• 제목/요약/키워드: Related Content

검색결과 5,662건 처리시간 0.035초

지방세포 분화중인 3T3-L1 세포에서 영지추출물에 의한 지방관련 유전자와 전사인자의 발현 조절 (Adipocyte-Related Genes and Transcription Factors were affected by Ganoderma lucidum during 3T3-L1 Differentiation)

  • 이채우;윤현민;강경화
    • 대한약침학회지
    • /
    • 제12권2호
    • /
    • pp.13-20
    • /
    • 2009
  • In this study, the effects of Ganoderma lucidum (GL) on fat metabolism were performed in 3T3-L1 adipocytes. The effects of GL on 3T3-L1 preadipocytes differentiation were also examined. Our results showed that GL decreased the TG content by ORO staining. To elucidate the mechanism of the effects of GL on lowering TG content in 3T3-L1 adipocytes, we examined whether GL modulate the expressions of transcription factors and adipokines related to control of energy expenditure process because adipokines regulate adipocyte mass and increased expenditure may consume much TG in adipocytes. As a result, the expression of C/$EBP{\beta}$, C/$EBP{\delta}$, C/$EBP{\alpha}$, and $PPAR{\gamma}$, genes, which induce the adipose differentiation and adipose-specific FAS, aP2, and adipsin genes, which compose fat formation were decreased. In addition, GL increased the expression of leptin, UCP2, adiponectin in 3T3-L1 adipocytes, resulting in energy homeostasis. In conclusion, GL could regulate transcript factor related to induction of adipose differentiation and control TG content by up-regulation of adipokines related to fat burn.

구조적 토픽모델링을 활용한 무료형 대규모 다중이용자 온라인 롤플레잉 게임의 소액결제에 대한 이용자 리뷰 분석 (User Review Analysis of Microtransactions in Freemium Massively Multiplayer Online Role-Playing Games Using Structural Topic Modeling)

  • 이철;정재은
    • Human Ecology Research
    • /
    • 제61권3호
    • /
    • pp.475-492
    • /
    • 2023
  • This study investigated player responses to microtransactions in freemium Massively multiplayer online roleplaying games (MMORPG), specifically focusing on the game LostArk using English language review data. To this end, structural topic modeling was employed and the following six microtransaction-relevant topics were identified: microtransactions, developer issues, real money trade (RMT), random number generator (RNG) upgrade system, game content, and collectibles & adventure. The first four topics were classified as being "not recommended". However, the proportions of microtransaction-related topics were relatively lower than the other topics. Additionally, this study did not extract keywords related to unfairness and unethical issues in previous microtransaction research. The last two topics, game content, and collectibles & adventure were "recommended" topics, indicating positive functions of microtransactions such as enhancing the game experience by purchasing virtual items. Moreover, it was found that players who do not engage in microtransactions can still be satisfied through continuous game content updates. Additionally, an examination of the interaction effect between time and recommendation status revealed that while the frequency with which the six microtransaction-related topics were mentioned increased over time in the reviews, the ratio of recommendations to non-recommendations varied differently. This study contributes to game-related research by revealing players' authentic opinions on microtransactions in freemium MMORPGs, thereby providing practical implications for game companies.

Quality evaluation of pregnancy-related mobile applications in South Korea: a descriptive study

  • Hyunjin Cho;Feiyan Yi;Sukhee Ahn
    • 여성건강간호학회지
    • /
    • 제29권3호
    • /
    • pp.190-199
    • /
    • 2023
  • Purpose: This study aimed to describe the characteristics of mobile applications (apps) related to pregnancy in South Korea and evaluate their quality. Methods: We conducted a systematic search for pregnancy-related apps available in Korea in two app stores as of April 29, 2022. The quality of apps was assessed using the Korean translation of the Mobile Application Rating Scale for objective quality with four subdomains (engagement, function, aesthetics, and information) and four items for subjective quality. Results: In total, 163 apps were selected and reviewed. Both the objective and subjective quality of the apps were found to be desirable, with scores exceeding 3 out of 5 (range, 34-82). All subdomain scores in the objective quality assessment were also desirable. Among the four objective quality subdomains, aesthetics received the highest scores, followed by information, function, and engagement. In terms of subjective quality, the scores for a comprehensive overall evaluation, continuous use, and recommendation exceeded 3 out of 5, with the exception of payment. Only a small number of apps (n=4, 2.9%) were backed by a reliable authority, such as an expert review. Significant differences were observed in the objective quality of apps across different content categories (F=3.86, p=.003). Conclusion: Most pregnancy-related apps had desirable levels of objective and subjective quality. However, app content experts seldom provide reviews. It is crucial for nurses to recommend apps to expectant mothers that offer dependable content, regularly updated with the latest information.

