• Journal of Medicine and Life Science
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• 제19권3호
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• pp.116-120
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• 2022

Objective: To estimate the efficacy of sequential treatment of bladder endometriosis (BE) of the vesicoureteric junction using transurethral resection (TUR) and hormonal therapy. Design: Case report. Setting: Private multispecialty hospital. Patient: A multiparous woman presented with perimenstrual lower urinary tract symptoms, cyclic chronic pelvic pain, and left loin pain. Intervention[s]: Ultrasonography revealed marked left renal dilatation. Computed tomography confirmed the presence of a bladder mass. A diagnostic cystoscopy revealed compression of the left vesicoureteral junction. Complete TUR BE with release of chocolate material during resection, followed by ureteric double J stent insertion for 3 months, was performed. Histopathology confirmed the diagnosis of BE, followed by adjuvant hormonal therapy (dienogest) for 3 months. Follow-up for about 2 years revealed complete relief of the symptoms without any recurrence. Main Outcome Measure[s]. Success and recurrence rates of sequential TUR and hormonal therapy of BE of the vesicoureteric junction. Result[s]. TUR BE followed by adjuvant hormonal therapy was very effective in eradicating BE of the vesicoureteric junction in a safe manner without recurrence on follow-up for 2 years. Conclusion[s]. BE of the vesicoureteric junction can be properly treated by sequential TUR and hormonal therapy without recurrence over a 2-year follow-up.

• 한국전자거래학회지
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• 제23권1호
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• pp.47-63
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• 2018

무형자산의 가치평가에 많이 사용되고 있는 수익접근법과 시장접근법의 특성을 모두 가지고 있는 로열티공제법을 사용하여 지식재산권의 경제적 가치를 평가할 때, 로열티공제법의 중요한 투입변수인 로열티율을 객관적으로 산정하는 수리적 모형을 제시한다. 이를 위하여 미국의 특허침해 손해배상액을 로열티율로 산정한 판례를 참고로 하여 로열티율을 종속변수로, 당해 특허권의 특허지표를 독립변수로 하여 로열티율 산정 회귀모형을 적용한다. 또한 미국의 당사자계재심(Inter-Partes Review)판례를 참고로 하여 특허무효거절 결과를 종속변수로 하고 당해 특허권의 특허지표를 독립변수로 하여 로지스틱회귀 모형을 적합시킨다. 최종 로열티율은 위의 로열티율 산정 회귀모형에서 산출된 로열티율과 로지스틱회귀모형에서 산출된 특허무효거절 확률을 결합하여 산정한다. 마지막으로, 본 논문에서 구축된 모형에 의해 산정된 로열티율과 기준 방식에 의해 산정된 로열티율을 비교하여 제안된 모형의 객관성과 신뢰성을 분석한다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2023년도 춘계학술대회
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• pp.105-105
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• 2023

Heavy metals, including lead (Pb) toxicity, are increasing in soil and are considered toxic in small amounts. Pb contamination is mainly caused by industrialization - smelting, mining. Agricultural practices - sewage sludge, pests and urban practices - lead paint. It can seriously damage and threaten crop growth. Pb can adversely affect plant growth and development by affecting the photosystem, cell membrane integrity, and excessive production of reactive oxygen species (ROS) such as hydrogen peroxide (H₂O₂)andsuperoxide(O₂.-). NO is produced via enzymatic and non-enzymatic antioxidants to scavenge ROS and lipid peroxidation substrates in terms of protecting cells from oxidative damage. Thus, NO improves ion homeostasis and confers resistance to metal stress. Our results here suggest that exogenous NO may aid in better growth under lead stress. These enhancements may be aided by NO's ability in sensing, signaling and stress tolerance in plants under heavy metal stress in combination with lead stress. Our results show that GSNO has a positive effect on soybean seedling growth in response to axillary pressure and that NO supplementation helps to reduce chlorophyll maturation and relative water content in leaves and roots following strong burst under lead stress. GSNO supplementation (200 µM and 100 µM) reduced compaction and approximated oxidative damage of MDA, proline and H₂O₂. Under plant tension, a distorted appearance was found in the relief of oxidative damage by ROS scavenging by GSNO application. In summary, modulation of these NO, PCS and prolongation of metal past reversing GSNO application confirms the detoxification of ROS induced by toxic metal rates in soybean. In summary, these NO, PCS and metal traditionally sustained rates of reverse GSNO application confirm the detoxification of ROS induced by toxic metal rates in soybean.

