• Fire Science and Engineering
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• v.34 no.1
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• pp.121-126
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• 2020

The aim of this study is to suggest ways to capitalize on the golden period for timely response to fire and emergency victims. To implement a system to effectively capitalize on the golden period, there is a need for policy measures as well as legal and social consensus. Precedent research has relentlessly mentioned the need for and feasibility of the priority traffic system for emergency vehicles. To this end, the present study involved an analysis of pilot cases of the priority traffic signal system for emergency vehicles introduced in a city during 26 days, from April 3 to 28, 2017. Out of 58 cases registered with the local 1-1-9 fire house, the number of cases that took advantage of the priority traffic system stood at 16 in response to fire and 11 to first-aid operations. Owing to the system, on average, the response time reduced by 3 min and 50 s in case of fire and by 3 min and 30 s for first aid. There were four complaints registered owing to traffic congestion, and the number of car accidents declined to one from six over the same period in the previous year. Based on these findings, it is safe to say that the priority traffic signal system would be effective for emergency vehicles to capitalize on the golden period if issues identified during the pilot run are resolved.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.1989-1992
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• 2014

Background: The aim of this study was to assess the response rates (clinical and pathological ) with docetaxel and epirubicin combination chemotherapy and its effect on outcome. Materials and Methods: We retrospectively analysed locally advanced breast cancer (LABC) patients who received NACT from January 2008 to December 2012 in our tertiary care centre. LABC constituted 37% of all breast cancer cases and 120 patients fulfilled the eligibility criteria. The regimens used for NACT were, six cycles of DEC (docetaxel $75mg/m^2$, epirubicin $75mg/m^2$, cyclophosphamide $50mg/m^2$ on Day 1, 3 weekly) and a sequential regimen (4 cycles of FEC, 5-flurouracil $600mg/m^2$, epirubicin $75mg/m^2$, cyclophosphamide $600mg/m^2$ followed by 4 cycles of docetaxel $85mg/m^2$). Results: The median age was 47 years (range 23-72). Ninety six ( 80 %) had T4 disease and 90% had clinically palpable lymph nodes at diagnosis. The median size of primary tumor at presentation was 5.9 cm. Hormone receptor positivity was seen in 55% and HER2/neu positivity, in 25%. Triple negative breast cancers constituted 25 % of the cases. The overall clinical response rate (complete or partial ) was 85% and pathological complete responses were obtained in 15%. Four cases defaulted, 5 patients died of treatment related toxicity and 15% developed febrile neutropenia on DEC. The median duration of follow up was 22 months. The median time to relapse was 20 months and the 3 year relapse free and overall survival rates were 50% and 70% respectively. Conclusions: LABC constituted 37% of all breast cancer cases at our institute. With NACT, pCR was seen in 15% of the cases. Sequential chemotherapy was better tolerated than concurrent anthracyline and taxane chemotherapy with a similar pCR.

• Radiation Oncology Journal
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• v.3 no.1
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• pp.41-50
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• 1985

63 patients who were irradiated with a goal of long term control among 101 patients with esophageal cancer seen during an 11 fears period between Jan, 1970 and Dec, 1980 at Yonsei Cancer Center in Seoul, Korea have retrospectively analysed. 52(82.5%) among the 63 Patients were confirmed to have epidermoid carcinoma in the histology. 46 cases(73.0%) except 17 cases of $T_1$, were locally or far advanced extension. Tumor dose of radical radiation in the management of esophageal cancer had delivered from 50 Gy to 74 Gys. 2 Gys daily fractions, between 5weeks and 8 weeks. After 1 month from the completion of radiation, 23 of the 63 patients had a repeat barium esophagogram for the assessment of tumor response, there had showed 7 cases of complete response and 15 cases of partial response. 45(71.4%) patients were followed up and the remaining 18 patients were lost to follow-up within 1 year after the completion of irradiation. Actuarial overall 3 and 5 years survival rate of all 63 Patients were 11.8% and 8.8%, respectively. The actuarial 3 and 5 years survival rates of 17 cases of $T_1$, esophageal cancer were 24.7% and 20.8%. Statistically, there was no significant difference in survival rate according to tumor location (p>0.05). Radical Radiotherapy, Esophageal Cancer

• Ocean Systems Engineering
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• v.9 no.4
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• pp.349-368
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• 2019

Triceratops is one of the new generations of offshore compliant platforms suitable for ultra-deepwater applications. Apart from environmental loads, the offshore structures are also susceptible to accidental loads. Due to the increase in the risk of collision between ships and offshore platforms, the accurate prediction of structural response under impact loads becomes necessary. This paper presents the numerical investigations of the impact response of the buoyant leg of triceratops usually designed as an orthogonally stiffened cylindrical shell with stringers and ring frames. The impact analysis of buoyant leg with a rectangularly shaped indenter is carried out using ANSYS explicit analysis solver under different impact load cases. The results show that the shell deformation increases with the increase in impact load, and the ring stiffeners hinder the shell damage from spreading in the longitudinal direction. The response of triceratops is then obtained through hydrodynamic response analysis carried out using ANSYS AQWA. From the results, it is observed that the impact load on single buoyant leg causes periodic vibration in the deck in the surge and pitch degrees of freedom. Since the impact response of the structure is highly affected by the geometric and material properties, numerical studies are also carried out by varying the strain rate, and the location of the indenter and the results are discussed.

