• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.163-169
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• 2016

In Korea, prostate cancer accounted for generating growth rate second the following thyroid cancer, because of western dietary habits. Survival rate of prostate cancer after clinical behavior is changed depend on follow-up management. A telemedicine have been applied to replacement of medical specialist in rural area, and a quick reaction to emergency situation. Our study developed prostate 3-dimensional (3D) visualization program and designed prostate aftercare system architecture, called smart care, using a device that can access the Internet. Region of interest (ROI) in prostate was manually segmented by physicians and visualized to 3D objects and sent to PACS Server as DICOM images. So, medical personnel could confirm patients' data along with 3D images not only PACS system, but also portable device like a smart phone. As a result, we conducted the aftercare service to 98 patients and visualize 3D prostate images. 3D images had advantage to instinctively apprehend where lesion is and make patients to understand state of their disease easily. In the future, should conduct an aftercare service to more patients, and will obtain numerical index through follow-up study to an accurate analysis.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.6
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• pp.1183-1188
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• 2016

Kinect sensor version 2 is a kind of camera released by Microsoft as a computer vision and a natural user interface for game consoles like Xbox one. It allows acquiring color images, depth images, audio input and skeletal data with a high frame rate. In this paper, using depth image, we present a surveillance system of a certain area within Kinect's field of view. With computer vision library(Emgu CV), if an object is detected in the target area, it is tracked and kinect camera takes RGB image to send it in database server. Therefore, a mobile application on android platform was developed in order to notify the user that Kinect has sensed strange motion in the target region and display the RGB image of the scene. User gets the notification in real-time to react in the best way in the case of valuable things in monitored area or other cases related to a reserved zone.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.277-287
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• 2003

Acetolactate synthase (ALS, EC 4.1.3.18; also referred to as acetohydroxy acid synthase) catalyzes the first common step in the biosynthesis of valine, leucine, and isoleucine in microorganisms and plants. Recently X-ray structure of yeast ALS was available. Pair-wise alignment of yeast and tobacco ALS sequences revealed 63% sequence similarity. Using Deep View and automatic modeling on Swiss model server, we have generated reliable models of tobacco ALS based on yeast ALS template with a calculated pair-wise RMSD of 0.86 Angstrom. Functional roles of four residues located on the subunit interface (H142, El43, M350, and R376) were examined by site-directed mutagenesis. Seven mutants were generated and purified, of which three mutants (H142T, M350V, and R376F) were found to be inactivated under various assay conditions. The H142k mutant showed moderately altered kinetic properties. The E143A mutant increased 10-fold in K$_m$ value while other parameters remained unchanged. The M350C mutant was strongly resistant to three tested herbicides, while the R376k mutant can bind with herbicide carder at similar affinity to that of wild type enzyme, as determined by tryptophan quenching study. Except M350V mutant, all other mutants were ate to bind with cofactor FAD. Taken together, it is likely that residues H142 and E143 are located at the active site, while residues M350 and R376 are possibly located at the overlapping region of active site and herbicide binding site of the enzyme. Our data also allows us to hypothesize that the interaction between side chains of residues M350 and R376 are probably essential for the correct conformation of the active site. It remains to be elucidated that, whether the herbicide, upon binding with enzyme, inactivates the enzyme by causing change in the active site allosterically, which is unfavorable for catalytic activity.

• Interdisciplinary Bio Central
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• v.2 no.3
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• pp.8.1-8.5
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• 2010

Introduction: Recently identified human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Bioinformatics study of hABH2 and hABH3 had led to the discovery of a novel DNA repair mechanism. Very little is known about structure and function of hABH4, one of the members of this superfamily. Therefore, in present study we are intended to predict its structure and function through various bioinformatics tools. Materials and Methods: Modeling was done with modeler 9v7 to predict the 3D structure of the hABH4 protein. This model was validated with the program Procheck using Ramachandran plot statistics and was submitted to PMDB with ID PM0076284. The 3d2GO server was used to predict the functions. Residues at protein ligand and protein RNA binding sites were predicted with 3dLigandSite and KYG programs respectively. Results and Discussion: 3-D model of hABH4, ALKBH4.B99990003.pdb was predicted and evaluated. Validation result showed that 96.4 % residues lies in favored and additional allowed region of Ramachandran plot. Ligand binding residues prediction showed four Ligand clusters, having 24 ligands in cluster 1. Importantly, conserved pattern of Glu196-X-Pro198- Xn-His254 in the functional domain was detected. DNA and RNA binding sites were also predicted in the model. Conclusion and Prospects: The predicted and validated model of human homologue hABH4 resulted from this study may unveil the mechanism of DNA damage repair in human and accelerate the research on designing of appropriate inhibitors aiding in chemotherapy and cancer related diseases.

