• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권3호
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• pp.325-340
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• 2008

The purpose of this study was to evaluate the artificial dental plaque by Streptococcus mutans on 4 different implant surfaces. In this study, the specimens were divided into 4 groups according to implant surface treatment. Uncoated implant group(n=5) which has an uncoated, smooth surfaced implant(Osstem, Korea), SLA implant group(n=5) which has an sandblasted large grit and acid-etched surface implant(Bicon, USA). Oxidized implant group(n=5) which has an oxidized surfaced implant (Osstem, Korea), and RBM implant group(n=5) which has resorbable blasting media(RBM) surfaced implant(Osstem, Korea). Acquired pellicle by human saliva and dental plaque by Streptococcus mutans were made on each implant surface. To analyze the plaque condition on implants surfaces, cell count and optical density were taken as a microbiologic method, and SEM(Scanning Electronic Microscope) findings was also taken for evaluation of surface condition. The following results were obtained. 1. Cell counting results of artificial dental plaque were Uncoated group($658.0{\pm}102.0$), RBM group($878.0{\pm}170.0$), SLA group ($946.0{\pm}42.0$), Oxidized group($992.0{\pm}40.0$), and there was difference between Oxidized group and Uncoated implant group(p<0.05). In case of modified cell counting results by v/w% were RBM group($197.8{\pm}45.2$), Oxidized group($207.04{\pm}8.34$), Uncoated group($261.6{\pm}40.6$), SLA group($315.4{\pm}14.0$), and there was difference between RBM group and SLA group(p<0.05). 2. Optical density results of artificial dental plaque after ultrasonic treatment was that there was difference among groups, and optical density of RBM group was higher than that of Uncoated group(p<0.05). In case of modified optical density results by v/w%, there was difference among groups, and the modified optical density of Uncoated group and SLA group was higher than those of Oxidized group and RBM group(P>0.05). 3. SEM findings of artificial dental plaque on the surfaces of implant as follows; there were artificial dental plaque on the surfaces of all test implants. Streptococcus mutans and by-product were observed at 10,000 times magnified condition on all test implants. Adhesion area of artificial dental plaque was about 1/2 of total surface after 24 hours incubate at $37^{\circ}C$. These results showed that there were differences among implant surfaces on the growth of Streptococcus mutans, and bacteria and by-product were covered about 1/2 area of total implant surfaces at 24 hours incubate at $37^{\circ}C$.

• 대한치과보철학회지
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• 제44권5호
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• pp.594-605
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• 2006

Statement of problem: Modification of titanium implant surface has potential to ensure clinically favorable performance that several surface modification technologies have been introduced. Among the methods. anodizing method and sol-gel hydroxyapatite coating method have gained much interest due to its roughness and chemical composition of the coating layer, but more of its biocompatibility result is required. Purpose : The purpose of this study was to compare bone-implant interface shear strength of four different surface treated implants as time elapsed. Resonance frequency analysis(RFA) and removal torque measurement methods were employed to measure implant stability at one week and six week after implantation. Material and method: A total of 80 screw-shaped implant [20 machined, 20 resorbable media blasted(RBM), 20 anodized, and 20 anodized+hydroxyapatite sol-gel coated] were prepared, and one of each group was implanted in the tibia of a New Zealand white rabbit that total 20 of them were used. In order to test the implant stability and implant-tissue interface contact changing in the bone bed, each 10 rabbit were sacrificed 1 week and 6 week later while resonance frequency and removal torque were measured. One-way analysis of variance and the Tukey test were used for statistical analysis. Results : The results were as follows. 1. There was no statistically significant difference of implant stability quotients(ISQ) value in RFA between individual groups after 1 week of implantation and 6 weeks(p>0.05). But, there was statistically significant increase of ISQ value in 6 weeks group compared to 1 week group(p<0.05). 2. There was no statistically significant difference in removal torque analysis between individual groups after 1 week of implantation and 6 weeks(p>0.05). but there was statistically significant increase in all 4 groups after 6 weeks compared to 1 week later(p<0.05). 3. There was no statistically significant difference in removal torque analysis between anodized group and HA coating after anodic oxidation 6 weeks later(p>0.05), but significant difference was appeared in both groups compared to RBM group and smooth-machined group(p<0.05). Conclusions : It can be suggested that changes in surface characteristics affect bone reactions. Anodized and anodized+hydroxyapatite sol-gel coating showed significantly improved bone tissue response to implants, but further study on the effect of hydroxyapatite dissolution is needed.

