• Women's Health Nursing
• /
• v.16 no.2
• /
• pp.116-125
• /
• 2010

Purpose: The purpose of this study was to investigate the relationship between health locus of control, exercise self-efficacy and exercise benefits / barriers of female college students. Methods: Convenient sampling was used to recruit participants from a University based in Pusan. Data were collected from October 15 to December 20, 2007, and participants were 322 students. The questionnaires administered consisted of Multidimensional Health Locus of Control (HLOC) Scales, Exercise Self-efficacy Scale, and Exercise Benefits / Barriers Scale. Descriptive statistics, ANOVA, and Pearson's correlation coefficients were used to analyze the data. Results: The mean scores for the HLOC among female students was HLOC-I: 22.24, HLOC-P: 16.82, HLOC-C: 15.16. The mean scores were exercise self-efficacy: 37.45, exercise benefit: 2.96, and exercise barriers: 2.89. The 'double external' response pattern of HLOC was the largest group in female students with significant difference in exercise benefit between response patterns of HLOC. There were significant correlations between HLOC-I, exercise self-efficacy, and exercise benefit/barriers. Conclusion: The results of this study suggest that tailored health management program by pattern of HLOC should be developed to promote the exercise behavior and enhance the exercise self-efficacy and benefit for female students.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.23
• /
• pp.10241-10244
• /
• 2015

Objective: To investigate the efficacy and side effects of Bifidobacterium tetragenous viable bacteria tablets in treating cancer patients with functional constipation during chemotherapy. Methods: A consecutive cohort of 100 cancer patients with functional constipation were divided into two equal groups: patients in the experimental group were given Bifidobacterium tetragenous viable bacteria tablets combined with chemotherapy, while patients in the control group received chemotherapy alone. After 4 weeks, the efficacy and side effects in treating functional constipation were evaluated. Results: Constipation in 48 patients in experimental group was controlled (9 returned to normal), with a total response rate of 96%, and 1 patient reported diarrhea (2%). In contrast only 16 patients in the control group demonstrated improvement and 34 were still constipated after chemotherapy, with a response rate of 32%. The difference in response rate was statistically significant (P<0.05). Conclusion: This study suggested that Bifidobacterium tetragenous viable bacteria tablets are effective and safe in treating cancer patients with functional constipation during chemotherapy.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.12
• /
• pp.4993-4996
• /
• 2015

Background: To evaluate the efficacy and safety of albumin-bound paclitaxel-based chemotherapy in treatment for patients with advanced esophageal cancer who failed in first-line chemotherapy. Materials and Methods: We collected29 advanced esophageal cancer patients who received albumin-bound paclitaxel-based chemotherapy fromJune 2009 to September 2013, and the efficacy and safety of the compound were evaluated. These patients were treated with $100-150mg/m^2$ nab-paclitaxel on days 1,8. The cycle was repeated every 3 weeks. Clinical efficacy was evaluated every two cycles. Results: Of the 29 patients, two persons interrupted treatment because of adverse reactions, failed to evaluate efficacy effect. The rest of 27 patients who could be evaluated for short-term response, 10 patients (37%) achieved partial response, 2 (7.4%) remained stable disease, and 15 (55.6%) had progressivedisease. The objective response rate was 37%, and the disease control rate was 44.4%.The median time to progression was 6.6 months.The major adverse reactions includedalopecia (62.07%), neutropenia (65.5%), gastrointestinalreaction (10.3%) andsensory neuropathy(6.8%). Conclusions: The albumin-bound paclitaxel-based chemotherapy is efficacy and safety in treatment for patients with advanced esophageal cancer who failed in first-line chemotherapy.

• Korean Journal of Child Studies
• /
• v.29 no.3
• /
• pp.239-252
• /
• 2008

This study was to explore the causal relationship among teacher efficacy, teachers' approaches to instruction, and students' achievement goal orientation. Among the 278 6th grade students (average age: 12 years) who completed a self-report questionnaire during the second term, 230 (102 boys, 128 girls) returned the completed questionnaire (overall response rate : 82.7%). Measures of teacher efficacy, teachers' approaches to instruction, and students' achievement goal orientation were based on students' perceptions. Structural equation modeling tested relationships among the variables. Findings were that teacher efficacy influenced both students' achievement goal orientation and teachers' approaches to instruction. Teacher efficacy positively influenced teachers' mastery approach to instruction and students' mastery and performance approach goal orientations, whereas teacher efficacy negatively influenced teachers' performance approach to instruction.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.19
• /
• pp.8405-8408
• /
• 2014

