• Title/Summary/Keyword: Reproductive Management

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Regional Variance of Late Preterm Birth in Seven Metropolitan Cities of Korea: 2008-2012 (우리나라 대도시의 지역별 후기조기분만 발생에 관한 연구: 2008-2012)

  • Lim, Dar-Oh;Park, Sang-Hwa
    • The Korean Journal of Health Service Management
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    • v.8 no.3
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    • pp.147-155
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    • 2014
  • The objective of the study was to analyze the regional variance of late preterm birth (LPT: 34-36 weeks) by analyzing 2008-2012 birth certificated data of seven metropolitan cities (536,984 births: primiparous singleton birth) from Korea Statistics. The odds ratio and 95% confidence intervals were calculated from multinominal logistic regression analyses to describe the regional variance of LPT adjusted for maternal and infantile variables. The highest incidence of LPT rate by region were observed in Ulsan metropolitan city (3.7 percent), and the lowest in Deajon metropolitan city (3.1 percent). After adjustment by logistic regression for infantile sex, maternal variables, there was a significant increase in the risk of late preterm birth in Ulsan metropolitan city (odds ratio: 1.21) as compared with the incidence of LPT in Deajon metropolitan city. The odds ratio of LPT by region were 1.17 in Daegu metropolitan city, 1.13 Busan metropolitan city, and 1.12 in Incheon metropolitan city. More research is required to understand the risk factors for late preterm birth in this area including socio-demographic factors, medical factors, and regional and environmental factors.

Pattern of Sexual Dimorphism in Garcinia kola (Heckel) Plantation

  • Henry Onyebuchi, Okonkwo;Godwin Ejakhe, Omokhua;Uzoma Darlington, Chima
    • Journal of Forest and Environmental Science
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    • v.38 no.4
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    • pp.275-283
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    • 2022
  • A study was designed to investigate the pattern of sexual dimorphism in a plantation of Garcinia kola. Twenty trees were randomly selected for the study and have been observed to flower regularly. A total of 100 inflorescence were randomly collected from the crown of each tree and 500 flowers randomly assessed within the period of four (4) flowering seasons. Floral sex assessment was done visually and with a hand magnifying lens; floral morphometric measurements (i.e. pedicel and perianth length and breadth), inflorescence length, and breadth) was taken using a veneer caliper; number of flowers per inflorescence and inflorescence per twig was counted; while, data analysis was conducted on excel using analysis of variance and pairwise t-test comparison. Four floral sexes were identified in the G. kola plantation studied which were unisexual male flowers, unisexual female flowers, cosexual unisexual male flowers, and cosexual hermaphrodite flowers. Three tree sexes were identified viz: inconstant male, invariant female, and cosexual trees. The plantation was significantly sexually dimorphic in floral sex and phenotypic traits (i.e. pedicel and perianth size), and as well as sexually dimorphic in tree sex and reproductive phenotypic traits (i.e. inflorescence size, number of inflorescences per twig, and number of flower bud per inflorescence). The sexual system of the plantation was therefore trioecious with features suggestive of evolving dioecy through the gynodioecious pathway.

A Review of Clinical and Preclinical Studies on the Therapeutic Potential of Black Seeds (Nigella sativa) in the Management of Polycystic Ovarian Syndrome (PCOS)

  • Rajkapoor Balasubramanian;Naina Mohamed Pakkir Maideen;Sudha Muthusamy;Mirunalini Gobinath
    • Journal of Pharmacopuncture
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    • v.26 no.1
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    • pp.1-9
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    • 2023
  • Objectives: Polycystic ovary syndrome (PCOS) is a condition that occurs frequently among women of reproductive age and is a polygenic, multifactorial, endocrine, and metabolic disorder. PCOS is becoming more common as a result of risk factors such as current lifestyle, overnutrition, and stress. The use of traditional herbal medicine is higher among the global population. Hence, this review article focuses on the potential of Nigella sativa to manage women with PCOS. Methods: A literature search was carried out using databases including Medline, Google Scholar, EBSCO, Embase, and Science Direct, as well as reference lists, to identify relevant publications that support the use of N. sativa in the management of women with PCOS. Results: Several clinical and preclinical studies have demonstrated that the major bioactive constituent of black seed (N. sativa), thymoquinone, has potential for managing women with PCOS. Moreover, N. sativa may help to manage oligomenorrhea and amenorrhea in women with PCOS through its anti-inflammatory and antioxidant properties. Conclusion: N. sativa has potential for use as a herbal medicine for managing women with PCOS as an integrative medicine along with traditional and modern medicine in conjunction with calorie restriction and regular exercise.

