• Journal of the Korean Magnetic Resonance Society
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• v.8 no.2
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• pp.96-107
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• 2004

We prepared two oligonucleotides containing same base pairing, but different base sequence in the middle region, d(CGAATTCG) and d(CGTATACG). NMR and UV absorbance data represented that such variation in base sequence could cause a significant difference in melting temperature and dynamics between d(CGAATTCG)$_2$ and d(CGTATACG)$_2$ duplexes, which are regarded to be associated with the stacked structure and the width of the minor groove of them. The latter showed poor stability compared to the former, because of poor stacking of bases. And berenil could bind to the minor groove of d(CGAATTCG)$_2$ which is relatively narrow, more strongly than d(CGTATACG)$_2$ and this gave rise to large improvement in thermal stability of the d(CGAATTCG)$_2$ duplex, compared to d(CGTATACG)$_2$.

• Korean Journal of Radiology
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• v.22 no.2
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• pp.198-212
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• 2021

Placenta accreta spectrum (PAS) is an abnormal placental adherence or invasion of the myometrium or extrauterine structures. As PAS is primarily staged and managed surgically, imaging can only guide and facilitate diagnosis. But, imaging can aid in preparations for surgical complexity in some cases of PAS. Ultrasound remains the imaging modality of choice; however, magnetic resonance imaging (MRI) is required for evaluation of areas difficult to visualize on ultrasound, and the assessment of the extent of placenta accreta. Numerous MRI features of PAS have been described, including dark intraplacental bands, placental bulge, and placental heterogeneity. Failure to diagnose PAS carries a risk of massive hemorrhage and surgical complications. This article describes a comprehensive, step-by-step approach to diagnostic imaging and its potential pitfalls.

• Wind and Structures
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• v.6 no.2
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• pp.151-164
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• 2003

On the basis of the first Lyapunov stability theory, this paper develops a dynamic stability criterion for elastic structural systems under arbitrary dynamic loads, and shows the stability criterion using energy variation. After the dynamic stability criterion is validated through a classic example, it is used for the dynamic stability investigation of practical guyed masts under random wind loads. The criterion is reliable, simple and of advantage for structures with large number of elements and nodes. The slack guys and internal resonance between guys and mast are two main factors which induces the dynamic instability of guyed masts, at the same time, some dynamic stability characteristics of guyed masts are found.

• Applied Science and Convergence Technology
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• v.25 no.2
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• pp.36-41
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• 2016

Similarity and diversity of various quantum ring structures are investigated by classifying energy dispersions of three different structures: an electrostatic quantum ring, a magnetic quantum ring, and a magnetic-electric quantum ring. The wave functions and the eigenenergies of a single electron in the quantum ring structures are calculated by solving the Schrdinger equation without any electron-electron interaction. Magnetoconductance is studied by calculating a two-terminal conductance while taking into account the backscattering via the resonance through the states of the quantum rings at the center of a quasi-one dimensional conductor. It is found that the energy spectra for the various quantum ring structures are sensitive to additional electrostatic potentials as well as to the effects of a nonuniform magnetic field. There are also characteristics of similarity and diversity in the energy dispersions and in the single-channel magnetoconductance.

• Bulletin of the Korean Chemical Society
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• v.11 no.4
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• pp.313-317
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• 1990

Geometries for several representative quinolone carboxylate type antibacterials have been calculated by computer graphics/molecular mechanics energy minimization procedures using both MM2 and AMBER force fields. The calculated geometries were found to be in reasonable agreements with the corresponding X-ray crystal structures. It has been pointed out that notwithstanding the weaknesses associated with calculating the resonance and hydrogen bonding contributions, the employed methods are capable of generating credible ring geometries and torsional angle dispositions of N(1)-ethyl and 3-carboxylate substituents of the quinolones.

• Journal of the Korean Magnetic Resonance Society
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• v.16 no.2
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• pp.172-184
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• 2012

The prokaryotic molecular chaperone Hsp33 achieves its holdase activity upon response to oxidative stress particularly at elevated temperature. Despite many structural studies of Hsp33, which were conducted mainly by X-ray crystallography, the actual structures of the Hsp33 in solution remains controversial. Thus, we have initiated NMR study of the reduced, inactive Hsp33 monomer and backbone NMR assignments were obtained in the present study. Based on a series of triple resonance spectra measured on a triply isotope-[$^2H/^{13}C/^{15}N$]-labeled protein, sequence-specific assignments of the backbone amide signals observed in the 2D-[$^1H/^{15}N$]TROSY spectrum could be completed up to more than 96%. However, even considering the small portion of non-assigned resonances due to the lack of sequential connectivity, we confirmed that the total number of observed signals was quite smaller than that expected from the number of amino acid residues in Hsp33. Thus, it is postulated that peculiar dynamic properties would be involved in the solution structure of the inactive Hsp33 monomer. We expect that the present assignment data would eventually provide the most fundamental and important data for the progressing studies on the 3-dimensional structure and molecular dynamics of Hsp33, which are critical for understanding its activation process.

