• 제목/요약/키워드: Regulatory information

검색결과 666건 처리시간 0.024초

Quantitative and Qualitative Extrapolation of Carcinogenesis Between Species

  • Gold Lois Swirsky;Manley Neela B.;Ames Bruce N.
    • 대한예방의학회:학술대회논문집
    • /
    • 대한예방의학회 1994년도 교수 연수회(환경)
    • /
    • pp.431-438
    • /
    • 1994
  • As currently conducted, standard rodent bioassays do not provide sufficient information to assess carcinogenic risk to humans at doses thousands of times below the maximum tolerated dose. Recent analyses indicate that measures of carcinogenic potency from these tests are restricted to a narrow range about the maximum tolerated dose and that information on shape of the dose-response is limited in experiments with only two doses and a control. Extrapolation from high to low doses should be based on an understanding of the mechanisms of carcinogenesis. We have postulated that administration of the maximum tolerated dose can increase mitogenesis which, in turn. increases rates of mutagenesis and, thus, carcinogenesis. The animal data are consistent with this mechanism, because about half of all chemicals tested are indeed rodent carcinogens, and about 40% of the positives are not detectably mutagenic. Thus, at low doses where cell killing does not occur, the hazards to humans of rodent carcinogens may be much lower than commonly assumed. In contrast, for high-dose exposures in the workplace, assessment of hazard requires comparatively little extrapolation. Nevertheless. permitted workplace exposures are sometimes close to the tumorigenic dose-rate in animal tests. Regulatory policy to prevent human cancer has primarily addressed synthetic chemicals, yet similar proportions of natural chemicals and synthetic chemicals test positive in rodent studies as expected from an understanding of toxicological defenses, and the vast proportion of human exposures are to natural chemicals. Thus, human exposures to rodent carcinogens are common. The natural chemicals are the control to evaluate regulatory strategies, and the possible hazards from synthetic chemicals should be compared to the possible hazards from natural chemicals. Qualitative extrapolation of the carcinogenic response between species has been investigated by comparing two closely related species: rats and mice. Overall predictive values provide moderate confidence in interspecies extrapolation; however, knowing that a chemical is positive at any site in one species gives only about a 50% chance that it will be positive at the same site in the other species.

  • PDF

모듈형 제품의 옵션 수가 소비자의 과잉혼란 지각에 미치는 영향 -조절초점, 제품친숙도, 자기효능감의 조절효과를 중심으로- (Study on Perceived Overload Confusion due to Modular Product's Option Size)

  • 김건
    • 한국콘텐츠학회논문지
    • /
    • 제17권4호
    • /
    • pp.275-284
    • /
    • 2017
  • 다양한 선택사항이 있는 모듈형 제품은 제품 구조나 배열 변경의 용이성을 장점으로 소비자들의 제품선택 폭을 확대해주고 맞춤형 제품의 구매기회를 제공해 준다. 또한 생산자로서의 소비자 역할을 수행케 함으로써 구매 후 부조화 감소와 제품 사용과정에서의 이용만족도도 높여 준다. 하지만 과도한 모듈화 또는 선택사항의 증가는 소비자들의 구매의사결정과정에서 정보량 과다에 따른 소비자의 과잉혼란을 유발하여 구매결정의 연기 및 포기하는 부정적 결과를 유발할 수도 있다. 이에 본 연구에서는 선택 사항 즉 옵션 수에 따라 달라질 수 있는 과잉혼란의 지각 정도가 소비자들의 심리적 성향인 조절초점, 제품친숙도, 자기효능감 등에 의해 어떤 영향을 받는지 살펴보고자 한다. 이를 위해 모듈형 제품의 옵션 수에 따른 과잉혼란 지각정도가 이들 세 가지 변수의 영향에 따라 달라질 수 있다는 3가지 조절효과 가설을 선행연구에 근거하여 도출하였다. 실험 결과 조절초점의 조절효과 검증에서는 향상초점 소비자에 비해 예방초점 소비자가 옵션 수 확장에 따른 과잉혼란을 더 크게 지각하는 것으로 나타났다. 또한 제품친숙도와 자기효능감의 조절효과 검증에서는 이들 두 변수 모두 그 정도가 낮은 그룹이 높은 그룹에 비해 옵션 수 확장에 따라 과잉혼란을 더 크게 지각하는 것으로 나타났다.

Computation of geographic variables for air pollution prediction models in South Korea

