• Journal of Microbiology
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• 제39권1호
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• pp.62-66
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• 2001

Unlike eukaryotic efflux pumps energized by ATPase bacterial efflux pumps are energized by the proton motive force. That is the reason why CCCP, an inhibitor of proton motive forcer is widely used to study the bacterial efflux pump. In many cases, efflux systems have been observed only in quinolone-resistant bacteria. Most of the quinolone-susceptible strains have been found to maintain little efflux pump. However some susceptible bacteria skewed the increased intracellular quinolone concentration only at a low concentration (0.01 or 0.1 mM) but net at a high concentration (1 mM) of CCCP. If bacterial cells were killed at high concentrations of CCCP and lost the integrity of their membranes, the intracellular quinolone would leak out from cells with no efflux system. The efflux pump system in the quinolone-susceptible strains could net be detected at the same concentration used for resistant bacteria. To test this hypothesist the intracellular quinolone concentration in the quinolone-susceptible and -resistant strains of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was assayed at various concentrations of CCCP. Since the effect of CCCP is very rapid, the survival of bacteria was observed by assaying the DNA synthesis in 5 min. In the case of E. coli, but not P. aeruginosa or S. aureus, the quinolone susceptible strain was more susceptible to CCCP than the quinolone resistant ones, especially when the incubation with CCCP was extended. Decrease of the intracellular quinolone concentration resulted in a false result-no or weak efflux system in the quinolone susceptible strains. Results suggested that the concentration of CCCP should be optimized in order to detect the efflux system in the quinolone susceptible strains of E. coli.

• 한국지반환경공학회 논문집
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• 제11권12호
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• pp.27-35
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• 2010

지하공간에 설치되는 구조물 중 지하수위 아래에 위치하는 부분은 상향으로 정수압인 부력이 작용하게 된다. 최근 큰 규모의 중요구조물 즉, 부력이 크게 발생하는 구조물은 공사비가 고가이나 안전율을 확실하게 증가시키는 방법인 부력저항 영구앵커를 많이 적용하고 있는 실정이다. 그러나, 부력저항 영구앵커의 저항 메커니즘 규명은 미흡한 실정이다. 특히, 시공 후 앵커의 장기거동에 대한 규명은 계측 관리의 어려움으로 이루어지지 않고 있는 것이 현실이다. 본 연구에서는 부력 저항 영구앵커의 설계 시 합리적인 구조물 거동 평가를 위하여 앵커두부에 하중계를 설치하여 앵커축력을 자동화계측 및 수동계측을 통해 시공초기부터 10년간 계측 분석하였으며, 이를 토대로 건물의 자중증가에 따른 앵커의 시공단계별 거동과 시간 경과에 따른 앵커의 장기거동(시공 후 10년 이내의 거동)을 분석하였다.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2006년도 춘계 학술대회 개요집
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• pp.13-15
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• 2006

The effects of plasma treatment on the surfaces of the FR-4 (Flame Resistant-4) and copper substrates are investigated in terms of X-ray photoelectron spectroscopy (XPS), contact angle, and atomic force microscopy (AFM). The adhesion strengths of the underfills/FR-4 substrate and underfills/copper substrate are also studied. As experimental results, the plasma treatments of FR-4 and copper substrate surfaces yield several oxygen complexes in hydrophilic surfaces, which can play an important role in increasing the surface polarity, wettability, and adhesion characteristics of the underfills/substrates.

• 대한치과교정학회지
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• 제18권2호
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• pp.475-488
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• 1988

Certain malocclusion are associated with specific "facial type," and it is important for the clinician to classify the common facial characteristic of each patient. Because the reaction to treatment mechanics and the stability of the denture is depended upon the analysis of the facial pattern. Basically, there are 3 district facial types or patterns under which almost all malocclusion can be classified. 1. mesofacial is the most average growth. 2. brachyfacial which is a horizontal growth pattern has a week muscle, with dental arch, deep bite. 3. dolichofacial which is a vertical growth pattern has a strong muscle, narrow dental arch, open bite. Brachyfacial pattern show a resistant to mandibular rotation during treatment can accept a more protrusive denture and are prominantly nonextraction, whereas dolichofacial patterns tend to open during treatment require a more retracted denture in order to assure post-treatment stability. Brachyfacial pattern would better treat to use extrusive force system, whereas dolichofacial pattern treat to use intrusive force system with head gear and intermaxillary elastics.

