• Title/Summary/Keyword: Response Curve

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Bending Fatigue Life Assessment of Aged CWR using the Field Test (현장측정을 통한 노후레일의 휨 피로수명 평가)

  • Park, Yong-Gul;Sung, Deok-Yong;Park, Hong-Kee;Kong, Sun-Yong
    • Journal of the Korean Society for Railway
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    • v.11 no.3
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    • pp.317-325
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    • 2008
  • As a result of recent research, it is reported that the periodic replacements criterion of rails is able to extend as grinding rail surface and using the continuous welded rail (CWR). This study evaluated correlation between conditions of track and load capacity of rail by analysing the dynamic response of track while the metro train is running. Also, it was converted the measured stress waveform into stress frequency histogram by the rain-flow counting methods, and then accumulated fatigue damage ratio and remaining service life of laid rail were calculated so as the apply the equivalence of stress to S-N curve of a new welded rail. Finally, this study suggests a revision of the periodic replacements criterion of CWR, which was based on accumulated passing tonnage, classified by the types and conditions of track system.

Stress-induced Decrease of Granule Cell Proliferation in Adult Rat Hippocampus: Assessment of Granule Cell Proliferation Using High Doses of Bromodeoxyuridine Before and After Restraint Stress

  • Kim, Sung-Jin;Lee, Kuem-Ju;Shin, You-Chan;Choi, Song-hyen;Do, Eunju;Kim, Sangduk;Chun, Boe-Gwun;Lee, Min-Soo;Shin, Kyung-Ho
    • Molecules and Cells
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    • v.19 no.1
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    • pp.74-80
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    • 2005
  • Stress is known to inhibit granule cell proliferation in the hippocampus. However, recent studies suggest that the commonly used dose of bromodeoxyuridine (BrdU) is insufficient to label all fractions of granule cells. Furthermore, stress-induced changes in BrdU availability may influence the labeling of newly born cells. To investigate whether changes in BrdU availability affect measurements of stress-induced granule cell proliferation, granule cell proliferation was assessed using injection of high doses of BrdU before and after restraint stress lasting 1 h. In addition, to determine whether stress-induced changes in plasma corticosterone levels were influenced by the BrdU, time-dependent changes in plasma corticosterone levels over 2 h after BrdU injection were compared with total accumulated plasma corticosterone levels [as determined by areas under the curve (AUC)]. Restraint stress significantly reduced the numbers of BrdU-labeled cells and clusters in the granule cell layer (GCL) of rats that received BrdU after stress, and decreases of similar magnitude were observed when the rats were given BrdU before stress. BrdU injection enhanced the stress-induced plasma corticosterone response, but there was no difference between the mean AUCs of plasma corticosterone levels of animals injected with BrdU before or after stress. These observations suggest that restraint stress decreases granule cell proliferation, and that this may be influenced by the extent and duration of plasma corticosterone increases rather than by changes in the availability of BrdU.

Effects of Sunghyangchungisan on contractile Reactivity of Isolated Rabbit Carotid Artery (성향정기산(星香正氣散)이 가토(家?)의 경동맥(頸動脈) 평활근(平滑筋) 긴장도(緊張度) 조절(調節)에 미치는 영향(影響))

  • Kim, Young-Kyun;Ko, Woo-Shin;Kim, Jong-Hoon
    • The Journal of Korean Medicine
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    • v.19 no.2
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    • pp.228-243
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    • 1998
  • This study was undertaken to evaluate the effect of Sunghyangchungisan (SHCS) on the regulation of vascular tone. Vascular rings isolated from rabbit carotid artery were myographed isometrically in isolated organ baths and the effect of SHCS on contractile activities were determined. SHCS relaxed the arterial rings which were pre-contracted by phenylephrine(PE). The responses to SHCS were partially dose-dependent at concentrations lower than 0.5 mg/ml. When SHCS was applied prior to the exposure to PE, it inhibited the PE-induced contraction by a similar magnitude which was comparable to the relaxation of pre-contracted arterial rings. Washout of SHCS after observing its relaxant effect resulted in a full recovery of PE-induced contractions, indicating that the action mechanism is reversible. The observation that SHCS did not change the $ED_{50}$ of PE on its dose-response curve ruled out the possible interaction of SHCS and ${\alpha}-receptor$. The relaxant effect of SHCS was not affected by removal of endothelium, and pretreatment of the arterial rings with methylene blue or nitro-L-arginine. This results suggest that the action of SHCS is not mediated by endothelium nor soluble guanylate cyclase. SHCS relaxed high $K^{+}-induced$ contractions as well, whereas it failed to relax phorbol ester-induced contractions. When contraction was induced by additive application of $Ca^{2+}$ in arterial rings which were pre-depolarized by high $K^+$ in a $Ca^{2+}-free$ solution, the relaxant effect of SHCS was attenuated by increasing the $Ca^{2+}$ concentration. SHCS, when applied to the arterial rings pre-contracted by PE and then relaxed by nifedipine, a $Ca^{2+}$ channel blocker, did not show additive relaxation. From above results, it is suggested that SHCS relax PE-induced contraction of rabbit carotid artery in an endothelium-independent manner, and inhibition of $Ca^{2+}$ influx may contribute to the underling mechanism.

