• Title/Summary/Keyword: Residual resistance

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Effect of Metal Ions and Substrate on the Thermostability of ${\alpha}-Amylase$ from Bacillus licheniformis (Bacillus licheniformis가 생산하는 ${\alpha}-Amylase$의 열안정성에 미치는 금속이온 및 기질의 영향)

  • Yoon, Jong-Won;Park, Kwan-Hwa
    • Korean Journal of Food Science and Technology
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    • v.24 no.4
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    • pp.371-375
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    • 1992
  • The ${\alpha}-amylase$ from Bacillus licheniformis was purified and its thermostability in the presence of substrate and metal was ions investigated. Comparing D-values of the enzyme obtained in the presence of $Ca^{++}$, $B^{+++}$ and both $Ca^{++}$ and $B^{+++}$, the thermostability of the enzyme was markedly enhanced by the addition of metal ions. $Ca^{++}$ and $B^{+++}$ exhibited a protective action, the former ion being more effective, and both ions showed a synergistic effect. The enthalpy of activation for the thermal inactivation in the presence of metal ion was 320.2 kJ/mole for $Ca^{2+}$ ion, 212.9 kJ/mole for $B^{+++}$, while it was 183.9 kJ/mole in the absence of metal ions. In the thermal inactivation for 30 min at $96^{\circ}C$, the residual activity in the presence of 30% (w/w) starch was 51.0%, whereas the presence of $Ca^{++}$ ion additionally provided a remarkable thermo-resistance.

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Reliability Analysis of Caisson Type Quaywall (안벽구조물의 신뢰성 해석)

  • Yoon, Gil-Lim;Kim, Dong-Hywan;Kim, Hong-Yeon
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.20 no.5
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    • pp.498-509
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    • 2008
  • Reliability analyses of Level I, II and III for bearing capacity, overturning and sliding of quaywall are carried out to investigate their safety levels depending upon its failure modes, and sensitivity analyses of each design variable are performed to find their effects on safety levels of quaywall. Reliability indices was 1.416 for both level II and III for case study I, and with 2.201 and 1.880, respectively, for the case study II at the critical loading conditions. Thus we were able to know that Level II (FORM) approach is good enough to use in practical design. Generally, it was found that probabilities of failure of quaywall were higher for sliding and bearing capacity failure modes and lower for overturning failure mode. From sensitivity analyses, the most influential design variables to reliability index of quaywall were coefficient of friction, residual water pressure and resistance moment for the sliding, overturning and bearing capacity failure modes, respectively. Especially, the sensitivity of reliability index due to inertial force and dynamic water pressures, which include a large COV when earthquake occurs, did not change greatly.

Genetic Relationship of Productive Life, Production and Type Traits of Korean Holsteins at Early Lactations

  • Wasana, Nidarshani;Cho, GwangHyun;Park, SuBong;Kim, SiDong;Choi, JaeGwan;Park, ByungHo;Park, ChanHyuk;Do, ChangHee
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.9
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    • pp.1259-1265
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    • 2015
  • The present study was performed to study the genetic relationship of productive life with production and type traits of Korean Holsteins at first three lactations. The data for the analysis from 56,054, 28,997, and 11,816 animals of first, second and third parity cows which were born from 2006 to 2011 were collected by Dairy Cattle Improvement Center, National Agricultural Co-operative Federation. Milk, protein and fat yields adjusted for 305 days and average somatic cell score considered as production traits and analyzed type traits were stature, strength, body depth, dairy form, rump angle, rump width, rear leg side view, foot angle, front attachment placement, rear attachment height, rear attachment width, udder cleft, udder depth, front teat placement and front teat length. A multi trait genetic analysis was performed using Wombat program with restricted maximum likelihood animal model composed of fixed effect of birth year, farm and the random effect of animal and random residual effect according to the traits. Heritability estimates of productive life were between 0.06 and 0.13. Genetic and phenotypic correlations between production and productive life traits ranged from 0.35 to 0.04 for milk, 0.16 to 0.05 for protein and 0.18 to 0.02 f 15-0034 (2nd) 150520 or fat. Somatic cells score showed a negative genetic and phenotypic correlation with productive life and also udder type traits, indicating that the selection for higher udder traits will likely to improve resistance to mastitis and persistence in the herd. Among all dairy form type traits, udder characters such as udder cleft showed a significant relationship with productive life. However, a specific change of heritabilities or correlations were not observed with the change of parity. Moreover, further studies are needed to further confirm the significance of the above traits and the effect of parity on above relationships in order to minimize both voluntary and involuntary culling rates while improving herd health and maintaining high yielding dairy cows.

