• 한국응용과학기술학회지
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• 제36권3호
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• pp.876-884
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• 2019

We investigated the effect of moderate- and high-intensity resistance training on hippocampal neurotrophic factors and peripheral CCL11 levels in high-fat diet (HFD)-induced obese mice. C57/black male mice received a 4 weeks diet of normal (control, CON; n = 9) or a high-fat diet (HF; n = 27) to induce obesity. Thereafter, the HF group was subdivided equally into the HF, HF + moderate-intensity exercise (HFME), and HF + high-intensity exercise (HFHE) groups (n = 9, respectively), and mice were subjected to ladder-climbing exercise for 8 weeks. The hippocampal brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) levels were significantly lower in the HF group than in the CON group (p < 0.05). In addition, in the HFME and HFHE groups were significantly higher than in the HF group (p < 0.05). The peripheral CCL11 levels were significantly higher in the HF group than in the CON group (p < 0.05). In addition, in the HFME and HFHE groups were significantly lower than in the HF group (p < 0.05). However, there was no significant difference according to the exercise intensity among the groups. Collectively, these results suggest that obesity can induce down-regulation of neurotrophic factors and inhibition of neurogenesis. In contrast, regardless of exercise intensity, resistance training may have a positive effect on improving brain function by inducing increased expression of neurotrophic factors.

• 대한임상전기생리학회지
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• 제6권1호
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• pp.31-42
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• 2008

This study performed in order to investigate the effect of isometric resistance exercise for vastus medialis oblique muscle with EMG(electromyography) biofeedback training which are applied to the patello-femoral joint of patients with osteoarthritis on the improve of function. The subjects had no neuromuscular disorders, and they were elder patients with osteoarthritis, 20 women. And the experiment was performed in control group, taping with EMG biofeedback training group respectively, and the measurement was carried out before and after the treatment and 4 weeks after the treatment. Motor unit action potential analysis with surface electromyography showed a significant change in RMS(root mean square) amplitude and MDF(median frequency) in vastus medialis oblique muscle(p<0.05). VMO/VL(vastus medialis oblique/vastus lateralis oblique) MDF ratio showed a significant change between groups(p<0.05). Taping with EMG biofeedback training applied to patello-femoral joint of osteoarthritis patients appeared to be effective for muscle function improvement. However, increase of muscular force in vastus medialis oblique muscle appears to have a positive effect on improve of function along with correction effect on patella malalignment. In conclusion, in case of osteoarthritis patients with loss of patello-femoral joint function, it appears to be effective to practice isometric resistance exercise of vastus medialis oblique muscle selective with taping.

• 대한물리의학회지
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• 제13권3호
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• pp.141-150
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• 2018

PURPOSE: This study was conducted to understand the adaptive responses of different modes of physical exercises utilizing skeletal muscle and the comprehensive relevance of AMPK signaling that can be activated by physical exercise as a potential molecular target in human health problems such as neuromuscular disorders (NMDs). METHODS: Most of the contents in this review article are based on recent publications concerning the main topics of interest. The reference literatures cited were obtained by basic searches of overseas academic databases such as PubMed and ScienceDirect using EndNote X7.8. RESULTS: The phenotypic adaptive responses of skeletal muscle during endurance- and resistance-based exercise training (ET and RT respectively) appear to be distinct. To explain the adaptive responses in each single mode of exercises (ET, RT) along with combined exercise training (CT), AMPK signaling is proposed as an important molecular link among those differential modes of exercise and a promising molecular target of NMDs. CONCLUSION: Based on the available evidence, intracellular AMPK signaling activated by diverse stimuli including physical exercise can be a potential and promising therapeutic target for the prevention, amelioration or cure of various human health problems including NMDs and may also be beneficial for physical rehabilitation and emergency situations that may elicit acute metabolic stresses.

