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Simultaneous Analysis of Mycotoxins and Risk Assessment in Seeds using LC-MS/MS (LC-MS/MS를 이용한 종자류 생약의 곰팡이독소 동시분석 및 위해도 평가)

  • Choi, Eun Jung;Park, Young Ae;Choi, Su Jeong;Jung, Sam Ju;Park, Youn Sun;Hwang, In Sook;Yu, In Sil;Shin, Gi Young
    • Korean Journal of Pharmacognosy
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    • v.51 no.4
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    • pp.270-277
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    • 2020
  • This study analyzed mycotoxins, aflatoxin B1, B2, G1, G2, fumonisin B1, B2, ochratoxin A and zearalenone, using LC-MS/MS and conducted risk assessment on 54 samples of seeds distributed in SeoulYangnyeongsi and the management status of extramural herbal dispensary facility. The matched calibration showed a good linearity as observed in 6 concentration levels(r2>0.999) as a result of method validation applied with Arecae semen. Limits of detection(LOD) and quantification(LOQ) were in the range of 0.02-0.11 ㎍/kg and 0.08-0.34 ㎍/kg, respectively. Recoveries also estimated, ranging from 65.1-99.7% with relative standard deviation(RSD) 0.5-6.3%. As a result of the method on 54 samples, mycotoxins were detected in 16 samples. Among them, two Thujae semen showed a degree of concentration that exceeded the aflatoxin specification. In the risk assessment, the human exposure safety standard values were calculated as ADI(Acceptable Daily Intake) for aflatoxin B1, fumonisin and zearalenone. Ochratoxin A was calculated as PTWI(Provisional Tolerable Weekly Intake). The MOE(Margine of Exposure) of aflatoxin B1 was in the range of 40.36-3536.88. And no items exceeded 100% in %TDI(Tolerable Daily Intake) and %TWI(Tolerable Weekly Intake) of fumonisin, zearalenone and ochratoxin A.

STAR FORMATION ACTIVITY OF GALAXIES UNDERGOING RAM PRESSURE STRIPPING IN THE VIRGO CLUSTER

  • Mun, Jae Yeon;Hwang, Ho Seong;Lee, Myung Gyoon;Chung, Aeree;Yoon, Hyein;Lee, Jong Chul
    • Journal of The Korean Astronomical Society
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    • v.54 no.1
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    • pp.17-35
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    • 2021
  • We study galaxies undergoing ram pressure stripping in the Virgo cluster to examine whether we can identify any discernible trend in their star formation activity. We first use 48 galaxies undergoing different stages of stripping based on H i morphology, H i deficiency, and relative extent to the stellar disk, from the VIVA survey. We then employ a new scheme for galaxy classification which combines H i mass fractions and locations in projected phase space, resulting in a new sample of 365 galaxies. We utilize a variety of star formation tracers, which include g - r, WISE [3.4]-[12] colors, and starburstiness that are defined by stellar mass and star formation rates to compare the star formation activity of galaxies at different stripping stages. We find no clear evidence for enhancement in the integrated star formation activity of galaxies undergoing early to active stripping. We are instead able to capture the overall quenching of star formation activity with increasing degree of ram pressure stripping, in agreement with previous studies. Our results suggest that if there is any ram pressure stripping induced enhancement, it is at best locally modest, and galaxies undergoing enhancement make up a small fraction of the total sample. Our results also indicate that it is possible to trace galaxies at different stages of stripping with the combination of H i gas content and location in projected phase space, which can be extended to other galaxy clusters that lack high-resolution H i imaging.