Development and Uncertainty Assessment of Interface Friction Prediction Equation Between Steel Surface and Cohesionless Soils (강재면과 사질토 사이의 경계면 마찰각 예측식 개발 및 불확실성 평가)

  • Lee, Kicheol;Kim, So-Yeun;Kim, Dongwook
    • Journal of the Korean Geosynthetics Society
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    • v.17 no.2
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    • pp.33-40
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    • 2018
  • Characteristics of interface friction between cohesionless soils and geotechnical structure surfaces play an important role in the analysis of earth load and resistance on the structure. In general, geotechnical structures are mainly composed of either steel or concrete, and their surface roughnesses with respect to soil particle sizes influence the interface characteristics between soils and the structures. Accurate assessment of the interface friction characteristics between soils and structures is important to ensure the safety of geotechnical structures, such as mechanically stabilized earth walls reinforced with inextensible reinforcements, piles embedded into soils, retaining wall backfilled with soils. In this study, based on the database of high quality interface friction tests between frictional soils and solid surfaces from literature, equation representing peak interface friction angle is proposed. The influential factors of the peak interface friction angle are relative roughness between soil and solid surface, relative density of frictional soil, and residual (constant volume) interface friction angle. Futhermore, for the developed equation of the interface friction angle, its uncertainty was assessed statistically based on Goodness-of-fit test results.

INFLUENCE OF COOLING RATE ON THERMAL EXPANSION BEHAVIOR AND FLEXURAL FAILURE OF PFM SYSTEMS (도재 냉각방법의 차이가 금속-도재간 열팽창 양상과 결합력에 미치는 영향)

  • Lim, Ae-Ran;Lim, Ho-Nam;Park, Nam-Soo
    • The Journal of Korean Academy of Prosthodontics
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    • v.28 no.1
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    • pp.165-191
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    • 1990
  • Although a number of studies have been performed to assure that residual stress caused by a mismatch of alloy porcelain thermal expansion can contribute to clinical failure of a ceramometal restoration, the interactive influence of cooling rate on the magnitude of thermal expansion difference and on bond strength between them have not been extensively analyzed. The objective of this study was to determine the influence of cooling rate and the number of firing cycles on the expansion mismatch and the flexural failure resistance of metal porcelain strip. Tested alloys included one Pd-Ag alloy, one Ni-Cr-Be alloy with two kinds of porcelain, Vita and Ceramco. Metal specimens were cast into rods with a height of 13mm and a diameter of 5mm. Subsequently, the castings were subjected to scheduled firing cycles without porcelain. And the porcelain specimens after being fired were trimmed into a bar with a final dimension of $5{\times}5{\times}25mm$. Thermal expansions of the alloys and porcelains were measured by using a push rod or a differential dialometer respecitvely. Porcelain glass transition temperatures and expansion values were derived alloy-porcelain pairs were assessed by comparing expansion values of the components at a porcelain glass transition temperature. Calculations were made using combinations of a Ni-Cr alloy or Pd-Ag alloy with each of two porcelain products. Metal-porcelain strip specimens were subjected to four point loading in an Instron testing machine until crack occured at the metal-cramic interface at the time of sharp decrease of load on recorder. On the basis of this study, the following conclusions may be stated: 1. Regardless of the kinds of ceramometal combinations, both of calculated and experimental data revealed that the double fired specimens exhibited a significantly lower flexural strength. 2. By the rise of the amount of mismatch, bond strength were decreased. 3. Thermal expansion value of Pd-Ag alloys were higher than that of Ni-Cr alloys. 4. Expansion curves of metal were proportional to the increase of temperature and were not affected by the experimental conditions, however porcelains did not show the same magnitude of metal, and a shift of the glass transition temperature to higher temperatures was observed when cooled rapidly 5. Alloy-porcelain thermal compatibility appeared more dependent on the porcelain than the alloy.

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Scientific Feasibility on the Risk-Based Clean-up and Management of Contaminated Sites ("위해성" 개념을 이용한 오염지역 정화 및 관리의 과학적 타당성)

  • Shin, Won-Sik
    • Journal of Soil and Groundwater Environment
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    • v.12 no.1
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    • pp.1-35
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    • 2007
  • In the last decades, the decrease in biological or chemical availability of sorbed contaminants as contact time passed, is generally accepted. This phenomenon so called as "aging" or "sequestration" is known to directly affect risk of the contaminats. This was observed for mainly for hydrophobic organic contaminants (HOCs), but also reported for heavy metals. Aging is known to be directly related to sorption-desorption hysteresis, irreversible sorption, desorption-resistance, nonequilibrium sorption, etc. The decrease in bioavailability due to aging or sequestration indicates realistic decrease in risk potential. Recently a risk-based management concept by scientific evidences but not the simple measurement of contaminant concentration has been attempted to determine environmentally acceptable remedial endpoint. This is because selection of remedial endpoint based on not total concentration but the bioavailability and toxicity of contaminants can reduce both the treatment cost and remedial activities of the contaminated sites. The bioavailability and toxicity of the residual contaminants are highly affected by the fate and transport and also directly affect the exposure pathways and bioaccumulation of contaminants in the living biota. In this paper, scientific feasibility on the risk-based clean-up and management of contaminated sites is reviewed.