• 한국산림과학회지
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• 제98권6호
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• pp.681-689
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• 2009

8주간 옻나무 추출액을 섭취하며 운동을 병행하였을 때 혈중 지질 성분, 인슐린 저항성에 미치는 영향에 대해 연구하였다. 6주된 SD계 수컷 쥐를 대상으로 CON(대조군), RVS(추출액 섭취군), EXE(운동군), 그리고 RVS-EXE(추출액 섭취와 운동 병행군)로 구분하였다. 각 집단의 체중은 EXE(202%)와 RVS-EXE(203%)가 CON(253%)과 RVS(239%)에 비해 통계적으로 유의하게 낮은 증가를 보였다. 저장지방은 옻나무 추출액 혹은 운동에 의해 유의하게 감소하는 것으로 나타났다. 혈중 지질성분은 RVS와 RVS-EXE에서 CON에 비하여 통계적으로 유의하게 개선되는 것으로 나타났다. 혈중 글루코스는 CON에 비하여 다른 집단에서 유의하게 낮은 것으로 나타났으며, 인슐린 역시 동일하였으나, RVS-EXE에서 유의한 상승작용이 나타났다. HOMA 지수는 인슐린과 동일한 결과를 나타내었다. 이와 같은 결과를 종합해 볼 때 옻나무 추출액 섭취와 함께 운동의 병행은 저장지방을 감소시키고 혈중 지질을 억제하며, 인슐린 저항성을 개선시키므로 대사증후군 즉, 당뇨병, 비만, 고지혈증 등을 효과적으로 억제할 수 있다는 점을 시사한다.

• The Plant Pathology Journal
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• 제38권4호
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• pp.272-286
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• 2022

Black root rot (BRR) caused by Lasiodiplodia theobromae is an alarming disease of mulberry that causes tremendous economic losses to sericulture farmers in India and China. Successful control of this disease can be attained by screening germplasm and identifying resistant sources. Seventy four diseased root samples were collected from farmer's fields belonging to four major mulberry growing states of South India. Based on morpho-cultural and scanning electron microscopy studies, 57 fungal isolates were characterized and identified as L. theobromae. Phylogenetic analysis of concatenated internal transcribed spacer and β-tubulin sequences revealed variation of the representative 20 isolates of L. theobromae. Following the root dip method of inoculation, pathogenicity studies on susceptible mulberry genotypes (Victory-1 and Thailand male) recognized the virulent isolate MRR-142. Accordingly, MRR-142 isolate was used to evaluate resistance on a set of 45 diverse mulberry accessions. In the repeated experiments, the mulberry accession ME-0168 which is an Indonesian origin belonging to Morus latifolia was found to be highly resistant consistently against BRR. Eight accessions (G2, ME-0006, ME-0011, ME-0093, MI-0006, MI-0291, MI-0489, and MI-0501) were found to be resistant. These promising resistant resources may be exploited in mulberry breeding for developing BRR resistant varieties and to develop mapping populations which successively helps in the identification of molecular markers associated with BRR.

• 대한간호학회지
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• 제42권7호
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• pp.947-956
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• 2012

Purpose: To investigate the effect of progressive resistance training (PRT) on body composition, physical fitness, quality of life, lipid and nutritional profile of patients on hemodialysis (HD). Methods: A non equivalent comparison group pretest and posttest design study was used with 40 participants who were randomly assigned to the exercise group (20 participants) and the comparison group (20 participants). The exercise group received PRT for 30 minutes per session, 3 sessions a week, for 12 weeks, while the comparison group received usual care. The PRT consisted of upper and lower body exercises using elastic bands and sandbags. Outcome measures evaluated were: body composition, physical fitness, quality of life, and lipid profile. Results: Skeletal muscle mass, grip, leg muscle strength, and quality of life all improved significantly in the exercise group. Body fat rate, total cholesterol and triglyceride rate decreased significantly in the exercise group. Conclusion: These results suggest that PRT improves body composition, physical fitness, quality of life, and lipid profile of patients on HD. PRT using elastic bands and sandbags can be utilized as part of a regular care plan for these patients.

