• Title/Summary/Keyword: Relative bias

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Outcomes of thin versus thick-wire snares for cold snare polypectomy: a systematic review and meta-analysis

  • Suprabhat Giri;Vaneet Jearth;Harish Darak;Sridhar Sundaram
    • Clinical Endoscopy
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    • v.55 no.6
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    • pp.742-750
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    • 2022
  • Background/Aims: Cold snare polypectomy (CSP) is commonly used for the resection of colorectal polyps ≤10 mm. Data regarding the influence of snare type on CSP effectiveness are conflicting. Hence, this meta-analysis aimed to compare the outcomes and safety of thin- and thick-wire snares for CSP. Methods: A comprehensive search of the literature published between 2000 and 2021 was performed of various databases for comparative studies evaluating the outcomes of thin- versus thick-wire snares for CSP. Results: Five studies with data on 1,425 polyps were included in the analysis. The thick-wire snare was comparable to the thin-wire snare with respect to complete histological resection (risk ratio [RR], 1.03; 95% confidence interval [CI], 0.97-1.09), overall bleeding (RR, 0.98; 95% CI, 0.40-2.40), polyp retrieval (RR, 1.01; 95% CI, 0.97-1.04), and involvement of submucosa in the resection specimen (RR, 1.28; 95% CI, 0.72-2.28). There was no publication bias and a small study effect, and the relative effects remained the same in the sensitivity analysis. Conclusions: CSP using a thin-wire snare has no additional benefit over thick-wire snares in small colorectal polyps. Factors other than snare design may play a role in improving CSP outcomes.

Regional Frequency Analysis for Rainfall using L-Moment (L-모멘트법에 의한 강우의 지역빈도분석)

  • Koh, Deuk-Koo;Choo, Tai-Ho;Maeng, Seung-Jin;Trivedi, Chanda
    • The Journal of the Korea Contents Association
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    • v.8 no.3
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    • pp.252-263
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    • 2008
  • This study was conducted to derive the optimal regionalization of the precipitation data which can be classified on the basis of climatologically and geographically homogeneous regions all over the regions except Cheju and Ulreung islands in Korea. A total of 65 rain gauges were used to regional analysis of precipitation. Annual maximum series for the consecutive durations of 1, 3, 6, 12, 24, 36, 48 and 72hr were used for various statistical analyses. K-means clustering mettled is used to identify homogeneous regions all over the regions. Five homogeneous regions for the precipitation were classified by the K-means clustering. Using the L-moment ratios and Kolmogorov-Smirnov test, the underlying regional probability distribution was identified to be the generalized extreme value (GEV) distribution among applied distributions. The regional and at-site parameters of the generalized extreme value distribution were estimated by the linear combination of the probability weighted moments, L-moment. The regional and at-site analysis for the design rainfall were tested by Monte Carlo simulation. Relative root-mean-square error (RRMSE), relative bias (RBIAS) and relative reduction (RR) in RRMSE were computed and compared with those resulting from at-site Monte Carlo simulation. All show that the regional analysis procedure can substantially reduce the RRMSE, RBIAS and RR in RRMSE in the prediction of design rainfall. Consequently, optimal design rainfalls following the regions and consecutive durations were derived by the regional frequency analysis.

A Meta-Analysis of Air Pollution in Relation to Daily Mortality in Seven Major Cities of Korea, 1998-2001 (메타분석을 적용한 전국 7개 대도시의 대기오염과 일일사망발생의 상관성 연구(1998년$\sim$2001년))

