• 한국경영과학회지
• /
• 제28권1호
• /
• pp.1-10
• /
• 2003

A recent trend In flexible manufacturing systems (FMS) Is to utilize the Identical versatile machines with fast tool delivery devices. Unlike a conventional FMS where parts are fed to the machines with the required tools, tools are acquired from other machines using a tool delivery system and parts can be finished on the same machine In these FMS. Therefore it Is more important problem 4o plan tool flow using tool delivery system In these FMS rather than part flow In conventional FMS. According to the existing study, In FMS 20∼30 percent of the total management cost Is the cost related with tools and It Is possible to reduce the tool Inventory by 40 percent using efficient tool allocation. In this study, In FMS under dynamic tool allocation strategy, a new method of part release considering tool flow at the stage of part release Is proposed. In order to prove the efficiency of the proposed part release It is compared with other part release through simulation experiments. Performance measures in these experiments are the throughput and the number of tardy parts.

• Journal of Pharmaceutical Investigation
• /
• 제40권5호
• /
• pp.297-304
• /
• 2010

The present work focuses on preparation of olanzapine, orally dispersing tablets by direct compression method. Effect of super disintegrant crospovidone, disintegration time, drug content on in vitro release has been studied. A factorial design was employed in formulating a prompt dispersible tablet. The selected independent variables crospovidone and fmelt showed significant effect on dependent variables i.e. disintegration time and percent drug dissolved. Disintegration time and percent drug dissolved decreased with increase in the level of crospovidone. The similarity factor $f_2$ was found to be 97.48 for the developed formulation indicating the release was similar to that of the marketed formulation. Pharmacokinetics of olanzapine after single-dose oral administration of orally disintegrating tablet in normal volunteers were evaluated and the results showed that PK parameters (Cmax, Tmax, AUC) of the designed ODT matrix were similar to those of commercial product, Zyprexa Zydis$^{(R)}$ as a reference.

• Journal of Pharmaceutical Investigation
• /
• 제35권3호
• /
• pp.151-155
• /
• 2005

A drug delivery system(DDS) for practically insoluble meloxicam was developed and evaluated by dissolution study. A novel DDS is two layered system, where the first layer is consisted of gas-forming agent for an immediate release and the second layer is composed of metolose SR(HPMC) for sustained release. This bilayered tablets were manufactured by using manual single punch machine. The results of dissolution study showed an initial burst release followed by sustained release for the experimental period time. From a pharmaceutical point of view, the designed DDS for meloxicam would be informative system in terms of poorly soluble analgesic medicines.

• 한국시뮬레이션학회:학술대회논문집
• /
• 한국시뮬레이션학회 1999년도 춘계학술대회 논문집
• /
• pp.194-198
• /
• 1999

Order Review/Release(ORR) 시스템은 생산계획 시스템과 작업현장간의 연결고리로서, 작업현장으로의 작업투입을 조절하여 작업현장에서의 체류시간과 공정중재고, 리드타임의 변동을 줄여주는 역할을 한다. 그러나, 지금까지의 ORR에 관한 연구들은 ORR의 유효성에 관하여 명확한 결론을 내지 못하고 있다. 일부는 ORR이 작업의 전체 리드타임을 증가시키는 악영향이 있음을 주장하고, 일부는 ORR을 도입함으로써 작업현장에서의 리드타임과 공정중재고가 줄어들고, 안정화될 수 있다고 주장한다. 본 연구는 어떠한 환경에서 Order Release 정책을 도입하는 것이 시스템의 성능향상에 기여할 수 있는 지 확인하는 것을 목적으로 하고, 가상의 Job Shop을 대상으로 시뮬레이션을 수행하였다. 작업장가동률 수준과 생산계획 단계에서의 계획오더 이송간격을 환경분수로 설정하고, 작업현장의 부하를 고려하여 작업투입을 통제하는 다섯 가지 Order Release 정책과 세 가지 우선순위 규칙을 적용하여 실험하였으며, 리드타임, 납기, 공정중재고 등과 관련된 8가지 척도에 대해 각 정책을 평가하였다. 그리고, 계획시스템의 부하평준화 기능이 존재할 때, Order Release 정책의 도입으로 인한 효과가 더 크다는 기존의 연구결과를 검증하기 위해, 부하평준화를 적용하였을 때 Order Release를 통제하지 않는 정책과 통제하는 정책간의 성능향상 차이가 있는지를 확인하는 실험을 수행하였다. 실험결과, ORR 보다는 우선순위규칙이 시스템의 성능을 결정하는 주요 통제정책으로 밝혀졌다. 그러나, 생산계획시스템에서 1주 간격으로 계획오더를 이송할 때는 Order Release 방법을 적용하여 작업현장에서의 평균 리드타임과 리드타임의 변동, 공정중재고가 줄어드는 결과를 보였고, 가동률 수준이 높을수록 ORR 방법간의 차이가 크게 나타났다. 그리고 부하평준화 기능은 Order Release 정책의 유효성에 별 영향을 주지 않는 것으로 나타났다. 결론적으로, Order Release 방법은 우선순위규칙간의 성능차이를 줄이거나, 대체할 수 통제 기법이라기보다는 우선순위규칙을 보완하여 공정중재고와 작업현장에서의 리드타임, 리드타임의 편차를 줄여주는 역할을 한다고 볼 수 있다. 그리고, 계획시스템이 존재하여 계획오더가 일정기간간격으로 이송되는 환경에서 특히 유용하다는 결론을 얻었다.

