• Title/Summary/Keyword: Refusal

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Role of Glutathione Redox System on the T-2 Toxin Tolerance of Pheasant (Phasianus colchicus)

  • Fernye, Csaba;Ancsin, Zsolt;Bocsai, Andrea;Balogh, Krisztian;Mezes, Miklos;Erdelyi, Marta
    • Toxicological Research
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    • v.34 no.3
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    • pp.249-257
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    • 2018
  • The purpose of the present study was to evaluate the effects of different dietary concentrations of T-2 toxin on blood plasma protein content, lipid peroxidation and glutathione redox system of pheasant (Phasianus colchicus). A total of 320 one-day-old female pheasants were randomly assigned to four treatment groups fed with a diet contaminated with different concentrations of T-2 toxin (control, 4 mg/kg, 8 mg/kg and 16 mg/kg). Birds were sacrificed at early (12, 24 and 72 hr) and late (1, 2 and 3 weeks) stages of the experiment to demonstrate the effect of T-2 toxin on lipid peroxidation and glutathione redox status in different tissues. Feed refusal and impaired growth were observed with dose dependent manner. Lipid-peroxidation was not induced in the liver, while the glutathione redox system was activated partly in the liver, but primarily in the blood plasma. Glutathione peroxidase activity has changed parallel with reduced glutathione concentration in all tissues. Based on our results, pheasants seem to have higher tolerance to T-2 toxin than other avian species, and glutathione redox system might contribute in some extent to this higher tolerance, in particular against free-radical mediated oxidative damage of tissues, such as liver.

The SAFE Management System Model Based on Context Automatic Awareness

  • Han, Kook-Hee;Liu, Yiwen;Kwon, Young-Jik;Kang, Byeong-Do
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2007.02a
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    • pp.87-96
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    • 2007
  • Ubiquitous is a Latin-derived word meaning "to exist at any time and place" like water or air. In computing, the word "ubiquitous" indicates an environment in which users have access to networks without any limitation regarding computer networks or places. Important issues in building Ubiquitous Korea (U-Korea) are the social problems appearing with a rapid increase in the old age population. Nowadays, with the rise of the nuclear family, the increase in the number of elderly people living alone, and the change in the status of women, both wives and husbands are employed outside the home, and the relatives who would be responsible for supporting the elderly sometimes are on long or short business trips, and it happens that old people can't be looked after. Therefore the government developed a wireless paging system for the sick, disabled, old and weak so that when an emergency happens, by just simply dialing 119, an emergency aid center could take prompt action. However, the present wireless paging systems composing the under-layer of the emergency aid information system have some problems, such as, a lack of reliability, problems among terminals, mobile transmitters and receiving terminals, the users' refusal to admit the need for the system and poor operational skills, administrators' perfunctory management and checks, etc. On account of these problems, the system efficiency has degraded and therefore a system upgrade is necessary. In this paper, we attempt to evaluate the newly implemented SAFE119 system, a new wireless paging system seeking to correct the problems of the current system.

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Forming Weighting Adjustment Cells for Unit-Nonresponse in Sample Surveys (표본조사에서 무응답 가중치 조정층 구성방법에 따른 효과)

  • Kim, Young-Won;Nam, Si-Ju
    • Communications for Statistical Applications and Methods
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    • v.16 no.1
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    • pp.103-113
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    • 2009
  • Weighting is a common form of unit nonresponse adjustment in sample surveys where entire questionnaires are missing due to noncontact or refusal to participate. A common approach computes the response weight as the inverse of the response rate within adjustment cells based on covariate information. In this paper, we consider the efficiency and robustness of nonresponse weight adjustment bated on the response propensity and predictive mean. In the simulation study based on 2000 Fishry Census in Korea, the root mean squared errors for assessing the various ways of forming nonresponse adjustment cell s are investigated. The simulation result suggest that the most important feature of variables for inclusion in weighting adjustment is that they are predictive of survey outcomes. Though useful, prediction of the propensity to response is a secondary. Also the result suggest that adjustment cells based on joint classification by the response propensity and predictor of the outcomes is productive.

