• Title/Summary/Keyword: Research Information Systems

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Nanoparticle Induced Oxidative Stress in Cancer Cells: Adding New Pieces to an Incomplete Jigsaw Puzzle

  • Nogueira, Daniele Rubert;Rolim, Clarice M. Bueno;Farooqi, Ammad Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.4739-4743
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    • 2014
  • Nanotechnology is an emerging field with many promising applications in drug delivery systems. Because of outstanding developments in this field, rapidly increasing research is directed to the development of nanocarriers that may enhance the availability of drugs to the target sites. Substantial fraction of information has been added into the existing scientific literature focusing on the fact that nanoparticles usually generate reactive oxygen species to a greater extent than micro-sized particles. It is worth mentioning that oxidative stress regulates an array of cell signaling cascades that resulted in cancer cell damage. Accumulating experimental evidence over the years has shown that wide-ranging biological mechanisms are triggered by these NPs in cultured cells due to the unique properties of engineered nanoparticles. In this review, we have attempted to provide an overview of the signaling cascades that are activated by oxidative stress in cancer cells in response to different kinds of nanomaterials, including quantum dots, metallic and polymeric nanoparticles.

Design of Closed Seawater Recirculating Aquaculture System for Korean Rockfish Sebastes schlegeli Culture

  • Peng, Lei;Oh, Sung-Yong;Jo, Jae-Yoon
    • Ocean and Polar Research
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    • v.26 no.1
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    • pp.102-111
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    • 2004
  • Recirculating aquaculture system (RAS) consists of different treatment compartments that maintain water quality within the ranges commonly recommended for fish cultures. However, common RASs still exert considerable environmental impact since concentrations of organic matter and nutrients in their effluents are high. Compared with the traditional RAS, the model RAS developed here use a sedimentation basin for digestion purposes and then use the released volatile organic matter to stimulate a denitrification process. Different treatment compartments for solids, total ammonia nitrogen, and nitrate removal have been reviewed. This paper provides the basic information on designing different treatment compartments as well as the engineering criteria in closed seawater RAS, consisting of circular tanks for fish cultures; dual drain systems, sedimentation basins and foam fractionators for removal of solids; nitrification biofilters for TAN removal; denitrification biofilters for nitrate removal; and aerators for aeration. The main purpose is to outline a common procedure in designing of closed RAS for marine fish culture with an emphasis on easy management and low expense, as well as reduction of the environmental impact.

Component Procurement Planning with Demand Uncertainty Under Assemble-to-Order Environments (불확실한 수요를 갖는 주문 조립 환경에서의 부품 조달 계획에 관한 연구)

  • Lee, Geun-Cheol;Kim, Jung-Ug;Hong, Jung Man
    • Korean Management Science Review
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    • v.29 no.3
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    • pp.121-134
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    • 2012
  • In this study, we consider a component procurement planning problem where the procurement amounts of components are determined under assemble-to-order systems with demand uncertainty. In the problem, procurement amount of each component is decided before the demands of finished products are known and after the demands are identified the assembly amounts of the finished products are decided. In this study, the objective function of the problem is minimizing the total costs which are composed of purchase and inventory costs of the components and the backorder costs of the finished products. We assume that the uncertain demand information is given as multiple scenarios of the demands, and we propose procurement planning methods based on stochastic models which considering the multiple demand scenarios. To evaluate the performances of the proposed methods, computational experiments were carried out on the proposed methods as well as benchmarks including a method based on deterministic mathematical model and a heuristic. From the results of the computational tests, the superiorities of the proposed methods were shown.

A Design of Air Compressor Remote Control System Using USN Technology (USN 기술을 이용한 공기압축기 원격관리 시스템 설계)

  • Hwang, Moon-Young
    • Korean Journal of Artificial Intelligence
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    • v.6 no.1
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    • pp.1-10
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    • 2018
  • Compressed Air is an important energy source used in most factories nowadays. The automation trend using air compressor has been gradually increasing with the interest of the 4th industry in recent years. With the air compressor system, it is possible to construct the device at low cost and easily achieve automation and energy saving. In addition, With trend of FA, miniaturation and light weight manufacturing trend expand their use in the electronics, medical, and food sectors. Research method is to design the technology for the remote control of the following information as USN base. Development of flexible sensing module from real time observation module for fusion of IT technology in compressed air systems, design and manufacture of flexible sensing module, and realiability assessment. Design of real-time integrated management system for observation data of compressed air system - Ability to process observation data measured in real time into pre-processing and analysis data. This study expects unconventionally decreasing effect of energy cost that takes up 60~70% of air compressor layout and operation and maintenance management cost through USN(Ubiquitous Sensor Network) technology by using optimum operational condition from real time observation module. In addition, by preventing maintenance cost from malfunction of air compressor beforehand, maintenance cost is anticipated to cut back.