흙-수분 특성곡선 방정식을 이용한 체적함수비의 예측 (Prediction of the Volumetric Water Content Using the Soil-Water Characteristic Curve on an Unsaturated Soil)

  • 송창섭
    • 한국환경복원기술학회지
    • /
    • 제7권6호
    • /
    • pp.39-48
    • /
    • 2004
  • The purpose of this paper was to confirm the application of the equation of the soil-water characteristic curve on an unsaturated soil. To this ends, a series of suction test was conducted on the selected 4 kinds of soil which is located in Korea, using the modified pressure extractor apparatus. And it was carried out to analyze the experimental parameters which can describe the soil-water characteristics, were determined by using the data obtained from the experiment. From the results, it was found that the matric suction was varied according to the grain size distribution, amount of fine grain particle and void ratio. Also it was found that the residual volumetric water content was decreased with the void ratio, but the index related air entry value, the soil parameter related water content and the parameter with residual water content were increased with the void ratio. And the application of equation of the soil-water characteristic curve was confirmed for the various conditions and the various state by the comparison between the volumetric water content measured by the experiment and the predicted values.

동죽(Mactra veneriformis)가공에 따른 정미성분의 변화 (Changes in Taste Compounds of Processed Surf Clam(Mactra veneriformis))

  • 류화정;고영수
    • 한국식품과학회지
    • /
    • 제17권3호
    • /
    • pp.223-226
    • /
    • 1985
  • 동죽은 자숙하여 천일건조시료, 열풍건조시료로 만들어서 일반성분과 정미성분으로 알려져 있는 핵산관련물질, 유리아미노산, glycogen의 함량의 변화를 비교하였다. 일반성분은 가공전후에서 큰 차이가 없었으나 회분함량은 가공후 21.5%가 증가하였다. 핵산관련 물질은 생시료에는 ATP, ADP, IMP 및 Hypoxanthine이 많았으나 건조시료에서는 ATP는 상당량(78%)줄었고 다른 핵산관련물질도 모두 줄어들었다. 유리아미노산은 glycine, alanine 및 arginine이 전체 유리아미노산의 85%를 차지하고 있었으며 건조후 유리아미노산은 전체적으로 생시료의 60%정도를 함유하고 있었다. 동죽자건품의 중요한 정미성분은 glycine, alanine, arginine과 같은 유리아미노산 및 ATP 분해생성물이라고 추정할 수 있다.

  • PDF

Relationship between Water Content and Osmotic Potential of Lentinula edodes

  • Koo, Chang-Duck;Cho, Sun-Young
    • Mycobiology
    • /
    • 제36권1호
    • /
    • pp.24-27
    • /
    • 2008
  • This study was conducted to understand how osmotic potentials in Lentinula edodes tissues are related to water contents and how they change while a mushroom matures. Water content and osmotic potential of L. edodes mushroom tissues from log cultivation and sawdust cultivation were measured and the relationships were analyzed. Osmotic potentials in the tissues were exponentially proportional to their moisture contents and there were strain differences in the potentials. Strain 290 has lower osmotic potential than strain 302, in the tissues at the same water content. As the mushrooms mature, tissue water content maintained ca 94% in head tissues and ca 90% in gills, but significantly decreased from ca 90% to 82% in the stipe tissues. Osmotic potential changes were similar to the tissue water content changes as the mushrooms mature. While osmotic potentials maintained -0.25 to -0.45 MPa in head and gill tissues, the potentials greatly decreased from -0.65 to -1.33 MPa in stipe tissues. Our results show that osmotic potentials in L. edodes tissues are exponentially proportional to tissue water contents, that strains differ in osmotic potential related to water, and that stipe tissues can still have nutritional value when they mature.