Qualitative attributes of meat from Teramana goat kids, an Italian native breed of the Abruzzo region

  • Ianni, Andrea;Bennato, Francesca;Martino, Camillo;Luca, Alessio Di;Martino, Giuseppe
    • Animal Bioscience
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    • v.35 no.7
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    • pp.1091-1099
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    • 2022
  • Objective: The aim of this work was the characterization of the qualitative aspects of meat obtained from Teramana goats, an Italian indigenous breed of the Abruzzo region. Specifically, the study included a comparison with meat samples deriving from Saanen goat kids reared in the same environment and applying the same feeding protocol. Methods: Upon reaching about 7 months of age the animals were slaughtered and samples of muscle tissue were collected to be analyzed. Specifically, meat samples were subjected to evaluations of the physical parameters, including color and the meat ability to retain water, in addition to chemical evaluations that were focused to the determination of the total lipids amount, fatty acids composition, lipid oxidation, and volatile profile. Results: The meat samples obtained from the indigenous breed showed a less intense reddish color and no significant variations for the muscle tissue tendency to retain water, both regarding fresh and cooked meat. Several differences were instead observed in the fatty acid profile. The Teramana samples were richer in saturated fatty acids (p<0.01) and interestingly showed higher concentrations of rumenic acid (p<0.05), a conjugate of linoleic acid that has been associated with important health benefits for the consumers. Another important finding for these meat samples was the marked resistance to oxidative events, as evidenced by the thiobarbituric acid reactive substances-test (p<0.05) and by the characterization of the volatile profile that highlighted a strong reduction in the relative percentage of hexanal (p<0.05), commonly associated to lipid oxidation and the development of unpleasant aromatic notes. Conclusion: The collected data, therefore appeared useful for the valorization of the food product derived from the Teramana goat, although no sensory information has been collected to define the degree of acceptability by the consumers.

Transient simulation and experiment validation on the opening and closing process of a ball valve

  • Han, Yong;Zhou, Ling;Bai, Ling;Xue, Peng;Lv, Wanning;Shi, Weidong;Huang, Gaoyang
    • Nuclear Engineering and Technology
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    • v.54 no.5
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    • pp.1674-1685
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    • 2022
  • The ball valve is an important device in the pipeline transportation system of nuclear power plants. Its operational stability and safety directly affect the normal working of nuclear power plants. In this study, the transient numerical simulation of the opening and closing process of a ball valve was conducted on the basis of the flow interruption capability experiment of the ball valve by using the moving mesh method and inlet and outlet variable boundary conditions. The flow rate and pressure difference with time of the opening and closing process of the ball valve were studied. The internal flow characteristics of the ball valve under different relative openings were analyzed in conjunction with the typical back-step flow structure. Results show that the transient numerical results agree well with the experimental results. The internal flow characteristics of the ball valve are similar at the same opening during opening and closing process. At small opening, the spool and outlet channels easily form a back-step flow structure. The disappearance and generation of backflow vortices during opening and closing occur at 85% opening and 75% opening, respectively. With the decrease in opening degree, the difference in vortex core area in the flow channel of the ball valve spool in the opening and closing process gradually appears. The research results provide some reference value for the design and optimization of ball valves.

Importance Analysis of Image Evaluation Items that Recognize Places (장소를 인식하는 이미지 평가항목에 대한 중요도 분석)

  • Lee, Lim-Jung;Kim, Kwang-Soo;Kim, Min-Seok
    • Journal of the Korean Institute of Rural Architecture
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    • v.24 no.3
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    • pp.1-11
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    • 2022
  • Purpose: This place, which is currently becoming an issue due to historical preservation and landscape protection, is also a place where urban residents around Taereung actually visit often. Thus, this study aims to analyze the importance of the evaluating factors in creating a relatable image of the city. Methods: Evaluation items were selected by reviewing related books and research literatures and reassessing the reviewed items through an expert group interview (FGI). For the selected evaluation items, the relative importance of the evaluation items for the place image was analyzed by applying the hierarchical analysis technique (AHP) to each user group. Result: A place becomes a memory in people's experiences and time, and it has the image and identity of the region where those experiences and memories are found again as a space called "place". The method of analyzing the importance of evaluation items between place images used in this study quantified the factors recognized as abstract images and identified the degree of influence between elements, but has limitation in that it targeted specific places. However, the analysis method on the place image recognition suggests the use of itemized variables for characteristics between place images, so future research on the identity of other place images can be conducted together. Also, the evaluation method of the image that recognizes the place has an objective meaning in that it can measure the image of the place quantitatively. In the future, it can be applied in creating an image forming factor or urban identity for place recognition in many regions

