• Journal of Yeungnam Medical Science
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• v.21 no.2
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• pp.215-223
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• 2004

Silicone is widely used for medical purposes in breast augmentation and other cosmetic procedures. Illegal injections of silicone in human beings might have adverse effects and one of the serious problems is a silicone embolism. We experienced five cases of unusual respiratory difficulties after an injection of liquid silicone in the breast, vagina, uterus, and hip. They were all young adult females, who were previously healthy. One of them died after the injection. The three remaining patients were admitted because of dyspnea, coughing, chest discomfort and bilateral pulmonary infiltration after the silicone injection. A transbronchial lung biopsy and autopsy disclosed many oil like materials filling the alveolar septal capillaries. Three patients underwent a computed tomogram (CT), which revealed multifocal airspace consolidations at the peripheral and nondependent portions of both lungs, which is a different finding from other thromboembolisms. Lung scans of the disclosed abnormalities were compatible with silicone induced pulmonary embolism.

• Clinical and Experimental Pediatrics
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• v.45 no.3
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• pp.401-405
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• 2002

Mycoplasma pneumoniae(M. pneumoniae) is the leading cause of pneumonia in school-age children and young adults. The clinical courses are usually mild but recently, severe cases were reported such as lung abscess, Swyer-James syndrome and adult respiratory distress syndrome. Spontaneous pneumothorax associated with M. pneumoniae infection is rare. Carlisle reported a 6-year-old patient with bilateral spontaneous pneumothorax associated with M. pneumoniae infection and Koura also reported a 18-year-old girl with repeated. M. pneumoniae pneumonia with recurrent pneumothorax. We experienced bilateral spontaneous tension pneumothorax and subcutaneous emphysema associated with M. pneumoniae infection in a 6-year-old boy who presented with dyspnea, chest pain, and neck swelling. We reported it as the first case in Korea.

• Journal of Chest Surgery
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• v.26 no.7
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• pp.526-531
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• 1993

Sixty-one consecutive patients with coronary artery bypass graft for myocardial revascularization were retrospectively reviewed to analyze various pattern of postoperative complication and death during hospital stay from Nov. 1988 to Oct. 1992. Fortytwo of the patients were male and nineteen female. The mean age was 56 and 51 years in male and female. Preoperative diagnosises were unstable angina in 14 of patients, stable angina in 28, postmyocardial infarction state in 15, and state of failed percutaneous transluminal coronary angioplasty in 4. 141 stenosed coronary arteries were bypassed with use of 20 pedicled internal mammary artery and 124 reversed saphenous vein grafts. Postoperative complications and perioperative death were as follows: 1. Of 61 patients undergoing operation, peri and postoperative over all complication occured in 15 patients [ 25% ]; newly developed myocardial infarction in 4, intractable cardiac arrhythmia including atrial fibrillation and frequent ventricular premature contraction in 3, bleeding from gastrointestinal tract in 2, persistent vegetative state as a sequele of brain hypoxia in 1, wound necrosis in 1, left hemidiaphragmatic palsy in 3 and poor blood flow through graft in 2. 2. Operative mortality was 8%[5 patients]. 3 out of these died in operating room; 1 patient by bleeding from rupture of calcified aortic wall, 1 by air embolism through left atrial vent catheter, 1 by low cardiac output syndrome. 2 patients died during hospital stay; 1 by acute respiratory distress syndrome with multiuple organ failure, 1 by brain death after delayed diagnosis of pericardial tamponade.

• Journal of Chest Surgery
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• v.24 no.11
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• pp.1098-1106
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• 1991

Atelectasis may be defined as collapse of the lung due to absence of air within the alveoli. It may involve anatomic segments, lobes, or whole lungs but also may be a diffuse miliary process, as in the adult respiratory distress syndrome. The key to treatment are the anticipation and prevention of atelectasis in various clinical situations, the recognition and treatment of underlying disease, and the prompt initiation of vigorous treatment once atelectasis is found. Repeated assessment by physical examination is necessary to determine the presence of atelectasis and its response to treatment. During the period of January, 1981 to October, 1990, 100 patients with atelectasis were treated in the department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital. There were 70 males and 30 females ranging from 3 days to 79 years of age. The occurrence ratio of right to left side was 2.1 : 1. The underlying pathologic lesions of atelectasis were pneumonia with effusion(28), lung ca.(24), pulmonary tuberculosis(24), and chronic empyema(9), The treatment procedure for atelectasis were closed thoracostomy in 26 cases, ressection in 21 cases, therapeutic bronchoscopy in 14 cases and etc.

