• Journal of Korean Society of Coastal and Ocean Engineers
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• v.22 no.6
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• pp.353-360
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• 2010

The Kyunggi Bay in mid-west of Korea is a relatively large estuarine system that connects the Han River system with Yellow Sea. Due to macro-tidal range of more than 8 m, the urban estuary shows deep tidal channels and wide tidal flats. Since last 30 years, the coastal development is undergoing, yielding noticeable change in environment. Particularly the tidal flat dynamics are generally accepted as being related with tidal residual flows in this area (Kim et al., 2009). We have estimated the annual variation and vertical structure of residual currents with one-year long observed flows in two major tidal channels of Kyunggi Bay. The moving average method and tidal current harmonic analysis yield nearly the same results on residual flow. The residual flow in Jangbong channel ranges from 20 cm/s in summer to 30 cm/s in winter. It is noticeable that the residual flow in Jangbong channel is flood dominant throughout the year, while the flow in Seokmo channel is ebb-dominant residual flow with current speed range of 20-40 cm/s. Due to the baroclinic response of relatively shallow estuary, significant reduction of energy in bottom layers have been observed, indicating the importance of residual circulation to the tidal flat behavior.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.31 no.2
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• pp.242-248
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• 1986

To study the effect of cold water irrigation at the reproductive growth stage of rice plants on several growth characters related to source and sink and nutrient uptake, the present experiment was carried out under the different conditions of water temperature and water depth. Deep irrigation with normal temperature water increased culm length, panicle length and panicle exsertion but with cold water resulted adversely. Most sensi-tive response in 5 cm water-depth appeared at reduction division stage and in 20 cm depth at panicle formation stage. Secondary branches and spikelets were increased in number by deep irrigation with normal temperature water, but decreased and degenerated by deep irrigation with cold water at panicle formation stage resulting in high spikelet sterility and low grain filling. Deep irrigation with normal temperature water increased the contents of total nitrogen, phosphate, potassium and silicate in leaf blades, branches and chaff. However, cold water irrigation reduced the uptake of phosphate, potassium and silicate except nitrogen particularly in deep irrigation. Ratios of phosphate, potassium and silicate to total nitrogen content were decreased by cold water irrigation. Branches seemed to have higher requirements for phosphate, potassium and silicate than leaf blades and chaff. Silicate-to-total nitrogen ratio in leaf blades, branches and chaff had significant correlations with yield showing closer relationship between yield and the ratio of silicate to total nitrogen in branches in particu-lar.

• Development and Reproduction
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• v.21 no.4
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• pp.407-415
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• 2017

In the present study, we investigated the role of binding immunoglobulin protein/glucose-regulated protein, 78-kDa (BIP/GRP78)-regulated endoplasmic reticulum (ER)-stress on meiotic maturation and cumulus cells expansion in porcine cumulus-oocyte complexes (COCs). Previously, it has been demonstrated that unfolded protein response (UPR)-related genes, such as molecules involved in ER-stress defense mechanisms, were expressed in matured oocytes and cumulus cells during in vitro maturation (IVM) of porcine oocytes. However, BIP/GRP78-mediated regulation of ER stress in porcine oocytes has not been reported. Firstly, we observed the effects of knockdown of BIP/GRP78 (an UPR initiation marker) using porcine-specific siRNAs (#909, #693, and #1570) on oocyte maturation. Among all siRNAs, siRNA #693 significantly reduced the protein levels of UPR marker proteins (BIP/GRP78, ATF4, and P90ATF6) in porcine COCs observed by Western blotting and immunofluorescence analysis. We also observed that the reduction of BIP/GRP78 levels by siRNA#693 significantly inhibited the meiotic maturation of oocytes (siRNA #693: $32.5{\pm}10.1%$ vs control: $77.8{\pm}5.3%$). In addition, we also checked the effect of ER-stress inhibitors, tauroursodeoxycholic acid (TUDCA, $200{\mu}M$) and melatonin ($0.1{\mu}M$), in BIP/GRP78-knockdown oocytes. TUDCA and melatonin treatment could restore the expression levels of ER-stress marker proteins (BIP/GRP78, $p-eIF2{\alpha}$, $eIF2{\alpha}$, ATF4, and P90ATF6) in siRNA #693-transfected matured COCs. In conclusion, these results demonstrated that BIP/GRP78-mediated regulation of UPR signaling and ER stress plays an important role in in vitro maturation of porcine oocytes.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.3
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• pp.259-270
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• 2001