The Economic Security System in the Conditions of the Powers Transformation

  • Arefieva, Olena;Tulchynska, Svitlana;Popelo, Olha;Arefiev, Serhii;Tkachenko, Tetiana
    • International Journal of Computer Science & Network Security
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    • v.21 no.7
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    • pp.35-42
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    • 2021
  • In the article, the authors investigate the economic security system in the conditions of the powers transformation. It is substantiated that economic security acts as a certain system that includes components and at the same time acts as a subsystem of the highest order. It is determined that the economic security system of regions acting as a system has its subsystems, which include: production, financial, environmental, innovation, investment and social subsystems. The parameters of the economic security system include relative economic independence, economic stability and self-development of economic systems, and it is proved that an important feature of economic security in addition to its systemic nature is multi-vector. It is substantiated that the monitoring of ensuring the economic security system of the development of economic systems of different levels in the conditions of the powers transformation should contain the analysis of social, economic and ecological development of regions; spheres of possible dangers of the development of regional economic systems; the nature of the threats; the degree of the possibility of threats; time perspective of economic development threats; possible consequences of losses for economic entities; the impact of threats to the object of the economic entities' activity; possible asymmetry of economic development of regional economic entities. Possible threats as a consequence of the powers transformation have been identified. A PEST analysis of the impact of factors of different nature on economic security and the development of regional economic systems in the powers transformation is carried out. A recurrent ratio is proposed for the economic security system in the conditions of the powers transformation.

Intelligent Data Governance for the Federated Integration of Air Quality Databases in the Railway Industry (철도 산업의 공기 질 데이터베이스 연합형 통합을 위한 지능형 데이터 거버넌스)

  • Minjeong, Kim;Jong-Un, Won;Sangchan, Park;Gayoung, Park
    • Journal of Korean Society for Quality Management
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    • v.50 no.4
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    • pp.811-830
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    • 2022
  • Purpose: In this paper, we will discuss 1) prioritizing databases to be integrated; 2) which data elements should be emphasized in federated database integration; and 3) the degree of efficiency in the integration. This paper aims to lay the groundwork for building data governance by presenting guidelines for database integration using metrics to identify and evaluate the capabilities of the UK's air quality databases. Methods: This paper intends to perform relative efficiency analysis using Data Envelope Analysis among the multi-criteria decision-making methods. In federated database integration, it is important to identify databases with high integration efficiency when prioritizing databases to be integrated. Results: The outcome of this paper aims not to present performance indicators for the implementation and evaluation of data governance, but rather to discuss what criteria should be used when performing 'federated integration'. Using Data Envelope Analysis in the process of implementing intelligent data governance, authors will establish and present practical strategies to discover databases with high integration efficiency. Conclusion: Through this study, it was possible to establish internal guidelines from an integrated point of view of data governance. The flexiblity of the federated database integration under the practice of the data governance, makes it possible to integrate databases quickly, easily, and effectively. By utilizing the guidelines presented in this study, authors anticipate that the process of integrating multiple databases, including the air quality databases, will evolve into the intelligent data governance based on the federated database integration when establishing the data governance practice in the railway industry.

An External and Micromorphological Identification for Pharbitidis Semen and its Congeneric Species (외부 및 미세형태 비교를 통한 견우자(牽牛子) 기원종 및 동속이종(同屬異種) 감별)

  • Song, Jun-Ho;Yang, Sungyu;Choi, Goya;Moon, Byeong Cheol
    • The Korea Journal of Herbology
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    • v.33 no.4
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    • pp.43-51
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    • 2018
  • Objectives : Pharbitidis Semen, the seeds of Ipomoea nil (L.) Roth or I. purpurea (L.) Roth, is well-known traditional herbal medicine in Korea. But it is often marketed as a different seed or mixtures of its closely related species. Thus, the present study aims to provide external and micromorphological characters and identification key by using stereoscope (ST) and scanning electron microscope (SEM) for discriminating authentic of Pharbitidis Semen. Methods : A discrimination on external morphological characteristics of sepals, fruits, seeds, and hilum, testa cell micromorphology in the original plants and its congeneric species was carried out using digital calipers, ST, and SEM. Results : Number of valves (degree of apex of each valve), number of seeds per locule, hairy in capsules and size, luster, density of hairy, hilum shape in seeds and shape of cell, anticlinal, periclinal wall in testa may have high discriminative value. The seeds of Ipomoea nil as an original plant of Pharbitidis Semen were distinguished from other species by the relative larger in size, ovoid-trigonous in shape, mostly flabellate or triangular to trapezoid in outline (c.s.), dull, and puberulent in surface and thicken anticlinal wall. Conclusions : On the basis of the results, an identification key of Pharbitidis Semen and closely related species is provided. Our observations suggest that the combination of morphological characters and other studied results could be helpful in the successfully identified authentic herbal medicines. Moreover, micromorphological characters using SEM could be useful for discriminating authentic medicines.