• 대한치과보철학회지
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• 제44권3호
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• pp.314-324
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• 2006

Statement of problem. Osseointegration is important mechanism of dental implant but it is not easy to evaluate. Indirect measurement is non-invasive and clinically applicable but they need more study about correlation between indirect values and degree of osseointegration. Purpose. The aims of this study were to evaluate the coefficient of correlation between indirect measurement and direct measurement under different healing time, and assessment of effect of initial insertion torque to the implant stability. Material and Methods. 20 rabbits received 3 implants on each side of tibia. Three kinds of implants (machined surface implant, Sandblasted with Large grit and Acid etched implant, Resorbable Blast Media treated implant) were used. During the surgery implant insertion torque were measured with $Osseocare^{TM}$. After the 1, 4, 8, 12 weeks of healing time, animals were sacrificed and stability values (Implant Stability Quotient with $Osstell^{TM}$, removal torque with torque gauge) were measured. Results. The Bone quality of rabbit tibia was classified into 2 groups according to the insertion torque. Resonance frequency analysis (ISQ) and removal torque showed positive correlation until $4^{th}$ week (r=0.555, p=0.040). After $8^{th}$ week (r=0.011, p=0.970) the correlation became weak and it turned negative at $12^{th}$ week (r=-0.074, p=0.801). Insertion torque and ISQ showed changing correlation upon the healing time ($1^{st}$ week: r=0.301, p=0.033, $4^{th}$ week: r=-0.429, p=0.018, $8^{th}$ week: r=0.032, p=0.865, $12^{th}$ week: r=-0.398, p=0.029). Insertion torque and removal torque has positive correlation but it was not statistically significant ($1^{st}$ week: r=0.410, p=0.129, $4^{th}$ week: r=0.156, p=0.578, $8^{th}$ week: r=0.236, p=0.398, $12^{th}$ week: r=0.260, p=0.350). Conclusion. In this study, bone quality may affect the degree of osseointegration positively during healing time and correlation between ISQ and degree of osseointegration can be different according to the healing time and bone quality.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제31권3호
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• pp.237-242
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• 2009

Implant-supported fixed and removable prostheses provide a proper treatment modality with reliable success. The SS $II^{(R)}$ Implants is a one-stage nonsubmerged threaded titanium implants with Resorbable Blasting Media (RBM) surface developed by Osstem company (Busan, Korea) in October of 2002. This study is to evaluate the survival rate of the SS $II^{(R)}$ Implants for 4 years using radiographic parameters and to review the retrieved implants by the cytotoxicity tests. Since September 2003, 439 SS $II^{(R)}$ implants had been used for 173 patients at Ewha Womans University Medical Center in Korea. Patients consisted of 91 females (52.6 %) and 82 males (47.4 %). The patients' mean age was $42\;{\pm}16$ years, ranging from 21 to 83 years. The follow-up period ranged from 9 to 46 months (mean F/U $24.2\;{\pm}\;10.2$ months). The results are as follows; 1. Of 439 implants, 17 implants were removed and 4-year cumulative survival rate was 96.1%. 2. 82.3% of 17 failed implants were founded during healing phase, and 94.1% of failed fixtures were removed within 5 months after implantation. 3. Crestal bone around the implants was resorbed to 1 mm in 89.0%, to 1 - 2 mm loss of the marginal bone in 8.3%, and the bone loss over 2 mm was occurred in 2.7%. 4. Microscopic examination of the retrieved implants disclosed Grade 0 cytotoxicity in 4 and Grade 1 cytotoxicity in 2 of 6 groups divided according to LOT numbers. Inhibition rate with optical density was acceptable as low as ISO standard.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제29권5호
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• pp.383-393
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• 2007