  • Cho, Yong-Sung;Lee, Jong-Tae;Son, Ji-Young;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
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    • v.32 no.4 s.91
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    • pp.304-315
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    • 2006
  • This study is performed to reexamine the association between ambient air pollution and daily mortality in seven major cities of Korea using a method of meta-analysis with the data filed for the period 1998-2001. These cities account for half of the Korean population (about 23 million). The observed concentrations of carbon monoxide (CO, mean=1.08 ppm), ozone ($O_3$, mean=33.97 ppb), particulate matter less than 10 ${\mu}m$ ($PM_{10},\;mean=57.11\;{\mu}g/m^3$), nitrogen dioxide ($NO_2$, mean=25.09 ppb), and sulfur dioxide ($SO_2$, mean=9.14 ppb) during the study period were at levels below Korea's current ambient air quality standards. Generalized additive models were applied to allow for the highly flexible fitting of seasonal and long-term time trends in air pollution as well as nonlinear associations with weather variables, such as air temperature and relative humidity. Also, we calculated a weighted mean as a meta-analysis summary of the estimates and its standard error. In city-specific analyses, an increase of $41.17{\mu}g/m^3(IQR)\;of\;PM_{10}$ corresponded to $1{\sim}12%$ more deaths, given constant weather conditions. Like most of air pollution epidemiologic studies, this meta-analysis cannot avoid fleeing from measurement misclassification since no personal measurement was taken. However, we can expect that a measurement bias be reduced in district-specific estimate since a monitoring station is better representative of air quality of the matched district. Significant heterogeneity was found for the effect of all pollutants. The estimated relative risks from meta-like analysis increased compared to those relative risks from pooled analysis. The similar results to those from the previous studies indicated existence of health effect of air pollution at current levels in many industrialized countries, including Korea.

Evaluation of the proficiency testing results using river water-based reference materials for heavy metal analysis (중금속분석용 하천수 매질표준물질을 이용한 숙련도 결과 평가)

  • Song, Ko-Bong;Kim, Young-Hee;Shin, Sun-Kyoung;Lee, Su-Yeong;Kim, Hyun-Jung;Kang, Hak-Gu;Kim, Il-Gyu;An, Hee-Ju
    • Analytical Science and Technology
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    • v.23 no.3
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    • pp.284-294
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    • 2010
  • In this study, river water-based reference materials (RMs), NIER-I08RW and NIER-I09, for trace metal analysis were prepared and certified for Pb, Cd, Cr and Cu with evaluation of uncertainties. The RMs were confirmed to be homogeneous enough to be used as proficiency testing materials since within-bottle homogenieties of the RMs were lower than 0.3 times of targeted standard deviation of proficiency testing. The RMs were distributed to environmental testing laboratories for the proficiency testing and the variation of Z scores of the proficiency testing results were compared for different assigned values. The relative bias, $B_{relative}$, deviations between reference values and consensus values, were lower than ${\pm}$1 except for cadmium of NIERI08RW. The results showed both values were in a good agreement and only 2.9% of Z scores changed by using a different assigned values such as consensus and reference values.

Impacts of Relative Advantage of Fast Food Restaurant's O2O Service and Consumer Involvement on Consumer Engagement, and Store Loyalty: Focused on MZ Generationsin Untact Consumption Era

  • LEE, Young-Eun;LEE, Yong-Ki
    • The Korean Journal of Franchise Management
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    • v.11 no.2
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    • pp.41-51
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    • 2020
  • Purpose: Fast food franchise companies are trying a variety of innovative services to increase their competitiveness in response to changes in population composition in the fast food market and rapid changes in consumption trends due to technological development. From this point of view, franchise companies that have focused on offline store operations are providing O2O (offline to online) service as a core service for customer convenience. This new attempt is a strategy to increase loyalty by applying an interaction method based on understanding the characteristics of new generation consumers. However, existing studies are focused on the relationship between O2O service and acceptance, so very little is known about how O2O service affects customer loyalty. Therefore, this study examines the impacts of customer involvement and relative advantages of fast food O2O service on customer brand engagement (cognitive and affective engagement) and store loyalty for MZ(Millennials - Z) generations. Research design, data, and methodology: In order to achieve the purposes of this research, several hypotheses were developed. The data were collected from 247 questionnaires in their 16-30s and were analyzed using SPSS 22.0 and SmartPLS 3.0 program. Measurement model analysis was carried out to assess convergent and discriminant validity. Also, common method bias was tested using the values of VIF (variance inflation factor). The hypotheses was tested using structural equation modeling. Result: First, involvement has a positive effect on cognitive and affective engagement. Second, relative advantages have has a positive effect on cognitive and affective engagement. Third, cognitive influences affective engagement. Finally, both cognitive and affective engagement affect store loyalty, but affective engagement has a stronger effect on store loyalty than cognitive engagement. Conclusions: In the process of consumer-brand interaction, it was confirmed that store loyalty was influenced by cognitive and affective engagement sequentially. However, the results show that affective engagement has a relatively stronger on store loyalty than cognitive engagement. Therefore, it is necessary to establish an O2O service strategy to maintain long-term loyal customers by inducing cognitive participation with high-involved consumer, as well as affective interaction, in order to obtain new customers and increase customer loyalty.