• Journal of Satellite, Information and Communications
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• v.12 no.1
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• pp.49-53
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• 2017

In this paper we present the combination of location based mobile advertisement services and dynamic digital signage markets has been developing recent days to provide consumer admired visual mobile advertisement on all kind transportation vehicles. In spite of that, the digital signage advertisement content management is still not that easy to manage the content dynamically as well operation is most time consuming to handle the contents dynamically in digital signage business. As location based services is most impactful service in shopping, the location responsive advertisement on vehicle signage will be most desirable mobile advertisement to help people migrate from one place to another place for travel or stay. This paper propose a mobile location responsive digital signage system for vehicles using the GPS and wireless infrastructure integrated with digital signage system. This proposed research use the centralized digital signage system architecture for the mobile advertisement application and this system can be expanded to different vehicles for digital advertisement including buses, trucks, train, air vehicle and any other form of mobile advertising vehicles. Also, this present an effective advertisement recommendation algorithm, by which the advertisement can be selected broadcasted for the right advertisement ventures more effectively as the service requested from advertiser. This paper present the emulated experimental result to evidence the proposed dynamic vehicle signage system performed better than compared with traditional signage random advertising. The emulated result proves that the advertisement recommendation algorithm can effectively works out the targeted key audiences in location responsive region the algorithm evaluated.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.5
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• pp.109-120
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• 2017

It is important to estimate objectively in the driving test. Especially, the driving test is examined by totally driving ability, rule observation and situational judgement. For this, a grading automation system for driving test was presented by using GPS, sensor data and equipment operation informations. This system is composed of vehicle mounted module, automatic grading terminal, data controller, data storage and processing server. The vehicle mounted module gathters sensor data in the car. The terminal performs automatic grading using the received sensor data according the driving test criterion. To overcome the misposition of vehicle in the map due to GPS error, we proposed the automatic grading system by map matching method, path deviation and return algorithm. In the experimental results, it was possible to grade automatically, display the right position of the car, and return to the right path under 10 seconds when the vehicle was out of the shadow region of the GPS. This system can be also applied to the driving education.

• KIPS Transactions on Computer and Communication Systems
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• v.2 no.7
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• pp.293-302
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• 2013

Home network providers have many worries about providing home network services with an expandable, reliable, flexible and low-cost structure according to the expanding market environment. The existing client-server system has various problems such as complexity and high costs in providing home network services. In this paper we propose the P2P-SIP structure. P2P communication terminal supporting access of distributed resources provides functions which the existing SIP-based network devices have. Because diverse terminals in a home network access through networks, also, partitioning network domains with home gateways to manage, and applying the network-based PMIPv6(Proxy Mobile IPv6) technology considering mobility of terminals would help to have a more efficient home network structure. Especially, the proposed P2P-SIP structure proves itself as a very efficient structure to have an outstanding expandability among different home networks in a region, and to reduce maintenance costs.

• The Plant Pathology Journal
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• v.36 no.6
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• pp.618-627
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• 2020

Although limited progress have been made about pathogen system of Hibiscus rosa-sinensis and Hibiscus latent Fort Pierce virus (HLFPV), interaction between plant host and pathogen remain largely unknown, which led to deficiency of effective measures to control disease of hibiscus plants caused by HLFPV. In this study, infection of HLFPV in Hibiscus rosa-sinensis was firstly confirmed for the first time by traditional electron microscopy, modern reverse transcription polymerase chain reaction and RNA-seq methods in China (HLFPV-Ch). Sequence properties analyzing suggested that the full-length sequences (6,465 nt) of HLFPV-Ch had a high sequence identity and a similar genomic structure with other tobamoviruses. It includes a 5'-terminal untranslated region (UTR), followed by four open reading frames encoding for a 128.5-kDa replicase, a 186.5-kDa polymerase, a 31-kDa movement protein, 17.6-kDa coat protein, and the last a 3'-terminal UTR. Furthermore, HLFPV-Ch-derived virus-derived siRNAs (vsiRNAs) ant its putative target genes, reported also for the first time, were identified and characterized from disease Hibiscus rosa-sinensis through sRNA-seq and Patmatch server to investigate the interaction in this pathogen systems. HLFPV-Ch-derived vsiRNAs demonstrated several general and specific characteristics. Gene Ontology classification revealed predicted target genes by vsiRNAs are involved in abroad range of cellular component, molecular function and biological processes. Taken together, for first time, our results certified the HLFPV infection in China and provide an insight into interaction between HLFPV and Hibiscus rosa-sinensis.

• Journal of the Institute of Convergence Signal Processing
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• v.13 no.2
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• pp.83-90
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• 2012

In this paper, an intelligent visual surveillance system based on a NIOS II embedded platform is implemented. By this time, embedded based visual surveillance systems were restricted for a special purpose because of high dependence upon hardware. In order to improve the restriction, we implement a flexible embedded platform, which is available for various purpose of applications. For high speed processing of software based programming, we improved performance of the system which is integrated the SOPC type of NIOS II embedded processor and image processing algorithms by using software programming and C2H(The Altera NIOS II C-To-Hardware(C2H) Acceleration Compiler) compiler in the core of the hardware platform. Then, we constructed a server system which globally manage some devices by the NIOS II embedded processor platform, and included the control function on networks to increase efficiency for user. We tested and evaluated our system at the designated region for visual surveillance.

• Journal of Industrial Convergence
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• v.21 no.2
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• pp.111-116
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• 2023

Recently, viral infectious diseases and new diseases are not limited to one region, but are spreading worldwide, causing serious economic and social damage. In addition, the development cycle of new diseases is shortening, and the rate of spread is accelerating. In order to prevent the spread of disease, passive forms of response after a disease outbreak, such as personal and regional quarantine and border closure, are prioritized. This type of response has many shortcomings as a fundamental response to preventing the spread of disease. Therefore, this study proposes a disease prevention monitoring system including new disease occurrence information. In this study, disease information and user information are collected through the establishment of the IoMT environment. Information collection using an agent collects and classifies data registered in the disease information server. In the IoMT environment, user data is collected, and whether the user is infected with a disease is evaluated and provided to the user. Through this study, individual disease symptom information can be provided and active countermeasures against the spread of disease can be provided.