The present study was attempted to investigate the characteristics of epibatidine on secretion of catecholamines (CA) from the isolated perfused model of the rat adrenal gland, and to establish the mechanism of action. Epibatidine $(3{\times}10^{-8}\;M)$ injected into an adrenal vein produced a great inhibition in secretory response of CA from the perfused rat adrenal gland. However, upon the repeated injection of epibatidine $(3{\times}10^{-8}\;M)$ at 15 min-intervals, CA secretion was rapidly decreased after second injection of epibatidine. However, there was no statistical difference between CA secretory responses of both 1st and 2nd periods by the successive administration of epibatidine at 120 min-intervals. Tachyphylaxis to releasing effects of CA evoked by epibatidine was observed by the repeated administration. Therefore, in all subsequent experiments, epibatidine was not administered successively more than twice only 120 min-intervals. The epibatidine-induced CA secretion was markedly inhibited by the pretreatment with atropine, chlorisondamine, pirenzepine, nicardipine, TMB-8, and perfusion of $Ca^{2+}-free$ Krebs solution containing EGTA, while was not affected by diphenhydramine. Moreover, the CA secretion evoked by ACh for 1st period $(0{\sim}4\;min)$ was greatly potentiated by the simultaneous perfusion of epibatidine $(1.5{\times}10^{-8}\;M),$ but followed by time-dependently gradual reduction after 2nd period. The CA release evoked by high potassium $(5.6{\times}10^{-8}\;M),$ for 1st period $(0{\sim}4\;min)$ was also enhanced by the simultaneous perfusion of epibatidine, but those after 2nd period were not affected. Taken together, these experimental data suggest that epibatidine causes catecholamine secretion in a calcium dependent fashion from the perfused rat adrenal gland through activation of neuronal cholinergic (nicotinic and muscarinic) receptors located in adrenomedullary chromaffin cells. It also seems that epibatidine-evoked catecholamine release is not relevant to stimulation of histaminergic receptors.

• Journal of the Society of Disaster Information
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• v.14 no.3
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• pp.288-295
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• 2018

Purpose: The paper aims to compare the effectiveness of the two types of transport demand management measures, namely pull measures and push measures. Method: Case studies of two metropolitan areas in the developing world assess the extent to which increases in fuel prices can contribute to reducing automobile use and increasing the public transport use and the potential of urban rail transit to cause mode shift from automobiles. Within the case studies, a stated response survey of current car users has been conducted for Cairo and an on-line survey of rail transit users in Algiers. Results: There was a major proportion of car drivers who intend to switch to public transport, depending on the range of fuel prices in Cairo and a considerable proportion of rail users who have switched from automobiles resulting in a measurable reduction in CO2 emissions in Algiers. Conclusion: Investments in urban rail can be highly effective where there are demands for better public transport, but this type of pull measures can be much more effective if combined with push measures which significantly raise driving costs.

• Korean Journal of Agricultural and Forest Meteorology
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• v.11 no.4
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• pp.143-150
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• 2009

Deicing salt is used to melt snow and ice on the road for traffic safety during the winter season, which accumulates in the roadside vegetation and induces visible injuries. The damage may accelerate particularly when it coincides with early spring leaf out. In order to better understand the response mechanisms, C. kousa (3-year-old) was irrigated twice prior to leaf bud in a rhizosphere with solutions of 0.5, 1.0, and 3.0% calcium chloride ($CaCl_2$) concentration, that were made by using an industrial $CaCl_2$ reagent practical deicing material in Seoul. Physiological traits of the mature leaves were progressively reduced by $CaCl_2$ treatment, resulting in reductions of total chlorophyll contents, chlorophyll a:b, photosynthetic rate, quantum yield, stomatal conductance, $F_V/F_M$, and NPQ. On the contrary, light compensation point and dark respiration were increased at high $CaCl_2$ concentration. A decrease in intercellular $CO_2$ concentration by stomatal closure first resulted in a reduced photosynthetic rate and then was accompanied by low substance metabolic rates and photochemical damage. Based on the reduction of physiological activities at all treatments ($CaCl_2$ 0.5%, 1.0%, and 3.0%), C. kousa was determined as one of the sensitive species to $CaCl_2$.

