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Multi-Component Relaxation Study of Human Brain Using Relaxographic Analysis (Relaxographic 분석법을 이용한 뇌의 다중 자기이완특성에 관한 연구)

  • Yongmin Chang;Bong Soo Han;Bong Seok Kang;Kyungnyeo Jeon;Kyungsoo Bae;Yong-Sun Kim;Duk-Sik Kang
    • Investigative Magnetic Resonance Imaging
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    • v.6 no.2
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    • pp.120-128
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    • 2002
  • Purpose : To demonstrate that the relaxographic method provides additional information such as the distribution of relaxation times and water content which are poentially applicable to clinical medicine. Materials and Methods : First, the computer simulation was performed with the generated relaxation data to verify the accuracy and reliabilility of the relaxographic method (CONTINI). Secondly, in or der to see how well the CONTIN quantifies and resolves the two different ${T_1}$ environments, we calculated the oil to water peak area ratios and identified peak positions of ${T_1}-distribution$ curve of the phantom solutions, which consist of four centrifugal tubes (10 ml) filled with the compounds of 0, 10, 20, 30% of corn oil and distilled water, using CONTIN. Finally, inversion recovery MR images for a volunteer are acquired for each TI ranged from 40 to 1160 msec with TR/TE=2200/20 msec. From the 3 different ROIs (GM, WM, CSF), CONTIN analysis was performed to obtain the ${T_1}$-distribution curves, which gave peak positions and peak area of each ROI location. Results : The simulation result shows that the errors of peak positions were less in the higher peak (centered ${T_1}=600$ msec) than in the lower peak (centered ${T_1}=150$ msec) for all SNR but the errors of peak areas were larger in the higher peak than in the lower peak. The CONTIN analysis of the measured relaxation data of phantoms revealed two peaks between 20 and 60 msec and between 500 and 700 msec. The analysis gives the peak area ratio as oil 10%: oil 20%: oil 30% = 1:1.3:1.9, which is different from the exact ratio, 1:2:3. For human brain, in ROI 3 (CSF), only one component of -distributions was observed whereas in ROI 1(GM) and in ROI 2 (WM) we observed two components of ${T_1}-distribution$. For the WM and CSF there was great agreement between the observed ${T_1}-relaxation$ times and the reported values. Conclusion : we demonstrated that the relaxographic method provided additional information such as the distribution of relaxation times and water content, which were not available in the routine relaxometry and ${T_1}/{T_2}$ mapping techniques. In addition, these additional information provided by relaxographic analysis may have clinical importance.

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A standardized procedure on building spectral library for hazardous chemicals mixed in river flow using hyperspectral image (초분광 영상을 활용한 하천수 혼합 유해화학물질 표준 분광라이브러리 구축 방안)

  • Gwon, Yeonghwa;Kim, Dongsu;You, Hojun
    • Journal of Korea Water Resources Association
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    • v.53 no.10
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    • pp.845-859
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    • 2020
  • Climate change and recent heat waves have drawn public attention toward other environmental issues, such as water pollution in the form of algal blooms, chemical leaks, and oil spills. Water pollution by the leakage of chemicals may severely affect human health as well as contaminate the air, water, and soil and cause discoloration or death of crops that come in contact with these chemicals. Chemicals that may spill into water streams are often colorless and water-soluble, which makes it difficult to determine whether the water is polluted using the naked eye. When a chemical spill occurs, it is usually detected through a simple contact detection device by installing sensors at locations where leakage is likely to occur. The drawback with the approach using contact detection sensors is that it relies heavily on the skill of field workers. Moreover, these sensors are installed at a limited number of locations, so spill detection is not possible in areas where they are not installed. Recently hyperspectral images have been used to identify land cover and vegetation and to determine water quality by analyzing the inherent spectral characteristics of these materials. While hyperspectral sensors can potentially be used to detect chemical substances, there is currently a lack of research on the detection of chemicals in water streams using hyperspectral sensors. Therefore, this study utilized remote sensing techniques and the latest sensor technology to overcome the limitations of contact detection technology in detecting the leakage of hazardous chemical into aquatic systems. In this study, we aimed to determine whether 18 types of hazardous chemicals could be individually classified using hyperspectral image. To this end, we obtained hyperspectral images of each chemical to establish a spectral library. We expect that future studies will expand the spectral library database for hazardous chemicals and that verification of its application in water streams will be conducted so that it can be applied to real-time monitoring to facilitate rapid detection and response when a chemical spill has occurred.

