• Title/Summary/Keyword: Regional Regulation

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Prevention of Hyperuricemia by Clerodendrum trichotomum Leaf Extract in Potassium Oxonate-Induced Mice

  • Jang, Mi Gyeong;Song, Hana;Kim, Ji Hye;Oh, Jung Min;Park, Jung Young;Ko, Hee Chul;Hur, Sung-Pyo;Kim, Se-Jae
    • Development and Reproduction
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    • v.24 no.2
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    • pp.89-100
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    • 2020
  • Clerodendrum trichotomum is a folk medicine exhibiting anti-hypertension, anti-arthritis, and anti-rheumatism properties. However, little is known about whether the material might prevent hyperuricemia and associated inflammation. In this study, we explored whether C. trichotomum leaf extract (CTE) prevented hyperuricemia induced by potassium oxonate (PO) in mice. CTE (400 mg/kg body weight) significantly reduced the serum uric acid (UA), blood urea nitrogen (BUN), and serum creatinine levels and increased urine UA and creatinine levels. CTE ameliorated PO-induced inflammation and apoptosis by reducing the levels of relevant proteins in kidney tissues. Also, CTE ameliorated both UA-induced inflammatory response in RAW 263.7 cells and UA-induced cytotoxicity in HK-2 cells. In addition, liver transcriptome analysis showed that CTE enriched mainly the genes for mediating positive regulation of MAPK cascade and apoptotic signaling pathways. Together, the results show that CTE effectively prevents hyperuricemia and associated inflammation in PO-induced mice.

Autonomous Decentralized Coordination Control Algorithm for Keeping the voltage of Micro-grid within a Proper Level (Micro-grid의 적정전압유지를 위한 자율분산 협조운용 제어알고리즘)

  • Kim, Jae-Eon;Shin, Seong-Soo;Rho, Dae-Seok;Yoon, Gi-Gab
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.1
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    • pp.81-90
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    • 2009
  • Interconnection of DG(Distributed Generation) into distribution systems and power quality are frequent subjects of discussion by distribution companies, regional electricity utilities and industrial customers. This situation makes many experts estimate a next generation of distribution systems which is composed of some micro-grids. But the proposed micor-grid is only mentioned as a small network with DG's, power quality compensators, communication and control equipments. In this paper, a decentralized coordination control algorithm of micro-grid which is able to supply the electric power with high reliability and quality, are proposed.

The Role of IMO for the Eradication of IUU Fishing (국제해사기구의 IUU 어업 퇴치 기여 및 전망)

  • Kim, Jung-Eun
    • The Journal of Fisheries Business Administration
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    • v.46 no.3
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    • pp.15-29
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    • 2015
  • The illegal, unreported and unregulated fishing can be properly regulated only if fishing activities, transhipment and landing of illegally caught fish, and processing of fish at sea involved in it are integrally managed. To do this, flag States, port States, coastal States, market States and relevant regional fisheries management organizations shall closely cooperate. In addition, fishing boats involved in IUU fishing often ignore requirements of safety of navigation so that they could be exposed to more causes of incidents and could have less chances to be rescued. Then, it seems to be necessary for the regulation on IUU fishing to include a certain consideration of strengthening safety of those ships. International Maritime Organization(IMO) has developed and implemented international rules for the safety of shipping. IMO has cooperated with Food and Agricultural Organization on IUU fishing since 2000 and the third joint meeting is scheduled in November 2015. This paper reviews the recommendations adopted in the previous meetings, and the measures actually taken as a result of the cooperation and, in particular, focus on the additional roles of IMO for the eradication of the IUU fishing.

Thinking about the training system of R.O.K. reserved force in the future (미래형 예비군 훈련체제 정립에 관한 연구)

  • Jeong, Won-Young
    • Journal of National Security and Military Science
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    • s.5
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    • pp.47-85
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    • 2007
  • Reserved force's training(RFT) is undoubtedly the critical component to increase the national capability in case of emergency. It is because RFT plays an important role in maintaining the peace for the Korean peninsula as the key deterrence force power for more than 40 years. Considering the reserved force reform linked with the goal and the plan of Korean Defense Reform 2020', we can expect the utility of the reserved force as the potential combat power to make national defense resources more efficient and useful. In that sense, this study suggests some solutions to promote the reserved force's competency to demonstrate the ROK Armed Force's combat power as the equivalent partner with the active force as well as the future deterrence power. This study also analyzes the present training system including law and regulation, identifies some implications through the literature review, and designs the future ROK reserved force's training system by extracting new variables forecasting the future environment for national defense. In addition, this study includes its concerned systems generally without limiting the scope into the reserved force. Therefore we try to seek to prepare for mobilization readiness and to promote regional hometown defense capability in order to cope with the enemy's threat in case of emergency.