• Wind and Structures
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• 제10권4호
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• pp.383-398
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• 2007

The paper describes a study of the effects of structural coupling on the wind-induced response of twin tall buildings connected by a skybridge. Development of a dual high-frequency force balance used in wind tunnel investigation and background information on the methodology employed in analysis are presented. Comparisons of the wind-induced building response (rooftop acceleration) of structurally coupled and uncoupled twin buildings are provided and the influence of structural coupling is assessed. It is found that the adverse aerodynamic interference effects caused by close proximity of the buildings can be significantly reduced by the coupling. Neglecting of such interactions may lead to excessively conservative estimates of the wind-induced response of the buildings. The presented findings suggest that structural coupling should be included in wind-resistant design of twin tall buildings.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2001년도 춘계학술발표대회 논문집
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• pp.69-73
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• 2001

Damage induced by low-velocity impact on the curved composite laminates was experimentally evaluated for CFRP cylindrical shells with the radius of curvatures of 50, 150, 300, and 500 mm. The result was then compared with that of flat laminates. The radius of curvatures and the effective shell stiffness appeared to considerably affect the dynamic impact response of curved shells. Under the same impact energy level, the maximum contact force increased with the decreasing radius of curvatures, with reaching 1.5 times that for plates at the radius of curvature of 50 mm. Since the maximum contact force is directly related to the impact damage, curved laminates can be more susceptible to delamination and less resistant to the low-velocity impact damage. The distribution of delamination along the thickness direction of curved laminates are also different from that of flat plates. Delamination was distributed rather even]y at each interface along the thickness direction of curved laminates. This implies that the effect of curvatures has to be considered for the design of a curved composite laminate.

• 도시과학
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• 제7권1호
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• pp.5-9
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• 2018

The nickel-titanium shape memory alloy (SMA), referred to as Nitinol, exhibits a superelastic effect that can be restored to its original shape even if a significant amount of deformation is applied at room temperature, without any additional heat treatment after removal of the load. Owing to these unique material characteristics, it has widely used as displacement control devices for seismic retrofitting in civil engineering fields as well as medical, electrical, electronic and mechanical fields. Contrary to ordinarty carbon steel, superelastic SMAs are very resistant to fatigue, and have force-displacement properties depending on loading speed. The change for the mechanical properties of superelastic SMAs are experimentally inviestigated in this study when loading cycle numbers and loading speeds are different. In addition, the standardized force-displacement properties of such superelastic SMAs are proposed with an aim to efficiently design the seismic retrofitting devices made of these materials.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1993년도 가을 학술발표회 논문집
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• pp.267-272
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• 1993

Currently about 60 contries in the world require earthquake resistant structural design in case of multistory building constructions. In these cases the equivalent lateral force procedure is commonly adopted because of its simplicity and convenience. This procedure, however, is developed based mainly on the first vibration mode response of building structure. The dynamic analysis of tall building shows that the effect of higher modes of vibration on the response of the building can not be neglected. In this paper, the effect of higher modes of vibration on seismic response is evaluated through modal analysis of tall building structures. On the basis of evaluation results, an improved procedure is to be proposed for the extended application of the equivalent lateral force procedure.

• Earthquakes and Structures
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• 제7권6호
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• pp.1045-1060
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• 2014

The 2011 off the Pacific coast of Tohoku Earthquake brought serious damage around the Tohoku district in Japan, and much human life and fortune were lost. Bridges were damaged by this earthquake. It was the most serious damage that the superstructures of bridges were flowed out by tsunami. Earthquakes of the same scale are predicted in other areas of Japan. It is necessary to take measures for bridges near coast. In order to understand the tsunami force acting on the bridge, hydraulic model experiments was conducted. In addition, this paper focused on fairing that is effective in wind resistant stability. Installing fairing to bridges has been verified by experiments whether it is possible to reduce the force of tsunami.

• 전산구조공학
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• 제3권4호
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• pp.123-132
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• 1990

일반적으로 구조물의 내진설계에 있어서는 등가정적해석법이 주로 사용되고 있다. 현재 사용되고 있는 등가정적해석법은 구조물의 거동이 주로 기본진동 모드에 의해 지배된다는 가정하에 유도되었으므로 기본진동 주기가 긴 구조물에 대해서는 구조물의 동적특성을 정확하게 예측하기가 어렵다. 본 연구에서는 구조물의 설계시 직접적인 영향을 미치게 되는 층전단력의 분포를 주요 관점으로하여 구조물의 동적특성에 미치는 고차모드의 영향을 정확히 고려할 수 있는 층지진하중에 대하여 연구했다. 층지진하중의 분포를 개선하기 위해 현행 내진설계 기준의 등가정적해석법에서 쓰이는 층지진하중과 모드해석을 이용하여 얻은 층지진하중의 차이를 파악하고 이로부터 고차모드의 영향이 고려된 층지진하중의 분포를 제안했다.