and NS.SCR), heart rate(HR), heart period variability(HPV) and respiration rate were recorded. Visual stimulation evoked 1:.n deceleration, higher power of high frequency component of HPV, increased SCL and NS.SCR frequency, frontal slow alpha blocking and moderate increase in fast beta power in most of the sessions in both experiments. However in the second experiment the EEG pattern associated with disgust showed inconsistent shifts in fast alpha and slow beta bands, but was marked by higher power of theta activity. Our data in both experiments emphasizes presence of disgust-specific profiles of autonomic and at the less extent EEG responses in visual stimulation context. Discussed are potential behavioral mechanisms leading to observed physiological manifestations in disgust elicited by visual stimulation. The results support the consideration that disgust is an withdrawal type negative valence emotion associated with relatively low autonomic arousal (low HR, low amplitude SCRs with relatively high NS.SCR frequency) and moderate EEG activation signs. Obtained data showed more consistent reproducibility of disgust-specific autonomic rather than EEG response patterns during visual stimulation design.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.1
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• pp.147-158
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• 2000

For the large scale reinforced concrete cooling tower shells, the shape imperfection can be introduced due not only to mistakes in the process of construction but also to the long term behavior of concrete. The shape imperfection evokes the additional responses such as displacements and stresses in addition to the design values. In this study, the statistical behavior of the RC cooling tower shell due to the shape imperfection is investigated using the Monte Carlo simulation. The radius of cooling tower and the shell thickness are adopted as the parameters which cause the shape imperfection. The shape imperfection is modeled as a stochastic field rather than the local one of axisymmetric or bulge type of imperfection. The randomness in the radius is shown to be more affecting the structural responses than the randomness in the shell thickness. In addition to the geometrical randomness, the effect of randomness in the modulus of elasticity on the structural response is also investigated and compared with that of the geometrical ones.

• The Journal of Korean Medicine
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• v.26 no.1 s.61
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• pp.123-133
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• 2005

Objective : We investigated the sasang constitutional difference of physiological and psychological response in various thermal environmental conditions. Methods: Among 210 volunteers, 30 healthy subjects were selected through the QSCC II (a questionnaire for constitutional discrimination) and the manual examination of a specialist in sasang constitution. Subjects consisted of 10 each Soyang(少陽), Soeum(少陰), and Taeum(太陽). Experimental environments were set by six different conditions to be $23^{\circ}C,\;50\%\;RH,\;0.lm/s;\;25^{\circ}C,\;25\%\;RH,\;0.lm/s;\;25^{\circ}C,\;50\%\;RH,\;0.lm/s;\;25^{\circ}C,\;50\%\;RH,\;0.4m/s;\;25^{\circ}C,\;75\%\;RH,\;0.1m/s;\;and\;27^{\circ}C,\;50\%\;RH,\;0.1m\s$ (respectively temperature, relative humidity, and wind velocity). Skin temperature, core temperature, heart rate variability (HRV), and galvanic skin response (GSR) were measured for each subject Additionally, subjects were asked about comfort through the questionnaire. Results: From the viewpoint of external temperature sensibility, in all experimental environments, generally the Taeum type feels hotter and the Soeum feels colder than other types. In relative comfort, Soeum types were most sensitive to wind velocity change. From the viewpoint of body temperature, Taeum type was lower and Soyang was higher than other types. The measurements of HRV and GSR showed no difference between the types. Conclusion : The four sasang constitution types showed different responses to various thermal environmental conditions. Accordingly, our research could provide basic data for building the optimal thermal conditions for individuals based on sasang constitution. Consequently, it will help to build a healthy environment for everyday life.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.402-407
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• 2019

Background: To investigate the neurobiological evidence supporting the adaptogenic effects of Korean Red Ginseng in reducing the harmful consequences of stress using a double-blind, placebo-controlled trial. Method: Sixty-three subjects with high stress levels were randomized to receive an orally administered, double-blind, 6-week treatment with Korean Red Ginseng (n = 32) or placebo (n = 31). All participants underwent a comprehensive psychological evaluation using Beck Depression Inventory and Stress Response Inventory, cognitive evaluation using the continuous performance test, biological evaluation by measuring blood levels of lipids, catecholamines, inflammation markers, and heart rate variability at baseline and after 6 weeks. Results: At baseline, both groups showed no significant differences in age, sex, years of education, Beck Depression Inventory, and Stress Response Inventory. After 6 weeks, triglyceride levels were significantly increased within the normal limit in the Korean Red Ginseng group (F = 4.11, p = 0.048), and the epinephrine level was decreased in this group (F = 4,35, p = 0.043). The triglyceride increase was significantly associated with epinephrine decrease (B = 0.087, p = 0.041), suggesting that Korean Red Ginseng may stabilize the sympathetic nervous system. In addition, we detected a significant group by time effect in the visually controlled continuous performance test, suggesting positive effects of Korean Red Ginseng on cognition. Conclusion: Korean Red Ginseng might help to stabilize the sympathetic nervous system and improve cognition in individuals with high stress.

• Journal of Veterinary Science
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• v.21 no.1
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• pp.5.1-5.12
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• 2020

The major glycoproteins of bovine gammaherpesvirus 4 (BoHV-4) are gB, gH, gM, gL, and gp180 with gB, gH, and gp180 being the most glycosylated. These glycoproteins participate in cell binding while some act as neutralization targets. Glycosylation of these envelope proteins may be involved in virion protection against neutralization by antibodies. In infected cattle, BoHV-4 induces an immune response characterized by low neutralizing antibody levels or an absence of such antibodies. Therefore, virus seroneutralization in vitro cannot always be easily demonstrated. The aim of this study was to evaluate the neutralizing capacity of 2 Argentine BoHV-4 strains and to associate those findings with the gene expression profiles of the major envelope glycoproteins. Expression of genes coding for the envelope glycoproteins occurred earlier in cells infected with isolate 10/154 than in cells infected with strain 07/435, demonstrating a distinct difference between the strains. Differences in serological response can be attributed to differences in the expression of antigenic proteins or to post-translational modifications that mask neutralizing epitopes. Strain 07/435 induced significantly high titers of neutralizing antibodies in several animal species in addition to bovines. The most relevant serological differences were observed in adult animals. This is the first comprehensive analysis of the expression kinetics of genes coding for BoHV-4 glycoproteins in 2 Argentine strains (genotypes 1 and 2). The results further elucidate the BoHV-4 life cycle and may also help determine the genetic variability of the strains circulating in Argentina.