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A Curriculum Development for Korean Occupational Health Nurse Specialist Program (산업전문간호사 교육과정 운영방안에 관한 연구)

  • June, Kyung Ja
    • Korean Journal of Occupational Health Nursing
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    • v.14 no.1
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    • pp.34-43
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    • 2005
  • Purpose: The purpose of this study is to develop the curriculum model for occupational health nurse specialist in Korea. Method: Internet searching was conducted to analyze the type of master program for occupational health nurses in the U. S. To identify the importance of occupational health nurse specialist (OHNS)'s role, self-administrative questionnaire survey was done to335 occupational health nurses through postal mail and continuing education in 2003. SPSSWIN 10.0 was used for data analysis. Results: In the U. S., two main types of nurse practitioner program and nurse manager program are separately operated for occupational health nurses as master level. Under the governmental support, geographical and financial barrier can be decreased through the distance learning and the appointment of regional ERC. Most occupational health nurses recognized importantly the role of OHNS as direct care provider, educator, consultant, and manager. Conclusion: It is recommended that the job standard for OHNS needs to be developed, and regulation has to be changed for the diverse curriculum based on the need of occupational health nurses, and governmental support must be strengthened for occupational health nurses to apply more easily to the program.

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The study of the law system for constructing a Home-Network at the environment of apartment houses (공동주택 환경에서의 홈네트워크 구축을 위한 법제도 연구)

  • Lim, Sang-Chul;Kim, Sun-Hyung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.5
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    • pp.801-808
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    • 2008
  • As Home Network facilities are more enlarging on the basis of a Certification system and U-City by a different operators and regional groups. In this paper, describer to the status of it's installation and promotion and arrange it's general idea and law system concept. Also, draw operation system's problems and present counterproposal through analyzing an application basis of the law systems and information-communication technical standards such as construction law, housing law, and regulation to the housing construction standard. etc. We suggest an change necessity of the law system that home network can get ready for safely, facilities, comfortability of the user's convenience.

An Empirical Research on Current Status and Developmental Countermeasures of Language Services Industry in China

  • Tong, Ying;Zhang, Mengze;Wu, Chanti;Bae, Ki-Hyung
    • International Journal of Contents
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    • v.15 no.2
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    • pp.44-52
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    • 2019
  • This paper uses Delphi Method and statistics provided by the State Administration of Market Regulation of China, attempts to develop the scale index of language service industry in China. Coupled with practical investigation and theoretical framework of SCP paradigm, a deep analysis on market behavior, market structure, and market performance of the industry have been explored. First, the study indicates that the scale index of Chinese language services industry has experienced an upward trend from 10.481million RMB in 2008 to 351.403 million RMB in 2017. Second, majority of language services enterprises are situated in Chinese coastal provinces and there are variations in demand for language services. Third, the standardization of language services are minimal while most of the talents involve a single discipline background. Fourth, most enterprises utilize language tools while there is lack of technological innovation for utilization of language resources and enhancement of service quality. The author mainly suggests four strategies which include: cultivating multilingual services, strengthening the development of industrial informatization and technical innovation, and optimizing the industrial talents structure while also adjusting for industrial distribution and regional coordination, which propose the meaningful implications for the development of language service industry in China.

A Characteristics of Scenic Maintenance Regime with Integral Planning in Mojiko-Retro District (모지코 레트로지구의 경관관리제도와 중점지구 통합 계획적 특성)

  • Kim, Do-Yeon;Yoo, Jae-Woo
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.35 no.1
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    • pp.63-72
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    • 2019
  • The purpose of this study is that investigated the characteristics of integral planning related factors using the history and culture of Mojiko. It is a small city that has been urbanized after the opening of the port for logistics transportation in the modern period of Japan. As the function of the logistics city, which is the factor of the expansion of the town, declined, Mojiko applied the retro concept to the harbor which has lost its popularity due to the regional characteristics of the city to increase and revitalize local visits. Mojiko has steadily promoted the retro style of landscape and town development over 30 years, focusing on 18 Historical buildings and modern infrastructure. We analyzed characteristics of integrated urban planning include the regulation, landscape institution. Moreover, we suggest the result of the designation process of a core scenery maintenance district and the components of the plan after the designation analysis and provide essential data for revitalizing the field based on the historic city for the cultural establishment and beautiful town in the future. And deliver vital data to reviving the area based on the historical city culture establishment and beautiful town in the future.