Comparative Inactivation of Hepatitis A Virus and Murine Encephalomyocarditis Virus to Various Inactivation Processes (바이러스 불활화 공정에 대한 Hepatitis A Virus와 Murine Encephalomyocarditis Virus의 민감도 비교)

  • Kim, In-Seop
    • Korean Journal of Microbiology
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    • v.39 no.4
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    • pp.242-247
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    • 2003
  • Murine encephalomyocarditis virus (EMCV) has been used as a surrogate for hepatitis A virus (HAV) for the validation of virus removal and/or inactivation during the manufacturing process of biopharmaceuticals. Recently international regulation for the validation of HAV safety has been reinforced because of the reported cases of HAV transmission to hemophiliac patients who had received ntihemophilic factors prepared from human plasma. The purpose of the present study was to compare the resistance of HAV and EMCV to various viral inactivation processes and then to standardize the HAV validation method. HAV was more resistant than EMCV to pasteurization (60oC heat treatment for 10 hr), low pH incubation (pH 3.9 at 25oC for 14 days), 0.1 M NaOH treatment, and lyophilization. EMCV was completely inactivated to undetectable levels within 2 hr of pasteurization, however, HAV was completely inactivated to undetectable levels after 5 hr treatment. EMCV was completely inactivated to undetectable levels within 15 min of 0.1 M NaOH treatment, however, residual infectivity of HAV still remained even after 120 min of treatment. The log reduction factors achieved during low pH incubation were 1.63 for HAV and 3.84 for EMCV. Also the log reduction factors achieved during a lyophilization process of antihemophilic factor VIII were 1.21 for HAV and 4.57 for EMCV. These results indicate that HAV rather than EMCV should be used for the virus validation study and the validation results obtained using EMCV should be precisely reviewed.

Effect of Processing Factors on the Properties of Melt-blown PP/Ba-ferrite Composite Fabrics (Melt-blown 방사에 의한 PP/Ba-ferrite 복합 부직포 제조시의 공정인자가 부직포의 특성에 미치는 영향)

  • Han, Jong-Hun;Lee, Dong-Jin;Lim, Hyung Mi;Lee, Seung-Ho;Oh, Sung Geoun
    • Applied Chemistry for Engineering
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    • v.17 no.3
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    • pp.267-273
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    • 2006
  • We have prepared PP/Ba-ferrite composite fabrics by a melt-blown spinning method and investigated the relationship between the properties of PP/Ba-ferrite composite fabrics and melt-blown processing factors. A PP composite containing Ba-ferrite as a magnetic particulate filler was prepared in the form of pellet from PP resin and Ba-ferrite powder by melt compounding using a single extruder. Screw turning force (rpm), DCD (die-to-collector distance), and Ba-ferrite content were changed. We measured diameters of fiber, mechanical, thermal, and magnetic properties for the composited PP fabrics. The elongation was increased and a fiber diameter and tensile strength were decreased as the spinning distance increased or screw turning force decreased. The crystallinity was increased with increasing spinning distance according to XRD. It was assumed that the orientation of crystalline domain in the neat PP without ferrite was increased by drawing in mechanical direction, however, the orientation in the PP composite was decreased according to XRD analysis. We measured a magnetic property of PP nonwoven fabric containing Ba-ferrite powder. A coercive force, maximum magnetization, and residual magnetization are reduced with the spinning distance. According to the result of TGA measurement, the heat resistance was increased with the Ba-ferrite powder content and with decreasing the spinning distance.

AN EXPERIMENTAL STUDY OF EFFECT OF INTERMAXILLARY FIXATION AND OCCUSAL SPLINT ON PULMONARY FUNCTION (악간고정과 교합 상이 호흡기능에 미치는 영향에 관한 실험적 연구)