Background: This analysis was conducted to evaluate the efficacy and safety of temozolomide based chemotherapy in treating patients with glioma. Methods: Clinical studies evaluating the efficacy and safety of temozolomide based regimens for patients with glioma were identified using a predefined search strategy. Pooled response rates (RRs) were calculated. Results: In temozolomide based regimens, 5 clinical studies including 152 patients with advanced glioma were considered eligible for inclusion. Four clinical studies included temozolomide. Systematic analysis suggested that, in all patients, pooled CR was 21% (32/152), and PR was 21% (32/152). Grade 3/4 toxicity included neutropenia, thrombocytopenia, and anemia. No grade 3 or 4 renal or liver toxicity was observed. No treatment related death occurred with temozolomide based treatment. Conclusion: This systematic analysis suggests that temozolomide based regimens are associated with mild response rate and acceptable toxicity for treatment of glioma patients.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 2007.11a
• /
• pp.11-15
• /
• 2007

Metabolomics is an emerging technology which makes it possible to evaluate change of biological system in response to the physiological, environmental alterations. It has advantages in the simplicity and sensitivity to analyze metabolites since the researcher can use cutting edge instrument, such as mass spectrometry and simple sample preparation method compared to genomics or proteomics. Nowadays this technology has been tried in pharmaceutical area to investigate toxicity and efficacy of drug candidates and drugs in preclinical test. The metabolomic applications on the pharmaceutics for early prediction on toxicity and efficacy are described in this presentation. The multivariate analysis to get metabolic fingerprinting and its relations with the physiological changes are investigated with several drugs. Feasibility of metabolomic application for pharmaceutical area would be suggested from those researches.

• Nutrition Research and Practice
• /
• v.4 no.1
• /
• pp.75-81
• /
• 2010

This study explored the conceptual framework of dieticians' intentions to recommend functional food and the mediating role of consumption frequency. A web-based survey was designed using a self-administered questionnaire. A sample of Korean dieticians (N=233) responded to the questionnaire that included response efficacy, risk perception, consumption frequency, and recommendation intention for functional foods. A structural equation model was constructed to analyze the data. We found that response efficacy was positively related to frequency of consumption of functional foods and to recommendation intention. Consumption frequency also positively influenced recommendation intention. Risk perception had no direct influence on recommendation intention; however, the relationship was mediated completely by consumption frequency. Dieticians' consumption frequency and response efficacy were the crucial factors in recommending functional foods. Dieticians may perceive risks arising from the use of functional foods in general, but the perceived risks do not affect ratings describing dieticians' intentions to recommend them. The results also indicated that when dieticians more frequently consume functional foods, the expression of an intention to recommend functional foods may be controlled by the salience of past behaviors rather than by attitudes.

• Fashion & Textile Research Journal
• /
• v.6 no.5
• /
• pp.595-604
• /
• 2004

This study is to investigate complaining behavior of consumers who purchase fashion products on the internet, as well as to find how the complaining behaviors are related to the consumers' characteristics. The subjects of this study are limited to the consumers who have experienced dissatisfaction when purchasing fashion products through the internet. The questionnaires were administered to male and female respondents using the internet shopping mall. The results can be summarized as follows: The factor analysis shows that consumer complaining behaviors are fitted well into four factors(direct complaining behavior, private complaining behavior, third-party complaining behavior, and no response). In the difference analysis by consumer's complaining behavior styles and gender, private complaining and third-party complaining behavior were significant statistically. In the difference analysis between consumer's complaining behavior styles and internet self-efficacy. Internet self-efficacy was significantly different according to consumer's complaining behavior styles, especially for direct complaining, third-party complaining and no response. Private complaining behavior, third-party complaining behavior and no response were negatively related to consumer retention, while direct complaining behavior was not.

• Journal of Korean society of Dental Hygiene
• /
• v.17 no.6
• /
• pp.1003-1012
• /
• 2017

Objectives: The purpose of this study is to investigate the knowledge and self-efficacy of dental hygiene students after cardiopulmonary resuscitation (CPR) education. Methods: A self-reported questionnaire was filled out by 260 dental hygiene students in the period between 5 November 2015 and 30 December 2015. The data analysis was performed by SPSS win 22.0 program for frequency analysis, chi-square analysis, and dichotomies multiple response analysis. Results: Self-efficacy and knowledge increased after CPR education. Most of the dental hygiene students are statistically significant difference in self-efficacy depending on CPR knowledge. Conclusions: Based on the results of this study, we suggest that the theory and practice of CPR, if taught to dental hygiene students, will boost their self-efficacy, and enable them to perform it correctly when faced with and emergency situation.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.20 no.4
• /
• pp.482-490
• /
• 2014

Purpose: This research compares self-leadership, team efficacy, problem solving processes and task satisfaction in response to teaching methods applied to nursing students, and determines whether variations exist. Method: This research experiments before and after the training of a nonequivalent group. The subjects were 36 learners of action learning methods and 39 learners of nursing course methods, and the research took place from October through December 2012. Results: Prior to the training, the general features and measurable variables of the two groups of subjects were similar, and self-leadership, team efficacy, problem solving process and task satisfaction in both groups were elevated compared to pre-training. In particular, in comparison with the nursing course, there was a notable difference in scores, the action learning method receiving high scores in the problem solving process (t=2.92, p=.005) and task satisfaction (t=2.54, p=.013) Conclusion: It is recommended that educators not only conduct the practice training course for teaching methods, but also incorporate action learning.