• Journal of Yeungnam Medical Science
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• v.18 no.2
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• pp.277-286
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• 2001

Background: This study was undertaken to evaluate the diagnostic sensitivity of several muscles in repetitive nerve stimulation test (RNST) for myasthenia gravis (MG) patients. Materials and Methods: The study population consisted of 39 MG patients classified by modified Ossermann's classification. Using Stalberg's method, RNST was systematically performed in facial (orbicularis oculi and nasalis) and upper extremity (flexor carpi ulnaris, abductor digiti quinti and anconeus) muscles. Results: The significant electrodecremental response of RNST were noted in orbicularis oculi(58.9%), nasalis (51.3%), flexor carpi ulnaris(42%), anconeus(41%) and abductor digiti quinti muscles(27%). Among the 3 muscles of upper extremity(abductor digiti quinti, flexor carpi ulnaris and anconeus), the positive electrodecremental response of anconeus muscles was significantly higher than other two muscles(p<0.05) in type IIa, IIb and there were no statistical differences of the positive electrodecremental response between orbicularis oculi and nasalis muscles. The facial muscles showed more prominent decremental responses than upper extremity muscles in type I MG(p<0.05). In type IIa MG patients, there were no significant statistical differences between facial and upper extremity muscles but significant statistical differences among upper extremity muscles. In type IIb MG patients, there were no significant statistical differences in all tested muscles in spite of the increased positive electrodecremental response of RNST. Conclusion: On the basis of this study, RNST would be initially performed for the orbicularis or nasalis in type I MG and for the anconeus in type IIa or IIb MG.

• Journal of Korean Academy of Nursing
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• v.4 no.3
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• pp.1-12
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• 1974

It is the purpose of this study to determine an effective method of communication between teachers and students. This study was done by using the theory, methods and tools of transactional analysis as developed by Borne and Harris. In order to achieve this objective: First; The teacher and student communication process is to be used, noting the student's reaction when the teacher uses "Adult" and "Parent" stimulus. Second; The effectiveness of the reaction toward the "Adult" and "Parent" stimulus is to be determined with these objectives in mind. The problems of this research study are as follows; What influence on the response of the student is brought about by the method of communication used by the teacher? 1) When the teacher uses the "Parent" Stimulus method what response of the student is shown? 2) When the teacher uses the "Adult" Stimulus method what response of the student is shown? 3) What method of communication helps to promote the student′s growth? In order to determine the answers to these questions data was collected from 40 first year students at a school of nursing in Inchon. These students were divided into two groups and the unstandardized interview technique was used to interview each student for ten minutes. A tape recording was made of each interview and the nonverbal communication was recorded by process recording immediately following each interview. The recorded material obtained from the two groups was analysed and then the Borne and Harris transactional analysis method was used in analysing the writer of this thesis undertook. Hypothesis 1. When the teacher used the "Parent" stimulus the student′s response was more frequently "Child" than "Adult", the results showed a significant difference of P〈0.001. Hypothesis 2. When the teacher used the "Adult" Stimulus the student′s response was more frequently of "Adult" than "Child", the results showed a significant difference of P〈0.001, The following conclusions are drawn from this study: 1) There is an indication that the teachers use of "Parent" stimulus communication is not an effective method to increase the growth of the student. 3) Since the teachers use of "Adult" stimulus resulted in an increase in the "Adult" response of the student there is ah indication that use of an effective communication method can help the student to develop. The writer of this research paper suggests for further study the following; 1) A comparison of the differences in response to the giving of both "Adult" and "Parent" stimulus to the same Students. 2) A comparison of the differences in student response to the communication method according to the student′s grade, age, sex and level in school.

• Structural Engineering and Mechanics
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• v.53 no.5
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• pp.897-919
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• 2015

In this study, the effects of ground shocks due to explosive loads on the dynamic response of historical masonry bridges are investigated by using the multi-point shock response spectrum method. With this purpose, different charge weights and distances from the charge center are considered for the analyses of a masonry bridge and depending on these parameters frequency-varying shock spectra are determined and applied to each support of the two-span masonry bridge. The net blast induced ground motion consists of air-induced and direct-induced ground motions. Acceleration time histories of blast induced ground motions are obtained depending on a deterministic shape function and a stationary process. Shock response spectrums determined from the ground shock time histories are simulated using BlastGM software. The results obtained from uniform and multi-point response spectrum analyses cases show that significant differences take place between the uniform and multi-point blast-induced ground motions.

