• Journal of Microbiology and Biotechnology
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• 제27권2호
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• pp.207-218
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• 2017

Clustered regulatory interspaced short palindromic repeats (CRISPR) in association with CRISPR-associated protein (Cas) is an adaptive immune system, playing a pivotal role in the defense of bacteria and archaea. Ease of handling and cost effectiveness make the CRISPR-Cas system an ideal programmable nuclease tool. Recent advances in understanding the CRISPR-Cas system have tremendously improved its efficiency. For instance, it is possible to recapitulate the chronicle CRISPR-Cas from its infancy and inaugurate a developed version by generating novel variants of Cas proteins, subduing off-target effects, and optimizing of innovative strategies. In summary, the CRISPR-Cas system could be employed in a number of applications, including providing model systems, rectification of detrimental mutations, and antiviral therapies.

• 전기학회논문지
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• 제65권12호
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• pp.2113-2118
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• 2016

The precise detection of electric leakage point of underground power cable is very important to reduce cost and time of maintenance and prevent electric shock accident through expedite repair of electric leakage point. This paper proposes a electric leakage point detection system underground power cable using of half-period modulated transmission waveform and earth electric potential measurement. The developed system is composed of transmitter to generate the wanted pulse waveform, receiver to measure and display earth electric potential by the transmitted pulse in electric leakage point and PC Software program to display of GPS coordinate on detection cable line. The performance of the electric leakage point detection system was tested in the constructed underground cable leakage detection test bed. The test results on signal generation voltage precision of signal transmitter, mean detection earth voltage, mean detection leakage current and electric leakage point detection error showed the developed system can be used in electric leakage point detection underground power cable.

• Structural Engineering and Mechanics
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• 제15권1호
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• pp.53-70
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• 2003

The motivation of this paper is to introduce the modern technology of large-scale cooling tower design. Thereby the innovative design concept for the world's largest cooling tower with a height of 200 m is briefly presented (Harte & Kr$\ddot{a}$tzig 2002, Bush et al. 2002). The new concept was considered not only for safety, but also for preservation of the durability of the structure, because cracking damage in large cooling towers in general cause extremely high cost of maintenance and repair. The paper demonstrates numerically the damage process in large cooling towers (Kr$\ddot{a}$tzig et al. 2001), and describes some basics of the numerical finite element approach for damage propagation modelling of shell structure. A prototype is analysed to trace the progressive damage process, whereby the changes in the dynamical behaviour of the structure, as mirrored in its natural frequencies and the corresponding mode shapes, are presented and discussed. Finally, the example shows that such damage processes develop progressively over the life-time of the shell structure.

• Earthquakes and Structures
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• 제7권5호
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• pp.609-626
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• 2014

The capabilities of a high-resolution Digital Image Correlation (DIC) system are presented within the context of deformation measurements of full-scale concrete columns tested under reversed cyclic loading. The system was developed to have very high-resolution such that material strains on the order of the cracking stain of concrete could be measured on the surface of full-scale structural members. The high-resolution DIC system allows the measurement of a wide range of deformations and strains that could only be inferred or assumed previously. The DIC system is able to resolve the full profiles of member curvatures, rotations, plasticity spread, shear deformations, and bar-slip induced rotations. The system allows for automatic and objective measurement of crack widths and other damage indices that are indicative of cumulated damage and required repair time and cost. DIC damage measures contrast prevailing proxy damage indices based on member force-deformation data and subjective damage measures obtained using visual inspection. Data derived from high-resolution DIC systems is shown to be of great use in advancing the state of behavioral knowledge, calibrating behavioral and analytical models, and improving simulation accuracy.

• 한국신뢰성학회지:신뢰성응용연구
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• 제17권2호
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• pp.159-167
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• 2017

Purpose: The purpose of this research is to study research trend in the field of warranty and maintenance policy of second-hand products. Methods: To this end, we consider research articles, which deal with warranty and maintenance of the second-hand products, published on journals during the past 20 years and classify them by taxonomy scheme proposed by Shafiee and Chukova (2013). The taxonomy scheme consists of three maintenance models in warranty for second-hand product. In each models, we analyze proposed maintenance and warranty policies with respect to types of upgrade models, types of preventive maintenances, decision variables and decision criteria model. Results: We obtain the scheme of maintenance and warranty of the second-hand products and define cost related to warranty and maintenance of the second-hand item. Also, we summarize the characteristics of maintenance and warranty policies in each classified model. Conclusion: There have been several research reviews on maintenance and warranty polity of new products. This research surveys researches of authors during the past 20 years and classifies, summarizes and compares proposed maintenance and warranty policies of the second-hand products. This research provides useful information to researchers who are interested in maintenance and warranty of the second-hand products.