• Restorative Dentistry and Endodontics
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• v.34 no.3
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• pp.192-198
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• 2009

This study was carried out in order to determine in vitro biocompatibility of white mineral trioxide aggregate (MTA), and to compare it with that of the commonly used materials, i. e. calcium hydroxide liner (Dycal), glass ionomer cement (GIC), and Portland cement which has a similar composition of MTA. To assess the biocompatibility of each material, cytotoxicity was examined using MG-63 cells. The degree of cytotoxicity was evaluated by scanning electron microscopy (SEM) and a colorimetric method, based on reduction of the tetrazolium salt 2,3 bis {2methoxy 4nitro 5[(sulfenylamino) carbonyl] 2H tetrazolium hydroxide} (XTT) assay. The results of SEM revealed the cells in contact with GIC, MTA. and Portland cement at 1 and 3 days were apparently healthy. In contrast, cells in the presence of Dycal appeared rounded and detached. In XTT assay, the cellular activities of the cells incubated with all the test materials except Dycal were similar, which corresponded with the SEM observation. The present study supports the view that MTA is a very biocompatible root perforation repair material. It also suggests that cellular response of Portland cement and GIC are very similar to that of MTA.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.10C
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• pp.995-1006
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• 2003

It is well know that in the wireless communication systems the transmitted signals can suffer from multipath fading due to the wave propagation characteristics and the obstacles over the paths, resulting in serious reduction in the power of the received signals. However, it is possible to take advantage of the inherent diversity imposed in the multipath reception if the underlying channel can be properly estimated. One of the diversity reception methods in this case is Rake processing. In this paper we study the Rake receivers for the direct-sequence spread-spectrum communication systems utilizing PN (pseudo noise) sequences to achieve spread spectrum. A conventional Rake receiver can use the finite-duration impulse (FIR) filter followed by the PN sequence demodulator, where the FIR filter coefficients are the reverse-ordered complex conjugate values of the fading channel impulse response estimates. Here, we propose a new Rake processing method by replacing the aforementioned PN code sequence with a new set of optimum demodulator coefficients. More specifically, the concept of the new optimum Rake processing is first introduced and then the optimum demodulator coefficients are theoretically derived. The performance obtained using the new optimum Rake processing is also calculated. The analytical results are verified by computer simulation. As a result, it is shown that the new optimum Rake processing method improves the MSE performance more than 10 dB over the conventional one using the fixed PN sequence demodulator. It is also shown that the new optimum Rake processing method improves the MSE performance about 10 dB over the Adaptive Correlator that performs the combining of the multipath components and PN demodulation concurrently. And finally, the MSE performance of the optimum Rake demodulator is very close to the MSE performance of OPSK demodulator under the AWGN channel.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.1
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• pp.31-38
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• 2009

Purpose: This study was to evaluate corneal topography, contrast sensitivity and ocular response of a RGP, back surface aspherical contact lens compared with a spherical contact lens. Methods: A total 37 subjects were fitted with a spherical lens in right eye and an aspherical in the left eye and were evaluated for changes in corneal topography and contrast sensitivity over a 2-month period. Results: Thirty-four of 37 subjects completed the 2-month study. The corneal topography did not show differences between spherical and aspherical RGP lenses. The eyes fitted with the aspherical lenses demonstrated a greater reduction in contrast sensitivity compared with their spherical counterparts under photopic condition. Subjects preferred comfort and ocular responses provided by the spherical lens. Conclusions: Corneal topography when comparing spherical and back surface aspherical RGP lenses did not show any significant difference in the subjects. Spherical RGP lens yields better contrast sensitivity and preference than aspherical RGP lens at photopic condition. Further investigation of aberrations induced by contact lens design is warranted to explain the observed differences in visual performance.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.2
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• pp.195-201
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• 2011

Nardostachys chinensis;Anti-proliferation;Cell cycle arrest;Differentiation;U937 cells; This study was conducted to determine the analgesic effect of Sokyungwhalhyul-tang(SKWHT) using the model of peripheral neuropathic pain model. A model of neuropathic pain was made by ligating left 5th lumbar spinal nerve of rats. After 1 days, the extract of SKWHT was orally administered daily. Rats were divided into four groups; (1) Control group(n=6), (2) Experimental group I(SKWHT-OA1, 100 mg/kg, n=6), (3) Experimental group II(SKWHT-OA2, 300 mg/kg, n=6), (4) Experimental group III(SKWHT-OA3, 500 mg/kg, n=6). After that, we examined the withdrawl response of neuropathic rats legs by von Frey filament and Hot plate at pre, $1^{th}$, $4^{th}$, $7^{th}$, $14^{th}$, $21^{th}$ days after the induction of neuropathic pain. And also we examined c-fos, GOT, GPT and histological study of Liver at 21th days. von Frey filament and Hot plate were increase in experimental group I, II, III than Con. especially group III was most significantly analgesic effect than the other groups at $14^{th}$, $21^{th}$ days. In c-fos protein expression on spinal cord, group III was most significantly reduction immunoreactivity at $21^{th}$ days and in blood serum GOT & GPT levels and histologic finding of Liver in all experimental groups were no significant difference with Con at $21^{th}$ days. According to the above results, SKWHT(500 mg/kg) may have a significant analgesic effect on the neuropathic pain.