  • Lee, Joong-Kyou;Kim, Kyung-Wook;Lee, Jae-Hoon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.3
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    • pp.175-181
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    • 2002
  • Intermaxillary fixation and occusal splint are routine procedure for maxillofacial fracture and orthognathic surgery. When these methods could obstruct oral airway the patients who kept intermaxillary fixation and occusal splint in their mouth, are very difficult to breath after surgery. Nasal bleeding and pharyngeal edema due to nasotracheal intubation, residual effect of muscle relaxants, and anesthetic agent could be contributing factor of airway obstruction. In this study, pulmonary function test was evaluated before and after intermaxillary fixation, and intermaxillary fixation with occusal splint in 22 volunteers. The results were as follows 1. FVC, %FVC, $FEV_1$, $FEV_1%$, PEF, $PEF_{50}$, MVV without intermaxillary fixtion were 4.45L, 88%, 4.03L, 90.9%, 10.26L/s, 5.53L/s, and 136.14L/min, and with intermaxillary fixation were 3.51L, 68.67%, 3.06L, 69.39L, 6.52L/s, 3.94L/s, and 69.39L/min. The results with intermaxillary fixation and occusal splint were 2.15L, 42.41%, 1.71L, 38.81%, 2.83L/s, 1.74L/s, and 37.14L/min. 2. Compared with before and after intermaxillary fixation, all values of pulmonary function test were decreased and after intermaxillary fixation and intermaixillary fixation with occulasal splint, the results were decreased. 3. MVV and PEF were decreased significantly with interaxillary fixtion and occusal splint, and FVC was less decreased. It meant that intermaxillary fixation and occluasal splint induced reduction of respiratory flow significantly, but less reduction of respiratory volume. 4. Intermaxillary fixation and occulsal splint induced increase of airway resistance, decrease of expiratory volume and air flow. So severe respiratory difficulty could be seen to all volunteers who kept intermaxillary fixtion and occusal splint. 5. In classification of respiratory difficulty, intermaxillary fixation with occulsal splint induced complex respiratory difficulty more than intermaxillary fixation only did. From the above results, doctors who care patients kept intermaxillary fixation and occusal splint should be aware of respiratory depression caused by these treatment.

An Investigation of the Control of Two-Spotted Spider Mites (Tetranychus urticae Koch) Resistant to Organo-Phosphates (유기인제저항성 점박이응애(Tetranychus urticae Koch)에 관한 연구)

  • Lee Seung Chan;Harrison R. A.
    • Korean journal of applied entomology
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    • v.7
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    • pp.39-51
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    • 1969
  • The study involved determination of resistance levels of spider mites ta argano-phosphates using topical application and slide dip techniques; laboratory serening tests of alternative acaricides using an O/P resistant strain and a field trial of the screened materials. 1. Strains of Tetranychus were from Timaru(TR), Havelock Narth (HNR), Lincaln (LN). Germany (GR, GN). Comparisons of the resistant strains and normal strains at the LD50 and LC50 levels were as follows : (a) Using the topical application tochnique; with Parathian. resistant levels of the GR. TR and HNR strains of T. urticae were respeativuly, 1035. 484 and 452 times as resistant' as the LN strain. (b) Using the slide dip technique; with Phosdrin, resistant of GR, TR and HNR strains of T. urticae were 635, 274 and 266 times greater respeativuly, than the GN strain. 2. The laboratory sereaning tests were carried out far their contact plus stomach and residual effect to assess the toxicities of eleven alternative materials which would be used far control of O/P resistant strain of T. urticae. The acaricide groups represented were 3 organo-chlorines (Spidex, Kelthane and C 8514), 2 nitrophenyls (UC 19786 and Morocide), 2 cyclic carbonates(Eradex and Morestan). I carbamate (UC2004 7A), 1 mixture of carbamate and orano-chlorine and 2 other chemicals (C 8677 and M2527). From all acaricide tested. Kelthane and Morocide were the most effective, folowed by Spidex and M2527. Morestan, C8514. C8677 and RS 143 were intermediate, but Eradex, UC 19786 and UC 20046A were poor. 3, The number of sapmles required for estimation of the population in the field evaluation of acaricidal effects was one giving the highest practical precision. It was decided, after preliminary sampling trials. to use samples of 30 leaves per replicate which gave a $5.7\%$ standard error. 4. In the field trials, Morocide applied at the $0.05\%\;and\; 0.04\%$ a. i. conc. to black currant trees gave excellent control of O/P resistant population of T. urticae for about 12 days, but Morocide 0.025 and Kel thane $0.02\%$ a. i. cone. gave efficient control for about 6 days. In other words. first applications of Kel thane ane Moroeide gave very high degrees of control of O/P resistant population of the two-spotted spider mite. However, the results indicate that secondary application would sometimes be necessary. There was no foliage damage of black Currants and strawberries by either acaricides at the concentrations used. Acknowledgment ... The authors are grateful to: Dr. R. P. pottinger, Senior Lecturer in Agricultural Zoology. Lincoln college. New Zealand. for his helpful assistance in aiding with the organization of thd field work. Department of agriculture officers for mite colonies. Mr. D. A. Slade, Technical Advisor. Fruitgrowers' Federation (now at Massey University) for his assistance and provision of mites for testing. Mr T. McRae of Timaru for permission to use his crops for field tests. The following chemical companies and I or their New Zealand agents for so readily supplying samples of acarides; Ivan Watkins-Dow Limited. Fruitgrowers Chemical Company Limited. Henry H. York & company (New Zealand). Shell Oil (New Zealand) Limited.

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