An Analysis on Use Patterns of Oriental Medicine of Pond Wetland Plants for the Ecological Experience in Rural Tourism Village (농촌관광마을 생태체험을 위한 연못형습지 식물의 한방 이용형태 분석)

  • Son, Jinkwan;Kong, Minjae;Kang, Banghun;Kim, Miheui;Kang, Donghyeon;Lee, Siyoung;Han, Songhee
    • Journal of Wetlands Research
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    • v.19 no.2
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    • pp.230-239
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    • 2017
  • These days, the demand of farm tours is on the rise in Korea. However, most of them are related to farming experience. To overcome the situation, ecological experience is introduced. In this sense, it is necessary to obtain the contents and educational materials of ponds, the space of farming and ecological experience. Therefore, this study analyzed the use patterns of oriental medicine of pond wetland plants. Oriental medicine is used for old and traditional knowledge, and is still applied to various fields, such as medical science, pharmacy, and science. The analyzed result of this study will be helpful for the educational materials of ecological experience. This study surveyed plants of 40 pond wetlands in rural areas, and looked into the use patterns of traditional medicine by using the contents of Korea Traditional Knowledge Portal being operated by Korean Intellectual Property Office. According to the vegetation survey of the 40 pond wetlands, there were a total of 457 taxa in 108 families, 309 genera, 392 species, 59 varieties, 5 forma, and 1 subspecies. Among them, 314 taxa in 53 families, 136 genera, 265 species, 45 varieties, 3 forma, and 1 subspecies had the information on the use patterns of traditional medicine. It means that 68.8% of the plants around pond wetlands contain traditional medicine. Given other application patterns, such as food, handcraft and traditional farming, more than 70~80% are expected to include traditional knowledge. 314 taxa used for traditional medicine had 570 kinds of efficacy and 325 kinds of disease treatment. It means that one taxon has 4.0 (0~20) kinds of efficacy on average and 6.6(0~20) kinds of disease treatment. It is expected that this study result will be applied to various fields, including experience, education, and medical science. And it is considered that valuable pond wetlands are worthwhile to be conserved constantly.

Corrosion Characteristics of Excavated Bronze Artifacts According to Corrosion Environment (부식 환경에 따른 출토 청동 유물의 부식 특성)

  • Jang, Junhyuk;Bae, Gowoon;Chung, Kwangyong
    • Korean Journal of Heritage: History & Science
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    • v.53 no.1
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    • pp.24-33
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    • 2020
  • In excavated bronze artifacts, corrosion products of various shapes and colors are observed due to multiple corrosion factors coexisting in the burial environment, and these corrosion products can constitute important data not only in terms of long-term corrosion-related information, but also in connection with preservation of artifacts. As such, scientific analysis is being carried out on the corrosion layer and corrosion products of bronze artifacts, and the corrosion mechanism and the characteristics of corrosion products elucidated, which is essential for interpreting the exposed burial environment and its association with corrosion factors inside the burial environment. In this study, after classifying excavated bronze artifacts according to alloy ratio and fabrication technique, comprehensive analysis of the surface of corrosion artifacts, corrosion layer, and corrosion products was carried out to investigate the corrosion mechanism, formation process of the corrosion layer, and characteristics of corrosion products. The study designated two groups according to alloy ratio and fabrication technique. In Group 1, which involved a Cu-Sn-Pb alloy and had no heat treatment, the surface was rough and external corrosion layers were formed on a part, or both sides, of the inside and the outside, and the surface was observed as being green or blue. α+δ phase selection corrosion was found in the metal and some were found to be concentrated in an empty space with a purity of 95 percent or more after α+δ phase corrosion. The Cu-Sn alloy and heat-treated Group 2 formed a smooth surface with no external corrosion layer, and a dark yellow surface was observed. In addition, no external corrosion layer was observed, unlike Group 1, and α corrosion was found inside the metal. In conclusion, it can be seen that the bronze artifacts excavated from the same site differ in various aspects, including the formation of the corrosion layer, the shape and color of the corrosion products, and the metal ion migration path, depending on the alloy ratio and fabrication technique. They also exhibited different corrosion characteristics in the same material, which means that different forms of corrosion can occur depending on the exposure environment in the burial setting. Therefore, even bronze artifacts excavated from the same site will have different corrosion characteristics depending on alloy ratio, fabrication technique, and exposure environment. The study shows one aspect of corrosion characteristics in specific areas and objects; further study of corrosion mechanisms in accordance with burial conditions will be required through analysis of the corrosive layer and corrosive product characteristics of bronze artifacts from various regions.