Ink setting and back trap mottle

  • Kim, Byeong-Soo;Park, Jong-Ywal;Bousfield, Douglas W.
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2003.04a
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    • pp.70-79
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    • 2003
  • Paper coating can give smoothness surface and good printability to uncoated paper. Macro roughness of base paper would be decreasing its groove and grit in view of side. Nevertheless its improving effect for paper, some kind of problem is showing in the fine coated paper. Especially, back trap mottle is one of serious problems in printing with fine coated paper. Printers can not adjust conditions to overcome the problem. Also large amounts of paper can be rejected. There are many factors that influence back trap mottle. However it is not clear what the important parameters are in back trap mottle. Back trap mottle has some relationship with ink setting but good guidelines are not clear. Back trap mottle has been linked to non-uniform ink setting. We do not know how much variation in setting we can tolerate. Other mottle issues such as micro-picking and ink refusal are still common. This paper was prepared to identify correlation with ink setting and delta ink density obtained from experiment and then tried to find out some relationships with ink setting and back trap mottle. Basically fine calcium carbonate and ciay was used for main components and coarse calcium carbonate was mixed in two fine pigments to change its porosity and ink acceptance. Micro ink tack force at KRK printing tester was adapted to measure ink setting rate. KRK units were used for back trap mottle simulation and two printed samples were prepared to check delta ink density. Clay base coating has more fast ink setting time than calcium carbonate's though smoothness of clay was better than calcium carbonate. It could be explained by that clay has finer pore in its coating than calcium carbonate. DID(delta ink density) has shown a good correlation with ink setting time from micro ink tack. The total pore volume of coating layer did not match with ink setting and DID. From the results we might conclude coating that has fine pore size around 0.05 ${\mu}m$ can be exposed to high possibility of back trap mottle.

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Surgical Treatment of Primary Lung Cancer (원발성 폐암의 외과적 치료)

  • 곽문섭
    • Journal of Chest Surgery
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    • v.21 no.1
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    • pp.87-100
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    • 1988
  • The authors evaluated 200 cases of primary carcinoma of lung in terms of the cell type, operability, resectability and survival rate, that proved by histopathologic examination at the Dept. of Thoracic and Cardiovascular Surgery, Catholic Medical College during the period of 11 years from Jan., 1977 to Dec., 1987. The results are as follows; 1] The peak incidence was observed in the 7th decade of life [34%] and followed by 6th [30%] 8 5th decade [25%]. Male to female ratio was 3.4:1. 2] Histopathologic classifications were squamous cell carcinoma 48% [96 cases], adenocarcinoma 27% [34 cases], small cell carcinoma 13%[26 cases], ;bronchioloalveolar cell carcinoma 5% [10 cases], large cell carcinoma 4.5% [9 cases], adenosquamous cell carcinoma 1.5% [3 cases] and adenoalveolar cell carcinoma 0.5% [1 case]. 3] Among 200 cases of primary lung cancer, the operability was 47.5% [95 cases], refusal of operation 6.0% [12 cases] and inoperability 46.5% [93 cases]. 4] Ninety five cases [47.5%] were operated. Of these, post-surgical stage I was 18.9% [18 cases], stage II 24.2% [23 cases] and stage III 56.8% [54 cases]. Among 54 cases of stage III, 32 cases were unresectable, while 22 cases were resectable. Consequently, the resectability was 31.5% [63 cases] from the total numbers of 200 cases, and the resectability for the operable 95 cases was 66.3% [63 cases]. 5] Surgical complications were empyema with bronchopleural fistula [4 cases], G-I bleeding [1 case], tedious pleural effusion [1 case] and acute respiratory insufficiency [1 case]. Operative mortality was 3.2% [2 cases], which caused by massive G-I bleeding [1 case] and respiratory insufficiency [1 case]. 6] On the long term follow-up of resectable 63 cases, overall 3 year survival rate was 35%, 5 year 22% and 9 year 2%. Five year survival rate was 39% in stage l, 30% in stage II and 0% in stage III. As for the cell types, the higher 5 year survival rate was observed in resectable squamous cell carcinoma [35%] as compared to adenocarcinoma [15%], alveolar cell carcinoma [14%], small cell carcinoma [0%] and large cell carcinoma [0%].