• Corrosion Science and Technology
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• 제16권2호
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• pp.85-89
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• 2017

One of the most challenging issues in the oil and gas industry is corrosion assessment and management in subsea structures or equipment. At present, almost all steel pipelines are sensitive to corrosion in harsh working environments, particularly in salty water and sulphur ingress media. Nowadays, the most commonly practiced solution for a damaged steel pipe is to entirely remove the pipe, to remove only a localized damaged section and then replace it with a new one, or to cover it with a steel patch through welding, respectively. Numerous literatures have shown that fiber-reinforced polymer-based composites can be effectively used for steel pipe repairs. Considerable research has also been carried out on the repair of corroded and gouged pipes incorporated with hybrid natural fiber-reinforced composite wraps. Currently, further research in the field should focus on enhanced use of the lesser and highly explored hybrid-biocomposite material for the development in corrosion prevention. A hybrid-biocomposite material from renewable resource based derivatives is cost-effective, abundantly available, biodegradable, and an environmentally benign alternative for corrosion prevention. The aim of this article is to provide a comprehensive review and to bridge the gap by developing a new hybrid-biocomposite with superhydrophobic surfaces.

• 한국신뢰성학회지:신뢰성응용연구
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• 제17권3호
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• pp.246-255
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• 2017

Purpose: This study proposes the optimal PM (preventive maintenance) policy of leased equipment for lessee's decision-making using two types of reliability condition. Methods: We consider reliability threshold based PM model. Equipment reliability is estimated and used as condition variable. The effect of repair for maintenance is imperfect and represented by age reduction factor. Results: We provide two PM policies. Policy 1 is focused on minimized total cost. This policy guarantees reliability threshold until last maintenance action. Policy 2 focus on maintaining reliability threshold during leased period. The proposed approach provides optimal reliability threshold under number of PM. Through result, we finally construct decision-making process for lessee using reliability threshold and end of reliability. Conclusion: This study provides two PM policy for lessee's decision-making. Through numerical example, we get a result of optimal reliability threshold, number of PM, optimum alternative under lessee's reliability condition.

• Steel and Composite Structures
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• 제14권6호
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• pp.547-569
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• 2013

In recent years there has been increasing international interest about designing structures that cost less to repair after they have been subjected to strong earthquakes. Considering this interest, an innovative repairable fuse device has been developed for dissipative beam-to-column connections in moment-resisting composite steel and concrete frames. The seismic performance of the device was assessed through an extensive experimental program comprising ten cyclic and two monotonic tests. These tests were conducted on a single beam-to-column specimen with different fuse devices for each test. The devices varied in terms of the chosen geometric and mechanical parameters. The tests showed that the devices were able to concentrate plasticity and to dissipate large amounts of energy through non-linear behavior. Numerical models were developed with Abaqus and simplified design models are also proposed.

• 한국가스학회지
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• 제11권3호
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• pp.56-63
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• 2007

오늘날 고객의 요구는 보다 더 다양해지고 있고, 시장 환경이 급속히 변화함에 따라 기업의 모든 활동은 고객중심으로 이루어지고 있다. 최근 제품 및 서비스의 품질 향상을 위해 변화혁신 활동을 추진한 기업이 늘어나고 있는 실정이다. 본 연구는 도시가스 공급시설을 효율적으로 보수하기 위하여 6시그마 기법을 이용하여 공급시설 건전성에 영향을 주는 핵심인자를 도출하였으며, Risk 인자는 정량적인 평가를 통하여 시그마 값을 산출하였고, 근본원인 및 해결안을 도출, 새로운 프로세스를 적용하여 통계적 공정관리를 실행하였다. 도시가스 공급시설의 안전관리는 위험을 정량화하여 통계적인 공정관리를 통하여 산포를 줄이고, 품질관리 비용을 제거해서 효율적인 경영관리가 가능하며, 6시그마 이용 기법의 정착과 효율적인 운용의 확산을 통해 과학적인 안전관리가 가능할 것으로 기대된다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 Asia Navigation Conference
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• pp.129-133
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• 2006

In China, the traditional method of artificial and periodical cruise is still adopted for the AtoN management, which has brought many disadvantages to the work of the AtoN management, such as non real-time, fallibility, and low efficiency However, with the rapid development of AIS technique, now AIS equipments have been widely installed on ships, and on the other hand China Maritime Safety Administration (abr. China MSA) is carrying out the scheme of AIS base station network in china, based on which the digital AtoN will develop in the future. According to what have been analyzed above, this paper puts forward a design of AtoN wireless surveillance system based on AIS. The system consists of AIS on AtoN, AIS base station and AtoN management center. It can provide such functions as the information gathering, managing of AtoN and the service of navigation assistance. This paper gives the whole design including the work theory, the hardware structure and the software scheme of the system, and finally gives the simulation software of the AtoN management center. The AtoN wireless surveillance system brought forward by this paper will be more efficient with less repair cost and less work of the supervisors. It will bring revolutionary progress in the navigation aids system in China.