Spatio-Temporal Incidence Modeling and Prediction of the Vector-Borne Disease Using an Ecological Model and Deep Neural Network for Climate Change Adaption (기후 변화 적응을 위한 벡터매개질병의 생태 모델 및 심층 인공 신경망 기반 공간-시간적 발병 모델링 및 예측)

  • Kim, SangYoun;Nam, KiJeon;Heo, SungKu;Lee, SunJung;Choi, JiHun;Park, JunKyu;Yoo, ChangKyoo
    • Korean Chemical Engineering Research
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    • v.58 no.2
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    • pp.197-208
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    • 2020
  • This study was carried out to analyze spatial and temporal incidence characteristics of scrub typhus and predict the future incidence of scrub typhus since the incidences of scrub typhus have been rapidly increased among vector-borne diseases. A maximum entropy (MaxEnt) ecological model was implemented to predict spatial distribution and incidence rate of scrub typhus using spatial data sets on environmental and social variables. Additionally, relationships between the incidence of scrub typhus and critical spatial data were analyzed. Elevation and temperature were analyzed as dominant spatial factors which influenced the growth environment of Leptotrombidium scutellare (L. scutellare) which is the primary vector of scrub typhus. A temporal number of diseases by scrub typhus was predicted by a deep neural network (DNN). The model considered the time-lagged effect of scrub typhus. The DNN-based prediction model showed that temperature, precipitation, and humidity in summer had significant influence factors on the activity of L. scutellare and the number of diseases at fall. Moreover, the DNN-based prediction model had superior performance compared to a conventional statistical prediction model. Finally, the spatial and temporal models were used under climate change scenario. The future characteristics of scrub typhus showed that the maximum incidence rate would increase by 8%, areas of the high potential of incidence rate would increase by 9%, and disease occurrence duration would expand by 2 months. The results would contribute to the disease management and prediction for the health of residents in terms of public health.

Dietitians' Customer Orientation at Contract Foodservice Management Company (위탁급식전문업체 영양사의 고객지향성 분석)

  • Shin, Seo-Young;Kim, Hee-Yeon;Choi, Mi-Kyung;Yang, Il-Sun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.6
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    • pp.801-808
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    • 2006
  • The purposes of this study were to measure customer orientation of dietitians engaged in contract foodservice management companies, and to examine the impacts of personal characteristics and organizational characteristics on the customer orientation of dietitians. The questionnaires developed for this study were distributed to 230 dietitians of contract foodservice management companies, including 4 major companies, in Seoul and Gyeonggi areas. A total of 187 (81.3%) questionnaires were used for analysis, and statistical analyses were conducted using SPSS (Win 11.5) for descriptive analysis, correlation analysis, t-test and ANOVA. The average customer orientation score of the dietitians was 3.77 (SD=0.40) and it seemed that most respondents evaluated themselves as customer-oriented. Further analyses revealed significant differences in customer orientation among different position (p<0.05) and payroll (p<0.01) groups.'Type of menu' also affected the customer orientation (p<0.01). Overall, it is needed to design efficient training programs that improve service skills and customer orientation of dietitians, and the understandings on variables affecting customer orientation would help it.

Optimum Design of Two Hinged Steel Arches with I Sectional Type (SUMT법(法)에 의(依)한 2골절(滑節) I형(形) 강재(鋼材) 아치의 최적설계(最適設計))

  • Jung, Young Chae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.12 no.3
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    • pp.65-79
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    • 1992
  • This study is concerned with the optimal design of two hinged steel arches with I cross sectional type and aimed at the exact analysis of the arches and the safe and economic design of structure. The analyzing method of arches which introduces the finite difference method considering the displacements of structure in analyzing process is used to eliminate the error of analysis and to determine the sectional force of structure. The optimizing problems of arches formulate with the objective functions and the constraints which take the sectional dimensions(B, D, $t_f$, $t_w$) as the design variables. The object functions are formulated as the total weight of arch and the constraints are derived by using the criteria with respect to the working stress, the minimum dimension of flange and web based on the part of steel bridge in the Korea standard code of road bridge and including the economic depth constraint of the I sectional type, the upper limit dimension of the depth of web and the lower limit dimension of the breadth of flange. The SUMT method using the modified Newton Raphson direction method is introduced to solve the formulated nonlinear programming problems which developed in this study and tested out throught the numerical examples. The developed optimal design programming of arch is tested out and examined throught the numerical examples for the various arches. And their results are compared and analyzed to examine the possibility of optimization, the applicablity, the convergency of this algorithm and with the results of numerical examples using the reference(30). The correlative equations between the optimal sectional areas and inertia moments are introduced from the various numerical optimal design results in this study.