  • Eum, Youngseob;Song, Insang;Kim, Hwan-Cheol;Leem, Jong-Han;Kim, Sun-Young
    • Environmental Analysis Health and Toxicology
    • /
    • 제30권
    • /
    • pp.10.1-10.14
    • /
    • 2015
  • Recent cohort studies have relied on exposure prediction models to estimate individual-level air pollution concentrations because individual air pollution measurements are not available for cohort locations. For such prediction models, geographic variables related to pollution sources are important inputs. We demonstrated the computation process of geographic variables mostly recorded in 2010 at regulatory air pollution monitoring sites in South Korea. On the basis of previous studies, we finalized a list of 313 geographic variables related to air pollution sources in eight categories including traffic, demographic characteristics, land use, transportation facilities, physical geography, emissions, vegetation, and altitude. We then obtained data from different sources such as the Statistics Geographic Information Service and Korean Transport Database. After integrating all available data to a single database by matching coordinate systems and converting non-spatial data to spatial data, we computed geographic variables at 294 regulatory monitoring sites in South Korea. The data integration and variable computation were performed by using ArcGIS version 10.2 (ESRI Inc., Redlands, CA, USA). For traffic, we computed the distances to the nearest roads and the sums of road lengths within different sizes of circular buffers. In addition, we calculated the numbers of residents, households, housing buildings, companies, and employees within the buffers. The percentages of areas for different types of land use compared to total areas were calculated within the buffers. For transportation facilities and physical geography, we computed the distances to the closest public transportation depots and the boundary lines. The vegetation index and altitude were estimated at a given location by using satellite data. The summary statistics of geographic variables in Seoul across monitoring sites showed different patterns between urban background and urban roadside sites. This study provided practical knowledge on the computation process of geographic variables in South Korea, which will improve air pollution prediction models and contribute to subsequent health analyses.

Through the Looking Glass: The Role of Portals in South Korea's Online News Media Ecology

  • Dwyer, Tim;Hutchinson, Jonathon
    • Journal of Contemporary Eastern Asia
    • /
    • 제18권2호
    • /
    • pp.16-32
    • /
    • 2019
  • Media manipulation of breaking news through article selection, ranking and tweaking of social media data and comment streams is a growing concern for society. We argue that the combination of human and machine curation on media portals marks a new period for news media and journalism. Although intermediary platforms routinely claim that they are merely the neutral technological platform which facilitates news and information flows, rejecting any criticisms that they are operating as de facto media organisations; instead, we argue for an alternative, more active interpretation of their roles. In this article we provide a contemporary account of the South Korean ('Korean') online news media ecology as an exemplar of how contemporary media technologies, and in particular portals and algorithmic recommender systems, perform a powerful role in shaping the kind of news and information that citizens access. By highlighting the key stakeholders and their positions within the production, publication and distribution of news media, we argue that the overall impact of the major portal platforms of Naver and Kakao is far more consequential than simply providing an entertaining media diet for consumers. These portals are central in designing how and which news is sourced, produced and then accessed by Korean citizens. From a regulatory perspective the provision of news on the portals can be a somewhat ambiguous and moving target, subject to soft and harder regulatory measures. While we investigate a specific case study of the South Korean experience, we also trace out connections with the larger global media ecology. We have relied on policy documents, stakeholder interviews and portal user 'walk throughs' to understand the changing role of news and its surfacing on a distinctive breed of media platforms.

자원 순환형 산업개발의 유형 연구 (A Study on the Current Practice in Eco-Industrial Development)

  • 문석웅
    • 자원ㆍ환경경제연구
    • /
    • 제12권2호
    • /
    • pp.347-382
    • /
    • 2003
  • 본 연구에서는 한국에서 생태적 산업개발을 추진할 경우에 선택할 수 있는 유형을 제시하고 있다. 즉, (1) 다양한 업종으로 구성된 생태산업단지 또는 생태산업 네트워크, (2) 클러스터와 제로 에미션 개념의 결합에 의한 부산물 교환 시스템, (3) 동종 산업으로 구성된 산업 단지에서의 제로 에미션 추구, (4) 포괄적인 지역개발 프로젝트로서의 EID 등이다. 국내에서 자원순환형 경제개발 정착을 위한 우선적 과제는 산업체들로 하여금 현재의 관행을 벗어나서 다른 기업과의 공생적 관계를 적극 모색하여 부산물교환을 촉진하는 제도적 여건을 조성하는 것, 산업체들이 부산물 활용 네트워크를 조직하는데 필요한 자금지원과 인센티브 도입, 부산물 교환을 위한 시장의 창출에 기여하는 정보네트워크의 구성, 산업체의 환경관련 교육 강화 등이다.

  • PDF

VR 테마파크 규제개선방안 (VR Theme Park Regulatory Improvement Plan)

  • 송승근
    • 한국정보통신학회논문지
    • /
    • 제22권12호
    • /
    • pp.1653-1658
    • /
    • 2018
  • 본 연구의 목적은 VR 영업장에서 발생된 규제 개선을 위해 국내 VR 테마파크 규제 개선 사례를 분석하고 법적 분쟁이 된 지점을 확인하여 이에 대한 해결안을 제시하고자 한다. 분석결과, 유원시설업에서 단일공간에 VR 시뮬레이터와 VR 게임이 동시에 설치될 경우 다중이용업소법에 따라 공간을 구획해야 하는 문제가 발생한다는 것을 발견하였다. 그 해결책으로 유원시설업에 게임산업법 적용을 받는 청소년 게임장 또는 PC 방의 일정 면적에서 운영할 수 있도록 관광진흥법 시행규칙을 개정해야 하며 다중이용업소법에서도 칸막이 같은 공간 구획을 하지 않는 법령 개정도 동시에 진행해야한다. 이는 업종별 공간구획을 제거함으로써 제한된 공간 내에서 적용하던 안전기준을 통합된 안전 기준으로 총괄 관리함으로써 훨씬 효율적이고 안전한 대안을 마련한 것이다. 이는 기타유원시설업과 같은 소규모의 유원시설업에도 VR 시뮬레이터와 VR 게임이 동일 영업장에서 운영될 수 있는 법률 개정이다. 본 규제개선안은 소규모의 VR 테마파크 활성화에도 도움을 줄 것으로 기대된다.