• Wind and Structures
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• v.32 no.1
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• pp.31-46
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• 2021

The current research deals with, stability/instability and cylindrical composite nano-scaled shell's resonance frequency filled by graphene nanoplatelets (GPLs) under various thermal conditions (linear and nonlinear thermal loadings). The piece-wise GPL-reinforced composites' material properties change through the orientation of cylindrical nano-sized shell's thickness as the temperature changes. Moreover, in order to model all layers' efficient material properties, nanomechanical model of Halpin-Tsai has been applied. A functionally modified couple stress model (FMCS) has been employed to simulate GPLRC nano-sized shell's size dependency. It is firstly investigated that reaching the relative frequency's percentage to 30% would lead to thermal buckling. The current study's originality is in considering the multifarious influences of GPLRC and thermal loading along with FMCS on GPLRC nano-scaled shell's resonance frequencies, relative frequency, dynamic deflection, and thermal buckling. Furthermore, Hamilton's principle is applied to achieve boundary conditions (BCs) and governing motion equations, while the mentioned equations are solved using an analytical approach. The outcomes reveal that a range of distributions in temperature and other mechanical and configurational characteristics have an essential contribution in GPLRC cylindrical nano-scaled shell's relative frequency change, resonance frequency, stability/instability, and dynamic deflection. The current study's outcomes are practical assumptions for materials science designing, nano-mechanical, and micromechanical systems such as micro-sized sensors and actuators.

• Steel and Composite Structures
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• v.48 no.3
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• pp.335-351
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• 2023

This research studies the primary resonance and nonlinear vibratory responses of multilayer functionally graded shallow (MFGS) shells under external excitations. The shells considered with functionally graded porous (FGP) core and resting on two types of nonlinear viscoelastic foundations (NVEF) governed by either a linear model with two parameters of Winkler and Pasternak foundations or a nonlinear model of hardening/softening cubic stiffness augmented by a Kelvin-Voigt viscoelastic model. The shells considered have three layers, sandwiched by functionally graded (FG), FGP, and FG materials. To investigate the influence of various porosity distributions, two types of FGP middle layer cores are considered. With the first-order shear deformation theory (FSDT), Hooke's law, and von-Kármán equation, the stress-strain relations for the MFGS shells with FGP core are developed. The governing equations of the shells are consequently derived. For the sake of higher accuracy and reliability, the P-T method is implemented in numerically analyzing the vibration, and the method of multiple scales (MMS) as one of the perturbation methods is used to investigate the primary resonance. The results of the present research are verified with the results available in the literature. The analytical results are compared with the P-T method. The influences of material, geometry, and nonlinear viscoelastic foundation parameters on the responses of the shells are illustrated.

• Steel and Composite Structures
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• v.51 no.4
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• pp.457-471
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• 2024

In this research, for the first time the instability boundaries for a spinning shaft reinforced with graphene nanoplatelets undergone the principle parametric resonance are determined and examined taking into account the gyroscopic effect. In this respect, the extracted equations of motion in our previous research (Ref. Asadi et al. (2023)) are implemented and efficiently upgraded. In the upgraded discretized equations the effect of the Rayleigh's damping and the varying spinning speed is included that leads to a different dynamical discretized governing equations. The previous research was about the free vibration analysis of spinning graphene-based shafts examined by an eigen-value problem analysis; while, in the current research an advanced mechanical analysis is addressed in details for the first time that is the dynamics instability of the aforementioned shaft subjected to the principal parametric resonance. The spinning speed of the shaft is considered to be varied harmonically as a function of time. Rayleigh's damping effect is applied to the governing equations in order to regard the energy loss of the system. Resorting to Bolotin's route, Floquet theory and β-Newmark method, the instability region and its accompanied boundaries are defined. Accordingly, the effects of the graphene nanoplatelet on the instability region are elucidated.

• Journal of the Society of Naval Architects of Korea
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• v.40 no.4
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• pp.46-52
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• 2003

In ship structures, many parts are in contact with inner or outer fluid as stern, ballast and oil tanks. Fatigue damages can be sometimes observed in these tanks which seem to be caused by resonance. Tank structures in ships are in contact with water and the vibration characteristics are strongly affected by the added mass of containing water. Therefore it is important to predict vibration characteristics of tank structures. In order to estimate the vibration characteristics, the fluid-structure interaction problem has to be solved precisely. In the present paper, we have developed a numerical tool of vibration analysis of 3-dimensional tank structures using finite elements for plates and boundary elements for water region. To verify the present analysis, we have made an experiment for vibration characteristics of a tank with elastic opposite panels. And the added mass effect of containing water and the effect of structural constraint between panels are investigated numerically and discussed.