• 국제학술발표논문집
• /
• The 2th International Conference on Construction Engineering and Project Management
• /
• pp.61-68
• /
• 2007

There has been a lot of research on and release of commercial systems that enable evaluation and visualization of construction methods. These have enabled the selection of good construction plans. However, the process in which engineers build 3D geometry, formulate a schedule and eventually synchronize them is still a time-consuming process. Changing any aspect of the geometry or the schedule and re-linking them is also time-consuming. Therefore, the engineers may compromise on getting the best solution. This paper describes a technique to automate the generation of multiple sets of schedules, quantity takeoffs and 4D visualization from a single 3D model.

• Nuclear Engineering and Technology
• /
• 제52권10호
• /
• pp.2402-2409
• /
• 2020

Analytical criteria for the onset of fuel fragmentation and Burst Fission Gas Release in fuel rods with ballooned claddings are formulated. On that basis, the GRSW-A model integrated with a fuel behaviour code is updated. After modification, the updated code is successfully applied to simulation of the Halden LOCA test IFA-650.12. Specifically, the calculation with Burst Fission Gas Release during the test resulted in prediction of cladding failure, whereas it could not be predicted at the test planning, before new models were implemented. A good agreement of the current model with experimental data for transient Fission Gas Release in the tests IFA-650.12 and IFA-650.14 is shown, as well.

• Environmental Analysis Health and Toxicology
• /
• 제12권1_2호
• /
• pp.13-19
• /
• 1997

서론 : 1. 유해물질 배출목록 제도의 역사 미국은 1986년 인도 보팔 참사에 대한 후속조치로 긴급계획 및 지역 공동사회의 알 권리법(the Emergency Planning and Community Right-to-know Act : EPCRA)을 통과시켰다. 유해물질 사고 예방과 일어날 수 있는 긴급 상황에 대한 계획이다. 이 법의 일부분인 유해물질 배출목록은 환경에 매일 유출되는 유해물질을 다루고 있다. (생략)

• 한국시뮬레이션학회논문지
• /
• 제8권4호
• /
• pp.73-87
• /
• 1999

Order Review/Release (ORR) System is the linkage between planning system and actual production. Reduction of the waiting time on the machines, work in process and lead time variation may be achieved by adopting ORR strategies. But researchers on the ORR do not agree on the effectiveness of ORR. Some say that the overall system flow time may be increased if ORR is adopted, but others say that ORR can reduce work in process, flow time and variation of flow time. The objective of this research is to clarify under what environments order release strategy is effective. Simulation study was conducted in a hypothetical job shop. The experimental results show that dispatching rule is much more important than ORR is in controlling the shop floor. But the results indicate that ORR can reduce mean shop flow time, average work in process and variation of shop flow time under such environments where utilization level is high and planned order is weekly released to the order pool. And the results also show that the effect of plan smoothing on the ORR is insignificant, which is inconsistent with the results of the previous researches.

• Nuclear Engineering and Technology
• /
• 제51권4호
• /
• pp.1098-1108
• /
• 2019

Korea's first commercial nuclear power plant at Kori site was permanently shut down in 2017 and is currently in transition stage. Preparatory activities for decommissioning such as historical site assessment, characterization, and dismantling design are being actively carried out for successful D&D (Dismantling and Decontamination) at Kori site. The ultimate goal of decommissioning will be to ensure the safety of workers and residents that may arise during the decommissioning of nuclear facilities and, thereby finally returning the site to its original status in accordance with the release criteria. Upon completion of decommissioning, the resident's safety at a site released will be assessed from the evaluation of dose caused by radionuclides expected to be present or detected at the site. Although the U.S. commercial nuclear power plants with decommissioning experience use different site release criteria, most of them are 0.25 mSv/y. In Korea, both the unrestricted and restricted release criteria have been set to 0.1 mSv/y by the Nuclear Safety and Security Commission. However, since the dose is difficult to measure, measurable concentration guideline levels for residual radionuclides that result in dose equivalent to the site release criteria should be derived. For this derivation, site reuse scenario, selection of potential radionuclides, and systematic methodology should be developed in planning stage of Kori site decommissioning. In this paper, for calculation of a preliminary site-specific Derived Concentration Guideline Levels (DCGLs) for the Nuclear Power Plant site, a novel approach has been developed which can fully reflect practical reuse plans of the Kori site by taking into account multiple site reuse scenarios sequentially, thereby striking a remarkable distinction with conventional approaches which considers only a single site scenario.

• International Journal of Naval Architecture and Ocean Engineering
• /
• 제11권1호
• /
• pp.353-363
• /
• 2019

This paper presents a comprehensive simulation and assessment of gas dispersion above sea from a subsea release using a Computational Fluid Dynamics (CFD) approach. A 3D CFD model is established to evaluate the behavior of flammable gas above sea, and a jack-up drilling platform is included to illustrate the effect of flammable gas cloud on surface vessels. The simulations include a matrix of scenarios for different surface release rates, distances between surface gas pool and offshore platform, and wind speeds. Based on the established model, the development process of flammable gas cloud above sea is predicted, and the dangerous area generated on offshore platform is assessed. Additionally, the effect of some critical factors on flammable gas dispersion behavior is analyzed. The simulations produce some useful outputs including the detailed parameters of flammable gas cloud and the dangerous area on offshore platform, which are expected to give an educational reference for conducting a prior risk assessment and contingency planning.