Anti-Oxidative and Anti-Inflammatory Activities of Euptelea Pleiosperma Ethanol Extract (Euptelea pleiosperma 에탄올 추출물의 항산화 및 항염증 활성)

  • Jin, Kyong-Suk;Park, Jung Ae;Lee, Ji Young;Kang, Ji Sook;Kwon, Hyun Ju;Kim, Byung Woo
    • Microbiology and Biotechnology Letters
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    • v.42 no.2
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    • pp.170-176
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    • 2014
  • In this study, the anti-oxidative and anti-inflammatory activities of Euptelea pleiosperma ethanol extract (EPEE) were evaluated using in vitro assays and cell culture model systems. EPEE possessed a more potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl than the ascorbic acid used as a positive control. EPEE effectively suppressed lipopolysaccharide (LPS), in addition to hydrogen peroxide induced reactive oxygen species on RAW 264.7 cells. Furthermore, EPEE induced the expression of the anti-oxidative enzyme heme oxygenase 1 (HO-1) and its upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), dose and time dependently. The modulation of HO-1 and Nrf2 expression might be regulated by mitogen-activated protein kinases and phosphatidyl inositol 3 kinase/Akt as their upstream signaling pathways. On the other hand, EPEE inhibited LPS induced nitric oxide (NO) formation without cytotoxicity. Suppression of NO formation was the result of the down regulation of inducible NO synthase (iNOS) by EPEE. Suppression of NO and iNOS by EPEE may be modulated by their upstream transcription factor, nuclear factor ${\kappa}B$, and AP-1 pathways. Taken together, these results provide important new insights into E. pleiosperma, namely that it possesses anti-oxidative and anti-inflammatory activities, indicating that it could be utilized as a promising material in the field of nutraceuticals.

Present Status on the Pesticide Residue Monitoring Program of South Korea and Its Improvement (한국의 잔류농약 모니터링 프로그램 현황과 개선)

  • Lee, Mi-Gyung
    • Journal of Food Hygiene and Safety
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    • v.34 no.3
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    • pp.219-226
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    • 2019
  • This study was conducted to understand the overall status of the monitoring program for pesticide residues in foods of South Korea. Further propositions for its improvement were made, and from this study, the status on this program can be summarized as follows. In South Korea, the Ministry of Food and Drug Safety (MFDS) is responsible for overall control of pesticide residue monitoring. Depending on the time of monitoring (sampling at distribution or production step), the government agency responsible for monitoring is different: MFDS, Regional Offices of Food and Drug Safety and local governments are responsible for monitoring of foods at the distribution step, while the National Agricultural Products Quality Management Service (NAQS) and local governments are responsible for monitoring of foods in the production step (partially at sale and distribution steps). According to purpose of monitoring, domestic monitoring programs could be divided into two types: MFDS's "Residue Survey" and NAQS's "National Residue Survey" are conducted mainly for risk assessment purposes and various monitoring programs by the Regional Offices of Food and Drug Safety and local governments are conducted mainly for regulation purposes. For imported foods, monitoring should be conducted at both steps of customs clearance and distribution: the MFDS and the Regional Offices of Food and Drug Safety are responsible for the former, and for the latter, local governments are also responsible. However, it appeared that systematic and consistent monitoring programs are not being conducted for imported foods at the distribution step. Based on the information described above and more detailed information included in this paper, the following proposals for improving the monitoring program were forwarded: i) further clarification of monitoring program purpose, ii) strengthening of the monitoring program for imported foods, iii) providing the public with monitoring results by publication of an annual report and database. It is thought that exhaustive review on the pesticide residue monitoring program and efforts for its improvement are needed in order to assure both food safety and the success of the recently begun positive list system (PLS).