• Structural Engineering and Mechanics
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• v.53 no.5
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• pp.897-919
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• 2015

In this study, the effects of ground shocks due to explosive loads on the dynamic response of historical masonry bridges are investigated by using the multi-point shock response spectrum method. With this purpose, different charge weights and distances from the charge center are considered for the analyses of a masonry bridge and depending on these parameters frequency-varying shock spectra are determined and applied to each support of the two-span masonry bridge. The net blast induced ground motion consists of air-induced and direct-induced ground motions. Acceleration time histories of blast induced ground motions are obtained depending on a deterministic shape function and a stationary process. Shock response spectrums determined from the ground shock time histories are simulated using BlastGM software. The results obtained from uniform and multi-point response spectrum analyses cases show that significant differences take place between the uniform and multi-point blast-induced ground motions.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.87-91
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• 2016

To investigate whether excision repair cross complementing-group1 (ERCC1) expression status could serve as a bio-predictor of response to platinum-based induction chemotherapy for head and neck cancers (HNCs) patients with a diagnosis of epithelial HNC were studied retrospectively. Paraffin embedded tumor samples of the patients were analyzed by reverse transcription-polymerase chain reaction (RT-PCR) to determine ERCC1 expression status and its correlation with response to platinum-based induction chemotherapy was investigated. Of 44 included patients, 33 were male (75%) and 11 were female (25%) with a mean age of 53 years. Some 36% of patients whose tumor samples had high ERCC1 expression showed no response to induction chemotherapy. The value for patients with low ERCC1 expression was 9% and the difference was statistically significant (p=0.03). The ERCC1 expression state did not significantly vary between patient groups according to sex, age, primary tumor site, and tumor and node stage. Our study indicates that ERCC1 expression status detected by RT-PCR might serve as a bio-predictor of response to platinum-based induction chemotherapy for epithelial HNCs.

• Wind and Structures
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• v.7 no.2
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• pp.89-106
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• 2004

The response of tall buildings to gust buffeting is usually evaluated assuming that the structural damping is of a viscous nature. In addition, when dampers are incorporated in the design to mitigate the response, their effect is allowed for increasing the building modal damping ratios by a quantity corresponding to the additional energy dissipation arising from the presence of the devices. Even though straightforward, this procedure has some degree of inaccuracy due to the existence of a memory effect, associated with the damping mechanism, which is neglected by a viscous model. In this paper a more realistic viscoelastic model is used to evaluate the response to gust buffeting of tall buildings provided with energy dissipation devices. Both cases of viscous and hysteretic inherent damping are considered, while for the dampers a generic viscoelastic behaviour is assumed. The Laguerre Polynomial Approximation is used to write the equations of motion and find the frequency response functions. The procedure is applied to a 25-story building to quantify the memory effects, and the inaccuracy arising when the latter is neglected.

• Journal of the Korea Safety Management & Science
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• v.19 no.1
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• pp.1-8
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• 2017

The current study aims to propose a reorganization plan for the national emergency management system to improve the current organizational structure for responding to national disasters and emergency situations. As a theoretical framework, the current study identified four key elements of successful disaster response systems: responsiveness, controllability, expertise, and devotedness. On the basis of the four key elements of disaster response systems, this study critically reviewed the current state of the organizational structure of the Korean national emergency response system by discussing the issues inherent in the current structure and by doing a comparative analysis of two high-profile national disaster cases-the Sewol ferry disaster in 2014 and the Gwangsan Rescue of buried people in 2013. Then, this study proposed the reorganization plan for the national disaster response system in which the NEMA is under direct control of the Prime Minister of Korea. It coordinates and controls the related government departments, such as the police, maritime police, and military during the national disaster and emergency situation. This study also proposed a reorganizational plan for the regional disaster response system in Korea. Finally, it was suggested that the status of firefighters should be elevated to the national public servant level in order to achieve organizational efficiency and solve existing problems that come from the current separated systems.

• Journal of Korean Association for Spatial Structures
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• v.19 no.3
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• pp.93-100
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• 2019

In this study, the retractable-roof spatial structure was chosen as the analytical model and a tuned mass damper (TMD) was installed in the analytical model in order to control the seismic response. The analysis model is mainly consisted of runway trusses (RT) and transverse trusses (TT), and the displacement response was analyzed by installing TMD on those trusses. The mass of the single TMD which is installed in the analytical model was set to 1% of the total structure mass and the total TMD mass ratio was set to be 8% or 6%. In addition, the mass of a single TMD was varied depending on the number of installations. As a result of analyzing the optimal number of installations of TMD, the displacement response was reduced in all cases compared to the case without TMD. Above all, the case with 8 TMDs was the most effective in reducing he displacement response. However, in this case, as the load on the upper structure of the retractable-roof spatial structure increases, the total mass ratio of TMD was maintained and the number of TMDs was increased to reduce the mass ratio of one TMD.

• Nuclear Engineering and Technology
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• v.51 no.7
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• pp.1791-1798
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• 2019

Instrumentation and Control (I&C) systems of nuclear power plants (NPPs) have been continuously digitalized. These systems have a critical role in the operation of nuclear facilities by functioning as the brain of NPPs. In recent years, as cyber security threats to NPP systems have increased, regulatory and policy-related organizations around the world, including the International Atomic Energy Agency (IAEA), Nuclear Regulatory Commission (NRC) and Korea Institute of Nuclear Nonproliferation and Control (KINAC), have emphasized the importance of nuclear cyber security by publishing cyber security guidelines and recommending cyber security requirements for NPP facilities. As described in NRC Regulatory Guide (Reg) 5.71 and KINAC RS015, challenge response authentication should be applied to the critical digital I&C system of NPPs to satisfy the cyber security requirements. There have been no cases in which the most robust response authentication technology like challenge response has been developed and applied to nuclear I&C systems. This paper presents a challenge response authentication mechanism for a Programmable Logic Controller (PLC) system used as a control system in the safety system of the Advanced Power Reactor (APR) 1400 NPP.