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A Study for the Development of a School-based Health Education of AIDS (AIDS의 학교 보건교육 도입에 관한 연구)

  • Kim, Hyeon Suk
    • Journal of the Korean Society of School Health
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    • v.9 no.2
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    • pp.249-266
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    • 1996
  • AIDS and the spectrum of Human Immunodeficiency Virus(HIV) infections present a monumental challenge to the health of the Korean public. In response to this special challenge, I think public education and voluntary behavior changes are the most effective measures to fight the spread of the disease. Adolescents represent a critical risk group for prevention and intervention programming. Research indicates sexually active adolescents, homosexual contact, illicit drug use are an gradually increasing. These characteristically adolescent risk-taking behaviors suggest the need for schools and communities to mobilize intervention strategies. Schools are highly efficient ways to reach a majority of young people in Korea with HIV prevention programs. These programs include substantial attention to sexual and drug use behaviors with the long term objective of a multidimensional school health program. Information resulting from risk behavior surveillance activities and guidance on school health curricula is particularly useful. What is needed for adolescents is a revamping of education to give students the critical thinking and analytic skills that allow them to apply knowledge, make decisions, and think independently. The best HIV preventive education provides young people with opportunities to learn and practice just those skills. In the early stages of HIV education were focused solely on information. Providing information is easy but unfortunately, behavior change is not that simple to activate. Information must be combined with values exploration and skilly building, including responsible decision making, negotiation, refusal, and critical thinking skills. The same knowledge, attitudes and skills needed for effective HIV prevention also prevent or reduce other risks, including other sexually transmitted diseases, unwanted pregnancies, and alcohol or other drug use. The role of other youth serving organizations in HIV prevention is also important: parental and youth involvement is needed; it's important to presidential and governament leadership is essential to prevention education; promote integrated adolescent programs, to enhance health and education sector collaboration; and of course, we need to expand research on adolescent health and engage the media in health promotion. Among these changes, a school-based systematic health education of AIDS is certainly one of the essentials.

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A Level Group Streaming Technique for Interactive VOD based on P2P (P2P 기반 Interactive VOD를 위한 레벨 그룹 스트리밍 기법)

  • Kim, Jong-Gyung
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.11C
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    • pp.955-962
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    • 2008
  • Multicast Strategy is one of the cost-saving methods in the large scale VOD environment. However, it does involve complicated problems to implement VCR-like interactions for user's convenience in the multicast streaming system under considering the limited-server and the network's bandwidth in the multicast-transmission system. Therefore, the proper solution of settling such a problem is necessary. Thus, this paper which revised P2Patching[l] proposes LGST(Level Group Streaming Technique) which supports the VCR's function through cooperation among peers with heterogeneous bandwidth under the environment of P2P. This strategy can reduce latency by improving the acceptance of server and using the bandwidth of network efficiently. And for evaluate the proposed scheme's performance, I simulated the performance of streaming delivery topology and streaming quality in comparison with P2Patching. In evaluation to service request refusal ratio and service quality according to bandwidth decrement, the result of simulation shows that proposed LGST improves about $11{\sim}18%$ of performance than P2Patching. In the test of latency recovery according to fault probability and influence of VCR function operation duration, it shows similar performance.

