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Maturation Conditions Affecting on Blastocysts Development and Their Quality in Pig Embryos

  • Kim, Ji-Su;Koo, Deog-Bon;Song, Bong-Suk;Gabbine Wee;Choo, Young-Kug;Lee, Kyung-Kwang;Han, Yong-Mahn
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2004년도 춘계학술발표대회
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    • pp.240-240
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    • 2004
  • The modification of in vitro maturation (IVM) conditions should be required to efficient production of matured porcine oocyte in vitro. Estradiol-17β (E₂) as steroid hormone exists in ovarian follicular fluid and plays a major role in ovulation. It has been reported that estradiol as well as other steroids are involved in keeping the oocytes in meiotic arrest. (omitted)

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Attenuation of Morphine Tolerance and Withdrawal Syndrome by Coadministration of Nalbuphine

  • Jang, So-Yong;Kim, Hee-Jeong;Kim, Dong-Hyun;Jeong, Myeon-Woo;Ma, Tangen;Kim, Seong-Youl;Ho, Ing K.;Oh, Sei-Kwan
    • Archives of Pharmacal Research
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    • 제29권8호
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    • pp.677-684
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    • 2006
  • Morphine has been used widely on the treatment of many types of chronic pain. However the development of tolerance to and dependence on morphine by repeat application is a major problem in pain therapy. The purpose of the present study was to investigate whether combined administration of nalbuphine with morphine affects the development of tolerance to and dependence on morphine. We hypothesize that the use of nalbuphine, ${\kappa}-agonist$ may prove to be useful adjunct therapy to prevent morphine-induced undesirable effects in the management of some forms of chronic pain. Morphine (10 mg/kg) was injected to rats intraperitoneally for 5 day. The variable dose of nalbuphine (0.1, 1.0 and 5.0 mg/kg) was administered (i.p.) in combination with morphine injection. The development of morphine tolerance was assessed by measuring the antinociceptive effect with the Randall-Selitto apparatus. The development of dependence on morphine was determined by the scoring the precipitated withdrawal signs for 30 min after injection of naloxone (10 mg/kg, i.p.). Nalbuphine did not attenuate antinociceptive effect of morphine in rats. Interestingly, combined administration of morphine with nalbuphine (10:1) significantly attenuated the development of dependence on morphine. The elevation of $[^3H]MK-801$ binding in frontal cortex, dentate gyrus, and cerebellum after chronic morphine infusion was suppressed by the coadministration of nalbuphine. In addition, the elevation of NR1 expression by morphine was decreased by the coadministration of nalbuphine in rat cortex. These results suggest that the coadministration of nalbuphine with morphine in chronic pain treatment can be one of therapies to reduce the development of tolerance to and dependence on morphine.

A comparative analysis of characteristics and antioxidant capacity of Korean mulberries for efficient seedling cultivation

  • Chan Young Jeong;Heon Woong Kim;Seong Ryul Kim;Hyun-Bok Kim;Kee-Young Kim;Seong-Wan Kim;Jong Woo Park;Ik Seob Cha;Sang Kug Kang;Ji Hae Lee
    • International Journal of Industrial Entomology and Biomaterials
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    • 제47권2호
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    • pp.147-154
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    • 2023
  • Mulberry exhibits unique characteristics and functionalities across various components, including the roots, branches, leaves, and fruits. However, despite numerous studies on mulberry, research on this plant at the seedling stage is insufficient. Therefore, this study aimed to compare the suitability for seedling cultivation and antioxidant effects of four Korean mulberry cultivars, namely, Daesim, Suhong, Simgang, and Cheongsu. In terms of seed weight, germination rate, and growth rate, Daesim was the most suitable cultivar for seedling production. Polyphenol and flavonoid content analysis showed that all cultivars, except for Cheongsu, showed the highest phenolic content at the 2-week seedling stage. Similarly, antioxidant assays using 2,2'-azino-di-3-ethylbenzthiazoline sulfonic acid (ABTS) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radicals revealed that the antioxidant effect of all cultivars, except for Cheongsu, increased with cultivation at 2- 4- and 6-week. However, mulberry seedlings had a slower reaction rate against DPPH radical removal than mulberry leaves. In addition, ABTS radical scavenging activity showed a different correlation with polyphenol content. This phenomenon may be due to the different polyphenol compositions between mulberry leaves and seedlings. The results of this study suggest that mulberry seedlings exhibit different bioactivities from mulberry leaves, and component analysis is required in further research.