• Structural Engineering and Mechanics
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• v.68 no.2
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• pp.159-170
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• 2018

This paper aims to develop response modification factors for stiffness degrading structures by incorporating soil-structure interaction effects. A comprehensive parametric study is conducted to investigate the effects of key SSI parameters, natural period of vibration, ductility demand and hysteretic behavior on the response modification factor of soil-structure systems. The nonlinear dynamic response of 6300 soil-structure systems are studied under two ensembles of accelograms including 20 recorded and 7 synthetic ground motions. It is concluded that neglecting the stiffness degradation of structures can results in up to 22% underestimation of inelastic strength demands in soil-structure systems, leading to an unexpected high level of ductility demand in the structures located on soft soil. Nonlinear regression analyses are then performed to derive a simplified expression for estimating ductility-dependent response modification factors for stiffness degrading soil-structure systems. The adequacy of the proposed expression is investigated through sensitivity analyses on nonlinear soil-structure systems under seven synthetic spectrum compatible earthquake ground motions. A good agreement is observed between the results of the predicted and the target ductility demands, demonstrating the adequacy of the expression proposed in this study to estimate the inelastic demands of SSI systems with stiffness degrading structures. It is observed that the maximum differences between the target and average target ductility demands was 15%, which is considered acceptable for practical design purposes.

• Nuclear Engineering and Technology
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• v.20 no.2
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• pp.71-79
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• 1988

Published data of the efficiency of CR-39 detectors as a function of neutron energy from different laboratories show wide variations in the response obtained. These variations result from differences in etching conditions, in the materials and thickness of the radiator, in the sensitivities of CR-39 from different manufacturers and perhaps in criteria used for the size of spots that are counted. This paper describes some effects of these factors on the energy and angular response with calculational results. Calculated and measured results of the variations of response with neutron incident angie are more consistent than those of energy response. The data calculated show that the angular response is not a strong function of neutron energy except below about 0.3 MeV.

• The Korean Journal of Ecology
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• v.28 no.2
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• pp.105-112
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• 2005

Environmental factors such as light and low $CO_2$ concentrations trigger events which may result in stomatal opening. Stomatal aperature is largely controlled by the solute contents of guard cells, but not exclusively, by through changes in their content of potassium salts, with $K^+$ balanced either by $Cl^-$ or malate, depending on the species and conditions. However, how these signals are sensed and how they are transduced into driving the ion fluxes that control stomatal movements is not still fully understood. The basic role of stomata is regulating transpiration and photosynthesis. Photosynthesis plays a central role in the physiology of plants and an understanding of its response to light is, therefore, critical to any discussion of how plants sense and respond to light. It had been proposed that the evidences pointed three possible mechanisms for the light response. Firstly, there is a direct response of stomata to light. Secondly. there is an indirect response of stomata to light through the effect of $CO_2$. Lastly, there are some evidences for a third effect of light on stomata. However, attempts to investigate how these three possible mechanisms explained in detail in response to light have not been made. Therefore, this study is examined the differences among these three possible mechanisms.

• Journal of Animal Science and Technology
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• v.63 no.6
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• pp.1376-1385
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• 2021

Foot-and-mouth disease, one of the most contagious diseases in cloven-hoofed animals, causes significant economic losses. The pathogenesis of foot-and-mouth disease virus (FMDV) infection is known to differ with age of the animals. In this study, we aimed to reveal the difference in immunological response in the initial stage of FMDV infection between piglets and adult pigs. Peripheral blood mononuclear cells (PBMCs) were isolated from 3 piglets (8 weeks old) and 3 pigs (35 weeks old) that were not vaccinated against FMDV. O-type FMDV (2 × 10² median tissue culture infectious dose) was inoculated into porcine PBMCs and the cells were incubated at 37.0℃ under 5% CO₂ for various time periods (0, 1, 3, 6, 12, 24, and 48 h). The total RNA was obtained from the FMDV-inoculated PBMCs after each time point, and the virus titer was investigated in these RNA samples. Furthermore, dynamics of mRNA expression of the six tested cytokines (interferon [IFN]-α, IFN-γ, interleukin [IL]-6, IL-8, IL-10, and tumor necrosis factor [TNF]-α) in FMDV-inoculated porcine PBMCs were evaluated by time-series analysis to determine the differences, if any, based on the age of the pigs. The PBMCs of piglets contained the highest quantity of FMDV mRNA at 6 hours post-inoculation (hpi), and the PBMCs of pigs had the highest quantity of FMDV mRNA at 3 hpi. The mean cycle threshold-value in the PBMCs steadily decreased after the peak time point in the piglets and pigs (6 and 3 hpi, respectively). The dynamics of mRNA expression of all cytokines except TNF-α showed age-dependent differences in FMDV-inoculated PBMCs. The mRNA expression of most cytokines was more pronounced in the piglets than in the pigs, implying that the immune response against FMDV showed an age-dependent difference in pigs. In conclusion, within 48 hpi, the 8-week-old piglets responded more rapidly and were more sensitive to FMDV infection than the 35-week-old pigs, which could be associated with the difference in the pathogenesis of FMDV infection among the pigs. These results provide valuable insights into the mechanisms underlying the age-dependent differences in immune response in pigs against FMDV infection.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.71-83
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• 2021