• Advances in concrete construction
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• 제5권6호
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• pp.587-611
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• 2017

This study focused on the influences regarding the use of polyepoxide-based polymer and silica fume (SF) on the fresh and hardened state properties of self-compacting lightweight concrete (SCLC) along with their impacts on electrical resistance and ultrasonic pulse velocity (UPV). To do so, two series of compositions each of which consists of twelve mixes, with water to binder (W/B) ratios of 0.35 and 0.4 were cast. Three different silica fume/binder ratios of 0, 5%, and 10% were considered along with four different polymer/binder ratios of 0, 5%, 10%, and 15%. Afterwards, the rupture modulus, tensile strength, 14-day, 28-day, and 90-day compressive strength, the UPV and the electrical resistance of the mixes were tested. The results indicated that although the use of polymer could enhance the passing and filling abilities, it could lead to a decrease of segregation resistance. In addition, the interaction of the SF and the polymeric contents enhanced the workability. However, the impacts regarding the use of polymeric contents on fresh state properties of SCLC were more prevalent than those regarding the use of SF. Besides the fresh state properties, the durability and mechanical properties of the mixes were affected due to the use of polymeric and SF contents. In other words, the use of the SF and the polymer enhanced the durability and mechanical properties of SCLC specimens.

• 대한통합의학회지
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• 제6권3호
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• pp.103-112
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• 2018

Purpose : The purpose of this study was to determined the effects of resistance and aerobic exercise on gait ability, physical fitness and body compositions in older women. Method : The subjects were 24 older women who were randomly divided into two groups (resistance exercise, n=12, and aerobic exercise, n=12). They 65~80 years old. The subjects done the Gym-ball, Togu, and senior dance exercise three times per week-for 70 minutes each time for 16 weeks. Body compositions, physical fitness, and gait ability were measured in this study. Result : There were significantly improved the walk performance after exercise training for 16 weeks. In particular, it was more effective on resistance exercise training in older women. There were significant differences in muscle endurance, flexibility, balance, body weight, percent of body fat, and body mass index (BMI) after the exercise program. Conclusion : It was more effective improved on muscle endurance, flexibility, and balance performance after resistance exercise program than an aerobic exercise program in older women.

• The Korean Journal of Physiology and Pharmacology
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• 제19권3호
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• pp.191-196
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• 2015

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

• 대한통합의학회지
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• 제7권4호
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• pp.231-240
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• 2019

Purpose : This study aimed to determine whether resistance exercise using elastic bands for 6 weeks could improve the muscle strength, muscle tone, balance and gait among stroke patients. Methods : A total of 11 stroke patients who had agreed to participate in the study were randomly divided into 3 groups receiving elastic band resistance training on their less affected side (experimental group 1, n=4), affected side (experimental group 2, n=3), and both the sides (experimental group 3, n=4). Muscle strength, muscle tone, balance and gait were assessed using a hand-held dynamometer, the modified ashworth scale (MAS), the berg balance scale (BBS), and G-walk respectively, before and after training. Wilcoxon signed-rank test was used to analyze intergroup changes after the intervention, whereas the Kruskal Wallis H test, and Mann-Whitney U test were used to analyze intergroup changes in all variables. Results : Strength in all the muscle, except for the flexor and extensor muscles in the affected knees, was increased in all the groups, however, no significant difference was observed. No change in the muscle tone (MAS) was found in any group. All the groups showed increased BBS scores walking speed, and walking symmetry following training, although, the differences were not significant. Changes in the affected step length of experimental group 1 were significantly greater than those of experimental group 3, whereas changes in the affected step length in experimental group 3 were significantly greater than those of experimental group 2. Conclusion : Our results suggest that resistance exercise using elastic bands are a potential intervention for improving lower extremity muscle strength, balance, and gait among stoke patients.