The 33-mode Dielectric and Piezoelectric Properties of PIN-PMN-PT Single Crystal under Stress and Electric Field (압축하중 및 전계 인가에 따른 PIN-PMN-PT 단결정의 33-모드 유전 및 압전특성)

  • Lim, Jae Gwang;Park, Jae Hwan;Lee, Jeongho;Lee, Sang Goo
    • Journal of the Microelectronics and Packaging Society
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    • v.27 no.4
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    • pp.91-96
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    • 2020
  • The 33-mode dielectric and piezoelectric properties of Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 piezoelectric single crystals were measured under large electric field and compressive stress. The phase transition from the low temperature rhombohedral to the high temperature tetragonal structure was observed in the range of 110~140℃, and the Curie temperature changing to the cubic structure was about 165℃. The polarization change according to the compressive stress and electric field was measured. Relative dielectric constant was calculated from the slope of the polarization curve applied to the electric field, and the calculated relative dielectric constant increased as the applied stress increased, and the relative dielectric constant decreased as the applied electric field increased. The strain according to the compressive stress and electric field change was measured, the piezoelectric constant was calculated from the slope of the curve, and the phase transition according to the application of pressure was confirmed. In the case of practical application as an underwater or medical ultrasonic actuator, it is necessary to properly design the magnitude of the compressive stress applied to the device and the DC bias in order to maintain linear driving.

The GOCI-II Early Mission Ocean Color Products in Comparison with the GOCI Toward the Continuity of Chollian Multi-satellite Ocean Color Data (천리안해양위성 연속자료 구축을 위한 GOCI-II 임무 초기 주요 해색산출물의 GOCI 자료와 비교 분석)

  • Park, Myung-Sook;Jung, Hahn Chul;Lee, Seonju;Ahn, Jae-Hyun;Bae, Sujung;Choi, Jong-Kuk
    • Korean Journal of Remote Sensing
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    • v.37 no.5_2
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    • pp.1281-1293
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    • 2021
  • The recent launch of the GOCI-II enables South Korea to have the world's first capability in deriving the ocean color data at geostationary satellite orbit for about 20 years. It is necessary to develop a consistent long-term ocean color time-series spanning GOCI to GOCI-II mission and improve the accuracy through validation using in situ data. To assess the GOCI-II's early mission performance, the objective of this study is to compare the GOCI-II Chlorophyll-a concentration (Chl-a), Colored Dissolved Organic Matter (CDOM), and remote sensing reflectances (Rrs) through comparison with the GOCI data. Overall, the distribution of GOCI-II Chl-a corresponds with that of the GOCI over the Yellow Sea, Korea Strait, and the Ulleung Basin. In particular, a smaller RMSE value (0.07) between GOCI and GOCI-II over the summer Ulleung Basin confirms the GOCI-II data's reliability. However, despite the excellent correlation, the GOCI-II tends to overestimate Chl-a than the GOCI over the Yellow Sea and Korea Strait. The similar over-estimation bias of the GOCI-II is also notable in CDOM. Whereas no significant bias or error is found for Rrs at 490 nm and 550 nm (RMSE~0), the underestimation of Rrs at 443 nm contributes to the overestimation of GOCI-II Chl-a and CDOM over the Yellow Sea and the Korea Strait. Also, we show over-estimation of GOCI-II Rrs at 660 nm relative to GOCI to cause a possible bias in Total suspended sediment. In conclusion, this study confirms the initial reliability of the GOCI-II ocean color products, and upcoming update of GOCI-II radiometric calibration will lessen the inconsistency between GOCI and GOCI-II ocean color products.

