• 약학회지
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• 제45권2호
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• pp.190-204
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• 2001

This study was conducted to investigate for its effects on reproductive and developmental toxicity of recombinant human epidermal growth factor (rhEGF) in Sprague-Dawley rats. Male rats were administered rhEGF at doses of 1, 10, 100, and 1000$\mu$g/kg/day, respective1y, by subcutaneous injection from 63 days before and throughout to mating period until the day before sacrifice. Female rats were administered rhEGF at the same doses from 14 days before mating to day 20 of gestation or to day 21 of lactation. We examined the male and female fertility indices and maternal toxicity of F0 parental animals. Also, we examined the external, visceral, or skeletal malformation of fetuses, growth and development, behavior, and/or reproductive performance of F1 animals. At the highest dose (1,000 $\mu$g/kg), the mean body weights of F0 animals were significantly increased in males and females at 3 or 2 weeks after treatment, respective1y. No clinical signs and food intakes were observed at any time during the experimental period by rhEGF treatment. In autopsy examination, the relative and absolute liver weights significantly increased in both sexes of 1,000 $\mu$g/kg. At the highest dose (1,000 $\mu$g/kg), there was a statistically significant increase of pregnancy period and the number of dead fetuses. Moreover, significant increase of mean fetal body weight and decrease of number of live fetuses, which related to the difficult dilivery were observed in highest dose group. In Fl examination, no adverse effects on external, visceral, and skeletal malformation, physical and functional development, behavior or reproductive ability of Fl animals were observed in any group. Also, there was no significant difference between control and treated groups in copulation or fertility indices of Fl animals. These results indicate that rhEGF had no adverse effect on fertility and reproductive ability of Sprague-Dawley rats.

• 한국산학기술학회논문지
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• 제21권11호
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• pp.385-397
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• 2020

본 연구는 북한이탈여성의 재북당시 생식건강 관련 경험을 탐색하고 성지식, 성태도, 생식건강 증진행위 수준을 확인하기 위해 수행된 수렴병렬 혼합설계 연구이다. 2020년 4월에서 7월까지 수도권에 거주하는 8명의 북한이탈여성을 눈덩이 방식으로 표집 후 심층면담하여 질적자료를 수집하였고 수도권, 충청권, 경상권에 거주하는 175명의 북한이탈여성을 편의표집하여 성지식, 성태도, 생식건강 증진행위에 대한 설문조사를 실시하였다. 심층면담 결과는 내용분석을 실시하였고, 설문 결과는 SPSS 23.0 프로그램을 이용하여 independent t-test, ANOVA, Pearson's Correlation Coefficients로 분석하였다. 질적자료 분석결과 북한이탈여성의 북한에서 경험한 생식건강 관련 경험은 '잘 알지 못하여 두려운 성', '의무만 강요하는 부끄럽고 귀찮은 성', '모든 것이 제한된 속에서 내가 스스로 알아서 관리해야하는 성'으로 나타났다. 양적자료 분석결과 대상자의 성지식은 연령이 높은 군과 기혼 군에서 높았고 성태도는 연령이 낮은 군에서 더 개방적인 것으로 나타났다. 생식건강 증진행위는 경제수준이 높은 군에서 더 활발하였고 성지식과 성태도는 양의 상관관계를 보였다. 국내에 정착한 대상자들이 재북기간에 가졌던 성에 대한 소극적인 태도를 극복하고 생식건강 증진행위를 수행할 수 있도록 지역사회의 지지체계 및 자원의 제공이 필요하며, 북한여성의 생식건강에 대하여 인도주의적 지원의 우선순위가 요구된다.

• Journal of Animal Science and Technology
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• 제62권6호
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• pp.875-883
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• 2020

This study was conducted to investigate the effects of group-housing facility (GHF), compared to an individual confinement stall (CON), on the reproductive performance, behavior, and stress hormones of gestating sows. A total of 50 primiparous sows (Landrace × Yorkshire) were randomly allocated into either CON (n = 25) or GHF (n = 25) during the gestation period. One week before parturition, the sows were transferred into conventional farrowing crates, and cross-fostering was conducted within 1 d of delivery. Blood was collected for analyses of stress indices at 75 d of gestation and postpartum. Reproductive performance was estimated during the period of birth to weaning. Behavior patterns were identified at 90 d of gestation. Litter size was not different between the CON and GHF treatments. Weaning to estrus interval, however, tended to be lower in the GHF than in the CON (p < 0.1). Activity, treating, belly nosing, and exploring behaviors were observed only in the GHF group, whereas rubbing was shown only with the CON. Serum cortisol concentration was lower in the GHF than in the CON at 75 d of gestation (p < 0.05). Sows housed in the GHF showed lower epinephrine and norepinephrine concentrations than those housed in the CON at postpartum (p < 0.05). The GHF sows demonstrated more natural behavior characteristics associated with stress relief than the CON sows with no adverse effects on reproductive performance. Therefore, these results suggest that GHF could be applied as an alternative housing facility to improve animal welfare on swine farms.