The Psychosocial Aspects of the Patients with Chronic Hepatitis B (만성 B형 간질환 환자의 정신사회적 측면)

  • Kim, Jin-Sung
    • Korean Journal of Psychosomatic Medicine
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    • v.8 no.1
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    • pp.3-10
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    • 2000
  • Objectives : The author wanted to summarize the psychiatric and social aspects of the patients with hepatitis B virus infection. Methods : The author reviewed all pertinent citations in the Medline database from 1966 to 1999. Results : Psychiatric problems in this population include delirium, psychotic disorder due to general medical condition(especially mania), anxiety, depression, adjustment disorder, alcohol abuse/dependence, and drug abuse/dependence. Social aspects of the patients with hepatitis B viral infection relate to the stigma of being a carrier, guilty feeling about infection, guilty feeling about increased family burden, impacts of having hepatitis on interpersonal relations, sexual difficulties, and job loss with increased financial burden, and health care worker's refusal. Conclusions : Appropriate early educational counseling interventions regarding the expected course and psychosocial intervention should be tailored to the sociocultural needs of special populations. Those interventions will increase compliance of treatment and prevent progression to hepatocellalar carcinoma from hepatitis.

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The Effects of Smoking Prevention Education on High School Students (고등학생의 흡연예방교육 효과분석)

  • 김수영;정영숙
    • Korean Journal of Health Education and Promotion
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    • v.20 no.2
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    • pp.81-94
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    • 2003
  • Purpose: This study was to develop a smoking prevention educational program and to verify the effects of the program as an intervention to prevent smoking among high school students. Method: This study was designed by using a nonequivalent Quasi-experimental control group pretest-posttest. The instruments used in this study were scale on smoking prevention knowledge and attitude. The experimental group received 8 smoking prevention educational classes, each lasting 50-minutes every week. The collected data was analyzed by real number and percentage, Chi-Square test, t-test, ANCOVA, Pearson correlation coefficients, Cronbach's α, using the SPSS WIN 11.0 program. Result: 1) After the completion of the smoking prevention education program, the experimental group's smoking knowledge scores(16.05±3.40) were higher than the control group's scores(14.39±3.81). Mean scores of smoking knowledge were statistically significantly different between the experimental group and the control group(F=38.700, p=.000). 2) After the completion of the smoking prevention education program, the experimental group's smoking prevention attitude scores were 47.52±5.30 and the control group's scores were 47.l0±5.54. Mean scores of attitude toward smoking prevention were statistically significantly different between the experimental group and the control group. 3) The relationship between smoking knowledge and attitude toward smoking prevention indicated positive correlation though the degree of positive correlation was low. Conclusion: Smoking prevention educational program which included self-search, smoking influence, adolescent smoking, family smoking, secondary smoking, self assertion using refusal skill was proved to be effective as an intervention for smoking prevention in high school students.

A Study on the Dome Plan of S. M. del Fiore Church of F. Brunelleschi (브루넬레스키의 산타 마리아 델 휘오레 교회의 돔계획에 관한 연구)

  • Kim, Seok-Man
    • Journal of architectural history
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    • v.21 no.5
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    • pp.19-32
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    • 2012
  • The purpose of this paper is a study on the dome plan of S. M. del Fiore Church of F. Brunelleschi. The results of study are as follows: 1. The planning of floor, elevation and cross section plan of S. M. del Fiore church is basically planned by each other correlation. In particular, the octangular form of geometrical standard which is formed with altar as the center at the crossing part is important component elements which is decided by not only the dome, but form and size of the drum and floor plan form of the lantern 2. The dome which has been planned by F. Brunelleshi has completed the new dome, preserving gothic thought intended by the church plan after study on architecture of ancient Rome with Pantheon. And the dome which is a main space of church through all aspects of plan, structure, function and construction about the dome is a opportunity in the beginning of Renaissance architecture which is a new epoch and a turning point of architecture on various point of view. 3. The dome which is constructed by F. Brunelleshi has been planned through the innovative solution by the refusal of traditional semicircle form dome, centering use and creation double-shell structure form for the first time in history. And the construction of dome has been solved with the invention of various construction equipments and machineries, the stone rib planned for connection and reinforcement about shells of the octangular form, the support method for reduction the gravity of bricklayers work and the brick work of nock-patterned shape which is masonry construction method of the architecture of ancient Rome.