• Proceedings of the IEEK Conference
• /
• 2003.07d
• /
• pp.1621-1624
• /
• 2003

As the entities participating Grid become larger, performance requirement for the LDAP-based GIS(Grid Information Service) goes beyond that provided by a stand-alone single LDAP server. This entails the exploration of distributed LDAP systems. This paper presents the performance evaluation respectively for a distribution-based and a replication-based LDAP model. The analysis is based on an analytic performance model for each distributed system which is obtained by applying the M/M/1 queuing model. The performance evaluation made to these analytic models reveals that the distribution-based and the replication-based model show a significant tradeoff in their performance with respect to the system size as well as the amount of system load.

• Journal of Conservation Science
• /
• v.37 no.1
• /
• pp.25-33
• /
• 2021

To extend the application of digital technology to the replication of artifacts, meticulous details of the process and the diversity of three-dimensional (3D) printing output materials need to be supplemented. Thus, in this study, a bronze mirror with Hwangbichangcheon inscription was digitalized by 3D scanning, converted into a voxel model, and virtual conservation treatment was performed using a haptic device. Furthermore, the digital mold of the bronze mirror completed by Boolean modeling was printed using a 3D sand-printer. Such contactless replication based on digital technology reflects the stability, precision, expressivity, collectivity, durability, and economic feasibility of artifacts. Its application can be further extended to cultural products as well as such areas as education, exhibition, and research. It is expected to be in high demand for metal artifacts that require casting. If empirical studies through experimental research on casting are supplemented in the future, it could extend the application of digital technology-based contactless replication methods.

• Journal of Korean Society for Geospatial Information Science
• /
• v.5 no.2 s.10
• /
• pp.193-205
• /
• 1997

It is required for multi-users to share massive mapping data effectively that distributed data model in the Client-Server environment is developed for the replication consistency. The existing model is not effective to the long transaction just like a mapping system, since it does not account lot consistency between GUI screen and database replications even though it emphasizes on the replication consistency. The performance of concurrency control is very important for those long transactions, especially the mapping systems. This model is to support consistency between GUI screen and replicas using display locks. It suggests consistency model improving process performance by modifying memory consistency model and optimistic concurrency control for mapping data's characteristics.

• Journal of Internet Computing and Services
• /
• v.6 no.1
• /
• pp.73-84
• /
• 2005

ALTIBASE/sup TM/ is the relational main-memory DBMS in which a main memory is primarily used as the main storage device. We present the database replication strategies and techniques of the ALTIBASETM system in order to meet the requirement of high availability and efficient transaction processing. Our process architecture for replication management and its communication model are proposed, and database replication protocols are also described. We show the experimental result of transaction processing rate with various DBMS parameters and overall performance of database replication system as compared to standalone system.

• Proceedings of the Korean Society of Plant Pathology Conference
• /
• 2003.10a
• /
• pp.14-14
• /
• 2003

Potato virus X (PVX), the type member of Potexvirus genus, is a flexuous rod-shaped virus containing a single-stranded (＋) RNA. Infection by PVX produces genomic plus- and minus-strand RNAs and two major subgenomic RNAs (sgRNAs). To understand the mechanism for PVX replication, we are studying the cis- and/or trans-acting elements required for RNA replication. Previous studies have shown that the conserved sequences located upstream of two major sgRNAs, as well as elements in the 5' non-translated region (NTR) affect accumulation of genomic and sg RNAs. Complementarity between sequences at the 5' NTR and those located upstream of two major sgRNAs and the binding of host protein(s) to the 5' NTR have shown to be important for PVX RNA replication. The 5 NTR of PVX contains single-stranded AC-rich sequence and stem-loop structure. The potential role(s) of these cis-elements on virus replication, assembly, and their interaction with viral and host protein(s) during virus infection will be discussed based on the data obtained by in vitro binding, in vitro assembly, gel shift mobility assay, host gene expression profiling using various mutants at these regions.