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Effect of Poncirus Trifoliata on Colonic Motility in Spinal Cord Injured Rats (척수손상 흰쥐에서 대장 운동에 대한 지실의 효과)

  • Choi, Chul-Won;Joo, Min-Cheol;Lee, Moon-Young
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.4
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    • pp.13-24
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    • 2008
  • Objectives : The purpose of this study was to investigate the effect of Poncirus Trifoliata(PT) on improvement of fecal impaction in spinal cord injured(SCI) rats. Methods : Fifteen adult Sprague-Dawley female rats were used weighing 200~250 g. A complete spinal cord transection was performed surgically at the T10 cord level. Experimental groups were assigned into 3 groups: Control(n=5), SCI+vehicle(n=5) and SCI+PT(n=5). PT was administered 100mg/kg in 0.5ml every 24 hours from 1st operation day to 7th day. We measured the body weight and food intake as well as the number and the weight of fecal pellet every morning. After 1 week of operation, whole colon was divided into proximal and distal segments under anesthesia. Each segment of colon was mounted with longitudinal direction in a organ bath. We measured spontaneous contraction and compared the area under the curve in each segments. Enhanced responses were observed by acetylcholine($10^{-6}M$), 40 mM KCl solution, L-NAME($10^{-4}M$). Results : The fecal number and weights were significantly higher in the group of SCI+PT than SCI+vehicle group(p<0.05). In organ bath study, area under the curves of the spontaneous contraction in SCI+vehicle and SCI+PT groups were significantly increased compared to control group. Contractility of distal colon in response to acetylcholine or KCl in SCI+vehicle group was significantly decreased compared to other groups(p<0.05). Conclusions : These results suggest that PT might be useful to promote bowel emptying in spinal cord injured rats.

CO2 emission Reduction and Load factor improvement of Power Systems, using Geothermal Source Heat Pump (지열히트펌프 활용을 통한 전력계통 부하율 향상 및 CO2 감축)

  • Lee, Geon-Woo;Lee, Sang-Joong;Yang, Seong-Deog
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2008.10a
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    • pp.349-354
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    • 2008
  • August 2008, Our country was announced the Energy Vision 2030 for strengthening response capability climate change by the greenhouse effect, 'Stable supply of energy' and 'Efficient systems'. According to the report, Our country is the world's top 10 is a country that consumes a lot of energy. and more than 97% of the energy because it is dependent on foreign imports, The importance of NRE(New and Renewable Energy) is rising significantly, This paper was applied geothermal heat pump it one kind of the renewable energy equipment, in General buildings, and analyzed the effect of the installation. Thus, to improve the load factor of the Electric power system was proposed, and As a result, can be expected the energy cost savings and the reduction of greenhouse gases, through Economic electric power supply.

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Cyclic tests on RC joints retrofitted with pre-stressed steel strips and bonded steel plates

  • Yu, Yunlong;Yang, Yong;Xue, Yicong;Wang, Niannian;Liu, Yaping
    • Structural Engineering and Mechanics
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    • v.75 no.6
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    • pp.675-684
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    • 2020
  • An innovative retrofit method using pre-stressed steel strips and externally-bonded steel plates was presented in this paper. With the aim of exploring the seismic performance of the retrofitted RC interior joints, four 1/2-scale retrofitted joint specimens together with one control specimen were designed and subjected to constant axial compression and cyclic loading, with the main test parameters being the volume of steel strips and the existence of externally-bonded steel plates. The damage mechanism, force-displacement hysteretic response, force-displacement envelop curve, energy dissipation and displacement ductility ratio were analyzed to investigate the cyclic behavior of the retrofitted joints. The test results indicated that all the test specimens suffered a typical shear failure at the joint core, and the application of externally-bonded steel plates and that of pre-stressed steel strips could effectively increase the lateral capacity and deformability of the deficient RC interior joints, respectively. The best cyclic behavior could be found in the deficient RC interior joint retrofitted using both externally-bonded steel plates and pre-stressed steel strips due to the increased lateral capacity, displacement ductility and energy dissipation. Finally, based on the test results and the softened strut and tie model, a theoretical model for determining the shear capacity of the retrofitted specimens was proposed and validated.

Modeling of a linear GMR Isolator Utilizing Spin Valves (스핀밸브를 이용한 선형 GMR 아이솔레이터의 모델링)

  • Park, S.;Jo, S.
    • Journal of the Korean Magnetics Society
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    • v.14 no.6
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    • pp.232-235
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    • 2004
  • Linear GMR isolator which is profitable for transmitting analog signal was modeled and the output voltage and current in relation to the input current were investigated. GMR isolator modeling was divided into two parts, namely magnetic and electric parts. The flow chart of the modeling was drawn in which the MR curve of the spin valves were incorporated to obtain the electrical voltage output. For magnetic modeling, 3-dimensional model of planar coil was analyzed by FEM method to obtain the magnetic field strength corresponding to the input current. Coil efficiency of the planar coil having magnetic core layer was shown to have about 1.5 times larger than that of the coil without the magnetic core layer. The feedback coil current(output current) corresponding to the input coil current was calculated to be within ${\pm}$0.25 mA of the linear fitting function of I$\_$out/= I$\_$in/-5 mA. Also, the response time and output waveforms were obtained when the coil current was a rectangular waveform. The rise time and fall time was 6 ${\mu}\textrm{s}$, respectively when the slew rate of the op-amp was 0.3 V/${\mu}\textrm{s}$.