The aim of the present study is to investigate the effect of anodized surface of osseointegration implants by using of resonance frequency analysis (RFA) and histomorphometric analysis. A total of 96 screw-shaped implants were devided into 4 groups. Seventy-two implants were prepared by electrochemical oxidation with 3 different ways; Group 1 (n=24) were prepared at galvanostatic mode in 0.25M sulfuric acid and phosphoric acid, Group 2 (n=24) were prepared at galvanostatic mode in calcium glycerophosphate and calcium acetate, and Group 3 (n=24) were prepared at galvanostatic mode in 0.25M sulfuric acid and phosphoric acid followed by Calcium metaphosphate(CMP) coating. Control group (n=24) were the RBM surfaced implants. The implants were placed in the mandibles of 12 mini pigs. Bone tissue responses were evaluated by resonance frequency analysis(RFA) and histomorphometric analysis that were undertaken at 2, 4 and 6weeks after implant placement. The following result were obtained. 1. Twenty-two of 96 implants (4 in control group, 5 in group 1, 7 in group 2, and 6 in group 3) were failed due to faliure of osseoitegration. The failure rate of osseointegration was 22.9%. 2. The mean values of RFA in control, group 2 and groups 3 showed the similar values, but there was no significant difference among groups. 3. Histomorphometric evaluation demonstrated significantly higher bone-to-implant contact ratio in group 2 at 3 and 4 weeks after implant placement than other groups (p<0.05), but there was no significant difference among groups at 6weeks after implant placement.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제29권4호
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• pp.301-308
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• 2007

Purpose: This study was performed to compare and evaluate the effect of recipient site depths and diameters of the drills on the primary stability of implant in pig's ribs. Materials and methods: An intact pig's rib larger than 8 mm in width and 20 mm in height; RBM(resorbable blasting media) surface blasted ${\phi}3.75mm$ and 8.0 mm long USII Osstem Implants (Osstem Co., Korea) were used. To measure the primary stability, $Periotest^{(R)}$ (Simens AG, Germany) and $Osstell^{TM}$ (Model 6 Resonance Frequency Analyser: Integration Diagnostics Ltd., Sweden) were used. They were divided into 6 groups according to its recipient site formation method: D3H3, D3H5, D3H7, D3.3H3, D3.3H5, D3.3H7. Each group had, as indicated, 10 implants placed, and total 60 implants were used. The mean value was obtained by 4-time measurements each on mesial, distal, buccal, and lingual side perpendicular to the long axis of the implant using $Periotest^{(R)}$ and $Osstell^{TM}$. For statistical analysis one-way ANOVA was used to compare the mean value of each group, and the correlation between placement depths and the primary stability, and that of measuring instruments was analyzed using SPSS 12.0. Results: The primary stability of the implants increased as the placement depths increased (p<0.05), and showed a proportional relationship (p<0.01). The primary stability increased when the diameter of the recipient site was smaller than that of the implant but with no statistical significance. There was a strong correlation between $Osstell^{TM}$ and $Periotest^{(R)}$ (p<0.01). Conclusion: These results suggest that increasing the placement depth of implants enhances the primary stability of implant.

• 구강회복응용과학지
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• 제23권4호
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• pp.327-336
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• 2007

Fixture의 안정도를 평가하는 장비인 Osstell Mentor와 기존 Osstell과의 비교 시험 및 측정환경에 따른 노이즈 발생 시험 결과를 통해 다음과 같은 결과를 얻었다. 1. US II Fixture와 SS II Fixture의 ISQ 값을 측정한 1차 검증에서는 Osstell과 Osstell Mentor의 ISQ 값 경향의 차이가 크게 나타나지 않음을 확인하였다. 2. SS II Fixture를 얕게 매식한 것과 정상적인 매식한 것의 ISQ 값 비교를 한 2차 검증에서는, Osstell과 Osstell Mentor 모두 매식 깊이에 따른 동일한 경향의 결과를 보였다. 3. 3차 검증에서는 골질별로 Osstell과 Osstell Mentor의 ISQ 값이 일정한 경향을 보이는 것을 확인하였고, 특히 Osstell Mentor 장비는 Osstell 장비보다 사용함에 있어서 편리성이 뛰어나다고 판단된다. 또한 ISQ 값을 100% 신뢰하기는 어렵지만 Osstell Mentor를 임상 및 실험에 적용하는데 있어서는 문제가 없을 것으로 판단된다. 4. 측정환경에 따라 전자파를 발생시키는 환경이 존재하면 노이즈가 발생할 수 있으나, 실제 측정결과 휴대폰이 작동 중인 환경을 제외하고는 노이즈가 발생하지 않았다. 실제 치과 내에서의 사용에서도 노이즈는 발생하지 않음을 확인하였다. 5. 비교적 안전하게 장치를 장착 및 탈착 할 수 있어 측정과정에 의해 발생되는 임플란트와 주위골에 대한 잠재적 위험도가 낮고 측정위치에 따른 오차가 적어 임상적으로 불리한 상황과 다양한 환경에서의 임플란트 안정성 측정이 가능해 임상적 활용도가 높다고 판단된다.