• Journal of Chest Surgery
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• v.23 no.1
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• pp.128-136
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• 1990

A Clinical analysis was performed on 717 cases of the chest trauma experienced at department of thoracic and cardiovascular surgery, Soonchunhyang Chunan Hospital from Mar. 1985 to Jun. 1989. 1. The sex ratio was 2.89:1 with male predominance. The patients in 75 % of total cases was between 3rd to 5th decade. 2. The most common causes were traffic accident in non-penetrating thoracic injury and stab wound by knife in penetrating injury. 3. The hemothorax, pneumothorax and hemopneumothorax were observed in 306 cases[42.7 %]. 4. The left thorax was the preferred site of penetrating and non-penetrating thoracic injury. The rib fracture was prevalent between 4th to 8th rib. 5. The open thoracotomy was performed in 55 cases[7.7 %] 6. The overall mortality was 3.07 %[22 cases] and causes of death were hypovolemic shock, adult respiratory distress syndrome, sepsis, disseminated intravascular coagulation, renal failure and pneumonia.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.230-230
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• 1994

Human leukocyte elastase(HLE)는 폐와 피부, 혈관등의 Connective tissue의 주요 구성물인 elastin을 분해하는 효소로써, 백혈구의 식균작용에도 관여한다. 그러나 이효소가 과다하게 분비되면 pulmonary emphysema와 adult respiratory distress syndrome, rheumatoid arthritis를 유발한다고 알려지고 있다. 지금까지 HLE억제제로 시판되는 의약품은 없으나, 최근에 Cephalosporin유도체가 이 효소의 억제제로 우수한 효과가 있다는 보고가 있은 후, HLE억제제로써 이들의 유도체가 개발되고 있다. 연구자들은 다음일반식에서 2번과 3번위치에 치환기를 도입시킨 수종의 Cephalosporin Sulfone의 유도체들을 합성하고. 이들의 HLE억제 효과를 Spectrophotometerqkdtlr을 이용하여 측정하였다. 합성화합물증 몇가지는 우수한 HLE억제효과를 보여주었고, 2번위치에 diphenylcyclopropyl ring과 같은 부피가 큰 치환체를 도입하면 효소억제력이 증가되었다.

• Journal of Chest Surgery
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• v.10 no.1
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• pp.49-52
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• 1977

Congenital lobar emphysema is one of the many causes of the respiratory distress syndrome in infant and an unusual condition barely mentioned before 1949, and only 166 cases were reported till 1967 in English literature This report describes a one-month-old boy who had a congenital middle lobar emphysema. The middle lobectomy was the operation for this case with complete cure.

• Pediatric Infection and Vaccine
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• v.7 no.2
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• pp.245-249
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• 2000

Listeria monocytogenes is one of the important causes of neonatal sepsis and listerial neonatal infection manifests in two forms : Early-onset sepsis syndrome, associated with spontaneous abortion, still birth, preterm labor, granulomatosis infantiseptica, respiratory distress, sepsis, hemodynamic compromise and late-onset listerosis mainly associated with meningitis. Cases of neonatal listerosis reported in Korea have been rare and all were full term newborns. We, herein, report a case of early-onset sepsis due to L. monocytogenes in a extremely low birth weight infant who were born in a critical condition and succumbed in the second day of life despite the intensive care.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.05a
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• pp.539-542
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• 2022

신생아 호흡곤란 증후군은 주로 미숙아에게 발생하는 호흡기 질환으로, 특징적 영상 소견 및 다른 검사 소견을 바탕으로 진단된다. 본 논문은 기계 장치 등 외부 요소의 영향을 최소화하고자 폐 영역을 분할하여 신생아 호흡곤란 증후군을 진단하는 기법을 제안한다. 분할에는 UNet 구조를 사용하고 진단에는 EfficientNet-B5를 사용하여 최종적으로 신생아 호흡곤란 증후군의 진단 정확도 0.852를 달성하였다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.06a
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• pp.1181-1183
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• 2022

신생아 호흡곤란증후군(RDS, Respiratory Distress Syndrome)은 미숙아 사망의 주된 원인 중 하나이며, 이 질병은 빠른 진단과 치료가 필요하다. 소아의 x-ray 영상을 시각적으로 분석하여 RDS 의 판별을 하고 있으나, 이는 전문의의 주관적인 판단에 의지하기 때문에 상당한 시간적 비용과 인력이 소모된다. 이에 따라, 본 논문에서는 전문의의 진단을 보조하기 위해 심층 신경망을 활용한 소아 RDS/nonRDS 판별 방법을 제안한다. 소아 전신 X-ray 영상에 폐 영역 분할을 적용한 데이터 세트와 증강방법으로 추가한 데이터 세트를 구축하며, RDS 판별 성능을 높이기 위해 ImageNet 으로 사전학습된 DenseNet 판별 모델에 대해 구축된 데이터 세트로 추가 미세조정 학습을 수행한다. 추론 시 입력 X-ray 영상에 대해 MSRF-Net 으로 분할된 폐 영역을 얻고 이를 DenseNet 판별 모델에 적용하여 RDS 를 진단한다. 실험결과, 데이터 증강과 폐 영역을 분할을 적용한 판별 방법이 소아전신 X-ray 데이터 세트만을 사용하는 것과 비교하여 3.9%의 성능향상을 보였다.