Intergenerics Nuclear Transfer Technology for Conservation of Endangered Species

  • Lee, B.C.;S.K. Kang;J.K. Cho;B. Bavister;W.S. Hwang
    • Proceedings of the Korean Society of Embryo Transfer Conference
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    • 2002.11a
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    • pp.56-62
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    • 2002
  • The International Union for Conservation of Nature and Natural Resources (IUCN) considers the western/lowland bongo Tragelaphus eurycerus eurycerus to be a threatened species, and the eastern/mountain bongo Tragelaphus eurycerus isaaci an endangered species[1]. Although extinction is considered by many biologists to be a natural process during evolution, the exponential growth of the human population has drastically and prematurely reduced the numbers and genetic diversity of many species[2]. Species have evolved to adapt to a specific habitat or environment that meet their survival needs. Alteration or destruction of their habitat results in a species becoming incapable of adapting and hence becoming threatened with extinction. A widespread scientific and public consensus has emerged suggesting that governments should assign high priority to the maintenance of biological diversity via habitat preservation and management far species conservation[3]. Unfortunately, the loss of biological diversity far surpasses the available conservation resources and species are lost forever on a daily basis[4]. Notwithstanding the focus on habitat preservation and wildlife management, conservation biologists have also become increasingly interested in using the technologies of reproductive and developmental biology to help manage or rescue endangered species[5].

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Antibiotic resistance in Neisseria gonorrhoeae: broad-spectrum drug target identification using subtractive genomics

  • Umairah Natasya Mohd Omeershffudin;Suresh Kumar
    • Genomics & Informatics
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    • v.21 no.1
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    • pp.5.1-5.13
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    • 2023
  • Neisseria gonorrhoeae is a Gram-negative aerobic diplococcus bacterium that primarily causes sexually transmitted infections through direct human sexual contact. It is a major public health threat due to its impact on reproductive health, the widespread presence of antimicrobial resistance, and the lack of a vaccine. In this study, we used a bioinformatics approach and performed subtractive genomic methods to identify potential drug targets against the core proteome of N. gonorrhoeae (12 strains). In total, 12,300 protein sequences were retrieved, and paralogous proteins were removed using CD-HIT. The remaining sequences were analyzed for non-homology against the human proteome and gut microbiota, and screened for broad-spectrum analysis, druggability, and anti-target analysis. The proteins were also characterized for unique interactions between the host and pathogen through metabolic pathway analysis. Based on the subtractive genomic approach and subcellular localization, we identified one cytoplasmic protein, 2Fe-2S iron-sulfur cluster binding domain-containing protein (NGFG RS03485), as a potential drug target. This protein could be further exploited for drug development to create new medications and therapeutic agents for the treatment of N. gonorrhoeae infections.

Conceptual Model for Women s Health (여성건강을 위한 개념적 모형)

  • 이경혜
    • Journal of Korean Academy of Nursing
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    • v.27 no.4
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    • pp.933-942
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    • 1997
  • There has recently been an increased interest in women's health from, various disciplines, with different perspectives presented according to each profession's academic background. This has led to many instances of incorrectly defining, or misinterpretation, of the issues even among professionals. Nurse scholars as well as practitioners who work in women's health care need to have a clear conceptual understanding of women's health in order to build a body of knowledge, delineate curricular activities, and set directions for professional nursing interventions. In addition, a conceptual model that may be directly utilized in practice is needed to maintain and promote women's health issues. The purpose of this study was to apply a Hybrid model, analyzing conceptual definitions and discussions related to women's health gathered from review of the literature. Further to compare analyticals the concepts and properties observed from field work, so as to present a final definition of women's health and, build a conceptual framework for a united comprehensive perspective on the concept as well as on nursing practice. Data collection and analysis consisted of a theoretical stage, field work stage, and final analysis. A heterogeneous group of professionals and lay persons, 39 in all, participated in the field work. Study findings Include several subconcepts under the concept of women's health : a woman's whole life, holistic health, quality of life, awareness of being a woman, individual nursing, self care ability, reproductive health, and family health. Thus, a comprehensive definition was built, 1. e., "Women's health care be defined as improvement in the quality of life of women through attainment of holistic health throughout the life span. With reproductive health at the core, the concept is directly related to family and national health, and includes taking care of one's own health based on awareness of being a woman and utilizing self care activities. Women's health care issues are unique and allow various responses, therefore women's health professionals need to apply individual approaches to reach solutions in attaining holistic health and improving quality of life." The constructual factors of women's health were found to be reproductive functions, diseases more common in woman, self actualization, mental health, women's health policies, sexuality, midlife changes, and marital relations, with each factor having more than three properties. Positive factors affecting women's health were found to be a normal childbearing process, a healthy lifestyle, active health management, health information, support, and resources, and interpersonal relationships. Negative factors were found to be overwhelming role stress, cultural oppression, gender inequality, distorted sexual identity, economic difficulties, misuse and/or abuse of substances, and stress. The model of women's health may be visualized as a balance scale set upon a woman's life, supporting 4 concentric circles. The innermost circle and second circle incorporate conceptual definitions of women's health, and the outer two circles represent the constructional factors and properties of women's health. Each circle has its own color that symbolizes the conceptual meaning. Positive and negative factors are represented as weights at either end of the scale, and are affected by nursing intervention, i. e., health and wellness increase when positive factors are stronger, whereas disease and illness increase when negative factors are stronger. This model is only a preliminary effort and requires much discussion and testing to be further developed. Continuous research is also required.