The Relationship between Chemical Compositions, Meat Quality, and Palatability of the 10 Primal Cuts from Hanwoo Steer

  • Jung, Eun-Young;Hwang, Young-Hwa;Joo, Seon-Tea
    • 한국축산식품학회지
    • /
    • 제36권2호
    • /
    • pp.145-151
    • /
    • 2016
  • The relationship between chemical compositions, meat quality traits, and palatability attributes in 10 primal cuts from Hanwoo steer carcasses were assessed. Sensory palatability attributes of Hanwoo beef were more closely related with fat content than to moisture or protein content. Among the chemical compositions, only fat had a significant correlation with juiciness (0.67, p<0.001), tenderness (0.32, p<0.05), and overall palatability (0.56, p<0.001). Oleic acid (%) was not significantly related with overall palatability (p>0.05). Overall palatability was negatively correlated with drip loss (−0.32, p<0.05), cooking loss (−0.36, p<0.05), and shear force (−0.54, p<0.01). The correlation between fat content and overall palatability was increased when higher fat cuts (Ansim, Dungsim, Chaekeut, Yangjee, and Kalbi) were analyzed, compared to lower fat cuts (Moksim, Abdari, Udun, Suldo, and Satae). Also, the correlation between shear force and overall palatability was decreased in lower fat cuts compared to higher fat cuts. Our results suggest that the palatability of Hanwoo beef can be improved by increasing fat content in muscles, as increased fat content leads to an increase in sensory tenderness, flavor, and juiciness.

IT서비스 기술인력의 경력정체가 경력만족 및 경력변경의도에 미치는 영향 (The effect of career plateau on IT service engineers' career satisfaction and career withdrawal intention)

  • 박경환
    • 디지털융복합연구
    • /
    • 제9권4호
    • /
    • pp.115-130
    • /
    • 2011
  • 본 연구는 IT서비스 기술인력의 경력정체(구조적 정체, 내용적 정체)가 경력만족 및 경력변경의 도에 미치는 영향을 분석하였다. 161명의 IT서비스 기술인력으로 부터 데이터를 수집하였다. 구조적 정체와 내용적 정체는 각각 경력만족에 부의 유의한 상관을 갖고 있었다. 그리고 내용적 정체는 경력변경의도와 정의 유의한 상관을 갖고 있었으며, 구조적 정체는 이와 유의한 상관을 갖고 있지 않았다. 위계적 다중회귀분석에 의한 상대적 영향력 분석 결과 구조적 정체 보다 내용적 정체가 경력만족 및 경력변경의도에 더 큰 유의한 영향을 미치고 있었다. 마지막으로 본 연구는 IT서비스 기술인력의 경력정체를 극복하기 위한 방안을 제시하고 있다.

Development of Contents for Effective Computer Programming Education in Curriculum of Elementary Schools

  • Kim, Jong-soo;Kwon, Soon-kak
    • Journal of Multimedia Information System
    • /
    • 제6권3호
    • /
    • pp.147-154
    • /
    • 2019
  • In a variety of fields, highly developed technology is being combined to create a lot of value. In order to keep up with this global trend, the Ministry of Education, which is in charge of national education, continuously develops and applies content for creative education to textbooks. The continuous development of content for creative education is not only related to national interests, but also to the continued development of mankind. Today, the succession and development of human knowledge is in charge of the education system. Research into an effective educational system is necessary for effective succession of rapidly developing science and technology and building up technical personnel with such skills. In particular, the computer science field is faster in development than other scientific fields and has accumulated many technologies, indicating that it takes a lot of time and good teaching to foster talent that can effectively utilize the technology. In this paper, elementary school subjects were analyzed to achieve the purpose of cultivating talent in the field of computer science. In addition, we have investigated techniques related to computer programming learning not covered in elementary school subjects. So we developed content that students need to practice. Next, we taught the content to randomly selected elementary school students and assessed their educational effectiveness. As a result of training using the content we developed, 55.37% increased academic performance.

Predicting Learning Achievements with Indicators of Perceived Affordances Based on Different Levels of Content Complexity in Video-based Learning

  • Dasom KIM;Gyeoun JEONG
    • Educational Technology International
    • /
    • 제25권1호
    • /
    • pp.27-65
    • /
    • 2024
  • The purpose of this study was to identify differences in learning patterns according to content complexity in video-based learning environments and to derive variables that have an important effect on learning achievement within particular learning contexts. To achieve our aims, we observed and collected data on learners' cognitive processes through perceived affordances, using behavioral logs and eye movements as specific indicators. These two types of reaction data were collected from 67 male and female university students who watched two learning videos classified according to their task complexity through the video learning player. The results showed that when the content complexity level was low, learners tended to navigate using other learners' digital logs, but when it was high, students tended to control the learning process and directly generate their own logs. In addition, using derived prediction models according to the degree of content complexity level, we identified the important variables influencing learning achievement in the low content complexity group as those related to video playback and annotation. In comparison, in the high content complexity group, the important variables were related to active navigation of the learning video. This study tried not only to apply the novel variables in the field of educational technology, but also attempt to provide qualitative observations on the learning process based on a quantitative approach.