패션 버티컬 플랫폼 개인화 추천시스템의 사용자 경험에 관한 연구 -자기조절초점의 조절효과- (Study on User Experience of Personalized Recommendation Systems of Fashion Vertical Platforms -The Regulation Effect of Self-Regulatory Focus-)

  • 박민지;박현희;구양숙
    • 한국의류학회지
    • /
    • 제47권4호
    • /
    • pp.711-728
    • /
    • 2023
  • This study aims to validate the user experience associated with the personalized recommendation systems of fashion vertical platforms. The investigation focused on women aged 18 to 30 with prior experience using personalized fashion recommendation systems. The collected data were analyzed using SPSS 26.0 and AMOS 26.0, and the outcomes can be summarized as follows. Firstly, the diversity and usefulness of information quality exerted a positive effect on use satisfaction. Secondly, the affirmative impact of the reliability of system quality on user satisfaction was established, although stability was not confirmed. Thirdly, the study identified a favorable connection between ease-of-use of service quality and user satisfaction, while the influence of tangibles was unsubstantiated. Fourthly, the degree of self-reference was found to have a positive effect on user satisfaction. Fifthly, a constructive relationship emerged between user satisfaction and both continuous-use intention and recommendation intention. Lastly, there was a significant difference in the magnitude of the effect of ease-of-use on satisfaction according to self-regulatory focus. The findings of this study hold the potential to enhance the explanatory and predictive power of the field of consumer behavior within the novel shopping landscape of fashion vertical platforms.

금융기관 정보보호업무의 적정인력 산정에 대한 연구 (A Study of Proper Workforce Calculation on the Each Information Security Work in the Financial Institutions)

  • 박재영;김인석
    • 정보보호학회논문지
    • /
    • 제27권3호
    • /
    • pp.653-671
    • /
    • 2017
  • 현재 대부분의 금융기관이 정보보호인력 산정 시, 금융회사의 규모 및 정보보호업무 영역별 특성을 고려하지 않고, 일률적으로 전자금융감독규정에서 정한 총 IT 인력 수 대비 정보보호인력 비율(5%)만 준수하고 있다. 또한, 정보보호 인력이 여러 업무를 겸직함으로써 본연의 업무 소홀로 인한 리스크가 확대되고 있는 상황이다. 본 연구에서는 금융회사의 규모 및 각 정보보호업무의 특성을 고려한 필요 인력 수를 산정하여 체계적인 정보보호조직을 구성함으로써 금융 보안사고에 보다 효율적으로 대응할 수 있는 방안을 제시하고자 한다.

The Features of Restricted Access to Information at European and East Asian Libraries

  • Makhotina, Natalya;Pshenichnaya, Evgeniya
    • Journal of Information Science Theory and Practice
    • /
    • 제9권3호
    • /
    • pp.31-41
    • /
    • 2021
  • The growing number of threats to society through the uncontrolled distribution of information is forcing library communities in many countries to reconsider their views on free access to collections. Based on the content of numerous documents of international importance, it can be concluded that in any democratic country access to information is one of the most important human rights, along with the right to life, liberty, and security of person. However, the state has the right to restrict citizens' access to information within the framework of existing legislation. Constantly, restrictions on access to information are established in order to protect the ethical foundations of the constitutional order, morality, health, rights, and legitimate interests of others, to ensure the country's defense and state security. It goes without saying that each country has the right to independently decide where the boundaries lie between permitted and prohibited information, including printed information, contained in library collections. This article describes three levels of access restriction: foreign, state, and regional. The authors have analyzed the legal and regulatory documents that govern libraries, as well as the reasons and methods of limitation. A comparative analysis of the restriction of access to information in the countries of Europe and Asia is presented.

IPTV 개념을 이용한 학내 디지털 방송시스템 및 통합관리 시스템 연구 - 학교 통합방송시스템 운용소프트웨어 연구- (A study on the Broadcasting Systems and Digital Convergence Systems Based on the IPTV Concepts in the Educational Environment)

  • 신현택;이동훈;이덕진;현득창
    • 한국산업융합학회 논문집
    • /
    • 제14권4호
    • /
    • pp.135-142
    • /
    • 2011
  • Convergence between telecom and broadcasting is today a worldwide phenomenon. Diverse services like VoD, mobile broadcasting, IPTV and interactive services have already made their market debut or are currently being commercialized. Regulatory systems are also being revised to appropriately regulate this new breed of services. We propose the new model of educational broadcasting system using the internet network, it is not different conventional coaxial cable methods. Especially, we design the multicast method of the network using the limited channel and resource, propose the method of intercommunication in the school between the broadcasting system and database system.