Visual Rhythm of Thriller Movies's Opening Title - Focusing on Identity (스릴러장르 영화 오프닝 시퀀스의 시각적 리듬 - '아이덴티티(Identity)'를 중심으로)

  • Shin, Seung-Yun;Sung, Bong-Sun;Kim, Jae-Ho
    • Journal of Korea Multimedia Society
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    • v.13 no.9
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    • pp.1365-1372
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    • 2010
  • Information of video can be percieved as the form of visual rhythm through temporal ordering systems. The shot, the base unit of video analysis, affects audience psychologicaliy with various temporal combination. Here, psychological stress and density of the story can be adjusted by the point of view shot of character. Acordingly the correlation analysis of shot duration and point of view shot can be useful for visual rhythm research. Identity one of the thriller genre works was selected for analyzing. This works produced by Kyle Cooper, a famous person in the opening sequence field. This works produced by Kyle Cooper, a famous person in the opening sequence field.

A Study on Strategies of Smart Green City - The Priority Analysis and Application of Planning Technique -

  • Lee, Seo-Jeong;Oh, Deog-Seong
    • KIEAE Journal
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    • v.15 no.2
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    • pp.5-17
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    • 2015
  • Purpose: The goal of this research is to identify the planning techniques of Smart Green City with Ubiquitous method and carbon-neutral city planning techniques and to induce the main planning techniques through the analysis of relative importance and practical adaptation. Method: First of all, eighteen planning techniques were derived and categorized into three organization systems and six sectors through literature review and FGI analysis considering the applicability of Ubiquitous service for carbon-neutral city planning techniques. Secondly, based on expert surveys and AHP analysis, the importance of Smart Green City planning techniques was evaluated. Thirdly, using case study, six cases related to Smart Green City were analyzed for the current status of application of planning techniques. Lastly, considering the importance of planning techniques and practical aspects, the characteristics of Smart Green City and its implication were estimated. Result: Energy, Resource and Waste and Transportation sector were identified as important sectors for Smart Green City. In addition, 'Construction of Smart Grid', 'System for Utilization of New & Renewable Energy', 'Smart Resource Circulation Management System', 'Establishment of Public Transportation Information System basis', 'Construction of Pedestrian / Bicycle oriented Road Environment' are essential planning techniques to create Smart Green City.

Automated Code Generation Framework for Industrial Automation Applications based on Timed Automata Model (타임드 오토마타 모델 기반 산업 자동화 응용 자동생성 프레임워크)

  • Lee, Kyunghyun;Kim, Ikhwan;Kim, Taehyoun
    • Journal of KIISE
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    • v.44 no.12
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    • pp.1307-1312
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    • 2017
  • Due to their convergence with state-of-the-art ICT technologies, the complexity and reliability demands of industrial automation systems have been rapidly increasing. In recent years, to cope with these demands, several research works have been carried out to adopt formal methods to the application development cycle at the early design stage. In this paper, we propose an automated code generation framework for industrial automation applications, based on a timed automata model. As a case study, we developed a formal model for a traffic light control system and verified the timing properties described in the specification. We finally demonstrated that the operation of a test-bed based on the auto-generated native code was identical to that of the model specification.

An Opportunistic Routing Scheme Based on Social Relations in Delay-Tolerant Networks (지연 감내 네트워크에서 사회관계기반 기회적 라우팅 기법)

  • Kim, Chan-Myung;Kang, In-Seok;Oh, Young-Jun;Han, Youn-Hee
    • KIPS Transactions on Computer and Communication Systems
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    • v.3 no.1
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    • pp.15-22
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    • 2014
  • Delay-Tolerant Network employs message forwarding based on a Store, Carry and Forward method to conquer no guarantee of continue connectivity. For this reason, a lot of DTN routing scheme have been proposed recently. message forwarding is an important research issue in delay-tolerant network and In this paper, we propose a efficiency DTN routing scheme using node's social relation and expanded Ego-network betweenness centrality. Our simulation results show that it is more efficient to message delivery cost than Epidemic routing, Friendship routing while it has a little performance degradation of message delivery ratio.

Automatic Creation of Forensic Indicators with Cuckoo Sandbox and Its Application (Cuckoo Sandbox를 이용한 포렌식 침해지표 자동생성 및 활용 방안)

  • Kang, Boong Gu;Yoon, Jong Seong;Lee, Min Wook;Lee, Sang Jin
    • KIPS Transactions on Computer and Communication Systems
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    • v.5 no.11
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    • pp.419-426
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    • 2016
  • As the threat of cyber incident grows continuously, the need of IOC(Indicators of Compromise) is increasing to identify the cause of incidents and share it for quick response to similar incidents. But only few companies use it domestically and the research about the application of IOC is deficient compared to foreign countries. Therefore in this paper, a quick and standardized way to create IOC automatically based on the analysis result of malwares from Cuckoo Sandbox and its application is suggested.

Enhancing Education Curriculum of Cyber Security Based on NICE (NICE 기반 사이버보안 교육커리큘럼 개선 연구)

  • Park, Wonhyung;Ahn, Seongjin
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.7
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    • pp.321-328
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    • 2017
  • As the cyber threats become more sophisticated and intelligent, the cases of cyber-infringement accidents are rapidly increasing. As a result, awareness of the importance of cyber security professionals has led to many cyber security-related educational programs. These programs provided with education curriculum aimed because cyber security workforce and job-based cyber security education research are not properly done. In this study, we developed a new cyber security education curriculum that defines and reflects cyber security personnel and knowledge system. In this study is not composed solely of the education contents related to the defenses emphasized in the existing education curriculum, but developed education curriculum to train a professional and balanced cyber security manpower by adding education contents in the attack field.