• Journal of Microbiology and Biotechnology
• /
• v.30 no.9
• /
• pp.1412-1419
• /
• 2020

Human noroviruses (HuNoVs) are a leading cause of gastroenteritis outbreaks worldwide. However, the paucity of appropriate cell culture models for HuNoV replication has prevented developing effective anti-HuNoV therapies. In this study, first, the replication of the virus at various temperatures in different cells was compared, which showed that lowering the culture temperature from 37℃ significantly increased virus replication in Madin-Darby canine kidney (MDCK) cells. Second, the expression levels of autophagy-, immune-, and apoptosis-related genes at 30℃ and 37℃ were compared to explore factors affecting HuNoV replication. HuNoV cultured at 37℃ showed significantly increased autophagy-related genes (ATG5 and ATG7) and immune-related genes (IFNA, IFNB, ISG15, and NFKB) compared to mock. However, the virus cultured at 30℃ showed significantly decreased expression of autophagy-related genes (ATG5 and ATG7), but not significantly different major immune-related genes (IFNA, ISG15, and NFKB) compared to mock. Importantly, expression of the transcription factor FOXO1, which controls autophagy- and immune-related gene expression, was significantly lower at 30℃. Moreover, FOXO1 inhibition in temperature-optimized MDCK cells enhanced HuNoV replication, highlighting FOXO1 inhibition as an approach for successful virus replication. In the temperature-optimized cells, various HuNoV genotypes were successfully replicated, with GI.8 showing the highest replication levels followed by GII.1, GII.3, and GII.4. Furthermore, ultrastructural analysis of the infected cells revealed functional HuNoV replication at low temperature, with increased cellular apoptosis and decreased autophagic vacuoles. In conclusion, temperature-optimized MDCK cells can be used as a convenient culture model for HuNoV replication by inhibiting FOXO1 and providing adaptability to different genotypes.

• Proceedings of the IEEK Conference
• /
• 2003.11b
• /
• pp.3-6
• /
• 2003

In this paper, we conduct a performance analysis for the composite scheme that is obtained by combining the data distribution and the data replication schemes usually used for the implementation of distributed directory service systems. The analysis results reveal that the composite model is a viable option to overcome the performance trade-off between the data distribution and the data replication model. In this paper, we present the performance model developed for the composite model by appling queuing modelling. Using the performance model, performance values for a variety of system execution environments are suggested which enable us to bring an efficient design for high performance distributed directories.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.5
• /
• pp.2449-2456
• /
• 2013

The column-oriented database storage is a very advanced model for large-volume data analysis systems because of its superior I/O performance. Traditional data storages exploit row-oriented storage where the attributes of a record are placed contiguously in hard disk for fast write operations. However, for search-mostly datawarehouse systems, column-oriented storage has become a more proper model because of its superior read performance. Recently, solid state drive using MLC flash memory is largely recognized as the preferred storage media for high-speed data analysis systems. In this paper, we introduce fast column-oriented data storage model and then propose a new storage management scheme using a cross compressed replication for the high-speed column-oriented datawarehouse system. Our storage management scheme which is based on two MLC SSD achieves superior performance and reliability by the cross replication of the uncompressed segment and the compressed segment under high workloads of CPU and I/O. Based on the results of the performance evaluation, we conclude that our storage management scheme outperforms the traditional scheme in the respect of update throughput and response time of the column segments.

• The Plant Pathology Journal
• /
• v.24 no.3
• /
• pp.289-295
• /
• 2008

RNA-RNA interactions and the dynamic RNA conformations are important regulators in virus replication in several RNA virus systems and may also involved in the regulation of many important virus life cycle phases, including translation, replication, assembly, and switches in these important stages. The 5' non-translated region of Potato virus X(PVX) contains multiple cis-acting elements that facilitate various viral processes. It has previously been proposed that RNA-RNA interactions between various RNA elements present in PVX RNA genome are required for PVX RNA accumulation(Hu et al., 2007; Kim and Hemenway, 1999). This model was based on the potential base-pairing between conserved sequence elements at the upstream of subgenomic RNAs(sgRNAs) and at the 5' and 3' end of RNA genome. We now provide more evidence that RNA-RNA base-pairing between elements present at the 5' end and upstream of each sgRNA is required for efficient replication of genomic and subgenomic plus-strand RNA accumulation. Site-directed mutations introduced at the 5' end of plus-strand RNA replication defective mutant(${\Delta}12$) increasing base-pairing possibility with conserved sequence elements located upstream of each sgRNAs restored genomic and subgenomic plus-strand RNA accumulation and caused symptom development in inoculated Nicotiana benthamiana plants. Serial passage of a deletion mutant(${\Delta}8$) caused more severe symptoms and restored wild type sequences and thus retained possible RNA-RNA base-pairing. Altogether, these results indicate that the RNA element located at the 5' end of PVX genome involved in RNA-RNA interactions and play a key role in high-level accumulation of plus-strand RNA in vivo.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2010.05a
• /
• pp.151-152
• /
• 2010