Current Research, Industrialization Status, and Future Perspective of Cultured Meat

  • Seung Hyeon Yun;Da Young Lee;Juhyun Lee;Ermie Mariano Jr;Yeongwoo Choi;Jinmo Park;Dahee Han;Jin Soo Kim;Sun Jin Hur
    • 한국축산식품학회지
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    • 제44권2호
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    • pp.326-355
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    • 2024
  • Expectations for the industrialization of cultured meat are growing due to the increasing support from various sectors, such as the food industry, animal welfare organizations, and consumers, particularly vegetarians, but the progress of industrialization is slower than initially reported. This review analyzes the main issues concerning the industrialization of cultured meat, examines research and media reports on the development of cultured meat to date, and presents the current technology, industrialization level, and prospects for cultured meat. Currently, over 30 countries have companies industrializing cultured meat, and around 200 companies that are developing or industrializing cultured meat have been surveyed globally. By country, the United States has over 50 companies, accounting for more than 20% of the total. Acquiring animal cells, developing cell lines, improving cell proliferation, improving the efficiency of cell differentiation and muscle production, or developing cell culture media, including serum-free media, are the major research themes related to the development of cultured meat. In contrast, the development of devices, such as bioreactors, which are crucial in enabling large-scale production, is relatively understudied, and few of the many companies invested in the development of cultured meat have presented products for sale other than prototypes. In addition, because most information on key technologies is not publicly available, it is not possible to determine the level of technology in the companies, and it is surmised that the technology of cultured meat-related startups is not high. Therefore, further research and development are needed to promote the full-scale industrialization of cultured meat.

Effects of Different Nitrogen Application Levels on Yield and Protein Content of Rice Varieties in Korea

  • Jinseok Lee;Jong-Seo Choi;Shingu Kang;Dae-Woo Lee;Woonho Yang;Seuk-Ki Lee;Su-Hyeon Sin;Min-Tae Kim
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.123-123
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    • 2022
  • In order to evaluate the effect of nitrogen application levels on yield and protein content of rice varieties, a field experiment was conducted at National Institute of Crop Science of Korea in 2020. Five levels(0, 3, 5, 7, and 9 kg·10a-1) of nitrogen fertilizer were treated to six Korean rice varieties. The nitrogen uptake amount, soil nitrogen content before and after rice cultivation, milled rice yield, and protein content in head rice were analyzed. As the treatment of nitrogen fertilizer increased, the nitrogen uptake amount of plants increased significantly. However, changes in nitrogen content in the soil before and after rice cultivation were different for each cultivar. The amount of nitrogen change in the soil decreased as the amount of nitrogen application increased in the three cultivars of Haepum, Gopum, and Odae, and the other three cultivars showed the opposite trend. As a result of correlation analysis of nitrogen application amount, nitrogen uptake amount, milled rice yield, and protein content of head rice, the five varieties except for Haepum showed a high correlation between these factors. The amount of nitrogen application and nitrogen uptake of plant showed a positive correlation about the milled rice yield and protein content of head rice. In particular, the protein content in head rice appeared to be more affected by nitrogen uptake amount than nitrogen application amount. As a result of this study, the yield and protein content of rice had positive correlations with the level of nitrogen fertilizer, and had a high correlation with the nitrogen absorption of plants.

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넙치 혈액중의 TBT 축적과 환경모니터링의 응용 (Accumulation of Tributyltin in Blood of Olive Flounder, Paralichthys olivaceous, and its application for Monitoring in Marine Environment)

  • Shim, Won-Joon;Jeon, Jung-Kyun;Oh, Jae-Ryoung;Kim, Nam-Sook;Lee, Soo-Hyung
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2001년도 추계심포지움 및 학술발표회:환경오염의 생체지표를 이용한 위해성 평가의 최근 기법
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    • pp.77-77
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    • 2001
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Research and Development of High Performance 50-inch HD Plasma Display Panel

  • Choi, Kwang-Yeol;Min, Woong-Kee;Rhee, Byung-Joon;Ahn, Byung-Nam;Kim, Je-Seok;Moon, Won-Seok;Park, Min-Soo;Ryu, Byung-Gil;Kim, Sung-Tae;Ahn, Young-Joon;Yang, Sung-Soo;Kim, Kyung-Tae;Lee, Kyu-Sung
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.1547-1550
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    • 2008
  • We are suggesting a new index to represent the performance of PDP, such as Specific Performance Index (SPI) that includes luminous efficacy and panel reflectance. High Xe gas mixture and low panel capacitance are well known as key factors to improve luminous efficacy of PDP [1]. However, higher driving voltage and longer discharge time lag is an obstacle when applying these technologies. Modified cell design, new materials and driving waveform enable us to overcome these obstacles. High efficient phosphor is also a key material to improve luminous efficacy. Phosphors coated with pigment are used to reduce panel reflectance. High performance 50-inch HD PDP with luminous efficacy of 2.3 lm/W has been developed.

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