• 제목/요약/키워드: Regulation Development

검색결과 2,827건 처리시간 0.031초

Effect of Different Kinds of Ginseng Saponin on the Immunity of Young and Old Mice

  • Huo, Yu-Shu;Liu, Ping;Masanori Utsuyama;Hirokawa Katuoku
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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    • pp.281-288
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    • 1998
  • Ginseng saponin from different part of Ginseng and 7 kinds of ginsenosides effect on immnotuncition of young and old mice. There have up-regulation effect in vivo and in vitro experiments for low function of old mice, but not up-regulation effect at normal immuno-function of young mice. That means "Adaptogens" of Ginseng saponin. Not appositions effect at Pg1 and Rb1 and have find, that effect relations with molecular weight of ginsenosides.senosides.

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안전성 확보를 위한 전기안전관리기준의 재설정에 관한 연구 (A Study on the Reconfiguration in the Regulation of Electric Safety Management for the Guarantee of Safety)

  • 정재희
    • 한국안전학회지
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    • 제24권6호
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    • pp.45-49
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    • 2009
  • This study is to prepare a reasonable basis for the improvement of the electrical safety management regulation. The standards in domestic and foreign countries for the application of new and renewable energy facilities and other devices are analyzed. Other regulations excluding the electrical safety fields and wide surveys are also carried out. Consequently, it is asked that the classification between normal and self electrical facilities should be clear and deregulation for small businesses has to be followed. This study is showed that standards investigates of receiving equipment below 600V above 75kW, eletrical safety manager employment of manufacturing industry and Mid-night electric power. And, it is showed that consignment permission and Consignment inspection periodic relaxation about wind development equipment below 1,000kW, consignment of Technical Development equipment for new and renewable energy below 250kW.

The Impact of Organokines on Insulin Resistance, Inflammation, and Atherosclerosis

  • Choi, Kyung Mook
    • Endocrinology and Metabolism
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    • 제31권1호
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    • pp.1-6
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    • 2016
  • Immoderate energy intake, a sedentary lifestyle, and aging have contributed to the increased prevalence of obesity, sarcopenia, metabolic syndrome, type 2 diabetes, and cardiovascular disease. There is an urgent need for the development of novel pharmacological interventions that can target excessive fat accumulation and decreased muscle mass and/or strength. Adipokines, bioactive molecules derived from adipose tissue, are involved in the regulation of appetite and satiety, inflammation, energy expenditure, insulin resistance and secretion, glucose and lipid metabolism, and atherosclerosis. Recently, there is emerging evidence that skeletal muscle and the liver also function as endocrine organs that secrete myokines and hepatokines, respectively. Novel discoveries and research into these organokines (adipokines, myokines, and hepatokines) may lead to the development of promising biomarkers and therapeutics for cardiometabolic disease. In this review, I summarize recent data on these organokines and focus on the role of adipokines, myokines, and hepatokines in the regulation of insulin resistance, inflammation, and atherosclerosis.

IL-17 and IL-21: Their Immunobiology and Therapeutic Potentials

  • Choong-Hyun Koh;Byung-Seok Kim;Chang-Yuil Kang;Yeonseok Chung;Hyungseok Seo
    • IMMUNE NETWORK
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    • 제24권1호
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    • pp.2.1-2.24
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    • 2024
  • Studies over the last 2 decades have identified IL-17 and IL-21 as key cytokines in the modulation of a wide range of immune responses. IL-17 serves as a critical defender against bacterial and fungal pathogens, while maintaining symbiotic relationships with commensal microbiota. However, alterations in its levels can lead to chronic inflammation and autoimmunity. IL-21, on the other hand, bridges the adaptive and innate immune responses, and its imbalance is implicated in autoimmune diseases and cancer, highlighting its important role in both health and disease. Delving into the intricacies of these cytokines not only opens new avenues for understanding the immune system, but also promises innovative advances in the development of therapeutic strategies for numerous diseases. In this review, we will discuss an updated view of the immunobiology and therapeutic potential of IL-17 and IL-21.