Prognostic Role of Hypoxic Inducible Factor Expression in Non-small Cell Lung Cancer: A Meta-analysis

  • Li, Cong;Lu, Hua-Jun;Na, Fei-Fei;Deng, Lei;Xue, Jian-Xin;Wang, Jing-Wen;Wang, Yu-Qing;Li, Qiao-Ling;Lu, You
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3607-3612
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    • 2013
  • Introduction: Reported prognostic roles of hypoxic inducible factor (HIF) expression in non-small cell lung cancer (NSCLC) have varied. This meta-analysis aimed to examine the relationship between HIF expression and clinical outcome in NSCLC patients. Methods: PubMed were used to identify relevant literature with the last report up to December $20^{th}$, 2012. After careful review, survival data were collected from eligible studies. We completed the meta-analysis using Stata statistical software (Version 11) and combined hazard ratio (HR) for overall survival (OS). Subgroup specificity, heterogeneity and publication bias were also assessed. All of the results were verified by two persons to ensure accuracy. Results: Eight studies were finally stepped into this meta-analysis in which seven had available data for HIF-$1{\alpha}$ and three for HIF-$2{\alpha}$. Combined HRs suggested that higher expression of $HIF1{\alpha}$ had a negative impact on NSCLC patient survival (HR=1.50; 95%CI=1.07-2.10; p=0.019). The expression of HIF-$2{\alpha}$ was also relative to a poorer survival (HR=2.02; 95%CI=1.47-2.77; p=0.000). No bias existed in either of the two groups. Conclusion: This study suggests that elevations of HIF-$1{\alpha}$ and HIF-$2{\alpha}$ expression are both associated with poor outcome for patients with NSCLC. The data support further and high quality investigation of HIF expression for predicting poor outcome in patients with NSCLC.

Asymmetric Saturated 3-Stage Doherty Power Amplifier Using Envelope Tracking Technique for Improved Efficiency (효율 향상을 위해 포락선 추적 기술을 이용한 비대칭 포화 3-Stage 도허터 전력 증폭기)

  • Kim, Il-Du;Jee, Seung-Hoon;Moon, Jung-Hwan;Son, Jung-Hwan;Kim, Jung-Joon;Kim, Bum-Man
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.8
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    • pp.813-822
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    • 2009
  • We have investigated operation of a 1:2:2 asymmetric 3-stage Doherty PA(Power Amplifier) and implemented using the Freescale's 4 W, 10 W PEP LDMOSFETS at 1 GHz. By employing the three peak efficiency characteristics, compared to the two peak N-way Doherty PA, the asymmetric 3-stage Doherty can overcome the serious efficiency degradation along the backed-off output power region and maximize the average efficiency for the modulation signal. To maximize the efficiency characteristic, the inverse class F PA has been designed as carrier and peaking amplifiers. Furthermore, to extract the proper load modulation operation, the adaptive gate bias control signal has been applied to the two peaking PAs based on the envelope tracking technique. For the 802.16e Mobile WiMAX(World Interoperability for Microwave Access) signal with 8.5 dB PAPR(Peak to Average Power Ratio), the proposed Doherty PA has shown 55.46 % of high efficiency at an average output power of 36.85 dBm while maintaining the -37.23 dB of excellent RCE(Relative Constellation Error) characteristic. This is the first time demonstration of applying the saturated PA and adaptive gate bias control technique to the asymmetric 3-stage Doherty PA for the highly efficient transmitter of the base-station application.

Hydrogeneted Amorphous Carbon Nitride Films on Si(100) Deposited by DC Saddle Field Plasma Enhanced Chemical Vapor Deposition ($N_2/CH_4$가스비에 따른 Hydrogenated Amorphous Carbon Nitride 박막의 특성)

  • 장홍규;김근식;황보상우;이연승;황정남;유영조;김효근
    • Journal of the Korean Vacuum Society
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    • v.7 no.3
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    • pp.242-247
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    • 1998
  • Hydrogenated amorphous carbon nitride[a-C:H(N)] films were deposited on p-type Si(100) at room temperature with bias voltage of 200 V by DC saddle-field plasma-enhanced chemical vapor deposition. Effects of the ratio of $N_2$ to $CH_4$($N_2/CH_4$), in the range of 0 and 4 on such properties as optical properties, microstucture, relative fraction of nitrogen and carbon, etc. of the films have been investigated. The thickness of the a-C:H(N) film was abruptly decreased with the addition of nitrogen, but at $N_2/CH_4$>0.5, the thickness of the film gradually decreased with the increase of the $N_2/CH_4$. The ratio of N to C(N/C) of the films was saturated at 0.25 with the increase of $N_2CH_4$. N-H, C≡N bonds of the films increased but C-H bond decreased with the increase of $N_2CH_4$.Optical band gap energy of the film decreased from 2.53 eV at the ratio of $N_2CH_4$=4.

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