Health monitoring of a new hysteretic damper subjected to earthquakes on a shaking table

  • Romo, L.;Benavent-Climent, A.;Morillas, L.;Escolano, D.;Gallego, A.
    • Earthquakes and Structures
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    • v.8 no.3
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    • pp.485-509
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    • 2015
  • This paper presents the experimental results obtained by applying frequency-domain structural health monitoring techniques to assess the damage suffered on a special type of damper called Web Plastifying Damper (WPD). The WPD is a hysteretic type energy dissipator recently developed for the passive control of structures subjected to earthquakes. It consists of several I-section steel segments connected in parallel. The energy is dissipated through plastic deformations of the web of the I-sections, which constitute the dissipative parts of the damper. WPDs were subjected to successive histories of dynamically-imposed cyclic deformations of increasing magnitude with the shaking table of the University of Granada. To assess the damage to the web of the I-section steel segments after each history of loading, a new damage index called Area Index of Damage (AID) was obtained from simple vibration tests. The vibration signals were acquired by means of piezoelectric sensors attached on the I-sections, and non-parametric statistical methods were applied to calculate AID in terms of changes in frequency response functions. The damage index AID was correlated with another energy-based damage index -ID- which past research has proven to accurately characterize the level of mechanical damage. The ID is rooted in the decomposition of the load-displacement curve experienced by the damper into the so-called skeleton and Bauschinger parts. ID predicts the level of damage and the proximity to failure of the damper accurately, but it requires costly instrumentation. The experiments reported in this paper demonstrate a good correlation between AID and ID in a realistic seismic loading scenario consisting of dynamically applied arbitrary cyclic loads. Based on this correlation, it is possible to estimate ID indirectly from the AID, which calls for much simpler and less expensive instrumentation.

Experimental and analytical investigation on seismic behavior of RC framed structure by pushover method

  • Sharma, Akanshu;Reddy, G.R.;Eligehausen, R.;Vaze, K.K.
    • Structural Engineering and Mechanics
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    • v.39 no.1
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    • pp.125-145
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    • 2011
  • Pushover analysis has gained significant popularity as an analytical tool for realistic determination of the inelastic behaviour of RC structures. Though significant work has been done to evaluate the demands realistically, the evaluation of capacity and realistic failure modes has taken a back seat. In order to throw light on the inelastic behaviour and capacity evaluation for the RC framed structures, a 3D Reinforced concrete frame structure was tested under monotonically increasing lateral pushover loads, in a parabolic pattern, till failure. The structure consisted of three storeys and had 2 bays along the two orthogonal directions. The structure was gradually pushed in small increments of load and the corresponding displacements were monitored continuously, leading to a pushover curve for the structure as a result of the test along with other relevant information such as strains on reinforcement bars at critical locations, failure modes etc. The major failure modes were observed as flexural failure of beams and columns, torsional failure of transverse beams and joint shear failure. The analysis of the structure was by considering all these failure modes. In order to have a comparison, the analysis was performed as three different cases. In one case, only the flexural hinges were modelled for critical locations in beams and columns; in second the torsional hinges for transverse beams were included in the analysis and in the third case, joint shear hinges were also included in the analysis. It is shown that modelling and capturing all the failure modes is practically possible and such an analysis can provide the realistic insight into the behaviour of the structure.

A Comparison of Photosynthetic Characteristics of Three Ligularia species Under-tree Cultivation (임간재배지에서 세 종 곰취(Ligularia)속 식물의 광합성특성 비교)

  • Kim, Gab-Tae
    • Korean Journal of Plant Resources
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    • v.21 no.5
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    • pp.357-361
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    • 2008
  • The photosynthetic characteristics of three Ligularia species, L. fischeri, L. fischeri var. spiciformis and L. stenocephala under-tree cultivated in Dunnae-myeon, Hoengsung-gun were measured and compared. Total mean photosynthetic rate increased with increasing the light intensity up to 2,000 PPFD. Mean photosynthetic rate of L. fischeri increased to maximum value of $21.1{\mu}mol\;CO_{2}m^{-2}s^{-1}$ with increasing the light intensity up to 1,600 PPFD, but it was decreased at 2,000 PPFD. The highest photosynthetic rate was shown in L. fischeri var. spiciformis, followed by L. fischeri, and L. stenocephala. was the highest $27.39{\mu}mol\;CO_{2}m^{-2}s^{-1}$ among three species, followed by that of The differences in photosynthetic rates were significantly different among the species each measuring date. L. fischeri var. spiciformis was more adaptive species at the low elevated under-tree cultivated sites, such as, Sanchemaeul Dunnae-myeon Hoeyngseung-gun than L. fischeri and L. stenocephala.