• 문화기술의 융합
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• 제10권2호
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• pp.439-446
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• 2024

본 연구는 간호대학생의 성지식, 성태도, 생식건강증진행위를 확인하고 이들의 상관관계 확인을 위한 서술적 조사연구이다. 간호대학생 300명을 대상으로 설문하고 229부로 분석하였다. 연구도구는 Jeon(2004)의 성지식, Ho(2009)의 성태도, Jo(2014)의 생식건강증진행위 측정도구를 사용하였다. 자료분석은 일반적 특성은 실수와 백분율, 평균과 표준편차, 성지식, 성태도, 생식건강증진행위는 평균과 표준편차를 이용하였다. 일반적 특성에 따른 성지식, 성태도, 건강증진행위 차이는 independent t-test, one-way ANOVA, 사후검정으로 Scheffe's test를 이용하였다. 상관관계는 Pearson's correlation coefficients로 분석하였다. 여학생의 성지식이 높았으며, 생식건강증진행위 교육은 저학년이 적절한 시기임을 알 수 있다. 또한, 성지식이 높을수록 생식건강증진행위가 높아 생식건강증진행위 향상을 위한 성교육의 필요성이 여전히 요구됨을 시사한다. 이에, 본 연구는 간호대학생의 생식건강을 위한 상담과 교육에 활용할 생식건강증진행위의 교육자료 개발에 기초자료로 활용될 수 있을 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제29권1호
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• pp.142-148
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• 2016

The present study investigated the effects of back-fat thickness at d 107 of gestation and housing types during gestation on reproductive performance and behavior of sows. A total of 64 crossbred sows ($Landrace{\times}Yorkshire$) in their 3 to 4 parities were allotted to one of four treatments (n = 16) over two consecutive parities. During each parity, sows were assigned to two gestational housing types (stall or group housing) and two level of back-fat thickness (<20 or ${\geq}20$) at d 107 of gestation. Gestating sows were transferred from gestational crates to stalls or pens (group housing) 5 weeks before farrowing. All sows were moved to farrowing crates on d 109 of gestation. At weaning, back-fat thickness changes were lesser (p<0.05) in sows having back-fat thickness <20 mm than that of sows with ${\geq}20mm$ back-fat thickness at 107 d of gestation. Group housed sows had greater (p<0.05) feed intake and shorter (p<0.05) weaning-to-estrus interval than that of sows in stalls. At weaning, back-fat thickness changes were lesser (p<0.05) in group housed sows than that of sows in stalls. The number of piglets at weaning, growth rate and average daily gain were greater (p<0.05) in group housed sows than that of sows in stalls. During gestation, walking duration was more (p<0.05) in group housed sows. Group housed sows had lesser (p<0.05) farrowing duration and greater (p<0.05) eating time than that of sows in stalls. Result obtained in present study indicated that sows with ${\geq}20mm$ back-fat thickness at 107 days had better reproductive performance. Additionally, group housing of sows during last five week of gestation improved the performance and behavior and reproductive efficiency of sows.

• 정보관리학회지
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• 제41권1호
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• pp.389-409
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• 2024

본 연구의 목적은 여대생들의 생식건강정보 탐색행위에 영향을 미치는 요인을 살펴보고 그 관계성을 살펴보는 것이다. 건강신념모델(HBM)과 계획된행동이론(TPB)을 기반으로 지각된 민감성, 지각된 심각성, 지각된 이익, 지각된 장애, 주관적 규범, 지각된 행동통제, 감정적 평가를 주요 요인으로 정의하고 연구를 설계하였다. 대학생 온라인 커뮤니티인 '에브리타임'을 통해 서울 소재 4년제 대학교의 여대생을 대상으로 온라인 설문을 실시하여 데이터를 수집하였다. 연구결과, 여대생들은 지각된 민감성, 지각된 이익, 주관적 규범이 높을수록, 반면에 지각된 장애는 낮을수록, 인터넷을 통해 생식건강정보를 탐색할 의도가 높은 것으로 나타났다. 또한 여대생들의 인터넷 생식건강 탐색에 영향을 미치는 요인들은 여대생들의 성경험 유무, 생식기계 질환 경험 유무, 건강관심도 등에 따른 그룹 간의 차이를 보이기도 했다. 본 연구결과는 여대생들을 대상으로 하는 대학도서관이나 보건기관 등이 온라인 건강정보 문해교육이나 관련 서비스 프로그램을 개발하는데 있어 여대생들의 생식건강 인식 정도를 파악하는데 기여할 수 있을 것으로 기대한다.