• Journal of Korean Neurosurgical Society
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• 제67권3호
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• pp.354-363
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• 2024

Objective : This study aims to determine the optimal dose of recombinant-human bone morphogenic protein-2 (rhBMP-2) for successful bone fusion in minimally invasive lateral lumbar interbody fusion (MIS LLIF). Previous studies show that rhBMP is an effective alternative to autologous iliac crest bone graft, but the optimal dose remains uncertain. The study analyzes the fusion rates associated with different rhBMP doses to provide a recommendation for the optimal dose in MIS LLIF. Methods : Ninety-three patients underwent MIS LLIF using demineralized bone matrix (DBM) or a mixture of rhBMP-2 and DBM as fusion material. The group was divided into the following three groups according to the rhBMP-2 usage : group A, only DBM was used (n=27); group B, 1 mg of rhBMP-2 per 5 mL of DBM paste (n=41); and group C, 2 mg of rhBMP-2 per 5 mL of DBM paste (n=25). Demographic data, clinical outcomes, postoperative complication and fusion were assessed. Results : At 12 months post-surgery, the overall fusion rate was 92.3% according to Bridwell fusion grading system. Groups B and C, who received rhBMP-2, had significantly higher fusion rates than group A, who received only DBM. However, there was no significant increase in fusion rate when the rhBMP-2 dosage was increased from group B to group C. The groups B and C showed significant improvement in back pain and Oswestry disability index compared to the group A. The incidence of screw loosening was decreased in groups B and C, but there was no significant difference in the occurrence of other complications. Conclusion : Usage of rhBMP-2 in LLIF surgery leads to early and increased final fusion rates, which can result in faster pain relief and return to daily activities for patients. The benefits of using rhBMP-2 were not significantly different between the groups that received 1 mg/5 mL and 2 mg/5 mL of rhBMP-2. Therefore, it is recommended to use 1 mg of rhBMP-2 with 5 mL of DBM, taking both economic and clinical aspects into consideration.

• KDI Journal of Economic Policy
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• 제35권3호
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• pp.39-63
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• 2013

본 연구에서는 국내 최초로 풍수해보험에 대한 포괄적인 설문자료를 바탕으로 보험가입자들의 역선택 존재 여부에 대한 실증분석을 수행하였다. 풍수해보험은 경제주체들이 개별적으로 풍수해위험에 대처하는 경우보다 위험분산을 통해 더 높은 효용을 누릴 수 있도록 해주는 수단이다. 그러나 정부개입 없이는 보험시장의 형성이 어려울 뿐더러 여타 보험시장과 마찬가지로 역선택 문제가 존재할 가능성이 크다. 즉, 상대적으로 피해 발생 확률이 높은 가입자들만이 스스로 풍수해보험에 가입하는 결과가 초래되어 시장실패가 나타나게 된다. 본 연구의 실증분석 결과, 소유주의 풍수해에 대한 과거 경험과 위험도로 나타난 소유시설 주변의 위험요인이 풍수해보험 가입에 통계적으로 유의한 정(+)의 영향을 주는 것으로 나타났다. 이는 현행과 같은 정부의 보험료 지원방식이 풍수해보험시장의 역선택 문제를 야기하고 있어 효율성 측면에서 개선될 필요가 있다는 점을 시사한다.

• Perspectives in Nursing Science
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• 제12권1호
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• pp.14-22
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• 2015

Purpose: Forests have positive effects on health due to phytoncide, thus increasing physical activity and stress relief. However, research has not been conducted on the daily health benefits of existing forests. Therefore, this study attempts to compare the health status and behaviors of residents in urban and forested areas. Methods: This cross-sectional study used anthropometric measures, blood tests, heart rate variability, depression, stress, and health behavior self-reports for adults between 35 and 79 years from two regions. Results: Adults living in a forested region had better health consequences-including lower prevalence of osteoarthritis (6.4%) and mean bone mineral density (-0.84) -than those in an urban region (osteoarthritis: 13.7%; bone mineral density: -1.55). The percentage of 'physically active' participants (measured in MET-minutes) differed significantly different between the forested (49.1%) and urban (7.3%) areas. However, health behaviors such as smoking, alcohol consumption, and regular heath check-up rates were worse among residents from the forested, than the urban area. Conclusion: We concluded that more proactive forest therapy programs are needed to prove the health differences.