Purpose : This study compared the differences in power and agility of athletes in each sports using visual response speed test (VRST) scores after conducting 10 weeks of body stability exercise (BSE) on elementary school athletes in handball, football, volleyball and conducted a post-hoc test on the measured values. The subjects of this study were baseball (n=27), taekwondo (n=22), and football (n=23) athletes with at least two years of athletic experience. A total of 72 elementary school athletes were measured by VRST after 10 weeks of BSE under the same conditions. Methods : For VRST measurement of the upper extremity, the right and left hands were alternately touched in the order the blazepod equipment lights were turned on. The number of touches for 15 seconds and response touch were measured. In the case of the measurement of lower extremity the left lower extremity was measured first when the Blaze pod equipment light came on. The average value was obtained by measuring 3 times using a measurement sensor with the position indicated in order to measure the upper arms and legs the same. Results : This study confirmed homogeneity among sports and that VRST improved after implementing BSE for sports. However, no statistically significant difference was identified when comparing VRST improvements between sports, and post-hoc test results showed no significant differences either. Conclusion : After applying the BSE program under the same conditions for 10 weeks to elementary school students who can improve their power and agility the most, the results of the examination using the Blaze pod showed that the power and agility of baseball, taekwondo, and soccer players were similarly improved. From the fact that there was no significant difference among sports, it could be inferred that the BES training program could improve VRST without being limited to some sports.

• Journal of the Earthquake Engineering Society of Korea
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• v.20 no.4
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• pp.257-268
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• 2016

In the companion papers (I, II), site-specific response analyses were performed at more than 300 domestic sites and a new site classification system and design response spectra (DRS) were proposed using the results of the site-specific response analyses. In this paper, the proposed site classification system and the design response spectra are compared with those in other seismic codes and verified by different methods. Firstly, the design response spectra are compared with the design response spectra in Eurocode 8, KBC 2016 and MOCT 1997 to estimate quantitative differences and general trends. Secondly, site-specific response analyses are carried out using $V_S$-profiles obtained using field seismic tests and the results are compared with the proposed DRS in order to reduce the uncertainty in using the SPT-N value in site-specific response analyses in the companion paper (I). In addition, site coefficients from real earthquake records measured in Korean peninsula are used to compare with the proposed site coefficients. Finally, dynamic centrifuge tests are also performed to simulate the representative Korean site conditions, such as shallow depth to bedrock and short-period amplification characteristics. The overall results showed that the proposed site classification system and design response spectra reasonably represented the site amplification characteristic of shallow bedrock condition in Korea.

• Clinical and Experimental Reproductive Medicine
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• v.38 no.3
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• pp.153-158
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• 2011

Objective: The aim of this study was to investigate whether anti-M$\ddot{u}$llerian hormone (AMH) levels could be predict ovarian poor/hyper response and IVF cycle outcome. Methods: Between May 2010 and January 2011, serum AMH levels were evaluated with retrospective analysis. Three hundred seventy infertile women undergoing 461 IVF cycles between the ages of 20 and 42 were studied. We defined the poor response as the number of oocytes retrieved was equal or less than 3, and the hyper response as more than 25 oocytes retrieved. Serum AMH was measured by commercial enzymelinked immunoassay. Results: The number of oocytes retrieved was more correlated with the serum AMH level (r=0.781, $p$ <0.01) than serum FSH (r=-0.412, $p$ <0.01). The cut-off value of serum AMH levels for poor response was 1.05 ng/mL (receiver operating characteristic [ROC] curves/area under the curve [AUC], $ROC_{AUC}$=0.85, sensitivity 74%, specificity 87%). Hyper response cut-off value was 3.55 ng/mL $ROC_{AUC}$=0.91, sensitivity 94%, specificity 81%). When the study group was divided according to the serum AMH levels (low: <1.05 ng/mL, middle: 1.05 ng/mL - 3.55 ng/mL, high: >3.55 ng/mL), the groups showed no statistical differences in mature oocyte rates (71.6% vs. 76.5% vs. 74.8%) or fertilization rates (76.9% vs. 76.6% vs. 73.8%), but showed significant differences in clinical pregnancy rates (21.7% vs. 24.1% vs. 40.8%, $p$=0.017). Conclusion: The serum AMH level can be used to predict the number of oocytes retrieved in patients, distinguishing poor and high responders.