• 보건교육건강증진학회지
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• 제20권2호
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• pp.163-178
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• 2003

This study was done to examine knowledge and attitude towards sex and the needs for sex education of korea female students in college. Data for this study was collected through questionnaires filled-out by 464 female students from September 2002 to December 2002. The result of this study were as follows； The subjects' scores of sex knowledge was 19.60 on average devided into the lovest 1 to the highest 25. Reproductive physiology scored highest at 0.82 and the contraceptive method was the lowest at 0.54. The subjects showed a positive sex attitude as 48％ were for the abortions before marriage, a they appeared the most negative as 4.3％ were for extramarital coitus of women. The subjects who responded that sexual education is necessary were 423 (91.2％), and they wanted ‘the sexual mentality of men and women’ most, 419 (99.1％). Also, ‘contraceptive method’ of 404 (95.5％), ‘veneral disease.’, ‘sexual behavior’, ‘sexual physiology’, ‘reproductive physiology’, ‘sexual morals’ etc followed. Based on above results of the study, it is more essential to organize the sex education programs centering around ‘contraceptive method’, ‘veneral disease.’, ‘sexual behavior’ etc which are not too difficult but more needed than ‘reproductive physiology’. It is required to develope sex education programs through research between specialists in various fields rather than through specialists in one field. It is considered that sex education programs can lead female students to forming and maintaining a correct sexual identity.

• 부모자녀건강학회지
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• 제21권1호
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• pp.11-19
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• 2018

Purpose: This study aimed to explore the experiences and needs about sex education of university entrants in Korea, and to identify the relationship among the levels of sex-related knowledge, sexual attitude and reproductive health promoting behavior. Methods: Totally 188 freshman year of two different university were recruited to reply. The design of study was a exploratory research, using a cross-sectional survey. A self-administered questionnaire was used to measure the experiences and needs about sex education. The data were analyzed with the SPSS/WIN 21.0 program. Results: 95.2% of the experienced sex education but the level of satisfaction about sex education was 38.3%. The sex education methods that subjects wanted were comfortable and interesting using videos and practices. Sex-related knowledge significantly differed according to sex. Sexual attitude differed according to the experience of sex, the line of dating and the route of information about sex. There was positive correlations among sex-related knowledge, sexual attitude and reproductive health promoting behavior of female entrants. Conclusion: So sex education program, composed of knowledge, attitude and behavior should be interesting and helpful in order to fit current trends and fulfill university entrants' needs.

• Child Health Nursing Research
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• 제24권3호
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• pp.329-336
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• 2018

Purpose: This study analyzes the effects of smoking behaviors of women of reproductive ages in terms of maternal conditions and conditions arising during the perinatal period in Korea. Methods: We used the National Health Insurance Corporation's medical panel data. Subjects included 382 individuals suffering from maternal conditions and conditions arising during the perinatal period from 2013 to 2014. A t-test was used to analyze the individual differences between maternal conditions and conditions arising during the perinatal period-A hierarchical regression analysis was performed in two steps to measure the effects of smoking behaviors on diseases. Results: The amount and duration of smoking are significant factors causing maternal conditions and conditions arising during the perinatal period. In the regression analysis, the explanatory power of model was significantly increased by adding smoking behavior to the maternal conditions and conditions arising during the perinatal period. Smoking behavior during pregnancy displayed a significant influence on diseases. Conclusion: Results of this study showed that the effects of smoking behavior on maternal conditions and conditions arising during the perinatal period were significant. Therefore it is necessary to develop a smoking cessation education program for pregnant women in Korea.

• 동서간호학연구지
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• 제23권1호
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• pp.9-17
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• 2017

Purpose: Due to today's sexual openness, college students may be exposed to frequent sexual relations, which can affect their adulthood reproductive health, pregnancy, and delivery. The purposes of this study were to explore the degrees of sexual knowledge, sexual attitudes, and reproductive health promoting behaviors in male and female college students and to identify their gender differences. Methods: A descriptive comparative design was used. A total of 181 college students(92 male and 89 female) were recruited. Data were collected between March 17 and April 8, 2016 using a convenience sample in a university located in Y city. Results: For male students, there was no correlation between two variables. For female students, reproductive health promoting behaviors had a significant relationship with sexual attitudes. Conclusion: These findings provide essential information that health care providers can use to increase their awareness of the importance of gender specific treatments when caring individuals.