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Effects of Twin Birth on the Occurrence of Postpartum Disorders, Culling and Reproductive Performance, and its Risk Factors in Dairy Cows (젖소에서 쌍태분만이 산후질병 발생, 도태 및 번식능력에 미치는 영향과 쌍태 위험 요인)

  • Kim, Ill-Hwa;Kang, Hyun-Gu
    • Journal of Veterinary Clinics
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    • v.28 no.4
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    • pp.339-343
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    • 2011
  • This study determined the effects of twin birth on subsequent postpartum disorders, culling and reproductive performance, and its risk factors in dairy cows. Detailed data related to reproduction, health, and calving events, including dates of artificial insemination (AI) and calving, hormonal treatment prior to conception, cow parity, twin birth, retained placenta, metabolic disorders, and endometritis were collected from 1,717 individual calvings on 9 dairy farms. The incidence rate of twin birth was 3.4%. Gestation length was shorter in cows with twin birth ($270.6{\pm}2.0$ days) than cows giving birth to singletons ($279.5{\pm}0.2$ days, P < 0.01). The incidence of retained placenta (47.5 vs. 16.0%), metabolic disorders (18.6 vs. 3.8%) endometritis (62.7 vs. 28.2%), and culling rate (32.2 vs. 16.5%) was greater in cows with twin birth than in cows giving birth to singletons, respectively (P < 0.01). The hazard of pregnancy (adjusted hazard ratio, AHR) by 210 days in milk analyzed using Cox proportional hazards model was affected by calving season, in that the rate of pregnancy for cows calved during spring was less than for cows calved during winter (AHR = 0.80; P = 0.01); this was also true for endometritis (AHR = 0.46, P < 0.01). AHR was not affected by twin birth. Logistic analysis demonstrated that increasing the cow parity (P < 0.01) and hormonal treatment prior to conception (adjusted odds ratio, AOR = 1.84, P < 0.05) increased the risk of twin birth. These results demonstrate that twin births are responsible for severe economic losses through the increased occurrence of postpartum disorders and culling; thus, appropriate management for the deleterious impact of twin birth, and/or reducing the risk factors by herd control regarding cow parity and the use of reproductive hormones prior to conception might be necessary.

Comparison among the Sperm Preparation Methods on the Human Spermatozoa (인간정자에 있어서 정자처리법의 비교)