산지개발의 공간분포와 산림훼손 (Forest Degradation and Spatial Distribution of Forest Land Development)

  • 유재심;최원태;이상혁;최재용
    • 한국환경복원기술학회지
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    • 제19권6호
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    • pp.101-110
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    • 2016
  • Development activities in forest areas are analysed based on degree of slope, altitude, land cover, and prefectures in order to improve the capacity of existing regulations of 'feasibility of forest land conversion' and 'assessment of forest land characteristics' in this research. 959 land based developments between year 2007 and 2013 have been analysed. A development site includes over 50% of forest is categorized as a forest type, degree of slope is steeper than $8.5^{\circ}$ as mountain type, and a development included in the both categories as combined type. Distribution characteristics of the above three types are analysed by development categories and regions adopting Relative Mountain Development Index(RMDI). In results, 44.94% of total development activities have been carried out in Gyeongsang Do in order of urban development, industrial complex, sports facilities, and soil and stone collection quarrying. Developments less than $0.3km^2$ which are exempt from the feasibility of forest land conversion regulation consist 86 cases of forest type, 78 cases in mountain type, and 78 cases in combined type. SAI by slope range showed the highest value of 1.55 in less than $5^{\circ}$ and the lowest value of 0.69 between $20^{\circ}-25^{\circ}$. RMDI value in Gyeongsang Do where mountain ratio is 67.05% appeared 1.17, which is 5 times more than Gangwon Do where mountain area ratio is 81.30%, and 2 times more than Chungchung Do where mountain area ratio is 51.24%. Development activities in forestland in Korea showed unequal distributions and 26% of those developments were not subjected to the feasibility of forest land conversion regulation.

U-중차량 무인과적단속시스템 구축방안에 대한 연구 (A Study on Development of U-Manless Overload Regulation System)

  • 조병완;김도근;최해윤;박정훈;윤석민
    • 한국전산구조공학회논문집
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    • 제20권3호
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    • pp.387-392
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    • 2007
  • 과적차량은 도로와 교량의 내구성 감소에 가장 큰 위험요소 중 하나여서 지금까지 이런 문제를 제한하기 위해 과적차량에 대한 단속이 실시되어 왔다. 그러나 기존의 시스템은 많은 문제점을 내포하고 있어서 이에 대한 대처방안이 요구되고 있다. 이러한 이유로 본 논문에서는 기존 문제점 해결과 u-ITS의 구축을 위해 무인화, 무선화 기반의 U-중차량 무인과적 단속시스템 구축방안을 제시하며 이를 위해, 시스템 구성방법, USN의 적용, 시스템 제어부와 WCDMA/HSDPA의 설계에 대해 연구하고 WIM 센서의 성능에 대해 검증하였다.

자녀의 정서표현에 대한 부모의 태도, 남녀 아동의 정서조절 능력 및 사회적 능력간의 관계 (Social Competence : Its Relationship to Parents' Attitudes toward Children's Expressiveness and Emotion Regulation)

  • 김은경;도현심;김민정;박보경
    • 아동학회지
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    • 제28권3호
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    • pp.115-131
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    • 2007
  • The 305 fathers and mothers of 4- to 5-year-old children and their teachers participating in this study responded to three kinds of questionnaires. Findings were that (1) fathers reported greater control of their sons' negative expressiveness; mothers reported greater control of their sons' positive expressiveness. Mothers perceived daughters more likely to regulate their emotions than their sons and teachers perceived girls more likely to be well-adjusted interpersonally than boys. (2) Fathers who reported higher control of their sons' negative expressiveness had sons with higher popularity/leadership; mothers who reported higher control of sons' negative expressiveness had sons with lower interpersonal adjustment. (3) Boys with higher emotion regulation showed higher interpersonal adjustment and popularity/leadership. (4) Mothers' control of boys' negative expressiveness influenced boys' interpersonal adjustment, and boys' emotion regulation and fathers' control of boys' negative expressiveness influenced boys' popularity/leadership.