Vegetation Changes in Forest Restoration Areas in National Parks (국립공원 내 전국 우수 산림생태 복원지역 식생 회복 평가)

  • Jung, Tae-Jun;Kim, Young-Sun;Kim, Young-Jin;Kim, Yeon-Gyeong;Cho, Eun-Suk;Cho, Dong-gil
    • Journal of Environmental Science International
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    • v.31 no.5
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    • pp.389-404
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    • 2022
  • The purpose of this study is to evaluate the vegetation recovery status of Mudeungsan National Park Jungmeorijae, Jeungsimsa district restoration site, and the Shimwon Valley ecological landscape restoration site in Jirisan National Park. Compared to the control plots, the Jungmeorijae restoration site was analyzed to have height growth of about 73.5%, the average species diversity index of about 75.2%. and the average similarity index was recovered to 7.75%. In the case of the restoration site in Jeungsimsa district, the height growth compared to the control plots was about 69.2%, the average species diversity index was about 55.0%. and the average similarity index was recovered to 25.65%. In the case of the Shimwon Valley ecological landscape restoration area, the height growth compared to the control plots was about 32.6%, the average species diversity index about 176.7%. and the average similarity index was recovered to 0.85%. The restoration site of the Jeungsimsa district was planted with relatively large trees during restoration work, and it took a relatively long time(20 years). Also, the site had less limiting factors due to the low elevation, allowing the degree of vegetation recovery to be higher than that of other sites.

Subgingival pathogens in chronic periodontitis patients affected by type 2 diabetes mellitus: a retrospective case-control study

  • Montevecchi, Marco;Valeriani, Leoluca;Gatto, Maria Rosaria;D'Alessandro, Giovanni;Piana, Gabriela
    • Journal of Periodontal and Implant Science
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    • v.51 no.6
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    • pp.409-421
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    • 2021
  • Purpose: The aim of this study was to compare the prevalence and bacterial load of 6 main periodontal pathogens between pairs of periodontal patients with and without type 2 diabetes mellitus. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans genotypes were also investigated. Methods: Twenty patients affected by chronic periodontitis and type 2 diabetes were retrospectively selected and matched to 20 patients without diabetes on the basis of the degree and severity of periodontal disease. Microbiological data of subgingival biofilms were analysed and compared for the examined pathogens: A. actinomycetemcomitans, P. gingivalis, Prevotella intermedia, Treponema denticola, Fusobacterium nucleatum, and Tannerella forsythia. Results: The pairs were balanced in terms of demographic and clinical parameters, except for bleeding on probing and suppuration. In the microbiological test sites (4 for each patient), the mean probing pocket depth was 6.34±1.63 mm in patients with diabetes and 6.41±1.78 mm in patients without diabetes. No significant difference between pairs in the prevalence of P. gingivalis or the distribution of its genotypes was recorded. Patients with diabetes had a significantly greater amount of total bacterial load, P. gingivalis, T. denticola, T. forsythia, and F. nucleatum (P<0.05). Moreover, patients with diabetes had a higher number of sites with a greater cell count than patients without diabetes. When compared to the total bacterial load, only T. forsythia maintained its relative load in patients with diabetes (P=0.001). Conclusions: This retrospective matched study supports the hypothesis that microbiological differences exist among periodontal patients with and without diabetes mellitus.