  • Pang, Myung-Geol;Chung, Ku-Min;Shin, Chang-Jae;Kim, Jung-Gu;Moon, Shin-Yong;Chang, Yoon-Seok;Lee, Jin-Yong;Lee, Sang-Hoon;Chung, Yung-Chai;Kim, Chang-Keun
    • Clinical and Experimental Reproductive Medicine
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    • v.20 no.2
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    • pp.107-115
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    • 1993
  • Procedures to separate motile. normal & motile and acrosome-reacted sperm with high efficiency have clinical application in Assisted Reproductive Technology in terms of increasing the probability of fertilization by a normal sperm and subsequent normal embryonic development. This study evaluated the effects of 10 sperm preparation techniques [Swim-up from a washed pellet (SU). Swim-up from semen (SO). Continuous Percoll Gradients I (PIC). Discontinuous Percoll Gradients I (PID). Continuous Percoll Gradients II(P II C). Discontinuous Percoll Gradients II(P II D), SpermPrep (SFC). Wang's tube (WT). Albumin Gradients (AG), Low temperature capacitation (LTC)] on motility (%), normal morphology (%), motile sperm recovery rate(%). morphologically normal & motile sperm recovery rate (%), true acrosome reaction (%) and fertilizing ability. A P II D proved to be an effective means of separating morphologically normal & motile sperm. Our results indicated the P II D has advantages as compared with other methods in terms of recovery rate. enhancement of motility and normal morphology. And a LTC seems to be an effective means of enhancing the true acrosome reaction and fertilizing ability. These results suggest that the combined method of LTC and P II D for separation of morphologically normal & motile sperm and acrosome reacted sperm may be a useful procedure for intrauterine insemination and in vitro fertilization in the management of male factor infertility as well as for isolation of subpopulation of sperm for basic research.

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Effects of Breed, Insemination Time, Sperm Concentration, Farm and Year on Reproductive Performance of Sows Inseminated by Frozen Boar Semen (돼지에서 동결정액을 이용한 인공수정시 종모돈의 품종, 인공수정 횟수, 정자농도, 농장 및 연도가 번식성적에 미치는 영향)

  • 김인철;이장희;김현종;이성호;박창식
    • Korean Journal of Animal Reproduction
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    • v.26 no.2
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    • pp.111-117
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    • 2002
  • This study was carried out to investigate the effects of frozen boar semen on reproductive performance in swine artificial insemination (AI). Many factors, which were breeds, time of insemination, sperm concentration per dose, farm and year were investigated to improve reproductive performance efficiency. Boars were raised at Swine Artificial Insemination Center in National Livestock Research Institute, Sunghwan, Chungnam, Korea. This experiment was carried out from 1995 to 2000. There were no differences in swine AI with frozen boar semen using 5$m\ell$ maxi-straw among 3 breeds (Landrace, Yorkshire, Duroc), 2 or 3 times insemination per estrus, and 3 different sperm numbers of 3.0, 4.0, and 5.0$\times$10$^{9}$ per dose of insemination. However, non-return rate and litter size of sows inseminated with frozen boar semen of commercial farms were different according to farm management system and inseminator's skill. Conception rate, farrowing rate and number of pigs born alive per litter by artificial insemination with frozen boar semen (5$m\ell$ maxi-straw) from 1995 to 1999 was 68.3~74.6%, 61.7~67.6% and 8.1~8.7 heads.

Effect of Moisture and Nutrient of Soil on Reproductive Phenology and Physiological Response of Epilobium hirsutum L., an Endangered Plant (토양의 수분과 유기물이 멸종위기식물 큰바늘꽃(Epilobium hirsutum L.)의 번식계절 및 생리 반응에 미치는 영향)

  • Lee, EungPill;Lee, SooIn;Han, YoungSub;Lee, SeungYeon;You, YoungHan;Cho, YiYun
    • Journal of Wetlands Research
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    • v.20 no.1
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    • pp.27-34
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    • 2018
  • Reproductive phenology and physiological responses of Epilobium hirsutum L. to moisture content and nutrient content of soil were analysed in order to obtain basic data for effective conservation and restoration. Epilobium hirsutum L. is a perennial plant. But Epilobium hirsutum L. grew reproductively in all moisture and nutrient gradients. Flower bud, flowers and peduncle were respectively ripened in earlier under highest moisture condition and highest nutrient condition. And, number of flowers and peduncle were more quickly increased under highest moisture condition and highest nutrient condition. Chlorophyll content was high under highest moisture condition and higher middle moisture condition. However, we found no significant difference of chlorophyll content regard to nutrient gradients. There was no difference in minimum chlorophyll fluorescence among all moisture and nutrient gradients. The photochemical efficiency values of PS II were 0.75 in all moisture gradients, and it was 0.78 in highest nutrient gradient. The chlorophyll content of Epilobium hirsutum L. increased as the moisture content increased, and the Fv/Fm value increased as the organic matter increased. Our results showed that high moisture and nutrient content of soil advance their breeding season and promote reproductive growth. It might be important basic informations for the maintenance of population and the management of habitat of Epilobium hirsutum L. an endangered plant species.