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환경소음·진동 관리체계 개선전략에 관한 연구 (A Study on the Improvement Strategy of Environmental Noise and Vibration Administration System)

  • 박영민;이내현;선우영
    • 환경영향평가
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    • 제10권4호
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    • pp.305-317
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    • 2001
  • Effects on increased noise influenced residents on the urban areas as well as the rural areas because of rapidly increasing traffic volume and newly-constructed road. The object of this study is to better establish environmental policy for the year 2000s through analyzing current environment administration system in the field of noise and vibration. Noise and vibration administration system in Korea is composed of various standards in areas of noise environment, traffic noise regulation, living noise regulation, factory noise and vibration regulation, and aircraft noise regulation. Furthermore, there exists environment noise and vibration monitoring networking system. This study is to improve noise and vibration administration system through analyzing present condition and problems. This study suggests improved noise and vibration administration system by achieving four steps ; 1) goal establishment in noise and vibration administration system; 2) development of reduction mitigation method; 3) estimation of reduction mitigation method; 4) establishment of enforcement method. Proposed "Noise and Vibration Policy Committee" should be established to harmonize noise and vibration policy on scientific basis for the $21^{st}$ century.

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분산형전원이 도입된 배전계통의 최적전압조정 방안에 관한 연구 (A Study on the Optimal Voltage Regulation in Distribution Systems with Dispersed Generation Systems)

  • 김미영;오용택;안재윤;김재언;김응상;노대석
    • 대한전기학회논문지:전력기술부문A
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    • 제54권5호
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    • pp.251-258
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    • 2005
  • Recently, the domestic and foreign power trends are the supply of high quality power and environment conservation technology based on the new energies development. So, the dispersed generation systems, such as photovoltaic, fuel cell, and battery are to be introduced in distribution systems. According to the situation change, power of high Quality and reliability are required in distribution systems with dispersed generation. Up to now, the voltage in distribution systems are regulated by ULTC of substation and pole transformer of primary feeders. These days, Step Voltage Regulator(SVR) is getting established at distribution feeders to regulate effectively voltage of primary ffeders that voltage drop exceeds $5\%$. But, because SVR is operated independently with ULTC of substation, SVR can not take play to its full effectivity. Under these circumstances, in order to deliver suitable voltages to as many customers as possible, new optimal voltage regulation algorithms are required in distribution system. So, this paper presents optimal voltage regulation algorithm to regulate voltage effectively for ULTC and SVR in distribution systems with dispersed generation systems.

Brassinosteroids-mediated regulation of ABI3 is involved in high-temperature induced early flowering in plants

  • Hong, Jeongeui;Sung, Jwakyung;Ryu, Hojin
    • Journal of Plant Biotechnology
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    • 제45권2호
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    • pp.83-89
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    • 2018
  • The interplay of plant hormones is one of the essential mechanisms for plant growth and development. A recent study reported that Brassinosteroids (BR) and ABSCISIC ACID (ABA) interact antagonistically in early seedling developments through the BR-mediated epigenetic repression of ABSCISIC ACID-INSENSITIVE 3 (ABI3). However, the other physiological roles of the BR-mediated regulation of ABI3 and ABA responses beyond early seedling developments remain largely unknown. Here, we showed that the activation of BR signaling by high temperatures promotes flowering time through the suppression of ABI3 expressions. Elevated ambient temperature induced early flowering in wild type Col-0 plants, but not in BR-defective bri1-116 mutant plants. Conversely, a hyper BR biosynthetic dwf4-D mutant displayed more sensitive thermomorphic long shoot elongation and early flowering. Both expression patterns and physiological responses supported the biological roles of ABI3 in the regulation of floral transition and reproduction under high temperature conditions. Finally, we confirmed that the lowered expressions of the transcript and protein levels of ABI3 brought on by elevated temperature were correlated with warmth-induced early flowering phenotypes. In conclusion, our data suggest that the BR- and warmth-mediated regulation of ABI3 are important in thermomorphic reproductive phase transitions in plants.