• Korea Trade Review
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• v.41 no.1
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• pp.187-213
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• 2016

Trans-Pacific Partnership Agreement and Trans-Atlantic Trade and Partnership Agreement introduce "regulatory coherence." Regulatory coherence refers to "the use of good regulatory practices in the process of planning, designing, issuing, implementing and reviewing regulatory measures in order to facilitate achievement of domestic policy objectives, and in efforts across governments to enhance regulatory cooperation in order to further those objectives and promote international trade and investment, economic growth and employment." This paper traces ideas dealing with regulatory reform and regulatory transparency as discussed in OECD, APEC and selected WTO agreements, examines the text of the regulatory coherence chapter of TPP and TTIP, then examines the regulatory reform system of Korea to see whether Korea satisfies the conditions set forth in the regulatory coherence chapter of TPP. The paper concludes that the Korean regulatory reform system mostly satisfies the requirements of the TPP chapter on regulatory coherence, but some additional procedural reforms are needed for laws proposed by National Assemblymen, and regional laws proposed by regional governments. Finally, the paper notes that the Korean government has been mis-translating regulatory coherence as regulatory convergence, which is a separate idea, and the government should correct its error as soon as possible.

• Journal of Life Science
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• v.19 no.8
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• pp.1159-1163
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• 2009

It has been postulated that endoplasmic (ER) stress is involved in the development of several diseases. However, the detailed molecular mechanisms have not been fully understood. Therefore, we characterized a genetic network of genes induced by ER stress using cDNA microarray and gene set expression coherence analysis (GSECA), and identified gene function as well as several transcription regulators associated with ER stress. We analyzed time-dependent gene expression profiles in thapsigargin-treated Sk-Hep1 using an oligonucleotide expression chip, and then selected functional gene sets with significantly high expression coherence which was processed into functional clusters according to the expression similarities. The functions related to sugar binding, lysosome, ribosomal protein, ER lumen, and ER to golgi transport increased, whereas the functions with mRNA processing, DNA replication, DNA repair, cell cycle, electron transport chain and helicase activity decreased. Furthermore, functional clusters were investigated for the enrichment of regulatory motifs using GSECA, and several transcriptional regulators associated with regulation of ER-induced gene expression were found.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.728-742
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• 2021

The purpose of this study was to explore the dysfunctional effects of job crafting by examining (1) the sequential dual mediating effect of work-related sense of coherence (Work-SoC) and job strain on the relationship between two dimensions of job crafting (i.e., promotion focus & prevention focus) and turnover intentions, and (2) the moderating effect of supervisor support in the relationship between each focus and Work-SoC. A total of 293 employees working at various companies in Korea participated in an online survey. The results showed that promotion-focus job crafting had a direct negative effect on turnover intention, while prevention-focus job crafting had a direct positive effect. Both promotion- and prevention-focus job crafting also had indirect effects on turnover intention by partially mediating Work-SoC and job strain. Supervisor support had a moderating effect on the relationship between prevention-focus job crafting and Work-SoC, weakening the negative effect of prevention focus on Work-SoC. The implications and future directions are discussed on the basis of the results.