• 대한지리학회지
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• 제44권3호
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• pp.224-239
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• 2009

본 연구는 오대천 상 하류의 하천 지형 특성을 분석하고, 오대천의 하천 및 하안단구 지형 형성과정에 대해 검토하였다. 오대천은 상류 화강암 지역보다 하류 퇴적암 지역에서 풍화 침식에 대한 저항력이 크기 때문에, 상류보다 하류 유역분지에서 해발고도가 높고, 기복량은 크며, 경사도가 높게 나타난다. 또한 상류보다 하류에서 평균 하곡 폭이 1/3 정도로 좁고, 평균 하도 폭도 더 좁은 것으로 측정되었다. OSL 연대 측정 결과 하안단구 1면의 형성시기는 최종 빙기 최성기인 MIS 2기말의 기온 상승기이며, 하안단구 2면은 최종 빙기 내의 아간빙기에 해당되는 MIS 3기 중반으로 측정되었다. 이를 토대로 하안단구 2면 형성 이후 현재까지 오대천의 평균 하각률은 상류 화강암 지역에서 0.205m/ka 하류 퇴적암 지역에서 0.269m/ka로 계산되었다.

• The Korean Journal of Pain
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• 제20권2호
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• pp.240-245
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• 2007

It is important to treat cancer-related pain in cancer patients to ensure the life quality of the patient, as well as to improve their life span. It has been estimated that at least 5% of cancer patients have pain refractory to medical treatment. Therefore, the need for epidural or intrathecal analgesia with opioids and local anesthetics is indicated if systemic treatment has failed. Intrathecal catheter placement and implantation of the injection port for administration of opioids and local anesthetics may improve pain relief in patients who are unresponsive to epidural routes. Although intrathecal implantation has several complications, similar infection rates have been reported between intrathecal and epidural administration. In addition, intrathecal administration showed better outcomes, including improved pain control, lowered daily doses, and an improvement in the level of drowsiness experienced when compared to epidural administration. We report here a case in which a terminal cancer patient was treated using an intrathecal catheter and subcutaneous port. The patient had cancer-related pain that could not be controlled by epidural opioid administration. Based on the results presented here, we suggest that intrathecal implantation is a feasible long term pain management method for intractable cancer pain patients.

• 생물정신의학
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• 제26권1호
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• pp.1-7
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• 2019

Since non-cardiac chest discomfort (NCCD) can result in substantial healthcare burden and lower quality of life, interventions such as cognitive behavioral therapy (CBT) have been investigated for the relief of NCCD. In this review, we aimed to summarize the evidence on the efficacy of the CBT for the treatment of NCCD while introducing a newly-developed computerized CBT program for NCCD. Studies applying CBT to individuals with NCCD were searched for from both English and Korean electronic databases. Among 37 studies, 11 randomized controlled trials, 4 case-control studies, 1 case series, and 2 review articles were eligible for this review. Efficacy of conventional CBT for NCCD was shown in a series of studies as most of them reported improved symptom severity of NCCD or NCCD-related anxiety. However, a substantial variability existed among these studies in participants, treatment procedures and durations. High attrition rates were also reported in these studies on conventional CBT. Computerized CBT could be an alternative to the conventional CBT as it can be standardized and more easily accessible, but it was only reported in one previous study. In addition to the literature review, we presented a newly-developed computerized CBT program for NCCD which may overcome some of the limitations of conventional CBT. A computerized CBT could be an alternative treatment of NCCD, however, need further studies on its usefulness.

• 한국학교보건학회지
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• 제31권3호
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• pp.186-195
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• 2018

Purpose: This study was performed to investigate the dietary behaviors and stress-related factors among male and female college students. Methods: A total of 405 college students (male-195, female-210) were recruited, of whom a questionnaire-based survey was conducted. The study investigated the general characteristics, health-related factors, dietary behaviors, and stress-related factors of the respondents. Results: The body mass index was significantly higher in males. The rates of underweight and overweight were significantly different between male and female respondents. The scores for workout frequency, health concerns and health condition were significantly higher in males, while the score for watching TV & playing computer games was significantly higher in females. The scores for meal regularity, frequency of breakfast consumption, and smoking were significantly higher in males. Eating problems showed a significant difference between males and females. The biggest source of stress was social factors, followed by college study and individual factors and the most experienced stress-induced symptom was anxiety, followed by headache and stomachache. The most popular way to overcome stress was taking a rest, followed by drinking & smoking and outdoor activity. The most preferred food under stressful conditions were alcohol or beverages, followed by hot & spicy food and sweet food, which showed a significant difference between males and females. Conclusion: These results indicate that stress affects dietary behaviors, drinking, smoking, and health status. Stress not only changes dietary behaviors, but is also related to health status. Therefore, it is necessary to develop appropriate programs for emotional stability and stress relief targeting college students which provide continuous nutrition education focused on desirable dietary behaviors and nutritional aspects.