• Journal of Periodontal and Implant Science
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• 제38권3호
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• pp.413-428
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• 2008

Purpose: Given the predictability of dental implant procedure from the studies of successful osseointegration, implant dentistry is often the treatment of choice to replace missing teeth in edentulous patient instead of the fixed prosthesis or removable denture. The $Renova^{(R)}$ dental implant has a RBM(Resorbable Blast Media) surface, internal hex prosthetic connection and a tapered design. At this study gives the analysis of the implant and the short term survival rate of the implant. Material and Methods: In this study, a multilateral analysis was performed on the subjects undergoing placement with $Renova^{(R)}$ implant between August 2006 and February 2008 in Yonsei University dental hospital. 96 implants were placed in 56 patients and they were surveyed for cumulative survival rate. Among them 78 implants in 44 patients were surveyed for the rest analyses. Result: 1. The cumulative survival rate was 96.88% of 96 implants in 56 patients. 2. The mean marginal bone loss was 0.803mm and the marginal bone loss in augmentation group has higher value than the marginal bone loss in non augmentation group. 3. The health scale for the implants were 87% in success group, 9% in satisfactory survival group, 1% in compromised survival group, and 3% in failure group. 4. Two implants placed in poor bone posterior area by 2-stage failed during prosthetic procedure. Conclusion: $Renova^{(R)}$ dental implant showed high cumulative survival rate in installation on partial edentulous ridge and could be a predictable implant system.

• 구강회복응용과학지
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• 제33권3호
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• pp.178-188
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• 2017

목적:본 연구에서는 새로 개발된 다이오드 레이저 제품을 이용하여 레이저 파워에 따른 온도변화와 박테리아 멸균 비교실험을 통하여 기존 제품과의 임플란트 주위염치료에 대한 효과를 비교 실험하였다. 연구 재료 및 방법: 808 nm Diode laser와 810 nm Diode laser를 사용하여 디스크에 레이저를 60초간 조사하였으며, 출력은 1 - 2.5 W로 설정하였다. 온도측정 모듈과 온도측정 프로그램을 이용하여 disc 표면온도변화를 측정하였다. 또한, SLA, RBM이 코팅된 disc에 bacteria 도포 후, 808 nm Diode laser를 30초간 조사하였으며, 출력은 0.5 - 3 W로 설정하였다. 결과: 808 nm, 810 nm 두 장치 모두 출력이 증가함에 따라 온도 상승폭은 증가하였다. 모든 조건에서 810 nm laser를 조사하였을 때 초기온도상승속도, 하강속도 및 전후의 온도변화량은 808 nm laser 보다 높았다. 레이저 조사 후 티타늄 디스크 표면의 변화는 두 레이저 모두에서 관찰되지 않았다. Bacteria가 도포된 디스크에 808 nm laser를 조사한 결과, 출력이 증가 함에 따라 살균효과가 증가하는 것을 확인하였다. 결론: Diode laser를 임상에 적용하는 경우, 동일한 출력에서 온도의 변동폭이 적고 최대 상승온도가 낮은 808 nm laser가 환자에 안전할 것으로 사료된다. 하지만 실제로 임상에 적용하기 위해서는 보다 다양한 안전성평가를 실시하여 장비에 대한 신뢰성을 확보하여야 할 것이다.