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Assessment of Liquefaction Potential Using Correlation between Shear Wave Velocity and Normalized LPI on Urban Areas of Seoul and Gyeongju (정규화LPI와 전단파 속도의 상관관계를 활용한 서울과 경주 지역 액상화 위험도 평가)

  • Song, Young Woo;Chung, Choong Ki;Park, Ka Hyun;Kim, Min Gi
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.2
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    • pp.357-367
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    • 2018
  • Recent earthquakes in Gyeongju and Pohang have raised interest in liquefaction in South Korea. Liquefaction, which is a phenomenon that excessive pore pressure is generated and the shear strength of soil is decreased by repeated loads such as earthquakes, causes severe problems such as ground subsidence and overturning of structures. Therefore, it is necessary to identify and prepare for the possibility of liquefaction in advance. In general, the possibility of liquefaction is quantitatively assessed using the Liquefaction Potential Index (LPI), but it takes a lot of time and effort for performing site response analysis which is essential for the liquefaction evaluation. In this study, a simple method to evaluate the liquefaction potential without executing the site response analysis in a downtown area with a lot of borehole data was proposed. In this simple method, the correlation between the average shear wave velocity of the target location ground and the LPI divided by thickness of liquefiable layer was established. And the applicable correlation equation for various rock outcrop accelerations were derived. Using the 104 boreholes information in Seoul, the correlation equation between LPI and the shear wave velocity (ground water level: 0m, 1m, 2m, 3m) is obtained and the possibility of liquefaction occurrence in Seoul and Gyeongju is evaluated. The applicability of the proposed simple method was verified by comparing the LPI values calculated from the correlation equation and the LPI values derived using the existing site response analysis. Finally, the distribution map of LPI calculated from the correlation was drawn using Kriging, a geostatistical technique.

Studies on the Extractive Nitrogenous Constituents of Chum Salmon, Oncorhynchus keta in Korea (한국산 연어 (Oncorhynchus keta)의 함질소 엑스성분에 관한 연구)

  • PARK Choon-Kyu;SOUH Sang-Bok;LEE Eung-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.1
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    • pp.51-63
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    • 1996
  • In order to investigate the food quality of Korean chum salmon (Oncorhynchus keta) the composition of extractive nitrogenous components including the free amino acids, oligopeptides, nucleotides and related compounds, guanidino compounds, and quaternary ammonium bases were analyzed. The extractive nitrogen from the muscle ranged from 478 to 649 mg/100 g with little discrepancies by sex, sampling seasons and areas. The large amount of anserine was noted with fairly low level of taurine, alanine, glycine, glutamic acid and lysine in each extract. After Hydrolysis of the entracts remarkable increases were found in $\pi-methylhistidine,\;\beta-alanine$ from anserine and carnosine. The sum of nucleotides and related compounds of the muscle was $3.32\~9.22\;{\mu}mol/g$, and predominant compound was the inosine 5'-monophosphate. The lower glycinebetaine, $\beta-alaninebetaine$ and homarine were also found in some samples. The trimethylamine oxide content of the muscle was ranged from 107 to 148 mg, and the trimethylamine content was no move than 11 mg in all the collections. The concentrations of creatine in the muscle extracts ranged from 477 to 642 mg, and $8\~11mg$ for creatinine, respectively. The total nitrogens of the compounds analyzed for each samples accounted for more than $90\%$ of the extractive nitrogen in this study.

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Investigation of Post-seismic Sites Using Local Seismic Tomography in the Korean Peninsula (지진 토모그래피를 이용한 한반도의 과거진원지역의 특성 연구)

  • Kim So-Gu;Bae Hyung-Sub
    • Economic and Environmental Geology
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    • v.39 no.2 s.177
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    • pp.111-128
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    • 2006
  • Three dimensional crustal structure and source features of earthquake hypocenters on the Korean peninsula were investigated using P and S-wave travel time tomography. The main goal of this research was to find Vp/Vs anomalies at earthquake hypocenters as well as those of crustal structure of basins and deep tectonic settings. This allowed fer the extrapolation of more detailed seismotectonic force from the Korean peninsula. The earthquake hypocenters were found to have high Vp/Vs ratio discrepancies (VRD) at the vertical sections. High V/p/Vs ratios were also found in the sedimentary basins and beneath the Chugaryong Rift Zone (CRZ), which was due to mantle plume that subsequently solidified with many fractures and faults which were saturated with connate water. The hypocenters of most earthquakes were found in the upper crust for Youngwol (YE), Kyongju (KE), Hongsung (HE), Kaesong (KSE), Daekwan (DKE), and Daehung (DHE) earthquakes, but near the subcrust or the Moho Discontinuity for Mt. Songni (SE), Sariwon (SRE) and Mt. Jiri (JE) earthquakes. Especially, we found hot springs of the Daekwan, Daehung and Unsan regions coincide with high VRD. Also, this cannot rule out the possibility that there are some partial meltings in the subcrust of this region. High VRD might indicate that many faults and fractures with connate water were dehydrated when earthquakes took place, reducing shear modulus in the hypocenter areas. This is can be explained by due to the fact that a point source which is represented by the moment tensor that may involve changes in volume, shear fracture, and rigidity. High Vp/Vs ratio discrepancies (VRD) were also found beneath Mt. Backdu beneath 40 km, indicating that magma chamber existed beneath Mt. Backdu is reducing shear modulus of S-wave velocity.